Found: 9

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  • Development of a Highly Selective Plasmodium falciparum Proteasome Inhibitor with Anti‐malaria Activity in Humanized Mice.

    Published in:
    Angewandte Chemie, 2021, v. 133, n. 17, p. 9365, doi. 10.1002/ange.202015845
    By:
    • Zhan, Wenhu;
    • Zhang, Hao;
    • Ginn, John;
    • Leung, Annie;
    • Liu, Yi J.;
    • Michino, Mayako;
    • Toita, Akinori;
    • Okamoto, Rei;
    • Wong, Tzu‐Tshin;
    • Imaeda, Toshihiro;
    • Hara, Ryoma;
    • Yukawa, Takafumi;
    • Chelebieva, Sevil;
    • Tumwebaze, Patrick K.;
    • Lafuente‐Monasterio, Maria Jose;
    • Martinez‐Martinez, Maria Santos;
    • Vendome, Jeremie;
    • Beuming, Thijs;
    • Sato, Kenjiro;
    • Aso, Kazuyoshi
    Publication type:
    Article

  • Diverse evolutionary pathways challenge the use of collateral sensitivity as a strategy to suppress resistance.

    Published in:
    eLife, 2023, p. 1, doi. 10.7554/eLife.85023
    By:
    • Mandt, Rebecca E. K.;
    • Luth, Madeline R.;
    • Tye, Mark A.;
    • Mazitschek, Ralph;
    • Ottilie, Sabine;
    • Winzeler, Elizabeth A.;
    • Lafuente-Monasterio, Maria Jose;
    • Javier Gamo, Francisco;
    • Wirth, Dyann F.;
    • Lukens, Amanda K.
    Publication type:
    Article

  • A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue.

    Published in:
    Nature Communications, 2017, v. 8, n. 2, p. 14574, doi. 10.1038/ncomms14574
    By:
    • Sonoiki, Ebere;
    • Ng, Caroline L.;
    • Lee, Marcus C. S.;
    • Guo, Denghui;
    • Zhang, Yong-Kang;
    • Zhou, Yasheen;
    • Alley, M. R. K.;
    • Ahyong, Vida;
    • Sanz, Laura M.;
    • Lafuente-Monasterio, Maria Jose;
    • Dong, Chen;
    • Schupp, Patrick G.;
    • Gut, Jiri;
    • Legac, Jenny;
    • Cooper, Roland A.;
    • Gamo, Francisco-Javier;
    • DeRisi, Joseph;
    • Freund, Yvonne R.;
    • Fidock, David A.;
    • Rosenthal, Philip J.
    Publication type:
    Article

  • A broad analysis of resistance development in the malaria parasite.

    Published in:
    Nature Communications, 2016, v. 7, n. 6, p. 11901, doi. 10.1038/ncomms11901
    By:
    • Corey, Victoria C.;
    • Lukens, Amanda K.;
    • Istvan, Eva S.;
    • Lee, Marcus C. S.;
    • Franco, Virginia;
    • Magistrado, Pamela;
    • Coburn-Flynn, Olivia;
    • Sakata-Kato, Tomoyo;
    • Fuchs, Olivia;
    • Gnädig, Nina F.;
    • Goldgof, Greg;
    • Linares, Maria;
    • Gomez-Lorenzo, Maria G.;
    • De Cózar, Cristina;
    • Lafuente-Monasterio, Maria Jose;
    • Prats, Sara;
    • Meister, Stephan;
    • Tanaseichuk, Olga;
    • Wree, Melanie;
    • Zhou, Yingyao
    Publication type:
    Article

  • In vitro selection predicts malaria parasite resistance to dihydroorotate dehydrogenase inhibitors in a mouse infection model.

    Published in:
    Science Translational Medicine, 2019, v. 11, n. 521, p. 1, doi. 10.1126/scitranslmed.aav1636
    By:
    • Mandt, Rebecca E. K.;
    • Lafuente-Monasterio, Maria Jose;
    • Sakata-Kato, Tomoyo;
    • Luth, Madeline R.;
    • Segura, Delfina;
    • Pablos-Tanarro, Alba;
    • Viera, Sara;
    • Magan, Noemi;
    • Ottilie, Sabine;
    • Winzeler, Elizabeth A.;
    • Lukens, Amanda K.;
    • Gamo, Francisco Javier;
    • Wirth, Dyann F.
    Publication type:
    Article

  • Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 387, p. 1, doi. 10.1126/scitranslmed.aad9735
    By:
    • Paquet, Tanya;
    • Le Manach, Claire;
    • González Cabrera, Diego;
    • Younis, Yassir;
    • Henrich, Philipp P.;
    • Abraham, Tara S.;
    • Lee, Marcus C. S.;
    • Basak, Rajshekhar;
    • Ghidelli-Disse, Sonja;
    • Lafuente-Monasterio, María José;
    • Bantscheff, Marcus;
    • Ruecker, Andrea;
    • Blagborough, Andrew M.;
    • Zakutansky, Sara E.;
    • Zeeman, Anne-Marie;
    • White, Karen L.;
    • Shackleford, David M.;
    • Mannila, Janne;
    • Morizzi, Julia;
    • Scheurer, Christian
    Publication type:
    Article

  • Development of a Highly Selective Plasmodium falciparum Proteasome Inhibitor with Anti‐malaria Activity in Humanized Mice.

    Published in:
    Angewandte Chemie International Edition, 2021, v. 60, n. 17, p. 9279, doi. 10.1002/anie.202015845
    By:
    • Zhan, Wenhu;
    • Zhang, Hao;
    • Ginn, John;
    • Leung, Annie;
    • Liu, Yi J.;
    • Michino, Mayako;
    • Toita, Akinori;
    • Okamoto, Rei;
    • Wong, Tzu‐Tshin;
    • Imaeda, Toshihiro;
    • Hara, Ryoma;
    • Yukawa, Takafumi;
    • Chelebieva, Sevil;
    • Tumwebaze, Patrick K.;
    • Lafuente‐Monasterio, Maria Jose;
    • Martinez‐Martinez, Maria Santos;
    • Vendome, Jeremie;
    • Beuming, Thijs;
    • Sato, Kenjiro;
    • Aso, Kazuyoshi
    Publication type:
    Article

  • Biochemical Screening of Five Protein Kinases from Plasmodium falciparum against 14,000 Cell-Active Compounds.

    Published in:
    PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0149996
    By:
    • Crowther, Gregory J.;
    • Hillesland, Heidi K.;
    • Keyloun, Katelyn R.;
    • Reid, Molly C.;
    • Lafuente-Monasterio, Maria Jose;
    • Ghidelli-Disse, Sonja;
    • Leonard, Stephen E.;
    • He, Panqing;
    • Jones, Jackson C.;
    • Krahn, Mallory M.;
    • Mo, Jack S.;
    • Dasari, Kartheek S.;
    • Fox, Anna M. W.;
    • Boesche, Markus;
    • El Bakkouri, Majida;
    • Rivas, Kasey L.;
    • Leroy, Didier;
    • Hui, Raymond;
    • Drewes, Gerard;
    • Maly, Dustin J.
    Publication type:
    Article

  • Development of an ectopic huLiver model for Plasmodium liver stage infection.

    Published in:
    PLoS ONE, 2023, v. 17, n. 3, p. 1, doi. 10.1371/journal.pone.0279144
    By:
    • Samayoa-Reyes, Gabriela;
    • Flaherty, Siobhan M.;
    • Wickham, Kristina S.;
    • Viera-Morilla, Sara;
    • Strauch, Pamela M.;
    • Roth, Alison;
    • Padrón, Laura;
    • Jackson, Conner M.;
    • Meireles, Patricia;
    • Calvo, David;
    • Roobsoong, Wanlapa;
    • Kangwanrangsan, Niwat;
    • Sattabongkot, Jetsumon;
    • Reichard, Gregory;
    • Lafuente-Monasterio, Maria José;
    • Rochford, Rosemary
    Publication type:
    Article