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Gene expression profiling in NOD mice reveals that B cells are highly educated by the pancreatic environment during autoimmune diabetes.
Published in:
Diabetologia, 2023, v. 66, n. 3, p. 551, doi. 10.1007/s00125-022-05839-7
By:
- Boldison, Joanne;
- Hopkinson, Jessica R.;
- Davies, Joanne;
- Pearson, James A.;
- Leete, Pia;
- Richardson, Sarah;
- Morgan, Noel G.;
- Wong, F. Susan
Publication type:
Article
Studies of insulin and proinsulin in pancreas and serum support the existence of aetiopathological endotypes of type 1 diabetes associated with age at diagnosis.
Published in:
Diabetologia, 2020, v. 63, n. 6, p. 1258, doi. 10.1007/s00125-020-05115-6
By:
- Leete, Pia;
- Oram, Richard A.;
- McDonald, Timothy J.;
- Shields, Beverley M.;
- Ziller, Clemens;
- TIGI study team;
- Roep, Bart O.;
- Tree, Timothy I.;
- Patel, Kashyap;
- Hammersley, Suzy;
- Bolt, Robert;
- Hill, Anita V.;
- Hattersley, Andrew T.;
- Richardson, Sarah J.;
- Morgan, Noel G.
Publication type:
Article
Unexpected subcellular distribution of a specific isoform of the Coxsackie and adenovirus receptor, CAR-SIV, in human pancreatic beta cells.
Published in:
Diabetologia, 2018, v. 61, n. 11, p. 2344, doi. 10.1007/s00125-018-4704-1
By:
- Ifie, Eseoghene;
- Russell, Mark A.;
- Dhayal, Shalinee;
- Leete, Pia;
- Sebastiani, Guido;
- Nigi, Laura;
- Dotta, Francesco;
- Marjomäki, Varpu;
- Eizirik, Decio L.;
- Morgan, Noel G.;
- Richardson, Sarah J.
Publication type:
Article
Islet cell hyperexpression of HLA class I antigens: a defining feature in type 1 diabetes.
Published in:
Diabetologia, 2016, v. 59, n. 11, p. 2448, doi. 10.1007/s00125-016-4067-4
By:
- Richardson, Sarah;
- Rodriguez-Calvo, Teresa;
- Gerling, Ivan;
- Mathews, Clayton;
- Kaddis, John;
- Russell, Mark;
- Zeissler, Marie;
- Leete, Pia;
- Krogvold, Lars;
- Dahl-Jørgensen, Knut;
- Herrath, Matthias;
- Pugliese, Alberto;
- Atkinson, Mark;
- Morgan, Noel
Publication type:
Article
Detection of enterovirus in the islet cells of patients with type 1 diabetes: what do we learn from immunohistochemistry? Reply to Hansson SF, Korsgren S, Pontén F et al [letter].
Published in:
2014
By:
- Richardson, Sarah;
- Leete, Pia;
- Dhayal, Shalinee;
- Russell, Mark;
- Oikarinen, Maarit;
- Laiho, Jutta;
- Svedin, Emma;
- Lind, Katharina;
- Rosenling, Therese;
- Chapman, Nora;
- Bone, Adrian;
- Foulis, Alan;
- Frisk, Gun;
- Flodström-Tullberg, Malin;
- Hober, Didier;
- Hyoty, Heikki;
- Pugliese, Alberto;
- Morgan, Noel
Publication type:
Letter
Evaluation of the fidelity of immunolabelling obtained with clone 5D8/1, a monoclonal antibody directed against the enteroviral capsid protein, VP1, in human pancreas.
Published in:
Diabetologia, 2014, v. 57, n. 2, p. 392, doi. 10.1007/s00125-013-3094-7
By:
- Richardson, Sarah;
- Leete, Pia;
- Dhayal, Shalinee;
- Russell, Mark;
- Oikarinen, Maarit;
- Laiho, Jutta;
- Svedin, Emma;
- Lind, Katharina;
- Rosenling, Therese;
- Chapman, Nora;
- Bone, Adrian;
- Foulis, Alan;
- Frisk, Gun;
- Flodstrom-Tullberg, Malin;
- Hober, Didier;
- Hyoty, Heikki;
- Morgan, Noel
Publication type:
Article
Differential expression of genes controlling lymphocyte differentiation and migration in two distinct endotypes of type 1 diabetes.
Published in:
Diabetic Medicine, 2023, v. 40, n. 9, p. 1, doi. 10.1111/dme.15155
By:
- Torabi, Forough;
- Vadakekolathu, Jayakumar;
- Wyatt, Rebecca;
- Leete, Pia;
- Tombs, Melissa A.;
- Richardson, Carolyn C.;
- Boocock, David J.;
- Turner, Mark D.;
- Morgan, Noel G.;
- Richardson, Sarah J.;
- Christie, Michael R.
Publication type:
Article
Single-cell RNAseq identifies clonally expanded antigen-specific T-cells following intradermal injection of gold nanoparticles loaded with diabetes autoantigen in humans.
Published in:
Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1276255
By:
- Hanna, Stephanie J.;
- Thayer, Terri C.;
- Robinson, Emma J. S.;
- Vinh, Ngoc-Nga;
- Williams, Nigel;
- Landry, Laurie G.;
- Andrews, Robert;
- Qi Zhuang Siah;
- Leete, Pia;
- Wyatt, Rebecca;
- McAteer, Martina A.;
- Nakayama, Maki;
- Wong, F. Susan;
- Yang, Jennie H. M.;
- Tree, Timothy I. M.;
- Ludvigsson, Johnny;
- Dayan, Colin M.;
- Tatovic, Danijela
Publication type:
Article
Footprints of Immune Cells in the Pancreas in Type 1 Diabetes; to "B" or Not to "B": Is That Still the Question?
Published in:
Frontiers in Endocrinology, 2021, v. 11, p. N.PAG, doi. 10.3389/fendo.2021.617437
By:
- Leete, Pia;
- Morgan, Noel G.
Publication type:
Article
Research Independence in Academia—'The holy grail' and beyond.
Published in:
Diabetic Medicine, 2024, v. 41, n. 8, p. 1, doi. 10.1111/dme.15406
By:
- Nasteska, Daniela;
- Leete, Pia
Publication type:
Article
Type 1 diabetes in the pancreas: A histological perspective.
Published in:
Diabetic Medicine, 2023, v. 40, n. 12, p. 1, doi. 10.1111/dme.15228
By:
- Leete, Pia
Publication type:
Article
Islet inflammation in human type 1 diabetes mellitus.
Published in:
IUBMB Life, 2014, v. 66, n. 11, p. 723, doi. 10.1002/iub.1330
By:
- Morgan, Noel G.;
- Leete, Pia;
- Foulis, Alan K.;
- Richardson, Sarah J.
Publication type:
Article
C-Peptide Decline in Type 1 Diabetes Has Two Phases: An Initial Exponential Fall and a Subsequent Stable Phase.
Published in:
2018
By:
- Shields, Beverley M.;
- McDonald, Timothy J.;
- Oram, Richard;
- Hill, Anita;
- Hudson, Michelle;
- Leete, Pia;
- Pearson, Ewan R.;
- Richardson, Sarah J.;
- Morgan, Noel G.;
- Hattersley, Andrew T.;
- TIGI Consortium
Publication type:
journal article
The Effect of Age on the Progression and Severity of Type 1 Diabetes: Potential Effects on Disease Mechanisms.
Published in:
2018
By:
- Leete, Pia;
- Mallone, Roberto;
- Richardson, Sarah J.;
- Sosenko, Jay M.;
- Redondo, Maria J.;
- Evans-Molina, Carmella
Publication type:
journal article
Circulating C-Peptide Levels in Living Children and Young People and Pancreatic β-Cell Loss in Pancreas Donors Across Type 1 Diabetes Disease Duration.
Published in:
2022
By:
- Carr, Alice L.J.;
- Inshaw, Jamie R.J.;
- Flaxman, Christine S.;
- Leete, Pia;
- Wyatt, Rebecca C.;
- Russell, Lydia A.;
- Palmer, Matthew;
- Prasolov, Dmytro;
- Worthington, Thomas;
- Hull, Bethany;
- Wicker, Linda S.;
- Dunger, David B.;
- Oram, Richard A.;
- Morgan, Noel G.;
- Todd, John A.;
- Richardson, Sarah J.;
- Besser, Rachel E.J.
Publication type:
journal article
Altered β-Cell Prohormone Processing and Secretion in Type 1 Diabetes.
Published in:
Diabetes, 2021, v. 70, n. 5, p. 1038, doi. 10.2337/dbi20-0034
By:
- Rodriguez-Calvo, Teresa;
- Yi-Chun Chen;
- Verchere, C. Bruce;
- Haataja, Leena;
- Arvan, Peter;
- Leete, Pia;
- Richardson, Sarah J.;
- Morgan, Noel G.;
- Wei-Jun Qian;
- Pugliese, Alberto;
- Atkinson, Mark;
- Evans-Molina, Carmella;
- Sims, Emily K.
Publication type:
Article
HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of Islet β-Cells From Donors With Type 1 Diabetes.
Published in:
2019
By:
- Russell, Mark A.;
- Richardson, Sarah J.;
- Leete, Pia;
- Morgan, Noel G.;
- Derr, Alan G.;
- Kucukural, Alper;
- Garber, Manuel G.;
- Yang, Chaoxing;
- Redick, Sambra D.;
- Chaoxing Yang;
- Babon, Jenny Aurielle B.;
- Kent, Sally C.;
- Harlan, David M.;
- Blodgett, David M.;
- Krogvold, Lars;
- Dahl-Jørgensen, Knut;
- Bottino, Rita;
- Brissova, Marcela;
- Powers, Alvin C.;
- Spaeth, Jason M.
Publication type:
journal article
Differential Insulitic Profiles Determine the Extent of β-Cell Destruction and the Age at Onset of Type 1 Diabetes.
Published in:
2016
By:
- Leete, Pia;
- Willcox, Abby;
- Krogvold, Lars;
- Dahl-Jørgensen, Knut;
- Foulis, Alan K.;
- Richardson, Sarah J.;
- Morgan, Noel G.
Publication type:
journal article
Detection of a Low-Grade Enteroviral Infection in the Islets of Langerhans of Living Patients Newly Diagnosed With Type 1 Diabetes.
Published in:
Diabetes, 2015, v. 64, n. 5, p. 1682, doi. 10.2337/db14-1370
By:
- Krogvold, Lars;
- Edwin, Bjørn;
- Buanes, Trond;
- Frisk, Gun;
- Skog, Oskar;
- Anagandula, Mahesh;
- Korsgren, Olle;
- Undlien, Dag;
- Eike, Morten C.;
- Richardson, Sarah J.;
- Leete, Pia;
- Morgan, Noel G.;
- Oikarinen, Sami;
- Oikarinen, Maarit;
- Laiho, Jutta E.;
- Hyöty, Heikki;
- Ludvigsson, Johnny;
- Hanssen, Kristian F.;
- Dahl-Jørgensen, Knut
Publication type:
Article
Blood and Islet Phenotypes Indicate Immunological Heterogeneity in Type 1 Diabetes.
Published in:
Diabetes, 2014, v. 63, n. 11, p. 3835, doi. 10.2337/db14-0365
By:
- Arif, Sefi;
- Leete, Pia;
- Nguyen, Vy;
- Marks, Katherine;
- Nor, Nurhanani Mohamed;
- Estorninho, Megan;
- Kronenberg-Versteeg, Deborah;
- Bingley, Polly J.;
- Todd, John A.;
- Guy, Catherine;
- Dunger, David B.;
- Powrie, Jake;
- Willcox, Abby;
- Foulis, Alan K.;
- Richardson, Sarah J.;
- de Rinaldis, Emanuele;
- Morgan, Noel G.;
- Lorenc, Anna;
- Peakman, Mark
Publication type:
Article

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