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Apelin inhibition prevents resistance and metastasis associated with anti‐angiogenic therapy.
Published in:
EMBO Molecular Medicine, 2019, v. 11, n. 8, p. N.PAG, doi. 10.15252/emmm.201809266
By:
- Uribesalgo, Iris;
- Hoffmann, David;
- Zhang, Yin;
- Kavirayani, Anoop;
- Lazovic, Jelena;
- Berta, Judit;
- Novatchkova, Maria;
- Pai, Tsung‐Pin;
- Wimmer, Reiner A;
- László, Viktória;
- Schramek, Daniel;
- Karim, Rezaul;
- Tortola, Luigi;
- Deswal, Sumit;
- Haas, Lisa;
- Zuber, Johannes;
- Szűcs, Miklós;
- Kuba, Keiji;
- Dome, Balazs;
- Cao, Yihai
Publication type:
Article
GALLBLADDER CARCINOMA IN AN ASYMPTOMATIC BILIARY TYPHOID CARRIER: REPORT OF A CASE.
Published in:
American Journal of Gastroenterology (Springer Nature), 1998, v. 93, n. 4, p. 656, doi. 10.1111/j.1572-0241.1998.188_b.x
By:
- Kuba, Keiji;
- Yamaguchi, Koji;
- Nishiyama, Kenichi;
- Noshiro, Hirokazu;
- Shimizu, Shuji;
- Chijiiwa, Kazuo;
- Tanaka, Masao
Publication type:
Article
The CCR4–NOT Deadenylase Complex Maintains Adipocyte Identity.
Published in:
International Journal of Molecular Sciences, 2019, v. 20, n. 21, p. 5274, doi. 10.3390/ijms20215274
By:
- Takahashi, Akinori;
- Takaoka, Shohei;
- Kobori, Shungo;
- Yamaguchi, Tomokazu;
- Ferwati, Sara;
- Kuba, Keiji;
- Yamamoto, Tadashi;
- Suzuki, Toru
Publication type:
Article
Loss of Apelin Augments Angiotensin II-Induced Cardiac Dysfunction and Pathological Remodeling.
Published in:
International Journal of Molecular Sciences, 2019, v. 20, n. 2, p. 239, doi. 10.3390/ijms20020239
By:
- Sato, Teruki;
- Kadowaki, Ayumi;
- Suzuki, Takashi;
- Ito, Hiroshi;
- Watanabe, Hiroyuki;
- Imai, Yumiko;
- Kuba, Keiji
Publication type:
Article
Apelin is a positive regulator of ACE2 in failing hearts.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 12, p. 5203, doi. 10.1172/JCI69608
By:
- Teruki Sato;
- Takashi Suzuki;
- Hiroyuki Watanabe;
- Ayumi Kadowaki;
- Akiyoshi Fukamizu;
- Peter P. Liu;
- Akinori Kimura;
- Hiroshi Ito;
- Penninger, Josef M.;
- Yumiko Imai;
- Keiji Kuba
Publication type:
Article
Angiotensin-Converting Enzyme 2 (ACE2) in the Pathogenesis of ARDS in COVID-19.
Published in:
Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.732690
By:
- Kuba, Keiji;
- Yamaguchi, Tomokazu;
- Penninger, Josef M.
Publication type:
Article
Squamous cell carcinoma‐derived G‐CSF promotes tumor growth and metastasis in mice through neutrophil recruitment and tumor cell proliferation, associated with poor prognosis of the patients.
Published in:
Genes to Cells, 2023, v. 28, n. 8, p. 573, doi. 10.1111/gtc.13051
By:
- Kemuriyama, Kohei;
- An, Jianbo;
- Motoyama, Satoru;
- Nagaki, Yushi;
- Yamaguchi, Tomokazu;
- Sato, Yusuke;
- Wakita, Akiyuki;
- Minamiya, Yoshihiro;
- Kuba, Keiji
Publication type:
Article
m<sup>6</sup>A demethylase ALKBH5 promotes proliferation of esophageal squamous cell carcinoma associated with poor prognosis.
Published in:
Genes to Cells, 2020, v. 25, n. 8, p. 547, doi. 10.1111/gtc.12792
By:
- Nagaki, Yushi;
- Motoyama, Satoru;
- Yamaguchi, Tomokazu;
- Hoshizaki, Midori;
- Sato, Yusuke;
- Sato, Teruki;
- Koizumi, Yukio;
- Wakita, Akiyuki;
- Kawakita, Yuta;
- Imai, Kazuhiro;
- Nanjo, Hiroshi;
- Watanabe, Hiroyuki;
- Imai, Yumiko;
- Minamiya, Yoshihiro;
- Kuba, Keiji
Publication type:
Article
A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus–induced lung injury.
Published in:
Nature Medicine, 2005, v. 11, n. 8, p. 875, doi. 10.1038/nm1267
By:
- Kuba, Keiji;
- Imai, Yumiko;
- Shuan Rao;
- Hong Gao;
- Feng Guo;
- Bin Guan;
- Yi Huan;
- Peng Yang;
- Yanli Zhang;
- Wei Deng;
- Linlin Bao;
- Binlin Zhang;
- Guang Liu;
- Zhong Wang;
- Chappell, Mark;
- Yanxin Liu;
- Dexian Zheng;
- Leibbrandt, Andreas;
- Wada, Teiji;
- Slutsky, Arthur S.
Publication type:
Article
Haploinsufficiency of Cnot3 Aggravates Acid-Induced Acute Lung Injury Likely Through Transcriptional and Post-Transcriptional Upregulation of Pro-Inflammatory Genes.
Published in:
Journal of Inflammation Research, 2024, v. 17, p. 5415, doi. 10.2147/JIR.S468612
By:
- Yamaguchi, Tomokazu;
- Ozawa, Ryo;
- Minato, Takafumi;
- Hoshizaki, Midori;
- Kammura, Yutaro;
- Okawara, Kazuma;
- Khalil, Yousef A;
- Nakamura, Masafumi;
- Yamaura, Ken;
- Fukuda, Masayuki;
- Imai, Yumiko;
- Kuba, Keiji
Publication type:
Article
PI3Kγ Protects from Myocardial Ischemia and Reperfusion Injury through a Kinase-Independent Pathway.
Published in:
PLoS ONE, 2010, v. 5, n. 2, p. 1, doi. 10.1371/journal.pone.0009350
By:
- Haubner, Bernhard J.;
- Neely, G. Gregory;
- Voelkl, Jakob G. J.;
- Damilano, Federico;
- Kuba, Keiji;
- Imai, Yumiko;
- Komnenovic, Vukoslav;
- Mayr, Agnes;
- Pachinger, Otmar;
- Hirsch, Emilio;
- Penninger, Josef M.;
- Metzler, Bernhard
Publication type:
Article
Losartan inhibits LPS-induced inflammatory signaling through a PPARγ-dependent mechanism in human THP-1 macrophages.
Published in:
Hypertension Research, 2010, v. 33, n. 8, p. 831, doi. 10.1038/hr.2010.79
By:
- An, Jianbo;
- Nakajima, Toshiaki;
- Kuba, Keiji;
- Kimura, Akinori
Publication type:
Article
Lessons from SARS: control of acute lung failure by the SARS receptor ACE2.
Published in:
Journal of Molecular Medicine, 2006, v. 84, n. 10, p. 814, doi. 10.1007/s00109-006-0094-9
By:
- Kuba, Keiji;
- Imai, Yumiko;
- Shuan Rao;
- Chengyu Jiang;
- Penninger, Josef
Publication type:
Article
ELABELA-APJ axis protects from pressure overload heart failure and angiotensin II-induced cardiac damage.
Published in:
Cardiovascular Research, 2017, v. 113, n. 7, p. 760, doi. 10.1093/cvr/cvx061
By:
- Teruki Sato;
- Sato, Chitose;
- Ayumi Kadowaki;
- Hiroyuki Watanabe;
- Lena Ho;
- Junji Ishida;
- Tomokazu Yamaguchi;
- Akinori Kimura;
- Akiyoshi Fukamizu;
- Penninger, Josef M.;
- Reversade, Bruno;
- Hiroshi Ito;
- Yumiko Imai;
- Keiji Kuba
Publication type:
Article
Nuclear accumulation of androgen receptor in gender difference of dilated cardiomyopathy due to lamin A/C mutations.
Published in:
Cardiovascular Research, 2013, v. 99, n. 3, p. 382, doi. 10.1093/cvr/cvt106
By:
- Arimura, Takuro;
- Onoue, Kenji;
- Takahashi-Tanaka, Yumiko;
- Ishikawa, Taisuke;
- Kuwahara, Masayoshi;
- Setou, Mitsutoshi;
- Shigenobu, Shuji;
- Yamaguchi, Katsushi;
- Bertrand, Anne T.;
- Machida, Noboru;
- Takayama, Kazumi;
- Fukusato, Masayuki;
- Tanaka, Ryo;
- Somekawa, Satoshi;
- Nakano, Tomoya;
- Yamane, Yoshihisa;
- Kuba, Keiji;
- Imai, Yumiko;
- Saito, Yoshihiko;
- Bonne, Gisèle
Publication type:
Article
Evaluation of Lecithinized Superoxide Dismutase for the Prevention of Acute Respiratory Distress Syndrome in Animal Models.
Published in:
American Journal of Respiratory Cell & Molecular Biology, 2017, v. 56, n. 2, p. 179, doi. 10.1165/rcmb.2016-0158OC
By:
- Ken-ichiro Tanaka;
- Fumiya Tamura;
- Toshifumi Sugizaki;
- Masahiro Kawahara;
- Keiji Kuba;
- Yumiko Imai;
- Tohru Mizushima
Publication type:
Article
Genome‐Scale CRISPR/Cas9 Screening Reveals Squalene Epoxidase as a Susceptibility Factor for Cytotoxicity of Malformin A1.
Published in:
ChemBioChem, 2019, v. 20, n. 12, p. 1563, doi. 10.1002/cbic.201800769
By:
- Koizumi, Yukio;
- Fukushima, Jun;
- Kobayashi, Yayoi;
- Kadowaki, Ayumi;
- Natsui, Miyuki;
- Yamaguchi, Tomokazu;
- Imai, Yumiko;
- Sugiyama, Toshihiro;
- Kuba, Keiji
Publication type:
Article
Incomplete antiviral treatment may induce longer durations of viral shedding during SARS-CoV-2 infection.
Published in:
Life Science Alliance, 2021, v. 4, n. 10, p. 1, doi. 10.26508/lsa.202101049
By:
- Kwang Su Kim;
- Shoya Iwanami;
- Takafumi Oda;
- Yasuhisa Fujita;
- Keiji Kuba;
- Taiga Miyazaki;
- Keisuke Ejima;
- Shingo Iwami
Publication type:
Article
Inhibition of tumor growth and invasion by a four-kringle antagonist (HGF/NK4) for hepatocyte growth factor.
Published in:
Oncogene, 1998, v. 17, n. 23, p. 3045, doi. 10.1038/sj.onc.1202231
By:
- Date, Kazuhiko;
- Matsumoto, Kunio;
- Kuba, Keiji;
- Shimura, Hideo;
- Tanaka, Masao;
- Nakamura, Toshikazu
Publication type:
Article
Eosinophils promote corneal wound healing via the 12/15-lipoxygenase pathway.
Published in:
FASEB Journal, 2020, v. 34, n. 9, p. 12492, doi. 10.1096/fj.202000483R
By:
- Mamoru Ogawa;
- Tomoaki Ishihara;
- Yosuke Isobe;
- Taiga Kato;
- Keiji Kuba;
- Yumiko Imai;
- Yuichi Uchino;
- Kazuo Tsubota;
- Makoto Arita
Publication type:
Article
Cationic nanoparticles directly bind angiotensin-converting enzyme 2 and induce acute lung injury in mice.
Published in:
Particle & Fibre Toxicology, 2015, v. 12, n. 1, p. 1, doi. 10.1186/s12989-015-0080-x
By:
- Yang Sun;
- Feng Guo;
- Zhen Zou;
- Chenggang Li;
- Xiaoxu Hong;
- Yan Zhao;
- Chenxuan Wang;
- Hongliang Wang;
- Haolin Liu;
- Peng Yang;
- Zongsheng Han;
- Kangtai Liu;
- Keiji Kuba;
- Bin Song;
- Jinming Gao;
- Ziyao Mo;
- Dangsheng Li;
- Bo Li;
- Qihan Li;
- Nanshan Zhong
Publication type:
Article
Cationic nanoparticles directly bind angiotensin-converting enzyme 2 and induce acute lung injury in mice.
Published in:
Particle & Fibre Toxicology, 2015, v. 12, n. 1, p. 1, doi. 10.1186/s12989-015-0080-x
By:
- Yang Sun;
- Feng Guo;
- Zhen Zou;
- Chenggang Li;
- Xiaoxu Hong;
- Yan Zhao;
- Chenxuan Wang;
- Hongliang Wang;
- Haolin Liu;
- Peng Yang;
- Zongsheng Han;
- Kangtai Liu;
- Keiji Kuba;
- Bin Song;
- Jinming Gao;
- Ziyao Mo;
- Dangsheng Li;
- Bo Li;
- Qihan Li;
- Nanshan Zhong
Publication type:
Article
CXCL10-CXCR3 Enhances the Development of Neutrophil-mediated Fulminant Lung Injury of Viral and Nonviral Origin.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2013, v. 187, n. 1, p. 65, doi. 10.1164/rccm.201203-0508OC
By:
- Akihiko Ichikawa;
- Keiji Kuba;
- Masayuki Morita;
- Shinsuke Chida;
- Hiroyuki Tezuka;
- Hiromitsu Hara;
- Takehiko Sasaki;
- Toshiaki Ohteki;
- Ranieri, V. Marco;
- dos Santos, Claudia C.;
- Yoshihiro Kawaoka;
- Shizuo Akira;
- Luster, Andrew D.;
- Bao Lu;
- Penninger, Josef M.;
- Uhlig, Stefan;
- Slutsky, Arthur S.;
- Yumiko Imai
Publication type:
Article
Angiotensin-converting enzyme 2 protects from severe acute lung failure.
Published in:
Nature, 2005, v. 436, n. 7047, p. 112, doi. 10.1038/nature03712
By:
- Imai, Yumiko;
- Kuba, Keiji;
- Shuan Rao;
- Yi Huan;
- Feng Guo;
- Bin Guan;
- Peng Yang;
- Renu Sarao;
- Wada, Teiji;
- Howard Leong-Poi;
- Crackower, Michael A.;
- Fukamizu, Akiyoshi;
- Chi-Chung Hui;
- Hein, Lutz;
- Stefan Uhlig;
- Slutsky, Arthur S.;
- Chengyu Jiang;
- Penninger, Josef M.
Publication type:
Article
Clonal hematopoiesis in adult pure red cell aplasia.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-81890-5
By:
- Fujishima, Naohito;
- Kohmaru, Junki;
- Koyota, Souichi;
- Kuba, Keiji;
- Saga, Tomoo;
- Omokawa, Ayumi;
- Moritoki, Yuki;
- Ueki, Shigeharu;
- Ishida, Fumihiro;
- Nakao, Shinji;
- Matsuda, Akira;
- Ohta, Akiko;
- Tohyama, Kaoru;
- Yamasaki, Hiroshi;
- Usuki, Kensuke;
- Nakashima, Yasuhiro;
- Sato, Shinya;
- Miyazaki, Yasushi;
- Nannya, Yasuhito;
- Ogawa, Seishi
Publication type:
Article
ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation.
Published in:
Nature, 2012, v. 487, n. 7408, p. 477, doi. 10.1038/nature11228
By:
- Hashimoto, Tatsuo;
- Perlot, Thomas;
- Rehman, Ateequr;
- Trichereau, Jean;
- Ishiguro, Hiroaki;
- Paolino, Magdalena;
- Sigl, Verena;
- Hanada, Toshikatsu;
- Hanada, Reiko;
- Lipinski, Simone;
- Wild, Birgit;
- Camargo, Simone M. R.;
- Singer, Dustin;
- Richter, Andreas;
- Kuba, Keiji;
- Fukamizu, Akiyoshi;
- Schreiber, Stefan;
- Clevers, Hans;
- Verrey, Francois;
- Rosenstiel, Philip
Publication type:
Article
The discovery of angiotensin-converting enzyme 2 and its role in acute lung injury in mice.
Published in:
Experimental Physiology, 2008, v. 93, n. 5, p. 543, doi. 10.1113/expphysiol.2007.040048
By:
- Imai, Yumiko;
- Kuba, Keiji;
- Penninger, Josef M.
Publication type:
Article
Blockade of histamine receptor H1 augments immune checkpoint therapy by enhancing MHC-I expression in pancreatic cancer cells.
Published in:
Journal of Experimental & Clinical Cancer Research (17569966), 2024, v. 43, n. 1, p. 1, doi. 10.1186/s13046-024-03060-5
By:
- Zhong, PingShan;
- Nakata, Kohei;
- Oyama, Koki;
- Higashijima, Nobuhiro;
- Sagara, Akiko;
- Date, Satomi;
- Luo, HaiZhen;
- Hayashi, Masataka;
- Kubo, Akihiro;
- Wu, ChenYi;
- He, Shan;
- Yamamoto, Takeo;
- Koikawa, Kazuhiro;
- Iwamoto, Chika;
- Abe, Toshiya;
- Ikenaga, Naoki;
- Ohuchida, Kenoki;
- Morisaki, Takashi;
- Oda, Yoshinao;
- Kuba, Keiji
Publication type:
Article
ACE2-like enzyme B38-CAP suppresses abdominal sepsis and severe acute lung injury.
Published in:
PLoS ONE, 2022, v. 17, n. 7, p. 1, doi. 10.1371/journal.pone.0270920
By:
- Minato, Takafumi;
- Yamaguchi, Tomokazu;
- Hoshizaki, Midori;
- Nirasawa, Satoru;
- An, Jianbo;
- Takahashi, Saori;
- Penninger, Josef M.;
- Imai, Yumiko;
- Kuba, Keiji
Publication type:
Article
The role of ACE2 in pulmonary diseases--relevance for the nephrologist.
Published in:
Nephrology Dialysis Transplantation, 2009, v. 24, n. 5, p. 1362, doi. 10.1093/ndt/gfp065
By:
- Gavin Y. Oudit;
- Yumiko Imai;
- Keiji Kuba;
- James W. Scholey;
- Josef M. Penninger
Publication type:
Article
Systemic NK4 gene therapy inhibits tumor growth and metastasis of melanoma and lung carcinoma in syngeneic mouse tumor models.
Published in:
Cancer Science, 2009, v. 100, n. 7, p. 1351, doi. 10.1111/j.1349-7006.2009.01184.x
By:
- Kishi, Yuko;
- Kuba, Keiji;
- Nakamura, Takahiro;
- Wen, Jinhua;
- Suzuki, Yoshinori;
- Mizuno, Shinya;
- Nukiwa, Toshihiro;
- Matsumoto, Kunio;
- Nakamura, Toshikazu
Publication type:
Article
Apelin Treatment Increases Complete Fatty Acid Oxidation, Mitochondrial Oxidative Capacity, and Biogenesis in Muscle of Insulin-Resistant Mice.
Published in:
Diabetes, 2012, v. 61, n. 2, p. 310, doi. 10.2337/db11-0100
By:
- Attané, Camille;
- Foussal, Camille;
- Le Gonidec, Sophie;
- Benani, Alexandre;
- Daviaud, Danièle;
- Wanecq, Estelle;
- Guzmán-Ruiz, Rocío;
- Dray, Cédric;
- Bezaire, Veronic;
- Rancoule, Chloé;
- Kuba, Keiji;
- Ruiz-Gayo, Mariano;
- Levade, Thierry;
- Penninger, Josef;
- Burcelin, Rémy;
- Pénicaud, Luc;
- Valet, Philippe;
- Castan-Laurell, Isabelle
Publication type:
Article

Found: 32