OpenURL Connection Search

Select item for more details and to access through your institution.

Development of a novel secondary phenotypic screen to identify hits within the mycobacterial protein synthesis pipeline.
Published in:
FASEB Bioadvances, 2020, v. 2, n. 10, p. 600, doi. 10.1096/fba.2020-00022
By:
- Burke, Christopher;
- Jankute, Monika;
- Moynihan, Patrick;
- Gonzalez del Rio, Ruben;
- Li, Xiaojun;
- Esquivias, Jorge;
- Lelièvre, Joël;
- Cox, Jonathan A. G.;
- Sacchettini, James;
- Besra, Gurdyal S.
Publication type:
Article
Novel inhibitors of Mycobacterium tuberculosis GuaB2 identified by a target based high-throughput phenotypic screen.
Published in:
Scientific Reports, 2016, p. 38986, doi. 10.1038/srep38986
By:
- Cox, Jonathan A. G.;
- Mugumbate, Grace;
- Del Peral, Laura Vela-Glez;
- Jankute, Monika;
- Abrahams, Katherine A.;
- Jervis, Peter;
- Jackenkroll, Stefan;
- Perez, Arancha;
- Alemparte, Carlos;
- Esquivias, Jorge;
- Lelièvre, Joël;
- Ramon, Fernando;
- Barros, David;
- Ballell, Lluis;
- Besra, Gurdyal S.
Publication type:
Article
Release of 50 new, drug-like compounds and their computational target predictions for open source anti-tubercular drug discovery.
Published in:
PLoS ONE, 2015, v. 10, n. 12, p. 1, doi. 10.1371/journal.pone.0142293
By:
- Rebollo-Lopez, María Jose;
- Lelièvre, Joël;
- Alvarez-Gomez, Daniel;
- Castro-Pichel, Julia;
- Martínez-Jiménez, Francisco;
- Papadatos, George;
- Kumar, Vinod;
- Colmenarejo, Gonzalo;
- Mugumbate, Grace;
- Hurle, Mark;
- Barroso, Vanessa;
- Young, Rob J.;
- Martinez-Hoyos, María;
- González del Río, Rubén;
- Bates, Robert H.;
- Lopez-Roman, Eva Maria;
- Mendoza-Losana, Alfonso;
- Brown, James R.;
- Alvarez-Ruiz, Emilio;
- Marti-Renom, Marc A.
Publication type:
Article
A New Set of Chemical Starting Points with Plasmodium falciparum Transmission-Blocking Potential for Antimalarial Drug Discovery.
Published in:
PLoS ONE, 2015, v. 10, n. 8, p. 1, doi. 10.1371/journal.pone.0135139
By:
- Almela, Maria Jesus;
- Lozano, Sonia;
- Lelièvre, Joël;
- Colmenarejo, Gonzalo;
- Coterón, José Miguel;
- Rodrigues, Janneth;
- Gonzalez, Carolina;
- Herreros, Esperanza
Publication type:
Article
Mycobacterial Dihydrofolate Reductase Inhibitors Identified Using Chemogenomic Methods and In Vitro Validation.
Published in:
PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0121492
By:
- Mugumbate, Grace;
- Abrahams, Katherine A.;
- Cox, Jonathan A. G.;
- Papadatos, George;
- van Westen, Gerard;
- Lelièvre, Joël;
- Calus, Szymon T.;
- Loman, Nicholas J.;
- Ballell, Lluis;
- Barros, David;
- Overington, John P.;
- Besra, Gurdyal S.
Publication type:
Article
A new piperidinol derivative targeting mycolic acid transport in Mycobacterium abscessus.
Published in:
Molecular Microbiology, 2016, v. 101, n. 3, p. 515, doi. 10.1111/mmi.13406
By:
- Dupont, Christian;
- Viljoen, Albertus;
- Dubar, Faustine;
- Blaise, Mickaël;
- Bernut, Audrey;
- Pawlik, Alexandre;
- Bouchier, Christiane;
- Brosch, Roland;
- Guérardel, Yann;
- Lelièvre, Joël;
- Ballell, Lluis;
- Herrmann, Jean‐Louis;
- Biot, Christophe;
- Kremer, Laurent
Publication type:
Article
Identification of KasA as the cellular target of an anti-tubercular scaffold.
Published in:
Nature Communications, 2016, v. 7, n. 9, p. 12581, doi. 10.1038/ncomms12581
By:
- Abrahams, Katherine A.;
- Chung, Chun-wa;
- Ghidelli-Disse, Sonja;
- Rullas, Joaquín;
- Rebollo-López, María José;
- Gurcha, Sudagar S.;
- Cox, Jonathan A. G.;
- Mendoza, Alfonso;
- Jiménez-Navarro, Elena;
- Martínez-Martínez, María Santos;
- Neu, Margarete;
- Shillings, Anthony;
- Homes, Paul;
- Argyrou, Argyrides;
- Casanueva, Ruth;
- Loman, Nicholas J.;
- Moynihan, Patrick J.;
- Lelièvre, Joël;
- Selenski, Carolyn;
- Axtman, Matthew
Publication type:
Article
A novel validated assay to support the discovery of new anti-malarial gametocytocidal agents.
Published in:
Malaria Journal, 2016, v. 15, p. 1, doi. 10.1186/s12936-016-1429-9
By:
- Bahamontes-Rosa, Noemí;
- Gomez-Lorenzo, María G.;
- Lelièvre, Joël;
- Rodriguez Alejandre, Ane;
- Almela, María Jesus;
- Lozano, Sonia;
- Herreros, Esperanza;
- Gamo, Francisco-Javier
Publication type:
Article
Activity of clinically relevant antimalarial drugs on Plasmodium falciparum mature gametocytes in an ATP bioluminescence "transmission blocking" assay.
Published in:
2012
By:
- Lelièvre, Joël;
- Almela, Maria Jesus;
- Lozano, Sonia;
- Miguel, Celia;
- Franco, Virginia;
- Leroy, Didier;
- Herreros, Esperanza
Publication type:
Abstract
Endoperoxide-based compounds: cross-resistance with artemisinins and selection of a Plasmodium falciparum lineage with a K13 non-synonymous polymorphism.
Published in:
2018
By:
- Paloque, Lucie;
- Lelièvre, Joël;
- Ouji, Manel;
- Haddou, Tanila Ben;
- Robert, Anne;
- Augereau, Jean-Michel;
- Meunier, Bernard;
- Benoit-Vical, Françoise;
- Witkowski, Benoit;
- Ménard, Didier;
- Ariey, Frédéric;
- Ben Haddou, Tanila
Publication type:
journal article

Found: 10