Found: 79
Select item for more details and to access through your institution.
CFTR reduces the proliferation of lung adenocarcinoma and is a strong predictor of survival in both smokers and non-smokers.
- Published in:
- Journal of Cancer Research & Clinical Oncology, 2022, v. 148, n. 12, p. 3293, doi. 10.1007/s00432-022-04106-x
- By:
- Publication type:
- Article
Robust and Seamless Integration of Thiol‐Ene‐Epoxy Thermosets with Thermoplastics and Glass as Hybrid Microfluidic Devices Suitable for Drug Studies.
- Published in:
- Advanced Materials Interfaces, 2024, v. 11, n. 14, p. 1, doi. 10.1002/admi.202300972
- By:
- Publication type:
- Article
CYP2C19 and CYP2D6 Genotypes and Metabolizer Status Distribution in a Bulgarian Psychiatric Cohort.
- Published in:
- Journal of Personalized Medicine, 2022, v. 12, n. 7, p. 1187, doi. 10.3390/jpm12071187
- By:
- Publication type:
- Article
Editorial: Population Pharmacogenomics (PGx): From Variant Identification to Clinical Implementation.
- Published in:
- 2021
- By:
- Publication type:
- Editorial
Genetic Variant ABCC1 rs45511401 Is Associated with Increased Response to Statins in Patients with Familial Hypercholesterolemia.
- Published in:
- Pharmaceutics, 2022, v. 14, n. 5, p. 944, doi. 10.3390/pharmaceutics14050944
- By:
- Publication type:
- Article
Human soluble ACE2 improves the effect of remdesivir in SARS‐CoV‐2 infection.
- Published in:
- EMBO Molecular Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.15252/emmm.202013426
- By:
- Publication type:
- Article
Mechanism of baricitinib supports artificial intelligence‐predicted testing in COVID‐19 patients.
- Published in:
- EMBO Molecular Medicine, 2020, v. 12, n. 8, p. 1, doi. 10.15252/emmm.202012697
- By:
- Publication type:
- Article
The Importance of Patient-Specific Factors for Hepatic Drug Response and Toxicity.
- Published in:
- International Journal of Molecular Sciences, 2016, v. 17, n. 10, p. 1714, doi. 10.3390/ijms17101714
- By:
- Publication type:
- Article
Meta-analysis of the global distribution of clinically relevant CYP2C8 alleles and their inferred functional consequences.
- Published in:
- Human Genomics, 2024, v. 18, n. 1, p. 1, doi. 10.1186/s40246-024-00610-y
- By:
- Publication type:
- Article
Emerging trends in pharmacogenomics: from common variant associations toward comprehensive genomic profiling.
- Published in:
- 2023
- By:
- Publication type:
- Editorial
Two different isoforms of osteopontin modulate myelination and axonal integrity.
- Published in:
- FASEB Bioadvances, 2023, v. 5, n. 8, p. 336, doi. 10.1096/fba.2023-00030
- By:
- Publication type:
- Article
Population pharmacogenomics: an update on ethnogeographic differences and opportunities for precision public health.
- Published in:
- Human Genetics, 2022, v. 141, n. 6, p. 1113, doi. 10.1007/s00439-021-02385-x
- By:
- Publication type:
- Article
Genetic and Epigenetic Biomarkers of Immune Checkpoint Blockade Response.
- Published in:
- Journal of Clinical Medicine, 2020, v. 9, n. 1, p. 286, doi. 10.3390/jcm9010286
- By:
- Publication type:
- Article
Single base resolution analysis of 5-hydroxymethylcytosine in 188 human genes: implications for hepatic gene expression.
- Published in:
- Nucleic Acids Research, 2016, v. 44, n. 14, p. 6756, doi. 10.1093/nar/gkw316
- By:
- Publication type:
- Article
Magnesium enhances cardiomyocyte proliferation and suppresses cardiac fibrosis induced by chronic ACTH exposure in rats.
- Published in:
- Magnesium Research, 2021, v. 34, n. 2, p. 74, doi. 10.1684/mrh.2021.0484
- By:
- Publication type:
- Article
Macrophage‐derived insulin antagonist ImpL2 induces lipoprotein mobilization upon bacterial infection.
- Published in:
- EMBO Journal, 2023, v. 42, n. 23, p. 1, doi. 10.15252/embj.2023114086
- By:
- Publication type:
- Article
Adjudin improves beta cell maturation, hepatic glucose uptake and glucose homeostasis.
- Published in:
- Diabetologia, 2024, v. 67, n. 1, p. 137, doi. 10.1007/s00125-023-06020-4
- By:
- Publication type:
- Article
Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease.
- Published in:
- Scientific Reports, 2016, p. 25187, doi. 10.1038/srep25187
- By:
- Publication type:
- Article
Intraocular liver spheroids for non-invasive high-resolution in vivo monitoring of liver cell function.
- Published in:
- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45122-4
- By:
- Publication type:
- Article
GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41893-4
- By:
- Publication type:
- Article
Multi-Well Array Culture of Primary Human Hepatocyte Spheroids for Clearance Extrapolation of Slowly Metabolized Compounds.
- Published in:
- AAPS Journal, 2022, v. 24, n. 2, p. 1, doi. 10.1208/s12248-022-00689-y
- By:
- Publication type:
- Article
Pharmacogenomic Biomarkers for Improved Drug Therapy-Recent Progress and Future Developments.
- Published in:
- AAPS Journal, 2018, v. 20, n. 1, p. 1, doi. 10.1208/s12248-017-0161-x
- By:
- Publication type:
- Article
TACRINE-SQUARAMIDE DERIVATIVES AS POTENT CHOLINESTERASE INHIBITORS.
- Published in:
- 2022
- By:
- Publication type:
- Abstract
ORGANOTYPIC AND MICROPHYSIOLOGICAL HUMAN TISSUE MODELS FOR TRANSLATIONAL TOXICOLOGY AND PHARMACOLOGY.
- Published in:
- 2022
- By:
- Publication type:
- Abstract
Ethnogeographic and inter-individual variability of human ABC transporters.
- Published in:
- Human Genetics, 2020, v. 139, n. 5, p. 623, doi. 10.1007/s00439-020-02150-6
- By:
- Publication type:
- Article
The genetic landscape of the human solute carrier (SLC) transporter superfamily.
- Published in:
- Human Genetics, 2019, v. 138, n. 11/12, p. 1359, doi. 10.1007/s00439-019-02081-x
- By:
- Publication type:
- Article
Structural variation of the coding and non-coding human pharmacogenome.
- Published in:
- NPJ Genomic Medicine, 2023, v. 8, n. 1, p. 1, doi. 10.1038/s41525-023-00371-y
- By:
- Publication type:
- Article
The prevalence, genetic complexity and population-specific founder effects of human autosomal recessive disorders.
- Published in:
- NPJ Genomic Medicine, 2021, v. 6, n. 1, p. 1, doi. 10.1038/s41525-021-00203-x
- By:
- Publication type:
- Article
Emerging strategies to bridge the gap between pharmacogenomic research and its clinical implementation.
- Published in:
- NPJ Genomic Medicine, 2020, v. 5, n. 1, p. 1, doi. 10.1038/s41525-020-0119-2
- By:
- Publication type:
- Article
OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids.
- Published in:
- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-67192-6
- By:
- Publication type:
- Article
Comprehensive Evaluation of Organotypic and Microphysiological Liver Models for Prediction of Drug-Induced Liver Injury.
- Published in:
- Frontiers in Pharmacology, 2019, p. 1, doi. 10.3389/fphar.2019.01093
- By:
- Publication type:
- Article
Consequences of Amyloid‐β Deficiency for the Liver.
- Published in:
- Advanced Science, 2024, v. 11, n. 18, p. 1, doi. 10.1002/advs.202307734
- By:
- Publication type:
- Article
Bioengineered Pancreas–Liver Crosstalk in a Microfluidic Coculture Chip Identifies Human Metabolic Response Signatures in Prediabetic Hyperglycemia.
- Published in:
- Advanced Science, 2022, v. 9, n. 34, p. 1, doi. 10.1002/advs.202203368
- By:
- Publication type:
- Article
3D Adipose Tissue Culture Links the Organotypic Microenvironment to Improved Adipogenesis.
- Published in:
- Advanced Science, 2021, v. 8, n. 16, p. 1, doi. 10.1002/advs.202100106
- By:
- Publication type:
- Article
3D Adipose Tissue Culture Links the Organotypic Microenvironment to Improved Adipogenesis.
- Published in:
- Advanced Science, 2021, v. 8, n. 16, p. 1, doi. 10.1002/advs.202100106
- By:
- Publication type:
- Article
A 3D Cell Culture Model Identifies Wnt/β‐Catenin Mediated Inhibition of p53 as a Critical Step during Human Hepatocyte Regeneration.
- Published in:
- Advanced Science, 2020, v. 7, n. 15, p. 1, doi. 10.1002/advs.202000248
- By:
- Publication type:
- Article
Insulin-dependent glucose consumption dynamics in 3D primary human liver cultures measured by a sensitive and specific glucose sensor with nanoliter input volume.
- Published in:
- FASEB Journal, 2021, v. 35, n. 3, p. 1, doi. 10.1096/fj.202001989RR
- By:
- Publication type:
- Article
Expression of SUMO enzymes is fiber type dependent in skeletal muscles and is dysregulated in muscle disuse.
- Published in:
- FASEB Journal, 2020, v. 34, n. 2, p. 2269, doi. 10.1096/fj.201901913R
- By:
- Publication type:
- Article
Endogenous and xenobiotic metabolic stability of primary human hepatocytes in long-term 3D spheroid cultures revealed by a combination of targeted and untargeted metabolomics.
- Published in:
- FASEB Journal, 2017, v. 31, n. 6, p. 2696, doi. 10.1096/fj.201601375R
- By:
- Publication type:
- Article
An overlooked subset of Cx3cr1<sup>wt/wt</sup> microglia in the Cx3cr1<sup>CreER-Eyfp/wt</sup> mouse has a repopulation advantage over Cx3cr1<sup>CreER-Eyfp/wt</sup> microglia following microglial depletion.
- Published in:
- 2022
- By:
- Publication type:
- journal article
Estrogen receptor activation remodels TEAD1 gene expression to alleviate hepatic steatosis.
- Published in:
- Molecular Systems Biology, 2024, v. 20, n. 4, p. 374, doi. 10.1038/s44320-024-00024-x
- By:
- Publication type:
- Article
Rewiring of catecholamine‐induced calcium signalling is an early event in non‐alcoholic fatty liver disease.
- Published in:
- Journal of Physiology, 2023, v. 601, n. 8, p. 1317, doi. 10.1113/JP284526
- By:
- Publication type:
- Article
Liver macrophages inhibit the endogenous antioxidant response in obesity-associated insulin resistance.
- Published in:
- Science Translational Medicine, 2020, v. 12, n. 532, p. 1, doi. 10.1126/scitranslmed.aaw9709
- By:
- Publication type:
- Article
Cardiovascular Pharmacogenomics: An Update on Clinical Studies of Antithrombotic Drugs in Brazilian Patients.
- Published in:
- Molecular Diagnosis & Therapy, 2021, v. 25, n. 6, p. 735, doi. 10.1007/s40291-021-00549-z
- By:
- Publication type:
- Article
PharmVar GeneFocus: CYP3A5.
- Published in:
- Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1159, doi. 10.1002/cpt.2563
- By:
- Publication type:
- Article
Computational Tools to Assess the Functional Consequences of Rare and Noncoding Pharmacogenetic Variability.
- Published in:
- Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 3, p. 626, doi. 10.1002/cpt.2289
- By:
- Publication type:
- Article
PharmVar GeneFocus: CYP2B6.
- Published in:
- Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 1, p. 82, doi. 10.1002/cpt.2166
- By:
- Publication type:
- Article
Global Frequencies of Clinically Important HLA Alleles and Their Implications For the Cost‐Effectiveness of Preemptive Pharmacogenetic Testing.
- Published in:
- Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 1, p. 160, doi. 10.1002/cpt.1944
- By:
- Publication type:
- Article
Clinically Relevant Cytochrome P450 3A4 Induction Mechanisms and Drug Screening in Three‐Dimensional Spheroid Cultures of Primary Human Hepatocytes.
- Published in:
- Clinical Pharmacology & Therapeutics, 2020, v. 108, n. 4, p. 844, doi. 10.1002/cpt.1860
- By:
- Publication type:
- Article
Development of the PGx‐Passport: A Panel of Actionable Germline Genetic Variants for Pre‐Emptive Pharmacogenetic Testing.
- Published in:
- Clinical Pharmacology & Therapeutics, 2019, v. 106, n. 4, p. 866, doi. 10.1002/cpt.1489
- By:
- Publication type:
- Article