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In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation.
Published in:
2007
By:
- Seshasayee, Dhaya;
- Lee, Wyne P.;
- Meijuan Zhou;
- Jean Shu;
- Suto, Eric;
- Juan Zhang;
- Diehl, Laurie;
- Austin, Cary D.;
- Gloria Meng, Y.;
- Martha Tan;
- Bullens, Sherron L.;
- Seeber, Stefan;
- Fuentes, Maria E.;
- Labrijn, Aran F.;
- Graus, Yvo M. F.;
- Miller, Lisa A.;
- Schelegle, Edward S.;
- Hyde, Dallas M.;
- Wu, Lawren C.;
- Hymowitz, Sarah G.
Publication type:
journal article
The Hippo pathway effector TAZ induces TEAD-dependent liver inflammation and tumors.
Published in:
Science Signaling, 2018, v. 11, n. 547, p. 1, doi. 10.1126/scisignal.aaj1757
By:
- Hagenbeek, Thijs J.;
- Webster, Joshua D.;
- Kljavin, Noelyn M.;
- Chang, Matthew T.;
- Pham, Trang;
- Lee, Ho-June;
- Klijn, Christiaan;
- Cai, Allen G.;
- Totpal, Klara;
- Ravishankar, Buvana;
- Yang, Naiying;
- Lee, Da-Hye;
- Walsh, Kevin B.;
- Hatzivassiliou, Georgia;
- de la Cruz, Cecile C.;
- Gould, Stephen E.;
- Wu, Xiumin;
- Lee, Wyne P.;
- Yang, Shuqun;
- Zhang, Zhixiang
Publication type:
Article
TGF-β1 induces bone closure of skull defects: Temporal dynamics of bone formation in defects exposed to rhTGF-β1.
Published in:
Journal of Bone & Mineral Research, 1993, v. 8, n. 6, p. 753, doi. 10.1002/jbmr.5650080614
By:
- Beck, L. Steven;
- Amento, Edward P.;
- Xu, Yvette;
- Deguzman, Leo;
- Lee, Wyne P.;
- Nguyen, Tue;
- Gillett, Nancy A.
Publication type:
Article
Rapid publication TGF-β1 induces bone closure of skull defects.
Published in:
Journal of Bone & Mineral Research, 1991, v. 6, n. 11, p. 1257, doi. 10.1002/jbmr.5650061117
By:
- Beck, L. Steven;
- Deguzman, Leo;
- Lee, Wyne P.;
- Xu, Yvette;
- McFatridge, Lorrie A.;
- Gillett, Nancy A.;
- Amento, Edward P.
Publication type:
Article
In vivo induction of bone by recombinant human transforming growth factor β1.
Published in:
Journal of Bone & Mineral Research, 1991, v. 6, n. 9, p. 961, doi. 10.1002/jbmr.5650060910
By:
- Beck, L. Steven;
- Ammann, Arthur J.;
- Aufdemorte, Thomas B.;
- Deguzman, Leo;
- Xu, Yvette;
- Lee, Wyne P.;
- McFatridge, Lorrie A.;
- Chen, Theresa L.
Publication type:
Article
Targeted depletion of lymphotoxin-α–expressing TH1 and TH17 cells inhibits autoimmune disease.
Published in:
Nature Medicine, 2009, v. 15, n. 7, p. 766, doi. 10.1038/nm.1984
By:
- Chiang, Eugene Y.;
- Kolumam, Ganesh A.;
- Xin Yu;
- Francesco, Michelle;
- Ivelja, Sinisa;
- Peng, Ivan;
- Gribling, Peter;
- Shu, Jean;
- Lee, Wyne P.;
- Refino, Canio J.;
- Balazs, Mercedesz;
- Paler-Martinez, Andres;
- Nguyen, Allen;
- Young, Judy;
- Barck, Kai H.;
- Carano, Richard A. D.;
- Ferrando, Ron;
- Diehl, Lauri;
- Chatterjea, Devavani;
- Grogan, Jane L.
Publication type:
Article
The peptide symporter SLC15a4 is essential for the development of systemic lupus erythematosus in murine models.
Published in:
PLoS ONE, 2021, v. 16, n. 1, p. 1, doi. 10.1371/journal.pone.0244439
By:
- Katewa, Arna;
- Suto, Eric;
- Hui, Jessica;
- Heredia, Jose;
- Liang, Jie;
- Hackney, Jason;
- Anderson, Keith;
- Alcantar, Tuija M.;
- Bacarro, Natasha;
- Dunlap, Debra;
- Eastham, Jeffrey;
- Paler-Martinez, Andres;
- Rairdan, Xin Y.;
- Modrusan, Zora;
- Lee, Wyne P.;
- Austin, Cary D.;
- Lafkas, Daniel;
- Ghilardi, Nico
Publication type:
Article
Cryopyrin activates the inflammasome in response to toxins and ATP.
Published in:
Nature, 2006, v. 440, n. 7081, p. 228, doi. 10.1038/nature04515
By:
- Mariathasan, Sanjeev;
- Weiss, David S.;
- Newton, Kim;
- McBride, Jacqueline;
- O'Rourke, Karen;
- Roose-Girma, Meron;
- Lee, Wyne P.;
- Weinrauch, Yvette;
- Monack, Denise M.;
- Dixit, Vishva M.
Publication type:
Article
Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation.
Published in:
Nature Immunology, 2014, v. 15, n. 2, p. 161, doi. 10.1038/ni.2795
By:
- Vander Lugt, Bryan;
- Khan, Aly A;
- Hackney, Jason A;
- Agrawal, Smita;
- Lesch, Justin;
- Zhou, Meijuan;
- Lee, Wyne P;
- Park, Summer;
- Xu, Min;
- DeVoss, Jason;
- Spooner, Chauncey J;
- Chalouni, Cecile;
- Delamarre, Lelia;
- Mellman, Ira;
- Singh, Harinder
Publication type:
Article
IgE+ memory B cells and plasma cells generated through a germinal-center pathway.
Published in:
Nature Immunology, 2013, v. 14, n. 12, p. 1302, doi. 10.1038/ni.2770
By:
- Talay, Oezcan;
- Yan, Donghong;
- Brightbill, Hans D;
- Straney, Elizabeth E M;
- Zhou, Meijuan;
- Ladi, Ena;
- Lee, Wyne P;
- Egen, Jackson G;
- Austin, Cary D;
- Xu, Min;
- Wu, Lawren C
Publication type:
Article
Specification of type 2 innate lymphocytes by the transcriptional determinant Gfi1.
Published in:
Nature Immunology, 2013, v. 14, n. 12, p. 1229, doi. 10.1038/ni.2743
By:
- Spooner, Chauncey J;
- Lesch, Justin;
- Yan, Donghong;
- Khan, Aly A;
- Abbas, Alex;
- Ramirez-Carrozzi, Vladimir;
- Zhou, Meijuan;
- Soriano, Robert;
- Eastham-Anderson, Jeffrey;
- Diehl, Lauri;
- Lee, Wyne P;
- Modrusan, Zora;
- Pappu, Rajita;
- Xu, Min;
- DeVoss, Jason;
- Singh, Harinder
Publication type:
Article
Reply to "On the differentiation of mouse IgE+ cells".
Published in:
Nature Immunology, 2012, v. 13, n. 7, p. 623, doi. 10.1038/ni.2323
By:
- Talay, Oezcan;
- Yan, Donghong;
- Brightbill, Hans D;
- Straney, Elizabeth E M;
- Zhou, Meijuan;
- Ladi, Ena;
- Lee, Wyne P;
- Egen, Jackson G;
- Austin, Cary D;
- Xu, Min;
- Wu, Lawren C
Publication type:
Article
IgE+ memory B cells and plasma cells generated through a germinal-center pathway.
Published in:
Nature Immunology, 2012, v. 13, n. 4, p. 396, doi. 10.1038/ni.2256
By:
- Talay, Oezcan;
- Yan, Donghong;
- Brightbill, Hans D;
- Straney, Elizabeth E M;
- Zhou, Meijuan;
- Ladi, Ena;
- Lee, Wyne P;
- Egen, Jackson G;
- Austin, Cary D;
- Xu, Min;
- Wu, Lawren C
Publication type:
Article
TACI-ligand interactions are required for T cell activation and collagen-induced arthritis in mice.
Published in:
Nature Immunology, 2001, v. 2, n. 7, p. 632, doi. 10.1038/89782
By:
- Wang, Hua;
- Marsters, Scot A.;
- Baker, Thad;
- Chan, Betty;
- Lee, Wyne P.;
- Fu, Ling;
- Tumas, Daniel;
- Yan, Minhong;
- Dixit, Vishva M.;
- Ashkenazi, Avi;
- Grewal, Iqbal S.
Publication type:
Article
Tumor suppressor BAP1 is essential for thymic development and proliferative responses of T lymphocytes.
Published in:
Science Immunology, 2018, v. 3, n. 22, p. 1, doi. 10.1126/sciimmunol.aal1953
By:
- Arenzana, Teresita L.;
- Lianoglou, Steve;
- Seki, Akiko;
- Eidenschenk, Celine;
- Cheung, Tommy;
- Seshasayee, Dhaya;
- Hagenbeek, Thijs;
- Sambandam, Arivazhagan;
- Noubade, Rajkumar;
- Peng, Ivan;
- Lesch, Justin;
- DeVoss, Jason;
- Wu, Xiumin;
- Lee, Wyne P.;
- Caplazi, Patrick;
- Webster, Joshua;
- Liu, Jinfeng;
- Pham, Victoria C.;
- Arnott, David;
- Lill, Jennie R.
Publication type:
Article
Potassium channels Kv1.3 and KCa3.1 cooperatively and compensatorily regulate antigen-specific memory T cell functions.
Published in:
Nature Communications, 2017, v. 8, n. 3, p. 14644, doi. 10.1038/ncomms14644
By:
- Chiang, Eugene Y.;
- Li, Tianbo;
- Jeet, Surinder;
- Peng, Ivan;
- Zhang, Juan;
- Lee, Wyne P.;
- DeVoss, Jason;
- Caplazi, Patrick;
- Chen, Jun;
- Warming, Søren;
- Hackos, David H.;
- Mukund, Susmith;
- Koth, Christopher M.;
- Grogan, Jane L.
Publication type:
Article
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf.
Published in:
Nature, 2004, v. 430, n. 6996, p. 213, doi. 10.1038/nature02664
By:
- Mariathasan, Sanjeev;
- Newton, Kim;
- Monack, Denise M.;
- Vucic, Domagoj;
- French, Dorothy M.;
- Lee, Wyne P.;
- Roose-Girma, Meron;
- Erickson, Sharon;
- Dixit, Vishva M.
Publication type:
Article
Glyburide inhibits the Cryopyrin/Nalp3 inflammasome.
Published in:
Journal of Cell Biology, 2009, v. 187, n. 1, p. 61, doi. 10.1083/jcb.200903124
By:
- Lamkanfi, Mohamed;
- Mueller, James L.;
- Vitari, Alberto C.;
- Misaghi, Shahram;
- Fedorova, Anna;
- Deshayes, Kurt;
- Lee, Wyne P.;
- Hoffman, Hal M.;
- Dixit, Vishva M.
Publication type:
Article
IL-22R Ligands IL-20, IL-22, and IL-24 Promote Wound Healing in Diabetic db/db Mice.
Published in:
PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0170639
By:
- Kolumam, Ganesh;
- Wu, Xiumin;
- Lee, Wyne P.;
- Hackney, Jason A.;
- Zavala-Solorio, Jose;
- Gandham, Vineela;
- Danilenko, Dimitry M.;
- Arora, Puneet;
- Wang, Xiaoting;
- Ouyang, Wenjun
Publication type:
Article
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.
Published in:
Nature, 2015, v. 526, n. 7575, p. 666, doi. 10.1038/nature15541
By:
- Kayagaki, Nobuhiko;
- Stowe, Irma B.;
- Lee, Bettina L.;
- O'Rourke, Karen;
- Anderson, Keith;
- Warming, Søren;
- Cuellar, Trinna;
- Haley, Benjamin;
- Roose-Girma, Merone;
- Phung, Qui T.;
- Liu, Peter S.;
- Lill, Jennie R.;
- Li, Hong;
- Wu, Jiansheng;
- Kummerfeld, Sarah;
- Zhang, Juan;
- Lee, Wyne P.;
- Snipas, Scott J.;
- Salvesen, Guy S.;
- Morris, Lucy X.
Publication type:
Article
Interleukin-22 alleviates metabolic disorders and restores mucosal immunity in diabetes.
Published in:
Nature, 2014, v. 514, n. 7521, p. 237, doi. 10.1038/nature13564
By:
- Wang, Xiaoting;
- Ota, Naruhisa;
- Manzanillo, Paolo;
- Eidenschenk, Celine;
- Zhang, Juan;
- Lesch, Justin;
- Lee, Wyne P.;
- Ouyang, Wenjun;
- Kates, Lance;
- Zavala-Solorio, Jose;
- Ross, Jed;
- van Bruggen, Nicholas;
- Diehl, Lauri;
- Kolumam, Ganesh
Publication type:
Article
Non-canonical inflammasome activation targets caspase-11.
Published in:
Nature, 2011, v. 479, n. 7371, p. 117, doi. 10.1038/nature10558
By:
- Kayagaki, Nobuhiko;
- Warming, Søren;
- Lamkanfi, Mohamed;
- Walle, Lieselotte Vande;
- Louie, Salina;
- Dong, Jennifer;
- Newton, Kim;
- Qu, Yan;
- Liu, Jinfeng;
- Heldens, Sherry;
- Zhang, Juan;
- Lee, Wyne P.;
- Roose-Girma, Merone;
- Dixit, Vishva M.
Publication type:
Article
Dual B Cell Immunotherapy Is Superior to Individual Anti-CD20 Depletion or BAFF Blockade in Murine Models of Spontaneous or Accelerated Lupus.
Published in:
Arthritis & Rheumatology, 2015, v. 67, n. 1, p. 215, doi. 10.1002/art.38907
By:
- Lin, WeiYu;
- Seshasayee, Dhaya;
- Lee, Wyne P.;
- Caplazi, Patrick;
- McVay, Sami;
- Suto, Eric;
- Nguyen, Allen;
- Lin, Zhonghua;
- Sun, Yonglian;
- DeForge, Laura;
- Balazs, Mercedesz;
- Martin, Flavius;
- Zarrin, Ali A.
Publication type:
Article
Preclinical pharmacokinetics, pharmacodynamics, and activity of a humanized anti-CD40 antibody (SGN-40) in rodents and non-human primates.
Published in:
British Journal of Pharmacology, 2006, v. 148, n. 8, p. 1116, doi. 10.1038/sj.bjp.0706828
By:
- Kelley, Sean K.;
- Gelzleichter, Thomas;
- Dong Xie;
- Lee, Wyne P.;
- Darbonne, Walter C.;
- Qureshi, Ferhan;
- Kissler, Kim;
- Oflazoglu, Ezogelin;
- Grewal, Iqbal S.
Publication type:
Article
Publisher Correction: Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy.
Published in:
2018
By:
- Katschke, Kenneth J. Jr.;
- Xi, Hongkang;
- Cox, Christian;
- Truong, Tom;
- Malato, Yann;
- Lee, Wyne P.;
- McKenzie, Brent;
- Arceo, Rommel;
- Tao, Jianhua;
- Rangell, Linda;
- Reichelt, Mike;
- Diehl, Lauri;
- Elstrott, Justin;
- Weimer, Robby M.;
- van Lookeren Campagne, Menno
Publication type:
Correction Notice
Steroid-induced fibroblast growth factors drive an epithelial-mesenchymal inflammatory axis in severe asthma.
Published in:
Science Translational Medicine, 2022, v. 14, n. 641, p. 1, doi. 10.1126/scitranslmed.abl8146
By:
- Guidi, Riccardo;
- Xu, Daqi;
- Choy, David F.;
- Ramalingam, Thirumalai R.;
- Lee, Wyne P.;
- Modrusan, Zora;
- Liang, Yuxin;
- Marsters, Scot;
- Ashkenazi, Avi;
- Huynh, Alison;
- Mills, Jessica;
- Flanagan, Sean;
- Hambro, Shannon;
- Nunez, Victor;
- Leong, Laurie;
- Cook, Ashley;
- Tran, Tiffany Hao;
- Austin, Cary D.;
- Cao, Yi;
- Clarke, Christine
Publication type:
Article
In vivo antigen-driven plasmablast enrichment in combination with antigen-specific cell sorting to facilitate the isolation of rare monoclonal antibodies from human B cells.
Published in:
Nature Protocols, 2014, v. 9, n. 7, p. 1563, doi. 10.1038/nprot.2014.104
By:
- Lin, Zhonghua;
- Chiang, Nancy Y;
- Chai, Ning;
- Seshasayee, Dhaya;
- Lee, Wyne P;
- Balazs, Mercedesz;
- Nakamura, Gerald;
- Swem, Lee R
Publication type:
Article
The tumor suppressor BAP1 cooperates with BRAFV600E to promote tumor formation in cutaneous melanoma.
Published in:
Pigment Cell & Melanoma Research, 2019, v. 32, n. 2, p. 269, doi. 10.1111/pcmr.12735
By:
- Webster, Joshua D.;
- Pham, Trang H.;
- Wu, Xiumin;
- Hughes, Nicolas W.;
- Li, Zhongwu;
- Totpal, Klara;
- Lee, Ho‐June;
- Calses, Philamer C.;
- Chaurushiya, Mira S.;
- Stawiski, Eric W.;
- Modrusan, Zora;
- Chang, Matthew T.;
- Tran, Christopher;
- Lee, Wyne P.;
- Chalasani, Sreedevi;
- Hung, Jeffrey;
- Sharma, Neeraj;
- Chan, Sara;
- Hotzel, Kathy;
- Talevich, Eric
Publication type:
Article
Specific Btk inhibition suppresses B cell- and myeloid cell-mediated arthritis.
Published in:
Nature Chemical Biology, 2011, v. 7, n. 1, p. 41, doi. 10.1038/nchembio.481
By:
- Di Paolo, Julie A.;
- Huang, Tao;
- Balazs, Mercedesz;
- Barbosa, James;
- Barck, Kai H.;
- Bravo, Brandon J.;
- Carano, Richard A. D.;
- Darrow, James;
- Davies, Douglas R.;
- DeForge, Laura E.;
- Diehl, Lauri;
- Ferrando, Ronald;
- Gallion, Steven L.;
- Giannetti, Anthony M.;
- Gribling, Peter;
- Hurez, Vincent;
- Hymowitz, Sarah G.;
- Jones, Randall;
- Kropf, Jeffrey E.;
- Lee, Wyne P.
Publication type:
Article

Found: 29

In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation.

The Hippo pathway effector TAZ induces TEAD-dependent liver inflammation and tumors.

TGF-β<sub>1</sub> induces bone closure of skull defects: Temporal dynamics of bone formation in defects exposed to rhTGF-β<sub>1</sub>.

Rapid publication TGF-β<sub>1</sub> induces bone closure of skull defects.

In vivo induction of bone by recombinant human transforming growth factor β<sub>1</sub>.

Targeted depletion of lymphotoxin-α–expressing T<sub>H</sub>1 and T<sub>H</sub>17 cells inhibits autoimmune disease.

The peptide symporter SLC15a4 is essential for the development of systemic lupus erythematosus in murine models.

Cryopyrin activates the inflammasome in response to toxins and ATP.

Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation.

IgE<sup>+</sup> memory B cells and plasma cells generated through a germinal-center pathway.

Specification of type 2 innate lymphocytes by the transcriptional determinant Gfi1.

Reply to "On the differentiation of mouse IgE<sup>+</sup> cells".

IgE<sup>+</sup> memory B cells and plasma cells generated through a germinal-center pathway.

TACI-ligand interactions are required for T cell activation and collagen-induced arthritis in mice.

Tumor suppressor BAP1 is essential for thymic development and proliferative responses of T lymphocytes.

Potassium channels Kv1.3 and KCa3.1 cooperatively and compensatorily regulate antigen-specific memory T cell functions.

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf.

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome.

IL-22R Ligands IL-20, IL-22, and IL-24 Promote Wound Healing in Diabetic db/db Mice.

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.

Interleukin-22 alleviates metabolic disorders and restores mucosal immunity in diabetes.

Non-canonical inflammasome activation targets caspase-11.

Dual B Cell Immunotherapy Is Superior to Individual Anti-CD20 Depletion or BAFF Blockade in Murine Models of Spontaneous or Accelerated Lupus.

Preclinical pharmacokinetics, pharmacodynamics, and activity of a humanized anti-CD40 antibody (SGN-40) in rodents and non-human primates.

Publisher Correction: Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy.

Steroid-induced fibroblast growth factors drive an epithelial-mesenchymal inflammatory axis in severe asthma.

In vivo antigen-driven plasmablast enrichment in combination with antigen-specific cell sorting to facilitate the isolation of rare monoclonal antibodies from human B cells.

The tumor suppressor BAP1 cooperates with BRAFV600E to promote tumor formation in cutaneous melanoma.

Specific Btk inhibition suppresses B cell- and myeloid cell-mediated arthritis.