Found: 20
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GPCR heterodimers: asymmetries in ligand binding and signalling output offer new targets for drug discovery.
- Published in:
- 2013
- By:
- Publication type:
- journal article
Molecular insights into intrinsic transducer-coupling bias in the CXCR4-CXCR7 system.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40482-9
- By:
- Publication type:
- Article
Dynamic spatiotemporal determinants modulate GPCR:G protein coupling selectivity and promiscuity.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34055-5
- By:
- Publication type:
- Article
Unraveling allostery within the angiotensin II type 1 receptor for Gα<sub>q</sub> and β-arrestin coupling.
- Published in:
- Science Signaling, 2023, v. 16, n. 797, p. 1, doi. 10.1126/scisignal.adf2173
- By:
- Publication type:
- Article
Phosphoinositide 3-kinase regulates Β2-adrenergic receptor endocytosis by AP-2 recruitment to the receptor/Β-arrestin complex.
- Published in:
- Journal of Cell Biology, 2002, v. 158, n. 3, p. 563, doi. 10.1083/jcb.200202113
- By:
- Publication type:
- Article
A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling.
- Published in:
- Nature Communications, 2017, v. 8, n. 4, p. 15054, doi. 10.1038/ncomms15054
- By:
- Publication type:
- Article
Monitoring G protein-coupled receptor and β-arrestin trafficking in live cells using enhanced bystander BRET.
- Published in:
- Nature Communications, 2016, v. 7, n. 7, p. 12178, doi. 10.1038/ncomms12178
- By:
- Publication type:
- Article
Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensors.
- Published in:
- Science Signaling, 2018, v. 11, n. 559, p. 1, doi. 10.1126/scisignal.aat1631
- By:
- Publication type:
- Article
FZD<sub>5</sub> is a Gαq-coupled receptor that exhibits the functional hallmarks of prototypical GPCRs.
- Published in:
- Science Signaling, 2018, v. 11, n. 559, p. 1, doi. 10.1126/scisignal.aar5536
- By:
- Publication type:
- Article
Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9.
- Published in:
- Science Signaling, 2018, v. 11, n. 549, p. 1, doi. 10.1126/scisignal.aat7650
- By:
- Publication type:
- Article
Signal profiling of the β1AR reveals coupling to novel signalling pathways and distinct phenotypic responses mediated by β1AR and β2AR.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-65636-3
- By:
- Publication type:
- Article
Discovery of a dual Ras and ARF6 inhibitor from a GPCR endocytosis screen.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24968-y
- By:
- Publication type:
- Article
Cross-Talk between Signaling Pathways Can Generate Robust Oscillations in Calcium and cAMP.
- Published in:
- PLoS ONE, 2009, v. 4, n. 10, p. 1, doi. 10.1371/journal.pone.0007189
- By:
- Publication type:
- Article
Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32386-x
- By:
- Publication type:
- Article
The G protein-coupled receptor kinase-2 is a TGFβ-inducible antagonist of TGFβ signal transduction.
- Published in:
- EMBO Journal, 2005, v. 24, n. 18, p. 3247, doi. 10.1038/sj.emboj.7600794
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- Publication type:
- Article
Key phosphorylation sites in GPCRs orchestrate the contribution of β‐Arrestin 1 in ERK1/2 activation.
- Published in:
- EMBO Reports, 2020, v. 21, n. 9, p. 1, doi. 10.15252/embr.201949886
- By:
- Publication type:
- Article
Allosteric and biased G protein-coupled receptor signaling regulation: potentials for new therapeutics.
- Published in:
- Frontiers in Endocrinology, 2014, v. 5, p. 1, doi. 10.3389/fendo.2014.00068
- By:
- Publication type:
- Article
Allosteric and biased G protein-coupled receptor signaling regulation: Potentials for new therapeutics.
- Published in:
- Frontiers in Endocrinology, 2014, v. 5, p. 1, doi. 10.3389/fendo.2014.00068
- By:
- Publication type:
- Article
Differential b-Arrestin-Dependent Conformational Signaling and Cellular Responses Revealed by Angiotensin Analogs.
- Published in:
- Science Signaling, 2012, v. 5, n. 221, p. 1, doi. 10.1126/scisignal.200252
- By:
- Publication type:
- Article
Synthesis of azabicycloalkanone amino acid and azapeptide mimics and their application as modulators of the prostaglandin F2α receptor for delaying preterm birth.
- Published in:
- Canadian Journal of Chemistry, 2014, v. 92, n. 11, p. 1031, doi. 10.1139/cjc-2014-0289
- By:
- Publication type:
- Article