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Gene Therapy and Endothelial Cell Targeting for Cancer.
- Published in:
- Annals of the New York Academy of Sciences, 1994, v. 716, n. 1, p. 257, doi. 10.1111/j.1749-6632.1994.tb21717.x
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- Publication type:
- Article
Cationic Liposomes for Direct Gene Transfer in Therapy of Cancer and Other Diseasesa.
- Published in:
- Annals of the New York Academy of Sciences, 1994, v. 716, n. 1, p. 23, doi. 10.1111/j.1749-6632.1994.tb21701.x
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- Publication type:
- Article
The hubris and humility of cancer pharmacology in the post immuno-oncology era.
- Published in:
- Pharmacology Research & Perspectives, 2019, v. 7, n. 6, p. 1, doi. 10.1002/prp2.527
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- Publication type:
- Article
Small molecule inhibitors of dual specificity protein phosphatases.
- Published in:
- Oncogene, 2000, v. 19, n. 56, p. 6607, doi. 10.1038/sj.onc.1204084
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- Publication type:
- Article
Dual G1 and G2/M phase inhibition by SC-ααδ9, a combinatorially derived Cdc25 phosphatase inhibitor.
- Published in:
- Oncogene, 1999, v. 18, n. 50, p. 6989, doi. 10.1038/sj.onc.1203179
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- Publication type:
- Article
Cell cycle dependent subcellular distribution of Cdc25B subtypes.
- Published in:
- Oncogene, 1999, v. 18, n. 17, p. 2770, doi. 10.1038/sj.onc.1202614
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- Publication type:
- Article
Deactivation of STAT3 and ERK and Activation of p38 in Ovarian Cancer Cells Treated with a Small Molecule Inhibitor of PTP4A3 Phosphatase.
- Published in:
- FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R2345
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- Publication type:
- Article
A chemical genetics approach identifies PTP4A3 as a regulator of colon cancer cell adhesion.
- Published in:
- FASEB Journal, 2018, v. 32, n. 10, p. 5661, doi. 10.1096/fj.201701446R
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- Publication type:
- Article
Pharmacological profiling identifies divergent chemosensitivities of differentiating and maturing iPSC‐derived human cortical neuron populations.
- Published in:
- FEBS Journal, 2023, v. 290, n. 20, p. 4950, doi. 10.1111/febs.16901
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- Publication type:
- Article
Optimization of ultrasound contrast agents with computational models to improve selection of ligands and binding strength.
- Published in:
- Biotechnology & Bioengineering, 2010, v. 107, n. 5, p. 854, doi. 10.1002/bit.22857
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- Publication type:
- Article
Metallothionein modulates the carcinogenicity of N-butyl-N-(4-hydroxybutyl)nitrosamine in mice.
- Published in:
- Carcinogenesis, 1999, v. 20, n. 8, p. 1625, doi. 10.1093/carcin/20.8.1625
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- Publication type:
- Article
Effect of Pharmacological Inhibition of the Catalytic Activity of Phosphatases of Regenerating Liver in Early T Cell Receptor Signaling Dynamics and IL-2 Production.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 7, p. 2530, doi. 10.3390/ijms21072530
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- Publication type:
- Article
Novel protein kinase D inhibitors cause potent arrest in prostate cancer cell growth and motility.
- Published in:
- BMC Chemical Biology, 2010, v. 10, p. 5, doi. 10.1186/1472-6769-10-5
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- Publication type:
- Article
Mitotic slippage in non-cancer cells induced by a microtubule disruptor, disorazole C<sub>1</sub>.
- Published in:
- BMC Chemical Biology, 2010, v. 10, p. 1, doi. 10.1186/1472-6769-10-1
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- Publication type:
- Article
Diallyl trisulfide-induced G<sub>2</sub>–M phase cell cycle arrest in human prostate cancer cells is caused by reactive oxygen species-dependent destruction and hyperphosphorylation of Cdc25C.
- Published in:
- Oncogene, 2005, v. 24, n. 41, p. 6256, doi. 10.1038/sj.onc.1208759
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- Publication type:
- Article
Low molecular weight inhibitors of Myc-Max interaction and function.
- Published in:
- Oncogene, 2003, v. 22, n. 40, p. 6151, doi. 10.1038/sj.onc.1206641
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- Publication type:
- Article
A Target-Based High Throughput Screen Yields Trypanosoma brucei Hexokinase Small Molecule Inhibitors with Antiparasitic Activity.
- Published in:
- PLoS Neglected Tropical Diseases, 2010, v. 4, n. 4, p. 1, doi. 10.1371/journal.pntd.0000659
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- Publication type:
- Article
A Target-Based High Throughput Screen Yields Trypanosoma brucei Hexokinase Small Molecule Inhibitors with Antiparasitic Activity.
- Published in:
- PLoS Neglected Tropical Diseases, 2010, v. 4, n. 4, p. 1, doi. 10.1371/journal.pntd.0000659
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- Publication type:
- Article
Identification of Potent Chemotypes Targeting Leishmania major Using a High-Throughput, Low-Stringency, Computationally Enhanced, Small Molecule Screen.
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- PLoS Neglected Tropical Diseases, 2009, v. 3, n. 11, p. 1, doi. 10.1371/journal.pntd.0000540
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- Publication type:
- Article
Identification of Potent Chemotypes Targeting Leishmania major Using a High-Throughput, Low-Stringency, Computationally Enhanced, Small Molecule Screen.
- Published in:
- PLoS Neglected Tropical Diseases, 2009, v. 3, n. 11, p. 1, doi. 10.1371/journal.pntd.0000540
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- Publication type:
- Article
Antitumor and Toxic Effects of Combination Chemotherapy With Bleomycin and a Phenothiazine Anticalmodulin Agent23.
- Published in:
- JNCI: Journal of the National Cancer Institute, 1988, v. 80, n. 4, p. 246, doi. 10.1093/jnci/80.4.246
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- Publication type:
- Article
Targeted Deletion of the Metastasis-Associated Phosphatase <i>Ptp4a3</i> (PRL-3) Suppresses Murine Colon Cancer.
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- PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0058300
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- Publication type:
- Article
Discovery of Diverse Small Molecule Chemotypes with Cell-Based PKD1 Inhibitory Activity.
- Published in:
- PLoS ONE, 2011, v. 6, n. 10, p. 1, doi. 10.1371/journal.pone.0025134
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- Publication type:
- Article
Automated High-Content Live Animal Drug Screening Using C. elegans Expressing the Aggregation Prone Serpin α1-antitrypsin Z.
- Published in:
- PLoS ONE, 2010, v. 5, n. 11, p. 1, doi. 10.1371/journal.pone.0015460
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- Publication type:
- Article
Synthesis and Biological Activity of a Focused Library of Mitogen-activated Protein Kinase Phosphatase Inhibitors.
- Published in:
- Chemical Biology & Drug Design, 2007, v. 69, n. 1, p. 23, doi. 10.1111/j.1747-0285.2007.00474.x
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- Publication type:
- Article
Cellular Analysis of Disorazole C<sub>1</sub> and Structure–Activity Relationship of Analogs of the Natural Product.
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- Chemical Biology & Drug Design, 2006, v. 67, n. 1, p. 66, doi. 10.1111/j.1747-0285.2005.00313.x
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- Publication type:
- Article
Discovery of Benzisothiazolone Derivatives as Bifunctional Inhibitors of HIV-1 Reverse Transcriptase DNA Polymerase and Ribonuclease H Activities.
- Published in:
- Biomolecules (2218-273X), 2024, v. 14, n. 7, p. 819, doi. 10.3390/biom14070819
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- Publication type:
- Article
Credentialing and Pharmacologically Targeting PTP4A3 Phosphatase as a Molecular Target for Ovarian Cancer.
- Published in:
- Biomolecules (2218-273X), 2021, v. 11, n. 7, p. 969, doi. 10.3390/biom11070969
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- Publication type:
- Article
Synthesis and biological evaluation of a targeted library of protein phosphatase inhibitors.
- Published in:
- Biotechnology & Bioengineering, 2000, v. 71, n. 1, p. 58, doi. 10.1002/(SICI)1097-0290(200024)71:1<58::AID-BIT9>3.0.CO;2-0
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- Publication type:
- Article
The Promise and Perils of Compound Discovery Screening with Inducible Pluripotent Cell-Derived Neurons.
- Published in:
- Assay & Drug Development Technologies, 2020, v. 18, n. 2, p. 97, doi. 10.1089/adt.2019.914
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- Publication type:
- Article
Development and Implementation of a High-Throughput High-Content Screening Assay to Identify Inhibitors of Androgen Receptor Nuclear Localization in Castration-Resistant Prostate Cancer Cells.
- Published in:
- Assay & Drug Development Technologies, 2016, v. 14, n. 4, p. 226, doi. 10.1089/adt.2016.716
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- Publication type:
- Article
HCS Campaign to Identify Selective Inhibitors of IL-6-Induced STAT3 Pathway Activation in Head and Neck Cancer Cell Lines.
- Published in:
- Assay & Drug Development Technologies, 2015, v. 13, n. 7, p. 356, doi. 10.1089/adt.2015.663
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- Publication type:
- Article
High-Content pSTAT3/1 Imaging Assays to Screen for Selective Inhibitors of STAT3 Pathway Activation in Head and Neck Cancer Cell Lines.
- Published in:
- Assay & Drug Development Technologies, 2014, v. 12, n. 1, p. 55, doi. 10.1089/adt.2013.524
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- Publication type:
- Article
Development and Validation of a High-Content Screening Assay to Identify Inhibitors of Cytoplasmic Dynein-Mediated Transport of Glucocorticoid Receptor to the Nucleus.
- Published in:
- Assay & Drug Development Technologies, 2012, v. 10, n. 5, p. 432, doi. 10.1089/adt.2012.456
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- Publication type:
- Article
Characterization and Optimization of a Novel Protein–Protein Interaction Biosensor High-Content Screening Assay to Identify Disruptors of the Interactions Between p53 and hDM2.
- Published in:
- Assay & Drug Development Technologies, 2010, v. 8, n. 4, p. 437, doi. 10.1089/adt.2010.0281
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- Publication type:
- Article
Profiling the NIH Small Molecule Repository for Compounds That Generate H2O2by Redox Cycling in Reducing Environments.
- Published in:
- Assay & Drug Development Technologies, 2010, v. 8, n. 2, p. 152, doi. 10.1089/adt.2009.0247
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- Publication type:
- Article
Cdc25B Dual-Specificity Phosphatase Inhibitors Identified in a High-Throughput Screen of the NIH Compound Library.
- Published in:
- Assay & Drug Development Technologies, 2009, v. 7, n. 3, p. 250, doi. 10.1089/adt.2008.186
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- Publication type:
- Article
Development of a 384-Well Colorimetric Assay to Quantify Hydrogen Peroxide Generated by the Redox Cycling of Compounds in the Presence of Reducing Agents.
- Published in:
- Assay & Drug Development Technologies, 2008, v. 6, n. 4, p. 505, doi. 10.1089/adt.2008.151
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- Publication type:
- Article
Development and Implementation of a Miniaturized High-Throughput Time-Resolved Fluorescence Energy Transfer Assay to Identify Small Molecule Inhibitors of Polo-Like Kinase 1.
- Published in:
- Assay & Drug Development Technologies, 2007, v. 5, n. 6, p. 723, doi. 10.1089/adt.2007.102
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- Publication type:
- Article
HTS Identifies Novel and Specific Uncompetitive Inhibitors of the Two-Component NS2B-NS3 Proteinase of West Nile Virus.
- Published in:
- Assay & Drug Development Technologies, 2007, v. 5, n. 6, p. 737, doi. 10.1089/adt.2007.101
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- Publication type:
- Article
Development and Implementation of a 384-Well Homogeneous Fluorescence Intensity High-Throughput Screening Assay to Identify Mitogen-Activated Protein Kinase Phosphatase-1 Dual-Specificity Protein Phosphatase Inhibitors.
- Published in:
- Assay & Drug Development Technologies, 2007, v. 5, n. 3, p. 319, doi. 10.1089/adt.2007.066
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- Publication type:
- Article
Systems Cell Biology Knowledge Created fromHigh Content Screening.
- Published in:
- Assay & Drug Development Technologies, 2005, v. 3, n. 5, p. 501
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- Publication type:
- Article
Energy-dependent nuclear binding dictates metallothionein localization.
- Published in:
- Journal of Cellular Physiology, 2000, v. 182, n. 1, p. 69, doi. 10.1002/(SICI)1097-4652(200001)182:1<69::AID-JCP8>3.0.CO;2-9
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- Publication type:
- Article
Protein phosphorylation in cultured endothelial cells.
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- Journal of Cellular Physiology, 1986, v. 128, n. 3, p. 367, doi. 10.1002/jcp.1041280304
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- Article
Review: Drug Discovery Algorithm for Cutaneous Leishmaniasis.
- Published in:
- American Journal of Tropical Medicine & Hygiene, 2013, v. 88, n. 2, p. 216, doi. 10.4269/ajtmh.11-0812
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- Publication type:
- Article
Automated image-based phenotypic analysis in zebrafish embryos.
- Published in:
- Developmental Dynamics, 2009, v. 238, n. 3, p. 656, doi. 10.1002/dvdy.21892
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- Publication type:
- Article
Efficacy, pharmacokinetics, tisssue distribution, and metabolism of the Myc-Max disruptor, 10058-F4 [Z,E]-5-[4-ethylbenzylidine]-2-thioxothiazolidin-4-one, in mice.
- Published in:
- 2009
- By:
- Publication type:
- journal article
Dual-specificity phosphatases as targets for antineoplastic agents.
- Published in:
- Nature Reviews Drug Discovery, 2002, v. 1, n. 12, p. 961, doi. 10.1038/nrd963
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- Publication type:
- Article
Activation of the Raf-1/MEK/Erk kinase pathway by a novel Cdc25 inhibitor in human prostate cancer cells.
- Published in:
- Prostate, 2004, v. 58, n. 1, p. 95, doi. 10.1002/pros.10292
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- Publication type:
- Article
Design, Synthesis, and Biological Evaluation of PKD Inhibitors.
- Published in:
- Pharmaceutics, 2011, v. 3, n. 2, p. 186, doi. 10.3390/pharmaceutics3020186
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- Publication type:
- Article