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Therapeutic modulation of Notch signalling--are we there yet?
- Published in:
- 2014
- By:
- Publication type:
- journal article
Identification, discrimination and heterogeneity of fibroblasts.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30633-9
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- Publication type:
- Article
Identification, discrimination and heterogeneity of fibroblasts.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30633-9
- By:
- Publication type:
- Article
Active immunotherapy reduces NOTCH3 deposition in brain capillaries in a CADASIL mouse model.
- Published in:
- EMBO Molecular Medicine, 2023, v. 15, n. 2, p. 1, doi. 10.15252/emmm.202216556
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- Publication type:
- Article
Sex differences and risk factors for bleeding in Alagille syndrome.
- Published in:
- EMBO Molecular Medicine, 2022, v. 14, n. 12, p. 1, doi. 10.15252/emmm.202215809
- By:
- Publication type:
- Article
Constitutive activation of NF-?B and T-cell leukemia/lymphoma in Notch3 transgenic mice.
- Published in:
- EMBO Journal, 2000, v. 19, n. 13, p. 3337, doi. 10.1093/emboj/19.13.3337
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- Publication type:
- Article
Roles of Notch Signaling in the Tumor Microenvironment.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 11, p. 6241, doi. 10.3390/ijms23116241
- By:
- Publication type:
- Article
Expression of Trk Receptors during Cartilage Differentiation.
- Published in:
- Annals of the New York Academy of Sciences, 1996, v. 785, n. 1, p. 298, doi. 10.1111/j.1749-6632.1996.tb56289.x
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- Publication type:
- Article
Transient expression of a human β-actin promoter/ lacZ gene introduced into mouse embryos correlates with a low degree of methylation.
- Published in:
- Molecular Reproduction & Development, 1993, v. 34, n. 2, p. 149, doi. 10.1002/mrd.1080340206
- By:
- Publication type:
- Article
DUCT reveals architectural mechanisms contributing to bile duct recovery in a mouse model for Alagille syndrome.
- Published in:
- eLife, 2021, p. 1, doi. 10.7554/eLife.60916
- By:
- Publication type:
- Article
An Eya1-Notch axis specifies bipotential epibranchial differentiation in mammalian craniofacial morphogenesis.
- Published in:
- eLife, 2017, p. 1, doi. 10.7554/eLife.30126.001
- By:
- Publication type:
- Article
Blockade of tumor cell-intrinsic PD-L1 signaling enhances AURKA-targeted therapy in triple negative breast cancer.
- Published in:
- Frontiers in Oncology, 2024, p. 1, doi. 10.3389/fonc.2024.1384277
- By:
- Publication type:
- Article
Ly49A expression on T cells alters T cell selection.
- Published in:
- International Immunology, 2000, v. 12, n. 2, p. 215, doi. 10.1093/intimm/12.2.215
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- Publication type:
- Article
Expression pattern of Notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand–receptor interactions in intrathymic T cell development.
- Published in:
- International Immunology, 1999, v. 11, n. 7, p. 1017, doi. 10.1093/intimm/11.7.1017
- By:
- Publication type:
- Article
Elevated expression levels of an Ig transgene in mice links the IgH 3' enhancer to the regulation of IgH expression.
- Published in:
- International Immunology, 1996, v. 8, n. 7, p. 1149, doi. 10.1093/intimm/8.7.1149
- By:
- Publication type:
- Article
A Critical Role for Sox9 in Notch-Induced Astrogliogenesis and Stem Cell Maintenance.
- Published in:
- Stem Cells, 2013, v. 31, n. 4, p. 741, doi. 10.1002/stem.1320
- By:
- Publication type:
- Article
Human Fis1 regulates mitochondrial dynamics through inhibition of the fusion machinery.
- Published in:
- EMBO Journal, 2019, v. 38, n. 8, p. N.PAG, doi. 10.15252/embj.201899748
- By:
- Publication type:
- Article
Mechanism of gamma-secretase-mediated APP processing and modulation
- Published in:
- 2012
- By:
- Publication type:
- Abstract
MIEF1/2 orchestrate mitochondrial dynamics through direct engagement with both the fission and fusion machineries.
- Published in:
- BMC Biology, 2021, v. 19, n. 1, p. 1, doi. 10.1186/s12915-021-01161-7
- By:
- Publication type:
- Article
Characterization of Notch3-deficient mice: Normal embryonic development and absence of genetic interactions with a Notch1 mutation.
- Published in:
- Genesis: The Journal of Genetics & Development, 2003, v. 37, n. 3, p. 139, doi. 10.1002/gene.10241
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- Publication type:
- Article
Cross-talk between the Notch and TGF-β signaling pathways mediated by interaction of the Notch intracellular domain with Smad.
- Published in:
- Journal of Cell Biology, 2003, v. 163, n. 4, p. 723, doi. 10.1083/jcb.200305112
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- Publication type:
- Article
Regulation of Mammalian Mitochondrial Dynamics: Opportunities and Challenges.
- Published in:
- Frontiers in Endocrinology, 2020, v. 11, p. 1, doi. 10.3389/fendo.2020.00374
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- Publication type:
- Article
Notch Signaling Maintains Neural Rosette Polarity
- Published in:
- PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0062959
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- Publication type:
- Article
Notch and neurogenesis.
- Published in:
- Journal of Neuroscience Research, 1998, v. 54, n. 2, p. 125, doi. 10.1002/(SICI)1097-4547(19981015)54:2<125::AID-JNR1>3.0.CO;2-G
- By:
- Publication type:
- Article
Emerging links between cerebrovascular and neurodegenerative diseases—a special role for pericytes.
- Published in:
- EMBO Reports, 2019, v. 20, n. 11, p. N.PAG, doi. 10.15252/embr.201948070
- By:
- Publication type:
- Article
Generating specificity and diversity in the transcriptional response to hypoxia.
- Published in:
- 2009
- By:
- Publication type:
- journal article
Transgenic analysis of central nervous system development and regeneration.
- Published in:
- Acta Anaesthesiologica Scandinavica, 1997, v. 41, p. 116, doi. 10.1111/j.1399-6576.1997.tb05524.x
- By:
- Publication type:
- Article
Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission.
- Published in:
- EMBO Journal, 2011, v. 30, n. 14, p. 2762, doi. 10.1038/emboj.2011.198
- By:
- Publication type:
- Article
Oh no, Notch again!
- Published in:
- BioEssays, 2001, v. 23, n. 1, p. 3, doi. 10.1002/1521-1878(200101)23:1<3::aid-bies1001>3.3.co;2-6
- By:
- Publication type:
- Article
A growing family of Notch ligands.
- Published in:
- BioEssays, 1998, v. 20, n. 2, p. 103, doi. 10.1002/(SICI)1521-1878(199802)20:2<103::AID-BIES1>3.0.CO;2-U
- By:
- Publication type:
- Article
Decoding breast cancer tissue-stroma interactions using species-specific sequencing.
- Published in:
- Breast Cancer Research, 2015, v. 17, n. 1, p. 1, doi. 10.1186/s13058-015-0616-x
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- Publication type:
- Article
Decoding breast cancer tissue–stroma interactions using species-specific sequencing.
- Published in:
- Breast Cancer Research, 2015, v. 17, n. 1, p. 1, doi. 10.1186/s13058-015-0616-x
- By:
- Publication type:
- Article
Cell surface antigen profiling using a novel type of antibody array immobilised to plasma ion-implanted polycarbonate.
- Published in:
- Cellular & Molecular Life Sciences, 2014, v. 71, n. 19, p. 3841, doi. 10.1007/s00018-014-1595-2
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- Publication type:
- Article
PKCζ regulates Notch receptor routing and activity in a Notch signaling-dependent manner.
- Published in:
- Cell Research, 2014, v. 24, n. 4, p. 433, doi. 10.1038/cr.2014.34
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- Publication type:
- Article
Revisiting the peripheral sink hypothesis: inhibiting BACE1 activity in the periphery does not alter β-amyloid levels in the CNS.
- Published in:
- Journal of Neurochemistry, 2015, v. 132, n. 4, p. 477, doi. 10.1111/jnc.12937
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- Publication type:
- Article
High levels of Notch signaling down-regulate Numb and Numblike.
- Published in:
- Journal of Cell Biology, 2006, v. 175, n. 4, p. 535, doi. 10.1083/jcb.200602009
- By:
- Publication type:
- Article
An Evolutionarily Conserved Region in the Second lntron of the Human Nestin Gene Directs Gene Exmession to CNS Progenitor Cells and to Early Neural Ciest Cells.
- Published in:
- European Journal of Neuroscience, 1997, v. 9, n. 3, p. 452, doi. 10.1111/j.1460-9568.1997.tb01622.x
- By:
- Publication type:
- Article
Adult Nestin-expressing Subependymal Cells Differentiate to Astrocytes in Response to Brain Injury.
- Published in:
- European Journal of Neuroscience, 1997, v. 9, n. 1, p. 65, doi. 10.1111/j.1460-9568.1997.tb01354.x
- By:
- Publication type:
- Article
Regulation of mitochondrial dynamics: convergences and divergences between yeast and vertebrates.
- Published in:
- Cellular & Molecular Life Sciences, 2013, v. 70, n. 6, p. 951, doi. 10.1007/s00018-012-1066-6
- By:
- Publication type:
- Article
Notch and Wnt Dysregulation and Its Relevance for Breast Cancer and Tumor Initiation.
- Published in:
- Biomedicines, 2018, v. 6, n. 4, p. 101, doi. 10.3390/biomedicines6040101
- By:
- Publication type:
- Article
γ-Secretase complexes containing N- and C-terminal fragments of different presenilin origin retain normal γ-secretase activity.
- Published in:
- Journal of Neurochemistry, 2005, v. 95, n. 3, p. 880, doi. 10.1111/j.1471-4159.2005.03415.x
- By:
- Publication type:
- Article
Aph-1 interacts at the cell surface with proteins in the activeγ-secretase complex and membrane-tethered Notch.
- Published in:
- Journal of Neurochemistry, 2005, v. 92, n. 5, p. 1010, doi. 10.1111/j.1471-4159.2004.02926.x
- By:
- Publication type:
- Article
Co-expressed presenilin 1 NTF and CTF form functional γ-secretase complexes in cells devoid of full-length protein.
- Published in:
- Journal of Neurochemistry, 2004, v. 89, n. 1, p. 44, doi. 10.1046/j.1471-4159.2003.02298.x
- By:
- Publication type:
- Article
Frequency and distribution of Notch mutations in tumor cell lines.
- Published in:
- BMC Cancer, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12885-015-1278-x
- By:
- Publication type:
- Article
Notch signalling controls pancreatic cell differentiation.
- Published in:
- Nature, 1999, v. 400, n. 6747, p. 877, doi. 10.1038/23716
- By:
- Publication type:
- Article
Impact of Epithelial-Stromal Interactions on Peritumoral Fibroblasts in Ductal Carcinoma in Situ.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Left ventricular hypertrophy and metabolic resetting in the Notch3-deficient adult mouse heart.
- Published in:
- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-42010-7
- By:
- Publication type:
- Article
Influence of glycosylphosphatidylinositol-linked H-2D.
- Published in:
- European Journal of Immunology, 1996, v. 26, n. 9, p. 2127, doi. 10.1002/eji.1830260925
- By:
- Publication type:
- Article
Lipopolysaccharide-dependent transactivation of the temporally regulated immunoglobulin heavy chain 3′ enhancer.
- Published in:
- European Journal of Immunology, 1994, v. 24, n. 7, p. 1671, doi. 10.1002/eji.1830240732
- By:
- Publication type:
- Article
Publisher Correction: Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination.
- Published in:
- 2020
- By:
- Publication type:
- Correction Notice