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The epigenetic regulator Smchd1 contains a functional GHKL-type ATPase domain.
- Published in:
- Biochemical Journal, 2016, v. 473, n. 12, p. 1733, doi. 10.1042/BCJ20160189
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- Article
The molecular regulation of Janus kinase (JAK) activation.
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- Biochemical Journal, 2014, v. 462, n. 1, p. 1, doi. 10.1042/BJ20140712
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- Article
Mechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analyses.
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- Biochemical Journal, 2014, v. 458, n. 2, p. 395, doi. 10.1042/BJ20131516
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- Article
Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKL.
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- Biochemical Journal, 2014, v. 457, n. 3, p. 369, doi. 10.1042/BJ20131270
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- Article
Structural basis for small molecule targeting of Doublecortin Like Kinase 1 with DCLK1-IN-1.
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- Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02631-y
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- Article
Ubiquitylation of MLKL at lysine 219 positively regulates necroptosis-induced tissue injury and pathogen clearance.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23474-5
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- Article
SOCS3 binds specific receptor-JAK complexes to control cytokine signaling by direct kinase inhibition.
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- Nature Structural & Molecular Biology, 2013, v. 20, n. 4, p. 469, doi. 10.1038/nsmb.2519
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- Article
Two distinct regions of the large serine recombinase TnpX are required for DNA binding and biological function.
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- Molecular Microbiology, 2006, v. 60, n. 3, p. 591, doi. 10.1111/j.1365-2958.2006.05120.x
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- Article
DNA binding properties of TnpX indicate that different synapses are formed in the excision and integration of the Tn 4451 family.
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- Molecular Microbiology, 2004, v. 53, n. 4, p. 1195, doi. 10.1111/j.1365-2958.2004.04198.x
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- Article
Structural mapping of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3 signaling.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38869-9
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- Article
A regulatory region on RIPK2 is required for XIAP binding and NOD signaling activity.
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- EMBO Reports, 2020, v. 21, n. 11, p. 1, doi. 10.15252/embr.202050400
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- Article
The PEAK family of pseudokinases, their role in cell signalling and cancer.
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- FEBS Journal, 2020, v. 287, n. 19, p. 4183, doi. 10.1111/febs.15087
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- Article
Mapping and functional analysis of heterochromatin protein 1 phosphorylation in the malaria parasite Plasmodium falciparum.
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- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-53325-9
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- Article
Crystal structure of the putative cell‐wall lipoglycan biosynthesis protein LmcA from Mycobacterium smegmatis.
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- Acta Crystallographica: Section D, Structural Biology, 2022, v. 78, n. 4, p. 494, doi. 10.1107/S2059798322001772
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- Article
DCLK1 induces a pro-tumorigenic phenotype to drive gastric cancer progression.
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- Science Signaling, 2024, v. 17, n. 854, p. 1, doi. 10.1126/scisignal.abq4888
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- Article
Distinct PEAK3 interactors and outputs expand the signaling potential of the PEAK pseudokinase family.
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- Science Signaling, 2022, v. 15, n. 722, p. 1, doi. 10.1126/scisignal.abj3554
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- Article
Techniques to examine nucleotide binding by pseudokinases.
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- Biochemical Society Transactions, 2013, v. 41, n. 4, p. 975, doi. 10.1042/BST20130075
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- Article
Regulation of Janus kinases by SOCS proteins.
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- Biochemical Society Transactions, 2013, v. 41, n. 4, p. 1042, doi. 10.1042/BST20130077
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- Article
Structure-Guided Prediction of the Functional Impact of DCLK1 Mutations on Tumorigenesis.
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- Biomedicines, 2023, v. 11, n. 3, p. 990, doi. 10.3390/biomedicines11030990
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- Article
Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis.
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- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04714-7
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- Article
The molecular basis of JAK/STAT inhibition by SOCS1.
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- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04013-1
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- Article
Structure of SgK223 pseudokinase reveals novel mechanisms of homotypic and heterotypic association.
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- Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01279-9
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- Article
Molecular dissection of the pseudokinase ZED1 expands effector recognition to the tomato immune receptor ZAR1.
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- Plant Physiology, 2024, v. 196, n. 1, p. 651, doi. 10.1093/plphys/kiae268
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- Article
Co-clustering of EphB6 and ephrinB1 in trans restrains cancer cell invasion.
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- Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06118-4
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- Article
Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory αC helix.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21191-7
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- Article
Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16823-3
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- Article