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Cognitive Effects of Simulated Galactic Cosmic Radiation Are Mediated by ApoE Status, Sex, and Environment in APP Knock-In Mice.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 17, p. 9379, doi. 10.3390/ijms25179379
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- Article
Plasma and CSF biomarkers of aging and cognitive decline in Caribbean vervets.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 8, p. 5460, doi. 10.1002/alz.14038
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- Publication type:
- Article
Long-Term, Sex-Specific Effects of GCRsim and Gamma Irradiation on the Brains, Hearts, and Kidneys of Mice with Alzheimer's Disease Mutations.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 16, p. 8948, doi. 10.3390/ijms25168948
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- Article
Regional distribution of TDP-43 inclusions in Alzheimer disease (AD) brains: Their relation to AD common pathology.
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- Neuropathology, 2009, v. 29, n. 5, p. 566, doi. 10.1111/j.1440-1789.2009.01017.x
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- Article
Aducanumab produced a clinically meaningful benefit in association with amyloid lowering.
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- Alzheimer's Research & Therapy, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13195-021-00838-z
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- Article
MER5101, a Novel Aßl-15:DT Conjugate Vaccine, Generates a Robust Anti-Aß Antibody Response and Attenuates A/3 Pathology and Cognitive Deficits in APPswe/PSlΔE9 Transgenic Mice.
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- Journal of Neuroscience, 2013, v. 33, n. 16, p. 7027, doi. 10.1523/JNEUROSCI.5924-12.2013
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- Article
L-3-n-Butylphthalide Improves Cognitive Impairment and Reduces Amyloid-β in a Transgenic Model of Alzheimer's Disease.
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- Journal of Neuroscience, 2010, v. 30, n. 24, p. 8180, doi. 10.1523/JNEUROSCI.0340-10.2010
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- Article
Complement C3 Deficiency Leads to Accelerated Amyloid β Plaque Deposition and Neurodegeneration and Modulation of the Microglia/Macrophage Phenotype in Amyloid Precursor Protein Transgenic Mice.
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- Journal of Neuroscience, 2008, v. 28, n. 25, p. 6333, doi. 10.1523/JNEUROSCI.0829-08.2008
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- Article
Amyloid β Protein Dimer-Containing Human CSF Disrupts Synaptic Plasticity: Prevention by Systemic Passive Immunization.
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- Journal of Neuroscience, 2008, v. 28, n. 16, p. 4231, doi. 10.1523/JNEUROSCI.5161-07.2008
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- Publication type:
- Article
Amyloid-Related Imaging Abnormalities in the Era of Anti-Amyloid Beta Monoclonal Antibodies for Alzheimer’s Disease: Recent Updates on Clinical and Imaging Features and MRI Monitoring.
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- Korean Journal of Radiology, 2024, v. 25, n. 8, p. 726, doi. 10.3348/kjr.2024.0105
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- Article
Osteopetrotic (op/op) mice have reduced microglia, no Aβ deposition, and no changes in dopaminergic neurons.
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- Journal of Neuroinflammation, 2007, v. 4, p. 31, doi. 10.1186/1742-2094-4-31
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- Article
Boosting with intranasal dendrimeric Aβ1-15 but not Aβ1-15 peptide leads to an effective immune response following a single injection of Aβ1-40/42 in APP-tg mice.
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- Journal of Neuroinflammation, 2006, v. 3, p. 14, doi. 10.1186/1742-2094-3-14
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- Article
Passive Aβ Immunotherapy: Current Achievements and Future Perspectives.
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- Molecules, 2018, v. 23, n. 5, p. 1068, doi. 10.3390/molecules23051068
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- Article
Deletion of tumor necrosis factor death receptor inhibits amyloid β generation and prevents learning and memory deficits in Alzheimer's mice.
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- Journal of Cell Biology, 2007, v. 178, n. 5, p. 829, doi. 10.1083/jcb.200705042
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- Article
APP processing is regulated by cytoplasmic phosphorylation.
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- Journal of Cell Biology, 2003, v. 163, n. 1, p. 83, doi. 10.1083/jcb.200301115
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- Article
De-repression of FOXO3a death axis by microRNA-132 and -212 causes neuronal apoptosis in Alzheimer's disease.
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- Human Molecular Genetics, 2013, v. 22, n. 15, p. 3077, doi. 10.1093/hmg/ddt164
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- Article
A coding variant in CR1 interacts with APOE-ɛ4 to influence cognitive decline.
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- Human Molecular Genetics, 2012, v. 21, n. 10, p. 2377
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- Publication type:
- Article
Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease.
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- Alzheimer's Research & Therapy, 2011, v. 3, n. 1, p. 1, doi. 10.1186/alzrt59
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- Article
Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice.
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- Science Translational Medicine, 2017, v. 9, n. 392, p. 1, doi. 10.1126/scitranslmed.aaf6295
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- Article
The Importance of Complement-Mediated Immune Signaling in Alzheimer's Disease Pathogenesis.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 2, p. 817, doi. 10.3390/ijms25020817
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- Publication type:
- Article
High-Energy, Whole-Body Proton Irradiation Differentially Alters Long-Term Brain Pathology and Behavior Dependent on Sex and Alzheimer's Disease Mutations.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 4, p. 3615, doi. 10.3390/ijms24043615
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- Article
Long-Term Sex- and Genotype-Specific Effects of 56 Fe Irradiation on Wild-Type and APPswe/PS1dE9 Transgenic Mice.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 24, p. 13305, doi. 10.3390/ijms222413305
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- Article
Combination of the Glutaminyl Cyclase Inhibitor PQ912 (Varoglutamstat) and the Murine Monoclonal Antibody PBD-C06 (m6) Shows Additive Effects on Brain Aβ Pathology in Transgenic Mice.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 21, p. 11791, doi. 10.3390/ijms222111791
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- Article
Traumatic Brain Injury in Aged Mice Induces Chronic Microglia Activation, Synapse Loss, and Complement-Dependent Memory Deficits.
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- International Journal of Molecular Sciences, 2018, v. 19, n. 12, p. 3753, doi. 10.3390/ijms19123753
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- Article
Dissecting the Contribution of Vascular Alterations and Aging to Alzheimer's Disease.
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- Molecular Neurobiology, 2016, v. 53, n. 6, p. 3793, doi. 10.1007/s12035-015-9319-7
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- Publication type:
- Article
Characterization of Aβ11-40/42 peptide deposition in Alzheimer’s disease and young Down’s syndrome brains: implication of N-terminally truncated Aβ species in the pathogenesis of Alzheimer’s disease.
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- Acta Neuropathologica, 2006, v. 112, n. 2, p. 163, doi. 10.1007/s00401-006-0077-5
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- Article
Phosphorylated Aβ peptides in human Down syndrome brain and different Alzheimer's-like mouse models.
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- Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-00959-w
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- Article
Stosowanie leku adukanumab przynosi klinicznie istotną korzyść związaną z obniżeniem poziomu amyloidu.
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- Current Neurology / Aktualno?ci Neurologiczne, 2021, v. 21, n. 2, p. 111, doi. 10.15557/AN.2021.0014
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- Article
Paving the Way for Therapy: The Second International Conference of the Trisomy 21 Research Society.
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- Molecular Syndromology, 2018, v. 9, n. 6, p. 279, doi. 10.1159/000494231
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- Article
Exosomes neutralize synaptic-plasticity-disrupting activity of Abeta assemblies in vivo.
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- Molecular Brain, 2013, v. 6, n. 1, p. 1, doi. 10.1186/1756-6606-6-47
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- Article
Immunotherapy targeting pyroglutamate-3 Aβ: prospects and challenges.
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- Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0115-2
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- Article
Immunotherapy for Alzheimer's disease: hoops and hurdles.
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- Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-36
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- Article
Increased DJ-1 expression under oxidative stress and in Alzheimer's disease brains.
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- Molecular Neurodegeneration, 2009, v. 4, p. 1, doi. 10.1186/1750-1326-4-12
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- Publication type:
- Article
Passive Immunization against Pyroglutamate-3 Amyloid-β Reduces Plaque Burden in Alzheimer-Like Transgenic Mice: A Pilot Study.
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- Neurodegenerative Diseases, 2012, v. 10, n. 1-4, p. 265, doi. 10.1159/000335913
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- Article
Developing Novel Immunogens for an Effective, Safe Alzheimer’s Disease Vaccine.
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- Neurodegenerative Diseases, 2005, v. 2, n. 5, p. 267, doi. 10.1159/000090367
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- Article
Temporal Characterization of the Amyloidogenic APPswe/PS1dE9;hAPOE4 Mouse Model of Alzheimer's Disease.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 11, p. 5754, doi. 10.3390/ijms25115754
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- Article
Prescribing anti‐amyloid immunotherapies to treat Alzheimer's disease: Fully informing patient decisions.
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- Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2023, v. 9, n. 4, p. 1, doi. 10.1002/trc2.12426
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- Publication type:
- Article
In Vivo Detection of Age- and Disease-Related Increases in Neuroinflammation by <sup>18</sup>F-GE180 TSPO MicroPET Imaging in Wild-Type and Alzheimer's Transgenic Mice.
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- Journal of Neuroscience, 2015, v. 35, n. 47, p. 15716, doi. 10.1523/JNEUROSCI.0996-15.2015
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- Publication type:
- Article
Complement C3-Deficient Mice Fail to Display Age-Related Hippocampal Decline.
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- Journal of Neuroscience, 2015, v. 35, n. 38, p. 13029, doi. 10.1523/JNEUROSCI.1698-15.2015
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- Article
A novel inducible complement C3 conditional knockout mouse model: Generation and characterization: Developing topics.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.047192
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- Article
Further understanding the connection between Alzheimer's disease and Down syndrome.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 7, p. 1065, doi. 10.1002/alz.12112
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- Article
Scientific Advising and Reviewing: On strengthening the bond between the Alzheimer's Association and the scientific community.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 7, p. 1095, doi. 10.1002/alz.12059
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- Article
P1‐092: PBD‐C06 – A NOVEL ANTI‐PGLU3‐Aβ ANTIBODY FOR IMMUNOTHERAPY AGAINST ALZHEIMER'S DISEASE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P270, doi. 10.1016/j.jalz.2019.06.647
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- Article
P1‐099: COMBINATION OF A GLUTAMINYL CYCLASE INHIBITOR (PQ912) AND A PYROGLUTAMATE‐Aβ SPECIFIC ANTIBODY (PBD‐M06) SHOWS ADDITIVE EFFECTS IN A MOUSE MODEL WITH ALZHEIMER'S DISEASE‐LIKE PATHOLOGY.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P309, doi. 10.1016/j.jalz.2018.06.101
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- Publication type:
- Article
UPDATE OF THE AMYLOID HYPOTHESIS: COMPLEMENT MODULATES THE GLIAL RESPONSE TO Aβ PLAQUES AND MEDIATES SYNAPSE LOSS.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1218, doi. 10.1016/j.jalz.2017.07.395
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- Publication type:
- Article
BENEFICIAL EFFECTS OF ANTI-INFLAMMATORY, RNS60, IN AGED APPSWE/PS1DE9 MICE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P860, doi. 10.1016/j.jalz.2016.06.1766
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- Article
Down syndrome and Alzheimer's disease: Common pathways, common goals.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 6, p. 700, doi. 10.1016/j.jalz.2014.10.007
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- Article
Active immunization against pyroGlu-3 Aβ generates high antibody titers and lowers plaque burden in APP transgenic mice
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- 2011
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- Publication type:
- Abstract
Aging, biomarkers and behavior in Caribbean vervets
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- 2010
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- Publication type:
- Abstract
Pyroglutamate 3 Abeta immunoreactivity in brains of mice, monkeys and humans
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- 2009
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- Publication type:
- Abstract