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A phase I/Ib study of OTSGC-A24 combined peptide vaccine in advanced gastric cancer.
Published in:
2018
By:
- Sundar, Raghav;
- Rha, Sun Young;
- Yamaue, Hiroki;
- Katsuda, Masahiro;
- Kono, Koji;
- Kim, Hyo Song;
- Kim, Chan;
- Mimura, Kousaku;
- Kua, Ley-Fang;
- Yong, Wei Peng
Publication type:
journal article
Upregulation of thioredoxin-1 in activated human NK cells confers increased tolerance to oxidative stress.
Published in:
Cancer Immunology, Immunotherapy, 2017, v. 66, n. 5, p. 605, doi. 10.1007/s00262-017-1969-z
By:
- Mimura, Kousaku;
- Kua, Ley-Fang;
- Shimasaki, Noriko;
- Shiraishi, Kensuke;
- Nakajima, Shotaro;
- Siang, Lim;
- Shabbir, Asim;
- So, Jimmy;
- Yong, Wei-Peng;
- Kono, Koji
Publication type:
Article
Phospho-STAT1 expression as a potential biomarker for anti-PD-1/anti-PD-L1 immunotherapy for breast cancer.
Published in:
International Journal of Oncology, 2019, v. 54, n. 6, p. 2030, doi. 10.3892/ijo.2019.4779
By:
- Nakayama, Yuko;
- Mimura, Kosaku;
- Tamaki, Tomoaki;
- Shiraishi, Kensuke;
- Kua, Ley-Fang;
- Koh, Vivien;
- Ohmori, Masato;
- Kimura, Ayako;
- Inoue, Shingo;
- Okayama, Hirokazu;
- Suzuki, Yoshiyuki;
- Nakazawa, Tadao;
- Ichikawa, Daisuke;
- Kono, Koji
Publication type:
Article
Therapeutic potential of highly cytotoxic natural killer cells for gastric cancer.
Published in:
International Journal of Cancer, 2014, v. 135, n. 6, p. 1390, doi. 10.1002/ijc.28780
By:
- Mimura, Kousaku;
- Kamiya, Takahiro;
- Shiraishi, Kensuke;
- Kua, Ley‐Fang;
- Shabbir, Asim;
- So, Jimmy;
- Yong, Wei‐Peng;
- Suzuki, Yoshiyuki;
- Yoshimoto, Yuya;
- Nakano, Takashi;
- Fujii, Hideki;
- Campana, Dario;
- Kono, Koji
Publication type:
Article
Clinical relevance of PD-1 positive CD8 T-cells in gastric cancer.
Published in:
Gastric Cancer, 2023, v. 26, n. 3, p. 393, doi. 10.1007/s10120-023-01364-7
By:
- Choo, Joan;
- Kua, Ley Fang;
- Soe, Mu Yar;
- Asuncion, Bernadette Reyna;
- Tan, Benjamin Kye Jyn;
- Teo, Chong Boon;
- Tay, Ryan Yong Kiat;
- So, Jimmy;
- Shabbir, Asim;
- Guowei, Kim;
- Tan, Hon Lyn;
- Chan, Gloria;
- Ma, Haoran;
- Ramachandran, Gokula Krishnan;
- Lum, Jeffrey H. Y.;
- Chee, Cheng Ean;
- Sridharan, Sriram;
- Tan, Patrick;
- Sundar, Raghav;
- Yong, Wei Peng
Publication type:
Article
Combined inhibition of PD-1/PD-L1, Lag-3, and Tim-3 axes augments antitumor immunity in gastric cancer–T cell coculture models.
Published in:
Gastric Cancer, 2021, v. 24, n. 3, p. 611, doi. 10.1007/s10120-020-01151-8
By:
- Mimura, Kosaku;
- Kua, Ley-Fang;
- Xiao, Jin-Fen;
- Asuncion, Bernadette Reyna;
- Nakayama, Yuko;
- Syn, Nicholas;
- Fazreen, Zul;
- Soong, Richie;
- Kono, Koji;
- Yong, Wei-Peng
Publication type:
Article
Immune suppression caused by PD-L2 expression on tumor cells in gastric cancer.
Published in:
Gastric Cancer, 2020, v. 23, n. 6, p. 961, doi. 10.1007/s10120-020-01079-z
By:
- Nakayama, Yuko;
- Mimura, Kosaku;
- Kua, Ley-Fang;
- Okayama, Hirokazu;
- Min, Aung Kyi Thar;
- Saito, Katsuharu;
- Hanayama, Hiroyuki;
- Watanabe, Yohei;
- Saito, Motonobu;
- Momma, Tomoyuki;
- Saze, Zenichiro;
- Ohki, Shinji;
- Suzuki, Yoshiyuki;
- Ichikawa, Daisuke;
- Yong, Wei-Peng;
- Kono, Koji
Publication type:
Article
Inhibition of MMP activity can restore NKG2D ligand expression in gastric cancer, leading to improved NK cell susceptibility.
Published in:
2016
By:
- Shiraishi, Kensuke;
- Mimura, Kousaku;
- Kua, Ley-Fang;
- Koh, Vivien;
- Siang, Lim;
- Nakajima, Shotaro;
- Fujii, Hideki;
- Shabbir, Asim;
- Yong, Wei-Peng;
- So, Jimmy;
- Takenoshita, Seiichi;
- Kono, Koji;
- Siang, Lim Kee
Publication type:
journal article
PD‐L1 expression is mainly regulated by interferon gamma associated with JAK‐STAT pathway in gastric cancer.
Published in:
Cancer Science, 2018, v. 109, n. 1, p. 43, doi. 10.1111/cas.13424
By:
- Mimura, Kousaku;
- Teh, Jun Liang;
- Okayama, Hirokazu;
- Shiraishi, Kensuke;
- Kua, Ley‐Fang;
- Koh, Vivien;
- Smoot, Duane T.;
- Ashktorab, Hassan;
- Oike, Takahiro;
- Suzuki, Yoshiyuki;
- Fazreen, Zul;
- Asuncion, Bernadette R.;
- Shabbir, Asim;
- Yong, Wei‐Peng;
- So, Jimmy;
- Soong, Richie;
- Kono, Koji
Publication type:
Article
Inhibition of mitogen-activated protein kinase pathway can induce upregulation of human leukocyte antigen class I without PD-L1-upregulation in contrast to interferon-γ treatment.
Published in:
Cancer Science, 2014, v. 105, n. 10, p. 1236, doi. 10.1111/cas.12503
By:
- Mimura, Kousaku;
- Kua, Ley‐Fang;
- Shiraishi, Kensuke;
- Kee Siang, Lim;
- Shabbir, Asim;
- Komachi, Mayumi;
- Suzuki, Yoshiyuki;
- Nakano, Takashi;
- Yong, Wei‐Peng;
- So, Jimmy;
- Kono, Koji
Publication type:
Article

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