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Preliminary safety and efficacy data of brecanavir, a novel HIV-1 protease inhibitor: 24 week data from study HPR10006.
Published in:
Journal of Antimicrobial Chemotherapy (JAC), 2007, v. 60, n. 1, p. 170, doi. 10.1093/jac/dkm122
By:
- Jacob P. Lalezari;
- Douglas J. Ward;
- Susan A. Tomkins;
- Harmony P. Garges
Publication type:
Article
HIV-1 attachment inhibitor prodrug BMS-663068 in antiretroviral-experienced subjects: week 24 sub-group analysis.
Published in:
Journal of the International AIDS Society, 2014, v. 17, p. n/a, doi. 10.7448/IAS.17.4.19529
By:
- Brinson, Cynthia;
- Lalezari, Jacob;
- Gulam, Latiff H;
- Thompson, Melanie;
- Echevarria, Juan;
- Treviño-Pérez, Sandra;
- Stock, David;
- Samit, Joshi R;
- George, Hanna J;
- Lataillade, Max
Publication type:
Article
Safety profile of HIV-1 attachment inhibitor prodrug BMS-663068 in antiretroviral-experienced subjects: week 24 analysis.
Published in:
Journal of the International AIDS Society, 2014, v. 17, p. n/a, doi. 10.7448/IAS.17.4.19530
By:
- Lalezari, Jacob;
- Latiff, Gulam H;
- Brinson, Cynthia;
- Echevarria, Juan;
- Treviño-Pérez, Sandra;
- Bogner, Johannes R;
- Stock, David;
- Joshi, Samit R;
- Hanna, George J;
- Lataillade, Max
Publication type:
Article
Restoration of Blood Total Glutathione Status and Lymphocyte Function Following -Lipoic Acid Supplementation in Patients with HIV Infection.
Published in:
Journal of Alternative & Complementary Medicine, 2008, v. 14, n. 2, p. 139, doi. 10.1089/acm.2006.6397
By:
- Jariwalla, Raxit J.;
- Lalezari, Jacob;
- Cenko, Diane;
- Mansour, Sam E.;
- Kumar, Abha;
- Gangapurkar, Bhakti;
- Nakamura, Daniel
Publication type:
Article
Zalcitabine compared with zidovudine in patients with advanced HIV-1 infection who received previous zidovudine therapy.
Published in:
1993
By:
- Fischl, Margaret A.;
- Olson, Richard M.;
- Follansbee, Stephen E.;
- Lalezari, Jacob P.;
- Henry, David H.;
- Frame, Peter T.;
- Remick, Scot C.;
- Salgo, Miklos P.;
- Lin, Amy H.;
- Nauss-Karol, Cheryl;
- Lieberman, Judith;
- Soo, Whaijen;
- Fischl, M A;
- Olson, R M;
- Follansbee, S E;
- Lalezari, J P;
- Henry, D H;
- Frame, P T;
- Remick, S C;
- Salgo, M P
Publication type:
journal article
Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34<sup>+</sup> cells.
Published in:
Nature Medicine, 2009, v. 15, n. 3, p. 285, doi. 10.1038/nm.1932
By:
- Mitsuyasu, Ronald T.;
- Merigan, Thomas C.;
- Carr, Andrew;
- Zack, Jerome A.;
- Winters, Mark A.;
- Workman, Cassy;
- Bloch, Mark;
- Lalezari, Jacob;
- Becker, Stephen;
- Thornton, Lorna;
- Akil, Bisher;
- Khanlou, Homayoon;
- Finlayson, Robert;
- McFarlane, Robert;
- Smith, Don E.;
- Garsia, Roger;
- Ma, David;
- Law, Matthew;
- Murray, John M.;
- von Kalle, Christof
Publication type:
Article
T-1249 Retains Potent Antiretroviral Activity in Patients Who Had Experienced Virological Failure while on an Enfuvirtide-Containing Treatment Regimen.
Published in:
Journal of Infectious Diseases, 2005, v. 191, n. 7, p. 1155
By:
- Lalezari, Jacob P.;
- Bellos, Nicholaos C.;
- Sathasivam, Kunthavi;
- Richmond, Gary J.;
- Cohen, Calvin J.;
- Myers, Jr., Robert A.;
- Henry, David H.;
- Raskino, Claire;
- Melby, Tom;
- Murchison, Hugh;
- Ying Zhang;
- Spence, Rebecca;
- Greenberg, Michael L.;
- DeMasi, Ralph A.;
- Miralles, G. Diego
Publication type:
Article
Loss of Cytomegalovirus-Specific CD4[sup+] T Cell Responses in Human Immunodeficiency Virus Type 1-Infected Patients with High CD4[sup+] T Cell Counts and Recurrent Retinitis.
Published in:
Journal of Infectious Diseases, 2001, v. 183, n. 8, p. 1285
By:
- Schmidt, Diane K.;
- Viswanathan, Mohan N.;
- McCune, Joseph M.;
- Komanduri, Krishna V.;
- Lalezari, Jacob P.;
- Feinberg, Judith;
- Frame, Ronald D.;
- Hutchins, Robert K.
Publication type:
Article
The Safety and Efficacy of Adefovir Dipivoxil, a Novel Anti-Human Immunodeficiency Virus (HIV) Therapy, in HIV-Infected Adults: A Randomized, Double-Blind, Placebo-Controlled Trial.
Published in:
Journal of Infectious Diseases, 1997, v. 176, n. 6, p. 1517
By:
- Deeks, Steven G.;
- Collier, Ann;
- Lalezari, Jacob;
- Pavia, Andrew;
- Rodrigue, Daniel;
- Drew, W. Lawrence;
- Toole, Jay;
- Jaffe, Howard S.;
- Mulato, Andrew S.;
- Lamy, Patrick D.;
- Li, Weixing;
- Cherrington, Julie M.;
- Hellmann, Nicholas;
- Kahn, James
Publication type:
Article
A Randomized, Double-Blind, Placebo-Controlled Trial of Cidofovir Gel for the Treatment of Acyclovir-Unresponsive Mucocutaneous Herpes Simplex Virus Infection in Patients with AIDS.
Published in:
Journal of Infectious Diseases, 1997, v. 176, n. 4, p. 892
By:
- Lalezari, Jacob;
- Schacker, Tim;
- Feinberg, Judith;
- Gathe, Joseph;
- Lee, Sabina;
- Cheung, Tony;
- Kramer, Francoise;
- Kessler, Harold;
- Corey, Lawrence;
- Drew, W. Lawrence;
- Boggs, John;
- McGuire, Brian;
- Jaffe, Howard S.;
- Safrin, Sharon
Publication type:
Article
Evolution of Mutations Conferring Multidrug Resistance during Prophylaxis and Therapy for Cytomegalovirus Disease.
Published in:
Journal of Infectious Diseases, 1997, v. 176, n. 3, p. 786
By:
- Chou, Sunwen;
- Marousek, Gail;
- Guentzel, Susan;
- Follansbee, Stephen E.;
- Poscher, Margaret E.;
- Lalezari, Jacob P.;
- Miner, Richard C.;
- Drew, W. Lawrence
Publication type:
Article
Antiretroviral Monotherapy in Early Stage Human Immunodeficiency Virus Disease Has No Detectable Effect on Virus Load in Peripheral Blood and Lymph Nodes.
Published in:
Journal of Infectious Diseases, 1996, v. 173, n. 4, p. 849, doi. 10.1093/infdis/173.4.849
By:
- Cohen, Oren J.;
- Pantaleo, Giuseppe;
- Holodniy, Mark;
- Fox, Cecil H.;
- Orenstein, Jan M.;
- Schnittman, Steven;
- Niu, Manette;
- Graziosi, Cecilia;
- Pavlakis, George N.;
- Lalezari, Jacob;
- Bartlett, John A.;
- Steigbigel, Roy T.;
- Cohn, Jonathan;
- Novak, Richard;
- McMahon, Deborah;
- Bilello, John;
- Fauci, Anthony S.
Publication type:
Article
Pharmacokinetic, Safety, and Antiviral Profiles of Oral Ganciclovir in Persons Infected with Human Immunodeficiency Virus: A Phase I/II Study.
Published in:
Journal of Infectious Diseases, 1995, v. 171, n. 6, p. 1431, doi. 10.1093/infdis/171.6.1431
By:
- Spector, Stephen A.;
- Busch, David F.;
- Follansbee, Stephen;
- Squires, Kathryn;
- Lalezari, Jacob P.;
- Jacobson, Mark A.;
- Connor, James D.;
- Jung, Donald;
- Shadman, Anna;
- Mastre, Barbara;
- Buhles, William;
- Drew, W. Lawrence
Publication type:
Article
Treatment With Intravenous (S)-1-[3-Hydroxy-2-(Phosphonylmethoxy)Propyl]-Cytosine Of Acyclovir-Resistant Mucocutaneous Infection With Herpes Simplexvirus In A Patient With Aids.
Published in:
Journal of Infectious Diseases, 1994, v. 170, n. 3, p. 570
By:
- Lalezari, Jacob P.;
- Lawrence Drew, W.;
- Glutzer, Eileen;
- Miner, Dick;
- Safrin, Sharon;
- F. Owen, William;
- Davidson, Jeffrey M.;
- Fisher, Peggy E.;
- Jaffe, Howard S.
Publication type:
Article
Immunogenicity and Safety of 13-Valent Pneumococcal Conjugate Vaccine in HIVInfected Adults Previously Vaccinated With Pneumococcal Polysaccharide Vaccine.
Published in:
Journal of Infectious Diseases, 2015, v. 212, n. 1, p. 18, doi. 10.1093/infdis/jiu631
By:
- Glesby, Marshall J.;
- Watson, Wendy;
- Brinson, Cynthia;
- Greenberg, Richard N.;
- Lalezari, Jacob P.;
- Skiest, Daniel;
- Sundaraiyer, Vani;
- Natuk, Robert;
- Gurtman, Alejandra;
- Scott, Daniel A.;
- Emini, Emilio A.;
- Gruber, William C.;
- Schmoele-Thoma, Beate
Publication type:
Article
Anti-HIV-1 Activity of Weekly or Biweekly Treatment with Subcutaneous PRO 140, a CCR5 Monoclonal Antibody.
Published in:
Journal of Infectious Diseases, 2010, v. 201, n. 10, p. 1481, doi. 10.1086/652190
By:
- Jacobson, Jeffrey M.;
- Thompson, Melanie A.;
- Lalezari, Jacob P.;
- Saag, Michael S.;
- Zingman, Barry S.;
- D'Ambrosio, Paul;
- Stambler, Nancy;
- Rotshteyn, Yakov;
- Marozsan, Andre J.;
- Maddon, Paul J.;
- Morris, Stephen A.;
- Olson, William C.
Publication type:
Article
Safety, Pharmacokinetics, and Antiviral Activity of HGSOO4, a Novel Fully Human IgG4 Monoclonal Antibody against CCR5, in H1V-1—Infected Patients.
Published in:
Journal of Infectious Diseases, 2008, v. 197, n. 5, p. 721, doi. 10.1086/527327
By:
- Lalezari, Jacob;
- Yadavalli, Gopal K.;
- Para, Michael;
- Richmond, Gary;
- DeJesus, Edwin;
- Brown, Stephen J.;
- Cai, Wendy;
- Chen, Cecil;
- Zhong, John;
- Novello, Lu Anne;
- Lederman, Michael M.;
- Subramanian, G. Mani
Publication type:
Article
Assessment of Drug-drug Interaction Potential of Enfuvirtide in Human Immunodeficiency Virus Type 1-infected Patients<sup>*</sup>.
Published in:
Clinical Pharmacology & Therapeutics, 2004, v. 75, n. 6, p. 558, doi. 10.1016/j.clpt.2004.02.003
By:
- Zhang, Xiaoping;
- Lalezari, Jacob P.;
- Badley, Andrew D.;
- Dorr, Albert;
- Kolis, Stanley J.;
- Kinchelow, Tosca;
- Patel, Indravadan H.
Publication type:
Article
Assessment of Metabolic Inhibition Potential of Enfuvirtide Using a 5-Drug Cocktail in HIV-1 Infected Patients.
Published in:
Clinical Pharmacology & Therapeutics, 2003, v. 73, n. 2, p. P81, doi. 10.1016/S0009-9236(03)90658-8
By:
- Zhang, Xiaoping;
- Patel, Indravadan H.;
- Lalezari, Jacob;
- Badley, Andrew;
- Hawker, Nina;
- Dorr, Albert;
- Kolis, Stanley J.;
- Kinchelow, Tosca
Publication type:
Article
On-treatment HCV RNA as a predictor of sustained virological response in HCV genotype 3-infected patients treated with daclatasvir and sofosbuvir.
Published in:
Liver International, 2016, v. 36, n. 11, p. 1611, doi. 10.1111/liv.13165
By:
- Kowdley, Kris V.;
- Nelson, David R.;
- Lalezari, Jacob P.;
- Box, Terry;
- Gitlin, Norman;
- Poleynard, Gary;
- Rabinovitz, Mordechai;
- Ravendhran, Natarajan;
- Sheikh, Aasim M.;
- Siddique, Asma;
- Bhore, Rafia;
- Noviello, Stephanie;
- Rana, Khurram
Publication type:
Article
Maraviroc.
Published in:
2007
By:
- Lalezari, Jacob
Publication type:
Editorial
Enfuvirtide: A Viewpoint by Jacob Lalezari.
Published in:
Drugs, 2003, v. 63, n. 24, p. 2767, doi. 10.2165/00003495-200363240-00007
By:
- Lalezari, Jacob
Publication type:
Article
Intravenous cidofovir for peripheral cytomegalovirus retinitis in patients with AIDS.
Published in:
Annals of Internal Medicine, 1997, v. 126, n. 4, p. 257, doi. 10.7326/0003-4819-126-4-199702150-00001
By:
- Lalezari, Jacob P.;
- Stagg, Robert J.
Publication type:
Article
TORO: Ninety-Six-Week Virologic and Immunologic Response and Safety Evaluation of Enfuvirtide with an Optimized Background of Antiretrovirals.
Published in:
AIDS Patient Care & STDs, 2007, v. 21, n. 8, p. 533, doi. 10.1089/apc.2006.0174
By:
- Reynes, Jacques;
- Arastéh, Keikawus;
- Clotet, Bonaventura;
- Cohen, Calvin;
- Cooper, David A.;
- Delfraissy, Jean-François;
- Eron Jr., Joseph J.;
- Henry, Keith;
- Katlama, Christine;
- Kuritzkes, Daniel R.;
- Lalezari, Jacob P.;
- Lange, Joep;
- Lazzarin, Adriano;
- Montaner, Julio S. G.;
- Nelson, Mark;
- O' Hearn, Mary;
- Stellbrink, Hans-Jürgen;
- Trottier, Benoit;
- Walmsley, Sharon L.;
- Buss, Neil E.
Publication type:
Article
EDP-514 in healthy subjects and nucleos(t)ide reverse transcriptase inhibitor-suppressed patients with chronic hepatitis B.
Published in:
Antiviral Therapy, 2022, v. 27, n. 6, p. 1, doi. 10.1177/13596535221127848
By:
- Feld, Jordan J;
- Lawitz, Eric;
- Nguyen, Tuan;
- Lalezari, Jacob;
- Hassanein, Tarek;
- Martin, Paul;
- Han, Steven-Huy;
- Dieterich, Douglas;
- Giard, Jeanne-Marie;
- De La Rosa, Guy;
- Ahmad, Alaa;
- Luo, Ed;
- Conery, Annie L;
- Adda, Nathalie
Publication type:
Article
Histone Deacetylase Inhibitor Romidepsin Induces HIV Expression in CD4 T Cells from Patients on Suppressive Antiretroviral Therapy at Concentrations Achieved by Clinical Dosing.
Published in:
PLoS Pathogens, 2014, v. 10, n. 4, p. 1, doi. 10.1371/journal.ppat.1004071
By:
- Wei, Datsen George;
- Chiang, Vicki;
- Fyne, Elizabeth;
- Balakrishnan, Mini;
- Barnes, Tiffany;
- Graupe, Michael;
- Hesselgesser, Joseph;
- Irrinki, Alivelu;
- Murry, Jeffrey P.;
- Stepan, George;
- Stray, Kirsten M.;
- Tsai, Angela;
- Yu, Helen;
- Spindler, Jonathan;
- Kearney, Mary;
- Spina, Celsa A.;
- McMahon, Deborah;
- Lalezari, Jacob;
- Sloan, Derek;
- Mellors, John
Publication type:
Article
Daclatasvir in Combination With Asunaprevir and Beclabuvir for Hepatitis C Virus Genotype 1 Infection With Compensated Cirrhosis.
Published in:
JAMA: Journal of the American Medical Association, 2015, v. 313, n. 17, p. 1736, doi. 10.1001/jama.2015.3868
By:
- Muir, Andrew J.;
- Poordad, Fred;
- Lalezari, Jacob;
- Everson, Gregory;
- Dore, Gregory J.;
- Herring, Robert;
- Sheikh, Aasim;
- Kwo, Paul;
- Hézode, Christophe;
- Pockros, Paul J.;
- Tran, Albert;
- Yozviak, Joseph;
- Reau, Nancy;
- Ramji, Alnoor;
- Stuart, Katherine;
- Thompson, Alexander J.;
- Vierling, John;
- Freilich, Bradley;
- Cooper, James;
- Ghesquiere, Wayne
Publication type:
Article
Sofosbuvir and Ribavirin for Hepatitis C in Patients With HIV Coinfection.
Published in:
JAMA: Journal of the American Medical Association, 2014, v. 312, n. 4, p. 353, doi. 10.1001/jama.2014.7734
By:
- Sulkowski, Mark S.;
- Naggie, Susanna;
- Lalezari, Jacob;
- Fessel, Walford Jeffrey;
- Mounzer, Karam;
- Shuhart, Margaret;
- Luetkemeyer, Anne F.;
- Asmuth, David;
- Gaggar, Anuj;
- Liyun Ni;
- Svarovskaia, Evguenia;
- Brainard, Diana M.;
- Symonds, William T.;
- Subramanian, G. Mani;
- McHutchison, John G.;
- Rodriguez-Torres, Maribel;
- Dieterich, Douglas
Publication type:
Article
TURQUOISE-I Part 1b: Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir with Ribavirin for Hepatitis C Virus Infection in HIV-1 Coinfected Patients on Darunavir.
Published in:
2017
By:
- Wyles, David;
- Saag, Michael;
- Viani, Rolando M.;
- Lalezari, Jacob;
- Adeyemi, Oluwatoyin;
- Bhatti, Laveeza;
- Khatri, Amit;
- King, Jennifer R.;
- Hu, Yiran B.;
- Trinh, Roger;
- Shulman, Nancy S.;
- Ruane, Peter
Publication type:
journal article
Safety and Immunogenicity of a Replication-Incompetent Adenovirus Type 5 HIV-1 Clade B gag/pol/nef Vaccine in Healthy Adults.
Published in:
Clinical Infectious Diseases, 2008, v. 46, n. 11, p. 1769, doi. 10.1086/587993
By:
- Priddy, Frances H.;
- Brown, Deborah;
- Kublin, James;
- Monahan, Kathleen;
- Wright, David P.;
- Lalezari, Jacob;
- Santiago, Steven;
- Marmor, Michael;
- Lally, Michelle;
- Novak, Richard M.;
- Brown, Stephen J.;
- Kulkarni, Priya;
- Dubey, Sheri A.;
- Kierstead, Lisa S.;
- Casimiro, Danilo R.;
- Mogg, Robin;
- DiNubile, Mark J.;
- Shiver, John W.;
- Leavitt, Randi Y.;
- Robertson, Michael N.
Publication type:
Article

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