Found: 17
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Caspase-6 does not contribute to the proteolysis of mutant huntingtin in the HdhQ150 knock-in mouse model of Huntington's disease.
- Published in:
- PLoS Currents, 2012, p. 81, doi. 10.1371/4fd085bfc9973
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- Publication type:
- Article
Hsp27 overexpression in the R6/2 mouse model of Huntington's disease: chronic neurodegeneration does not induce Hsp27 activation.
- Published in:
- Human Molecular Genetics, 2007, v. 16, n. 9, p. 1078, doi. 10.1093/hmg/ddm057
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- Publication type:
- Article
Contribution of nuclear and extranuclear polyQ to neurological phenotypes in mouse models of Huntington's disease.
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- Human Molecular Genetics, 2005, v. 14, n. 20, p. 3065, doi. 10.1093/hmg/ddi340
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- Article
A CAG repeat threshold for therapeutics targeting somatic instability in Huntington's disease.
- Published in:
- Brain: A Journal of Neurology, 2024, v. 147, n. 5, p. 1784, doi. 10.1093/brain/awae063
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- Article
Alternative processing of human HTT mRNA with implications for Huntington's disease therapeutics.
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- Brain: A Journal of Neurology, 2022, v. 145, n. 12, p. 4409, doi. 10.1093/brain/awac241
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- Article
Correlative light and electron microscopy suggests that mutant huntingtin dysregulates the endolysosomal pathway in presymptomatic Huntington's disease.
- Published in:
- Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01172-z
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- Article
Phenotype onset in Huntington's disease knock‐in mice is correlated with the incomplete splicing of the mutant huntingtin gene.
- Published in:
- Journal of Neuroscience Research, 2019, v. 97, n. 12, p. 1590, doi. 10.1002/jnr.24493
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- Article
P3-377: A novel pathogenic pathway of immune activation detectable before cinical onset in Huntington's disease
- Published in:
- 2008
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- Abstract
HDAC4 Does Not Act as a Protein Deacetylase in the Postnatal Murine Brain <i>In Vivo</i>.
- Published in:
- PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0080849
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- Publication type:
- Article
Natural Selection of Human Embryos: Impaired Decidualization of Endometrium Disables Embryo-Maternal Interactions and Causes Recurrent Pregnancy Loss.
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- PLoS ONE, 2010, v. 5, n. 4, p. 1, doi. 10.1371/journal.pone.0010287
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- Article
Natural Selection of Human Embryos: Decidualizing Endometrial Stromal Cells Serve as Sensors of Embryo Quality upon Implantation.
- Published in:
- PLoS ONE, 2010, v. 5, n. 4, p. 1, doi. 10.1371/journal.pone.0010258
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- Publication type:
- Article
Mutant huntingtin fragmentation in immune cells tracks Huntington's disease progression.
- Published in:
- Journal of Clinical Investigation, 2012, v. 122, n. 10, p. 1, doi. 10.1172/JCI64565
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- Publication type:
- Article
Early detection of exon 1 huntingtin aggregation in zQ175 brains by molecular and histological approaches.
- Published in:
- Brain Communications, 2023, v. 5, n. 1, p. 1, doi. 10.1093/braincomms/fcad010
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- Publication type:
- Article
Deregulation of the serum- and glucocorticoid-inducible kinase SGK1 in the endometrium causes reproductive failure.
- Published in:
- Nature Medicine, 2011, v. 17, n. 11, p. 1509, doi. 10.1038/nm.2498
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- Article
Huntingtin and the molecular pathogenesis of Huntington's disease.
- Published in:
- EMBO Reports, 2004, v. 5, n. 10, p. 958, doi. 10.1038/sj.embor.7400250
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- Publication type:
- Article
HDAC4 Reduction: A Novel Therapeutic Strategy to Target Cytoplasmic Huntingtin and Ameliorate Neurodegeneration.
- Published in:
- PLoS Biology, 2013, v. 11, n. 11, p. 1, doi. 10.1371/journal.pbio.1001717
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- Publication type:
- Article
TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models.
- Published in:
- EMBO Journal, 2020, v. 39, n. 17, p. 1, doi. 10.15252/embj.2020104671
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- Article