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Extended Multicomponent Reactions with Indole Aldehydes: Access to Unprecedented Polyheterocyclic Scaffolds, Ligands of the Aryl Hydrocarbon Receptor.
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- Angewandte Chemie, 2021, v. 133, n. 5, p. 2635, doi. 10.1002/ange.202011253
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- Article
Moderne Strategien zur Synthese funktioneller Fluorophore.
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- Angewandte Chemie, 2017, v. 129, n. 14, p. 3812, doi. 10.1002/ange.201609394
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- Article
Insertion of Isocyanides into N−Si Bonds: Multicomponent Reactions with Azines Leading to Potent Antiparasitic Compounds.
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- Angewandte Chemie, 2016, v. 128, n. 31, p. 9140, doi. 10.1002/ange.201604109
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- Article
Modern Synthetic Avenues for the Preparation of Functional Fluorophores.
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- Angewandte Chemie International Edition, 2017, v. 56, n. 14, p. 3758, doi. 10.1002/anie.201609394
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- Article
Insertion of Isocyanides into N−Si Bonds: Multicomponent Reactions with Azines Leading to Potent Antiparasitic Compounds.
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- Angewandte Chemie International Edition, 2016, v. 55, n. 31, p. 8994, doi. 10.1002/anie.201604109
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- Article
A Trifluorinated Thiazoline Scaffold Leading to Pro-apoptotic Agents Targeting Prohibitins.
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- Angewandte Chemie International Edition, 2014, v. 53, n. 38, p. 10150, doi. 10.1002/anie.201405758
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- Article
The Prohibitin-Binding Compound Fluorizoline Activates the Integrated Stress Response through the eIF2α Kinase HRI.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 9, p. 8064, doi. 10.3390/ijms24098064
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- Article
Activation of the Integrated Stress Response and ER Stress Protect from Fluorizoline-Induced Apoptosis in HEK293T and U2OS Cell Lines.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 11, p. 6117, doi. 10.3390/ijms22116117
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- Article
Efficient AntiMycolata Agents by Increasing the Lipophilicity of Known Antibiotics through Multicomponent Reactions.
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- Antibiotics (2079-6382), 2023, v. 12, n. 1, p. 83, doi. 10.3390/antibiotics12010083
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- Article
New Trimethoprim-Like Molecules: Bacteriological Evaluation and Insights into Their Action.
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- Antibiotics (2079-6382), 2021, v. 10, n. 6, p. 709, doi. 10.3390/antibiotics10060709
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- Article
A Trifluorinated Thiazoline Scaffold Leading to Pro-apoptotic Agents Targeting Prohibitins.
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- Angewandte Chemie, 2014, v. 126, n. 38, p. 10314, doi. 10.1002/ange.201405758
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- Publication type:
- Article
Exploration of Forbidden Povarov Processes as a Source of Unexpected Reactivity: A Multicomponent Mannich-Ritter Transformation.
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- Angewandte Chemie, 2012, v. 124, n. 28, p. 6980, doi. 10.1002/ange.201202927
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- Publication type:
- Article
Enhanced antimicrobial activity of a peptide derived from human lysozyme by arylation of its tryptophan residues.
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- Journal of Peptide Science, 2016, v. 22, n. 2, p. 123, doi. 10.1002/psc.2850
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- Article
NOXA upregulation by the prohibitin‐binding compound fluorizoline is transcriptionally regulated by integrated stress response‐induced ATF3 and ATF4.
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- FEBS Journal, 2021, v. 288, n. 4, p. 1271, doi. 10.1111/febs.15480
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- Article
Multiple Multicomponent Reactions: Unexplored Substrates, Selective Processes, and Versatile Chemotypes in Biomedicine.
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- Chemistry - A European Journal, 2018, v. 24, n. 54, p. 14513, doi. 10.1002/chem.201802877
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- Article
Constrained Cyclopeptides: Biaryl Formation through Pd-Catalyzed C−H Activation in Peptides-Structural Control of the Cyclization vs. Cyclodimerization Outcome.
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- Chemistry - A European Journal, 2016, v. 22, n. 37, p. 13114, doi. 10.1002/chem.201601832
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- Article
Charting the Chemical Reaction Space around a Multicomponent Combination: Controlled Access to a Diverse Set of Biologically Relevant Scaffolds.
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- Angewandte Chemie, 2023, v. 135, n. 41, p. 1, doi. 10.1002/ange.202303889
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- Article
A Bivalent Activatable Fluorescent Probe for Screening and Intravital Imaging of Chemotherapy‐Induced Cancer Cell Death.
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- Angewandte Chemie, 2022, v. 134, n. 5, p. 1, doi. 10.1002/ange.202113020
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- Article
Spacer-free BODIPY fluorogens in antimicrobial peptides for direct imaging of fungal infection in human tissue.
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- Nature Communications, 2016, v. 7, n. 3, p. 10940, doi. 10.1038/ncomms10940
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- Article
New peptide architectures through C-H activation stapling between tryptophan-phenylalanine/tyrosine residues.
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- Nature Communications, 2015, v. 6, n. 5, p. 7160, doi. 10.1038/ncomms8160
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- Article
Charting the Chemical Reaction Space around a Multicomponent Combination: Controlled Access to a Diverse Set of Biologically Relevant Scaffolds.
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- Angewandte Chemie International Edition, 2023, v. 62, n. 41, p. 1, doi. 10.1002/anie.202303889
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- Publication type:
- Article
A Bivalent Activatable Fluorescent Probe for Screening and Intravital Imaging of Chemotherapy‐Induced Cancer Cell Death.
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- Angewandte Chemie International Edition, 2022, v. 61, n. 5, p. 1, doi. 10.1002/anie.202113020
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- Publication type:
- Article
Extended Multicomponent Reactions with Indole Aldehydes: Access to Unprecedented Polyheterocyclic Scaffolds, Ligands of the Aryl Hydrocarbon Receptor.
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- Angewandte Chemie International Edition, 2021, v. 60, n. 5, p. 2603, doi. 10.1002/anie.202011253
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- Article
Postsynthetic Modification of Peptides: Chemoselective C-Arylation of Tryptophan Residues.
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- Chemistry - A European Journal, 2010, v. 16, n. 4, p. 1124, doi. 10.1002/chem.200902676
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- Article
Heterocycles as Key Substrates in Multicomponent Reactions: The Fast Lane towards Molecular Complexity.
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- Chemistry - A European Journal, 2008, v. 14, n. 28, p. 8444, doi. 10.1002/chem.200800473
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- Article
Straightforward Access to a Structurally Diverse Set of Oxacyclic Scaffolds through a Four-Component Reaction.
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- Angewandte Chemie, 2005, v. 117, n. 40, p. 6679, doi. 10.1002/ange.200501548
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- Article
Identification and Characterization of Sterol Acyltransferases Responsible for Steryl Ester Biosynthesis in Tomato.
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- Frontiers in Plant Science, 2018, p. 1, doi. 10.3389/fpls.2018.00588
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- Article
Modular Access to Tetrasubstituted Imidazolium Salts through Acid-Catalyzed Addition of Isocyanides to Propargylamines.
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- European Journal of Organic Chemistry, 2015, v. 2015, n. 20, p. 4383, doi. 10.1002/ejoc.201500502
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- Article
Introduction of Heteroatom-Based Substituents into 1, 4-Dihydropyridines by Means of a Halogen-Mediated, Oxidative Protocol: Diamination, Sulfonylation, Sulfinylation, Bis-Sulfanylation, and Halo-Phosphonylation Processes.
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- Chemistry - A European Journal, 2000, v. 6, n. 10, p. 1763, doi. 10.1002/(SICI)1521-3765(20000515)6:10<1763::AID-CHEM1763>3.0.CO;2-R
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- Article
Synthesis, pharmacological evaluation and molecular docking of pyranopyrazole-linked 1,4-dihydropyridines as potent positive inotropes.
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- Molecular Diversity, 2017, v. 21, n. 3, p. 533, doi. 10.1007/s11030-017-9738-7
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- Article
Dihydropyridines in MCRs. Tandem processes leading to modular tetrahydroquinoline systems with up to 6 diversity elements.
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- Molecular Diversity, 2003, v. 6, n. 3/4, p. 171, doi. 10.1023/B:MODI.0000006756.83821.80
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- Article
Heterocycle-Based Multicomponent Reactions in Drug Discovery: From Hit Finding to Rational Design.
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- Biomedicines, 2022, v. 10, n. 7, p. N.PAG, doi. 10.3390/biomedicines10071488
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- Article
Double Insertion of Isocyanides into Dihydropyridines: Direct Access to Substituted Benzimidazolium Salts.
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- Angewandte Chemie International Edition, 2007, v. 46, n. 17, p. 3043, doi. 10.1002/anie.200605070
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- Article
Straightforward Access to a Structurally Diverse Set of Oxacyclic Scaffolds through a Four-Component ReactionThis work was supported by DGICYT (Spain, project BQU 2003-00089) and Almirall-Prodesfarma (Barcelona). We also thank Inés Carranco, Prof. F. Albericio, Dr. Miriam Royo, and Marc Vendrell for their assistance with syntheses and analyses.
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- Angewandte Chemie International Edition, 2005, v. 44, n. 40, p. 6521, doi. 10.1002/anie.200501548
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- Article
Reaction Space Charting as a Tool in Organic Chemistry Research and Development.
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- Advanced Synthesis & Catalysis, 2024, v. 366, n. 4, p. 551, doi. 10.1002/adsc.202301205
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- Article
Scope and Post-Transformations for the Borane-Isocyanide Multicomponent Reactions: Concise Access to Structurally Diverse Heterocyclic Compounds.
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- Advanced Synthesis & Catalysis, 2013, v. 355, n. 16, p. 3273, doi. 10.1002/adsc.201300666
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- Article
Fluorizoline-induced apoptosis requires prohibitins in nematodes and human cells.
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- Apoptosis, 2021, v. 26, n. 1/2, p. 83, doi. 10.1007/s10495-020-01651-z
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- Article
Tetrasubstituted Imidazolium Salts as Potent Antiparasitic Agents against African and American Trypanosomiases.
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- Molecules, 2018, v. 23, n. 1, p. 177, doi. 10.3390/molecules23010177
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- Article
Preparation of a Trp-BODIPY fluorogenic amino acid to label peptides for enhanced live-cell fluorescence imaging.
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- Nature Protocols, 2017, v. 12, n. 8, p. 1588, doi. 10.1038/nprot.2017.048
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- Article
Indoloquinolizidine-Peptide Hybrids as Multiple Agonists for D<sub>1</sub> and D<sub>2</sub> Dopamine Receptors.
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- ChemMedChem, 2009, v. 4, n. 9, p. 1514, doi. 10.1002/cmdc.200900149
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- Article
Benzimidazolium Salts as Small, Nonpeptidic and BBB-Permeable Human Prolyl Oligopeptidase Inhibitors.
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- ChemMedChem, 2008, v. 3, n. 10, p. 1558, doi. 10.1002/cmdc.200800152
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- Article
Evolution of a Multicomponent System: Computational and Mechanistic Studies on the Chemo- and Stereoselectivity of a Divergent Process.
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- Chemistry - A European Journal, 2013, v. 19, n. 40, p. 13355, doi. 10.1002/chem.201302072
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- Article
Corrigendum: Boron-Based Dipolar Multicomponent Reactions: Simple Generation of Substituted Aziridines, Oxazolidines and Pyrrolidines.
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- Chemistry - A European Journal, 2011, v. 17, n. 45, p. 12537, doi. 10.1002/chem.201190229
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- Article
Boron-Based Dipolar Multicomponent Reactions: Simple Generation of Substituted Aziridines, Oxazolidines and Pyrrolidines.
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- Chemistry - A European Journal, 2010, v. 16, n. 26, p. 7904, doi. 10.1002/chem.201000349
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- Publication type:
- Article
A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis.
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- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17772-7
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- Publication type:
- Article
Exploration of Forbidden Povarov Processes as a Source of Unexpected Reactivity: A Multicomponent Mannich-Ritter Transformation.
- Published in:
- Angewandte Chemie International Edition, 2012, v. 51, n. 28, p. 6874, doi. 10.1002/anie.201202927
- By:
- Publication type:
- Article