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Mechanistically Coupled PK (MCPK) Model to Describe Enzyme Induction and Occupancy Dependent DDI of Dabrafenib Metabolism.
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- Pharmaceutics, 2022, v. 14, n. 2, p. 310, doi. 10.3390/pharmaceutics14020310
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- Article
The Role of AKT/mTOR Pathway in Stress Response to UV-Irradiation: Implication in Skin Carcinogenesis by Regulation of Apoptosis, Autophagy and Senescence.
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- International Journal of Molecular Sciences, 2013, v. 14, n. 8, p. 15260, doi. 10.3390/ijms140815260
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- Article
Analysing the Role of UVB-Induced Translational Inhibition and PP2Ac Deactivation in NF-κB Signalling Using a Minimal Mathematical Model.
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- PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0040274
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- Article
Computational models of melanoma.
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- Theoretical Biology & Medical Modelling, 2020, v. 17, n. 1, p. 1, doi. 10.1186/s12976-020-00126-7
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- Article
XIAP promotes melanoma growth by inducing tumour neutrophil infiltration.
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- EMBO Reports, 2022, v. 23, n. 6, p. 1, doi. 10.15252/embr.202153608
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- Article
DNA damage, death receptor activation and reactive oxygen species contribute o ultraviolet radiation-induced apoptosis in an essential and independent way.
- Published in:
- Oncogene, 2002, v. 21, n. 38, p. 5844, doi. 10.1038/sj.onc.1205743
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- Article
Interleukin-12 suppresses ultraviolet radiation-induced apoptosis by inducing DNA repair.
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- Nature Cell Biology, 2002, v. 4, n. 1, p. 26, doi. 10.1038/ncb717
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- Article
Identification of New IκBα Complexes by an Iterative Experimental and Mathematical Modeling Approach.
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- PLoS Computational Biology, 2014, v. 10, n. 3, p. 1, doi. 10.1371/journal.pcbi.1003528
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- Article
Systemic network analysis identifies XIAP and IκBα as potential drug targets in TRAIL resistant BRAF mutated melanoma.
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- NPJ Systems Biology & Applications, 2018, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41540-018-0075-y
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- Article
Anti-Apoptotic NF-κB and 'Gain of Function' mutp53 in Concert Act Pro-Apoptotic in Response to UVB+IL-1 via Enhanced TNF Production.
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- Journal of Investigative Dermatology, 2015, v. 135, n. 3, p. 851, doi. 10.1038/jid.2014.481
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- Article
The Farnesyl Transferase Inhibitor Lonafarnib Inhibits mTOR Signaling and Enforces Sorafenib-Induced Apoptosis in Melanoma Cells.
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- Journal of Investigative Dermatology, 2011, v. 131, n. 2, p. 468, doi. 10.1038/jid.2010.297
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- Article
Inhibition of PI3K-AKT-mTOR Signaling Sensitizes Melanoma Cells to Cisplatin and Temozolomide.
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- Journal of Investigative Dermatology, 2009, v. 129, n. 6, p. 1500, doi. 10.1038/jid.2008.379
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- Article
Combined Inhibition of MAPK and mTOR Signaling Inhibits Growth, Induces Cell Death, and Abrogates Invasive Growth of Melanoma Cells.
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- Journal of Investigative Dermatology, 2008, v. 128, n. 8, p. 2013, doi. 10.1038/jid.2008.44
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- Article
Resistance of Human Melanoma Cells Against the Death Ligand TRAIL Is Reversed by Ultraviolet-B Radiation via Downregulation of FLIP.
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- Journal of Investigative Dermatology, 2004, v. 123, n. 4, p. 746, doi. 10.1111/j.0022-202X.2004.23420.x
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- Article
20 Years After--Milestones in Molecular Photobiology.
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- Journal of Investigative Dermatology, 2002, v. 119, p. 46
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- Article
A cytosolic mutp53(E285K) variant confers chemoresistance of malignant melanoma.
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- Cell Death & Disease, 2023, v. 14, n. 12, p. 1, doi. 10.1038/s41419-023-06360-4
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- Article
Metabolic modelling-based in silico drug target prediction identifies six novel repurposable drugs for melanoma.
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- Cell Death & Disease, 2023, v. 14, n. 7, p. 1, doi. 10.1038/s41419-023-05955-1
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- Article
Focal adhesion kinase plays a dual role in TRAIL resistance and metastatic outgrowth of malignant melanoma.
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- Cell Death & Disease, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41419-022-04502-8
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- Article
Cell death and regeneration in Dresden—the 27th meeting of the European Cell Death Organization.
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- Cell Death & Disease, 2019, v. 10, n. 12, p. 1, doi. 10.1038/s41419-019-2153-5
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- Article
RL2 Enhances the Elimination of Breast Cancer Cells by Doxorubicin.
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- Cells (2073-4409), 2023, v. 12, n. 24, p. 2779, doi. 10.3390/cells12242779
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- Article