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Identifying homologous recombination deficiency in breast cancer: genomic instability score distributions differ among breast cancer subtypes.
Published in:
Breast Cancer Research & Treatment, 2023, v. 202, n. 1, p. 191, doi. 10.1007/s10549-023-07046-3
By:
- Lenz, Lauren;
- Neff, Chris;
- Solimeno, Cara;
- Cogan, Elizabeth S.;
- Abramson, Vandana G.;
- Boughey, Judy C.;
- Falkson, Carla;
- Goetz, Matthew P.;
- Ford, James M.;
- Gradishar, William J.;
- Jankowitz, Rachel C.;
- Kaklamani, Virginia G.;
- Marcom, P. Kelly;
- Richardson, Andrea L.;
- Storniolo, Anna Maria;
- Tung, Nadine M.;
- Vinayak, Shaveta;
- Hodgson, Darren R.;
- Lai, Zhongwu;
- Dearden, Simon
Publication type:
Article
VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research.
Published in:
Nucleic Acids Research, 2016, v. 44, n. 11, p. 1, doi. 10.1093/nar/gkw227
By:
- Zhongwu Lai;
- Markovets, Aleksandra;
- Ahdesmaki, Miika;
- Chapman, Brad;
- Hofmann, Oliver;
- McEwen, Robert;
- Johnson, Justin;
- Dougherty, Brian;
- Barrett, J. Carl;
- Dry, Jonathan R.
Publication type:
Article
BubbleTree: an intuitive visualization to elucidate tumoral aneuploidy and clonality using next generation sequencing data.
Published in:
Nucleic Acids Research, 2016, v. 44, n. 4, p. 1, doi. 10.1093/nar/gkv1102
By:
- Wei Zhu;
- Kuziora, Michael;
- Creasy, Todd;
- Zhongwu Lai;
- Morehouse, Christopher;
- Xiang Guo;
- Sebastian, Yinong;
- Dong Shen;
- Jiaqi Huang;
- Dry, Jonathan R.;
- Feng Xue;
- Liyan Jiang;
- Yihong Yao;
- Higgs, Brandon W.
Publication type:
Article
Acquired EGFR C797S mutation mediates resistance to AZD9291 in non-small cell lung cancer harboring EGFR T790M.
Published in:
Nature Medicine, 2015, v. 21, n. 6, p. 560, doi. 10.1038/nm.3854
By:
- Thress, Kenneth S;
- Paweletz, Cloud P;
- Felip, Enriqueta;
- Cho, Byoung Chul;
- Stetson, Daniel;
- Dougherty, Brian;
- Lai, Zhongwu;
- Markovets, Aleksandra;
- Vivancos, Ana;
- Kuang, Yanan;
- Ercan, Dalia;
- Matthews, Sarah E;
- Cantarini, Mireille;
- Barrett, J Carl;
- Jänne, Pasi A;
- Oxnard, Geoffrey R
Publication type:
Article
A shotgun optical map of the entire Plasmodium falciparum genome.
Published in:
Nature Genetics, 1999, v. 23, n. 3, p. 309, doi. 10.1038/15484
By:
- Lai, Zhongwu;
- Jing, Junping;
- Aston, Christopher;
- Clarke, Virginia;
- Apodaca, Jennifer;
- Dimalanta, Eileen T.;
- Carucci, Daniel J.;
- Gardner, Malcolm J.;
- Mishra, Bud;
- Anantharaman, Thomas S.;
- Paxia, Salvatore;
- Hoffman, Stephen L.;
- Venter, J. Craig;
- Huff, Edward J.;
- Schwartz, David C.
Publication type:
Article
Uncovering variable neoplasms between ATM protein‐truncating and common missense variants using 394 694 UK Biobank exomes.
Published in:
Genes, Chromosomes & Cancer, 2022, v. 61, n. 9, p. 523, doi. 10.1002/gcc.23042
By:
- Jiang, Xiao;
- O'Neill, Amanda;
- Smith, Katherine R.;
- Lai, Zhongwu;
- Carss, Keren;
- Wang, Quanli;
- Petrovski, Slavé
Publication type:
Article
Homologous Recombination Repair Gene Mutation Characterization by Liquid Biopsy: A Phase II Trial of Olaparib and Abiraterone in Metastatic Castrate-Resistant Prostate Cancer.
Published in:
Cancers, 2021, v. 13, n. 22, p. 5830, doi. 10.3390/cancers13225830
By:
- Carr, T. Hedley;
- Adelman, Carrie;
- Barnicle, Alan;
- Kozarewa, Iwanka;
- Luke, Sally;
- Lai, Zhongwu;
- Hollis, Sally;
- Dougherty, Brian;
- Harrington, Elizabeth A.;
- Kang, Jinyu;
- Saad, Fred;
- Sala, Nuria;
- Thiery-Vuillemin, Antoine;
- Clarke, Noel W.;
- Hodgson, Darren;
- Barrett, J. Carl
Publication type:
Article
Landscape of homologous recombination deficiencies in solid tumours: analyses of two independent genomic datasets.
Published in:
2022
By:
- Lai, Zhongwu;
- Brosnan, Matthew;
- Sokol, Ethan S.;
- Xie, Mingchao;
- Dry, Jonathan R.;
- Harrington, Elizabeth A.;
- Barrett, J. Carl;
- Hodgson, Darren
Publication type:
journal article
Candidate biomarkers of PARP inhibitor sensitivity in ovarian cancer beyond the BRCA genes.
Published in:
2018
By:
- Hodgson, Darren R.;
- Dougherty, Brian A.;
- Lai, Zhongwu;
- Fielding, Anitra;
- Grinsted, Lynda;
- Spencer, Stuart;
- O'Connor, Mark J.;
- Ho, Tony W.;
- Robertson, Jane D.;
- Lanchbury, Jerry S.;
- Timms, Kirsten M.;
- Gutin, Alexander;
- Orr, Maria;
- Jones, Helen;
- Gilks, Blake;
- Womack, Chris;
- Gourley, Charlie;
- Ledermann, Jonathan;
- Barrett, J. Carl
Publication type:
journal article
Molecular classification and biomarkers of outcome with immunotherapy in extensive-stage small-cell lung cancer: analyses of the CASPIAN phase 3 study.
Published in:
Molecular Cancer, 2024, v. 23, p. 1, doi. 10.1186/s12943-024-02014-x
By:
- Xie, Mingchao;
- Vuko, Miljenka;
- Rodriguez-Canales, Jaime;
- Zimmermann, Johannes;
- Schick, Markus;
- O'Brien, Cathy;
- Paz-Ares, Luis;
- Goldman, Jonathan W.;
- Garassino, Marina Chiara;
- Gay, Carl M.;
- Heymach, John V.;
- Jiang, Haiyi;
- Barrett, J. Carl;
- Stewart, Ross A.;
- Lai, Zhongwu;
- Byers, Lauren A.;
- Rudin, Charles M.;
- Shrestha, Yashaswi
Publication type:
Article
Design of a compartmentalized shotgun assembler for the human genome.
Published in:
Bioinformatics, 2001, v. 17, p. 132, doi. 10.1093/bioinformatics/17.suppl_1.s132
By:
- Huson, Daniel H.;
- Reinert, Knut;
- Kravitz, Saul A.;
- Remington, Karin A.;
- Delcher, Art L.;
- Dew, Ian M.;
- Flanigan, Mike;
- Halpern, Aaron L.;
- Lai, Zhongwu;
- Mobarry, Clark M.;
- Sutton, Granger G.;
- Myers, Eugene W.
Publication type:
Article

Found: 11