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Genetic proof for the transient nature of the Th17 phenotype.
Published in:
European Journal of Immunology, 2010, v. 40, n. 12, p. 3336, doi. 10.1002/eji.201040755
By:
- Kurschus, Florian C.;
- Croxford, Andrew L.;
- P. Heinen, André;
- Wörtge, Simone;
- Ielo, Daniele;
- Waisman, Ari
Publication type:
Article
Review—Current Concepts in Inflammatory Skin Diseases Evolved by Transcriptome Analysis: In-Depth Analysis of Atopic Dermatitis and Psoriasis.
Published in:
International Journal of Molecular Sciences, 2020, v. 21, n. 3, p. 699, doi. 10.3390/ijms21030699
By:
- Schwingen, Julius;
- Kaplan, Mustafa;
- Kurschus, Florian C.
Publication type:
Article
Receptor for advanced glycation end products (RAGE)regulates sepsis but not the adaptive immune response.
Published in:
Journal of Clinical Investigation, 2004, v. 113, n. 11, p. 1641, doi. 10.1172/JCI200418704
By:
- Liliensiek, Birgit;
- Weigand, Markus A.;
- Bierhaus, Angelika;
- Nicklas, Werner;
- Kasper, Michael;
- Hofer, Stefan;
- Plachky, Jens;
- Gröne, Herman-Josef;
- Kurschus, Florian C.;
- Schmidt, Ann Marie;
- Shi Du Yan;
- Martin, Eike;
- Schleicher, Erwin;
- Stern, David M.;
- Hämmerling, Günter J.;
- Nawroth, Peter P.;
- Arnold, Bernd
Publication type:
Article
Experimental autoimmune encephalomyelitis in mice expressing the autoantigen MBP110 covalently bound to the MHC class II molecule I-Au.
Published in:
International Immunology, 2006, v. 18, n. 1, p. 151, doi. 10.1093/intimm/dxh357
By:
- Florian C. Kurschus;
- Thilo Oelert;
- Birgit Liliensiek;
- Pascale Buchmann;
- David C. Wraith;
- Gnter J. Hmmerling;
- Bernd Arnold
Publication type:
Article
Myelin-specific T cells also recognize neuronal autoantigen in a transgenic mouse model of multiple sclerosis.
Published in:
Nature Medicine, 2009, v. 15, n. 6, p. 626, doi. 10.1038/nm.1975
By:
- Krishnamoorthy, Gurumoorthy;
- Saxena, Amit;
- Mars, Lennart T.;
- Domingues, Helena S.;
- Mentele, Reinhard;
- Ben-Nun, Avraham;
- Lassmann, Hans;
- Dornmair, Klaus;
- Kurschus, Florian C.;
- Liblau, Roland S.;
- Wekerle, Hartmut
Publication type:
Article
The actin remodeling protein cofilin is crucial for thymic αβ but not γδ T-cell development.
Published in:
PLoS Biology, 2018, v. 16, n. 7, p. 1, doi. 10.1371/journal.pbio.2005380
By:
- Seeland, Isabel;
- Xiong, Ying;
- Orlik, Christian;
- Deibel, Daniel;
- Prokosch, Sandra;
- Küblbeck, Günter;
- Jahraus, Beate;
- De Stefano, Daniela;
- Moos, Sonja;
- Kurschus, Florian C.;
- Arnold, Bernd;
- Samstag, Yvonne
Publication type:
Article
IL-17+ CD8+ T cell suppression by dimethyl fumarate associates with clinical response in multiple sclerosis.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-13731-z
By:
- Lückel, Christina;
- Picard, Felix;
- Raifer, Hartmann;
- Campos Carrascosa, Lucia;
- Guralnik, Anna;
- Zhang, Yajuan;
- Klein, Matthias;
- Bittner, Stefan;
- Steffen, Falk;
- Moos, Sonja;
- Marini, Federico;
- Gloury, Renee;
- Kurschus, Florian C.;
- Chao, Ying-Yin;
- Bertrams, Wilhelm;
- Sexl, Veronika;
- Schmeck, Bernd;
- Bonetti, Lynn;
- Grusdat, Melanie;
- Lohoff, Michael
Publication type:
Article
Lugdunin amplifies innate immune responses in the skin in synergy with host- and microbiota-derived factors.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10646-7
By:
- Bitschar, Katharina;
- Sauer, Birgit;
- Focken, Jule;
- Dehmer, Hanna;
- Moos, Sonja;
- Konnerth, Martin;
- Schilling, Nadine A.;
- Grond, Stephanie;
- Kalbacher, Hubert;
- Kurschus, Florian C.;
- Götz, Friedrich;
- Krismer, Bernhard;
- Peschel, Andreas;
- Schittek, Birgit
Publication type:
Article
Improved method to retain cytosolic reporter protein fluorescence while staining for nuclear proteins.
Published in:
Cytometry. Part A, 2014, v. 85, n. 7, p. 621, doi. 10.1002/cyto.a.22451
By:
- Heinen, André P.;
- Wanke, Florian;
- Moos, Sonja;
- Attig, Sebastian;
- Luche, Hervé;
- Pal, Prajna Paramita;
- Budisa, Nediljko;
- Fehling, Hans Jörg;
- Waisman, Ari;
- Kurschus, Florian C.
Publication type:
Article
IL-1 signaling is critical for expansion but not generation of autoreactive GM- CSF<sup>+</sup> Th17 cells.
Published in:
EMBO Journal, 2017, v. 36, n. 1, p. 102, doi. 10.15252/embj.201694615
By:
- Mufazalov, Ilgiz A;
- Schelmbauer, Carsten;
- Regen, Tommy;
- Kuschmann, Janina;
- Wanke, Florian;
- Gabriel, Laureen A;
- Hauptmann, Judith;
- Müller, Werner;
- Pinteaux, Emmanuel;
- Kurschus, Florian C;
- Waisman, Ari
Publication type:
Article
Delivery and therapeutic potential of human granzyme B.
Published in:
Immunological Reviews, 2010, v. 235, n. 1, p. 159, doi. 10.1111/j.0105-2896.2010.00894.x
By:
- Kurschus, Florian C.;
- Jenne, Dieter E.
Publication type:
Article
IL-6 Regulates Neutrophil Microabscess Formation in IL-17A-Driven Psoriasiform Lesions.
Published in:
Journal of Investigative Dermatology, 2014, v. 134, n. 3, p. 728, doi. 10.1038/jid.2013.404
By:
- Croxford, Andrew L;
- Karbach, Susanne;
- Kurschus, Florian C;
- Wörtge, Simone;
- Nikolaev, Alexei;
- Yogev, Nir;
- Klebow, Sabrina;
- Schüler, Rebecca;
- Reissig, Sonja;
- Piotrowski, Carolin;
- Brylla, Elke;
- Bechmann, Ingo;
- Scheller, Jürgen;
- Rose-John, Stefan;
- Wunderlich, F Thomas;
- Münzel, Thomas;
- von Stebut, Esther;
- Waisman, Ari
Publication type:
Article
An Alternative Pathway of Imiquimod-Induced Psoriasis-Like Skin Inflammation in the Absence of Interleukin-17 Receptor A Signaling.
Published in:
Journal of Investigative Dermatology, 2013, v. 133, n. 2, p. 441, doi. 10.1038/jid.2012.318
By:
- El Malki, Khalifa;
- Karbach, Susanne H;
- Huppert, Jula;
- Zayoud, Morad;
- Reißig, Sonja;
- Schüler, Rebecca;
- Nikolaev, Alexej;
- Karram, Khalad;
- Münzel, Thomas;
- Kuhlmann, Christoph R W;
- Luhmann, Heiko J;
- Von Stebut, Esther;
- Wörtge, Simone;
- Kurschus, Florian C;
- Waisman, Ari
Publication type:
Article
Interleukin-1 promotes autoimmune neuroinflammation by suppressing endothelial heme oxygenase-1 at the blood–brain barrier.
Published in:
Acta Neuropathologica, 2020, v. 140, n. 4, p. 549, doi. 10.1007/s00401-020-02187-x
By:
- Hauptmann, Judith;
- Johann, Lisa;
- Marini, Federico;
- Kitic, Maja;
- Colombo, Elisa;
- Mufazalov, Ilgiz A.;
- Krueger, Martin;
- Karram, Khalad;
- Moos, Sonja;
- Wanke, Florian;
- Kurschus, Florian C.;
- Klein, Matthias;
- Cardoso, Silvia;
- Strauß, Judith;
- Bolisetty, Subhashini;
- Lühder, Fred;
- Schwaninger, Markus;
- Binder, Harald;
- Bechman, Ingo;
- Bopp, Tobias
Publication type:
Article
Crystal structure of the apoptosis-inducing human granzyme A dimer.
Published in:
Nature Structural Biology, 2003, v. 10, n. 7, p. 535, doi. 10.1038/nsb945
By:
- Hink-Schauer, Clara;
- Estebanez-Perpina, Eva;
- Kurschus, Florian C;
- Bode, Wolfram;
- Jenne, Dieter E
Publication type:
Article
Inflammatory demyelination induces glia alterations and ganglion cell loss in the retina of an experimental autoimmune encephalomyelitis model.
Published in:
2013
By:
- Horstmann, Lioba;
- Schmid, Heiko;
- Heinen, André P.;
- Kurschus, Florian C.;
- Dick, H. Burkhard;
- Joachim, Stephanie C.
Publication type:
journal article
TLR-4 ligation of dendritic cells is sufficient to drive pathogenic T cell function in experimental autoimmune encephalomyelitis.
Published in:
Journal of Neuroinflammation, 2012, v. 9, n. 1, p. 248, doi. 10.1186/1742-2094-9-248
By:
- Mellanby, Richard J.;
- Cambrook, Helen;
- Turner, Darryl G.;
- O'Connor, Richard A.;
- Leech, Melanie D.;
- Kurschus, Florian C.;
- MacDonald, Andrew S.;
- Arnold, Bernd;
- Anderton, Stephen M.
Publication type:
Article
Expression of IL-17F is associated with non-pathogenic Th17 cells.
Published in:
Journal of Molecular Medicine, 2018, v. 96, n. 8, p. 819, doi. 10.1007/s00109-018-1662-5
By:
- Wanke, Florian;
- Tang, Yilang;
- Gronke, Konrad;
- Klebow, Sabrina;
- Moos, Sonja;
- Hauptmann, Judith;
- Shanmugavadivu, Arthi;
- Regen, Tommy;
- Mufazalov, Ilgiz A.;
- Gabriel, Lauren A.;
- Reißig, Sonja;
- Diefenbach, Andreas;
- Kurschus, Florian C.;
- Waisman, Ari
Publication type:
Article
Killing of target cells by redirected granzyme B in the absence of perforin
Published in:
FEBS Letters, 2004, v. 562, n. 1-3, p. 87, doi. 10.1016/S0014-5793(04)00187-5
By:
- Kurschus, Florian C.;
- Kleinschmidt, Martin;
- Fellows, Edward;
- Dornmair, Klaus;
- Rudolph, Rainer;
- Lilie, Hauke;
- Jenne, Dieter E.
Publication type:
Article

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