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Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1.
- Published in:
- eLife, 2016, p. 1, doi. 10.7554/eLife.17101
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- Publication type:
- Article
Comparative biochemical analysis of UHRF proteins reveals molecular mechanisms that uncouple UHRF2 from DNA methylation maintenance.
- Published in:
- Nucleic Acids Research, 2018, v. 46, n. 9, p. 4405, doi. 10.1093/nar/gky151
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- Article
SwiftLib: rapid degenerate-codon-library optimization through dynamic programming.
- Published in:
- Nucleic Acids Research, 2015, v. 43, n. 5, p. 1, doi. 10.1093/nar/gku1323
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- Article
Requirements for 5′dRP/AP lyase activity in Ku.
- Published in:
- Nucleic Acids Research, 2014, v. 42, n. 17, p. 11136, doi. 10.1093/nar/gku796
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- Article
Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface.
- Published in:
- Nature Biotechnology, 2014, v. 32, n. 2, p. 191, doi. 10.1038/nbt.2797
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- Article
Cages from coils.
- Published in:
- Nature Biotechnology, 2013, v. 31, n. 9, p. 809, doi. 10.1038/nbt.2670
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- Article
Hold me tightly LOV.
- Published in:
- Nature Methods, 2010, v. 7, n. 8, p. 595, doi. 10.1038/nmeth0810-595
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- Article
Site-specific monoubiquitination activates Ras by impeding GTPase-activating protein function.
- Published in:
- Nature Structural & Molecular Biology, 2013, v. 20, n. 1, p. 46, doi. 10.1038/nsmb.2430
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- Article
E2 conjugating enzymes must disengage from their E1 enzymes before E3-dependent ubiquitin and ubiquitin-like transfer.
- Published in:
- Nature Structural & Molecular Biology, 2005, v. 12, n. 10, p. 933, doi. 10.1038/nsmb984
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- Article
Control of Protein Activity and Cell Fate Specification via Light-Mediated Nuclear Translocation.
- Published in:
- PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0128443
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- Article
Adding Diverse Noncanonical Backbones to Rosetta: Enabling Peptidomimetic Design.
- Published in:
- PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0067051
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- Article
Alternative Computational Protocols for Supercharging Protein Surfaces for Reversible Unfolding and Retention of Stability
- Published in:
- PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0064363
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- Publication type:
- Article
Serverification of Molecular Modeling Applications: The Rosetta Online Server That Includes Everyone (ROSIE)
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- PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063906
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- Publication type:
- Article
Incorporation of Noncanonical Amino Acids into Rosetta and Use in Computational Protein-Peptide Interface Design.
- Published in:
- PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0032637
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- Publication type:
- Article
A Generic Program for Multistate Protein Design.
- Published in:
- PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0020937
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- Article
Anchored Design of Protein-Protein Interfaces.
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- PLoS ONE, 2011, v. 6, n. 6, p. 1, doi. 10.1371/journal.pone.0020872
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- Publication type:
- Article
Combined computational design of a zinc-binding site and a protein-protein interaction: One open zinc coordination site was not a robust hotspot for de novo ubiquitin binding.
- Published in:
- Proteins, 2013, v. 81, n. 9, p. 1678, doi. 10.1002/prot.24379
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- Publication type:
- Article
Combined computational design of a zinc-binding site and a protein-protein interaction: One open zinc coordination site was not a robust hotspot for de novo ubiquitin binding.
- Published in:
- Proteins, 2013, v. 81, n. 7, p. 1245, doi. 10.1002/prot.24280
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- Article
Computational protein design with explicit consideration of surface hydrophobic patches.
- Published in:
- Proteins, 2012, v. 80, n. 3, p. 825, doi. 10.1002/prot.23241
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- Publication type:
- Article
Computational design of second-site suppressor mutations at protein-protein interfaces.
- Published in:
- Proteins, 2010, v. 78, n. 4, p. 1055, doi. 10.1002/prot.22631
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- Article
Using quantum mechanics to improve estimates of amino acid side chain rotamer energies.
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- Proteins, 2008, v. 71, n. 4, p. 1637, doi. 10.1002/prot.21845
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- Article
Protein design simulations suggest that side-chain conformational entropy is not a strong determinant of amino acid environmental preferences.
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- Proteins, 2006, v. 62, n. 3, p. 739, doi. 10.1002/prot.20786
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- Article
A 'solvated rotamer' approach to modeling water-mediated hydrogen bonds at protein-protein interfaces.
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- Proteins, 2005, v. 58, n. 4, p. 893, doi. 10.1002/prot.20347
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- Article
An improved protein decoy set for testing energy functions for protein structure prediction.
- Published in:
- Proteins, 2003, v. 53, n. 1, p. 76, doi. 10.1002/prot.10454
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- Publication type:
- Article
Light‐Dependent Cytoplasmic Recruitment Enhances the Dynamic Range of a Nuclear Import Photoswitch.
- Published in:
- ChemBioChem, 2018, v. 19, n. 12, p. 1319, doi. 10.1002/cbic.201700681
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- Article
A genetically encoded photoactivatable Rac controls the motility of living cells.
- Published in:
- Nature, 2009, v. 461, n. 7260, p. 104, doi. 10.1038/nature08241
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- Publication type:
- Article
RosettaDesign server for protein design.
- Published in:
- Nucleic Acids Research, 2006, v. 34, n. 11, p. w235, doi. 10.1093/nar/gkl163
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- Publication type:
- Article
Using anchoring motifs for the computational design of protein-protein interactions.
- Published in:
- Biochemical Society Transactions, 2013, v. 41, n. 5, p. 1141, doi. 10.1042/BST20130108
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- Publication type:
- Article
Probing the minimal determinants of zinc binding with computational protein design.
- Published in:
- PEDS: Protein Engineering, Design & Selection, 2016, v. 29, n. 8, p. 327, doi. 10.1093/protein/gzw026
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- Article
Labelling and optical erasure of synaptic memory traces in the motor cortex.
- Published in:
- Nature, 2015, v. 525, n. 7569, p. 333, doi. 10.1038/nature15257
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- Article
Computer‐based engineering of thermostabilized antibody fragments.
- Published in:
- AIChE Journal, 2020, v. 66, n. 3, p. N.PAG, doi. 10.1002/aic.16864
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- Article
The Rodin-Ohno hypothesis that two enzyme superfamilies descended from one ancestral gene: an unlikely scenario for the origins of translation that will not be dismissed.
- Published in:
- Biology Direct, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1745-6150-9-11
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- Article
Maintaining solvent accessible surface area under rotamer substitution for protein design.
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- Journal of Computational Chemistry, 2007, v. 28, n. 8, p. 1336, doi. 10.1002/jcc.20626
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- Article
Computer-based redesign of a protein folding pathway.
- Published in:
- Nature Structural Biology, 2001, v. 8, n. 7, p. 602, doi. 10.1038/89638
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- Article
A comparison of successful and failed protein interface designs highlights the challenges of designing buried hydrogen bonds.
- Published in:
- Protein Science: A Publication of the Protein Society, 2013, v. 22, n. 1, p. 74, doi. 10.1002/pro.2187
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- Article
Crystal structures and increased stabilization of the protein G variants with switched folding pathways NuG1 and NuG2.
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- Protein Science: A Publication of the Protein Society, 2002, v. 11, n. 12, p. 2924, doi. 10.1110/ps.0216902
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- Publication type:
- Article
Global analysis of the thermal and chemical denaturation of the N-terminal domain of the ribosomal protein L9 in H<sub>2</sub>O and D<sub>2</sub>O. Determination of the thermodynamic parameters, Δ H°, Δ S°, and Δ C°<sub>p</sub>, and evaluation of solvent isotope effects
- Published in:
- Protein Science: A Publication of the Protein Society, 1998, v. 7, n. 11, p. 2405, doi. 10.1002/pro.5560071118
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- Article
Invariant point message passing for protein side chain packing.
- Published in:
- Proteins, 2024, v. 92, n. 10, p. 1220, doi. 10.1002/prot.26705
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- Article
Perturbing the energy landscape for improved packing during computational protein design.
- Published in:
- Proteins, 2021, v. 89, n. 4, p. 436, doi. 10.1002/prot.26030
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- Publication type:
- Article
A biosensor generated via high-throughput screening quantifies cell edge Src dynamics.
- Published in:
- Nature Chemical Biology, 2012, v. 8, n. 8, p. 737, doi. 10.1038/nchembio0812-737d
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- Publication type:
- Article
A biosensor generated via high-throughput screening quantifies cell edge Src dynamics.
- Published in:
- Nature Chemical Biology, 2011, v. 7, n. 7, p. 437, doi. 10.1038/nchembio.585
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- Publication type:
- Article
Computational stabilization of T cell receptors allows pairing with antibodies to form bispecifics.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16231-7
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- Publication type:
- Article
Engineering a genetically encoded competitive inhibitor of the KEAP1–NRF2 interaction via structure-based design and phage display.
- Published in:
- PEDS: Protein Engineering, Design & Selection, 2016, v. 29, n. 1, p. 1, doi. 10.1093/protein/gzv055
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- Publication type:
- Article
A structural bioinformatics approach for identifying proteins predisposed to bind linear epitopes on pre-selected target proteins.
- Published in:
- PEDS: Protein Engineering, Design & Selection, 2013, v. 26, n. 4, p. 283, doi. 10.1093/protein/gzs108
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- Publication type:
- Article
De novo design of stable proteins that efficaciously inhibit oncogenic G proteins.
- Published in:
- Protein Science: A Publication of the Protein Society, 2023, v. 32, n. 8, p. 1, doi. 10.1002/pro.4713
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- Article
Design of a protease‐activated PD‐L1 inhibitor.
- Published in:
- Protein Science: A Publication of the Protein Society, 2023, v. 32, n. 3, p. 1, doi. 10.1002/pro.4578
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- Article
Stabilizing proteins, simplified: A Rosetta‐based webtool for predicting favorable mutations.
- Published in:
- Protein Science: A Publication of the Protein Society, 2022, v. 31, n. 10, p. 1, doi. 10.1002/pro.4428
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- Article
AlphaFold accurately predicts distinct conformations based on the oligomeric state of a de novo designed protein.
- Published in:
- Protein Science: A Publication of the Protein Society, 2022, v. 31, n. 7, p. 1, doi. 10.1002/pro.4368
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- Publication type:
- Article
Boosting protein stability with the computational design of β-sheet surfaces.
- Published in:
- Protein Science: A Publication of the Protein Society, 2016, v. 25, n. 3, p. 702, doi. 10.1002/pro.2869
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- Publication type:
- Article
Computational de novo design of a four-helix bundle protein- DND_4 HB.
- Published in:
- Protein Science: A Publication of the Protein Society, 2015, v. 24, n. 4, p. 434, doi. 10.1002/pro.2577
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- Publication type:
- Article