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Differential effects of glucose-dependent insulinotropic polypeptide receptor/glucagon-like peptide-1 receptor heteromerization on cell signaling when expressed in HEK-293 cells.
Published in:
Pharmacology Research & Perspectives, 2022, v. 10, n. 5, p. 1, doi. 10.1002/prp2.1013
By:
- Al Zaid, Bashaier;
- Chacko, Siby;
- Ezeamuzie, Charles Ifeamalume;
- Bünemann, Moritz;
- Krasel, Cornelius;
- Karimian, Tina;
- Lanzerstorfer, Peter;
- Al-Sabah, Suleiman
Publication type:
Article
β-arrestin1 and 2 exhibit distinct phosphorylation-dependent conformations when coupling to the same GPCR in living cells.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33307-8
By:
- Haider, Raphael S.;
- Matthees, Edda S. F.;
- Drube, Julia;
- Reichel, Mona;
- Zabel, Ulrike;
- Inoue, Asuka;
- Chevigné, Andy;
- Krasel, Cornelius;
- Deupi, Xavier;
- Hoffmann, Carsten
Publication type:
Article
Correction: Al-Zamel, N., et al. A Dual GLP-1/GIP Receptor agonist Does Not Antagonize Glucagon at Its Receptor but May Act as a Biased agonist at the GLP-1 Receptor. Int. J. Mol. Sci. 2019, 20, 3532.
Published in:
2020
By:
- Al-Zamel, Noura;
- Al-Sabah, Suleiman;
- Luqmani, Yunus;
- Adi, Lobna;
- Chacko, Siby;
- Schneider, Tom Dario;
- Krasel, Cornelius
Publication type:
Correction Notice
A Dual GLP-1/GIP Receptor Agonist Does Not Antagonize Glucagon at Its Receptor but May Act as a Biased Agonist at the GLP-1 Receptor.
Published in:
International Journal of Molecular Sciences, 2019, v. 20, n. 14, p. 3532, doi. 10.3390/ijms20143532
By:
- Al-Zamel, Noura;
- Al-Sabah, Suleiman;
- Luqmani, Yunus;
- Adi, Lobna;
- Chacko, Siby;
- Schneider, Tom Dario;
- Krasel, Cornelius
Publication type:
Article
Identification of key phosphorylation sites in PTH1R that determine arrestin3 binding and fine-tune receptor signaling.
Published in:
Biochemical Journal, 2016, v. 473, n. 22, p. 4173, doi. 10.1042/BCJ20160740
By:
- Zindel, Diana;
- Engel, Sandra;
- Bottrill, Andrew R.;
- Pin, Jean-Philippe;
- Prézeau, Laurent;
- Tobin, Andrew B.;
- Bünemann, Moritz;
- Krasel, Cornelius;
- Butcher, Adrian J.
Publication type:
Article
Evidence that GABA ρ subunits contribute to functional ionotropic GABA receptors in mouse cerebellar Purkinje cells.
Published in:
Journal of Physiology, 2006, v. 577, n. 1, p. 127, doi. 10.1113/jphysiol.2006.112482
By:
- Harvey, Victoria L.;
- Duguid, Ian C.;
- Krasel, Cornelius;
- Stephens, Gary J.
Publication type:
Article
Multisite phosphorylation is required for sustained interaction with GRKs and arrestins during rapid μ-opioid receptor desensitization.
Published in:
Science Signaling, 2018, v. 11, n. 539, p. 1, doi. 10.1126/scisignal.aas9609
By:
- Miess, Elke;
- Gondin, Arisbel B.;
- Yousuf, Arsalan;
- Steinborn, Ralph;
- Mösslein, Nadja;
- Yang, Yunshi;
- Göldner, Martin;
- Ruland, Julia G.;
- Bünemann, Moritz;
- Krasel, Cornelius;
- Christie, MacDonald J.;
- Halls, Michelle L.;
- Schulz, Stefan;
- Canals, Meritxell
Publication type:
Article
Measurement of the millisecond activation switch of G protein-coupled receptors in living cells.
Published in:
Nature Biotechnology, 2003, v. 21, n. 7, p. 807, doi. 10.1038/nbt838
By:
- Vilardaga, Jean-Pierre;
- Bunemann, Moritz;
- Krasel, Cornelius;
- Castro, Marian;
- Lohse, Martin J
Publication type:
Article
The GIP Receptor Displays Higher Basal Activity than the GLP-1 Receptor but Does Not Recruit GRK2 or Arrestin3 Effectively.
Published in:
PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0106890
By:
- Al-Sabah, Suleiman;
- Al-Fulaij, Munya;
- Shaaban, Ghina;
- Ahmed, Hanadi A.;
- Mann, Rosalind J.;
- Donnelly, Dan;
- Bünemann, Moritz;
- Krasel, Cornelius
Publication type:
Article
FRET-Based Detection of M1 Muscarinic Acetylcholine Receptor Activation by Orthosteric and Allosteric Agonists.
Published in:
PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0029946
By:
- Markovic, Danijela;
- Holdich, Jonathan;
- Al-Sabah, Suleiman;
- Mistry, Rajendra;
- Krasel, Cornelius;
- Mahaut-Smith, Martyn P.;
- Challiss, R. A. John
Publication type:
Article
Disentangling bias between Gq, GRK2, and arrestin3 recruitment to the M3 muscarinic acetylcholine receptor.
Published in:
eLife, 2021, p. 1, doi. 10.7554/eLife.58442
By:
- Flöser, Anja;
- Becker, Katharina;
- Kostenis, Evi;
- König, Gabriele;
- Krasel, Cornelius;
- Kolb, Peter;
- Bünemann, Moritz
Publication type:
Article
The Effect of Cell Surface Expression and Linker Sequence on the Recruitment of Arrestin to the GIP Receptor.
Published in:
Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.01271
By:
- Al-Sabah, Suleiman;
- Adi, Lobna;
- Bünemann, Moritz;
- Krasel, Cornelius
Publication type:
Article
Residency time of agonists does not affect the stability of GPCR–arrestin complexes.
Published in:
British Journal of Pharmacology, 2022, v. 179, n. 16, p. 4107, doi. 10.1111/bph.15846
By:
- Mösslein, Nadja;
- Pohle, Lisa‐Marie Geertje;
- Fuss, Anneke;
- Bünemann, Moritz;
- Krasel, Cornelius
Publication type:
Article
Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists.
Published in:
Science Signaling, 2020, v. 13, n. 625, p. 1, doi. 10.1126/scisignal.aaz3140
By:
- Gillis, Alexander;
- Gondin, Arisbel B.;
- Kliewer, Andrea;
- Sanchez, Julie;
- Lim, Herman D.;
- Alamein, Claudia;
- Manandhar, Preeti;
- Santiago, Marina;
- Fritzwanker, Sebastian;
- Schmidel, Frank;
- Katte, Timothy A.;
- Reekie, Tristan;
- Grimsey, Natasha L.;
- Kassiou, Michael;
- Kellam, Barrie;
- Krasel, Cornelius;
- Halls, Michelle L.;
- Connor, Mark;
- Lane, J. Robert;
- Schulz, Stefan
Publication type:
Article
Opioid receptors: single molecule studies shed light on mechanisms of efficacy.
Published in:
Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01920-2
By:
- Krasel, Cornelius;
- Bünemann, Moritz
Publication type:
Article
Potassium channel TASK-5 forms functional heterodimers with TASK-1 and TASK-3 to break its silence.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-51288-8
By:
- Rinné, Susanne;
- Schick, Florian;
- Vowinkel, Kirsty;
- Schütte, Sven;
- Krasel, Cornelius;
- Kauferstein, Silke;
- Schäfer, Martin K.-H.;
- Kiper, Aytug K.;
- Müller, Thomas;
- Decher, Niels
Publication type:
Article
G-protein-coupled receptor kinases.
Published in:
1996
By:
- Lohse, Martin J.;
- Krasel, Cornelius;
- Winstel, Rainer;
- Mayor Jr., Federico;
- Lohse, M J;
- Krasel, C;
- Winstel, R;
- Mayor, F Jr
Publication type:
journal article

Found: 17

Differential effects of glucose-dependent insulinotropic polypeptide receptor/glucagon-like peptide-1 receptor heteromerization on cell signaling when expressed in HEK-293 cells.

β-arrestin1 and 2 exhibit distinct phosphorylation-dependent conformations when coupling to the same GPCR in living cells.

Correction: Al-Zamel, N., et al. A Dual GLP-1/GIP Receptor agonist Does Not Antagonize Glucagon at Its Receptor but May Act as a Biased agonist at the GLP-1 Receptor. Int. J. Mol. Sci. 2019, 20, 3532.

A Dual GLP-1/GIP Receptor Agonist Does Not Antagonize Glucagon at Its Receptor but May Act as a Biased Agonist at the GLP-1 Receptor.

Identification of key phosphorylation sites in PTH1R that determine arrestin3 binding and fine-tune receptor signaling.

Evidence that GABA ρ subunits contribute to functional ionotropic GABA receptors in mouse cerebellar Purkinje cells.

Multisite phosphorylation is required for sustained interaction with GRKs and arrestins during rapid μ-opioid receptor desensitization.

Measurement of the millisecond activation switch of G protein-coupled receptors in living cells.

The GIP Receptor Displays Higher Basal Activity than the GLP-1 Receptor but Does Not Recruit GRK2 or Arrestin3 Effectively.

FRET-Based Detection of M<sub>1</sub> Muscarinic Acetylcholine Receptor Activation by Orthosteric and Allosteric Agonists.

Disentangling bias between G<sub>q</sub>, GRK2, and arrestin3 recruitment to the M<sub>3</sub> muscarinic acetylcholine receptor.

The Effect of Cell Surface Expression and Linker Sequence on the Recruitment of Arrestin to the GIP Receptor.

Residency time of agonists does not affect the stability of GPCR–arrestin complexes.

Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists.

Opioid receptors: single molecule studies shed light on mechanisms of efficacy.

Potassium channel TASK-5 forms functional heterodimers with TASK-1 and TASK-3 to break its silence.

G-protein-coupled receptor kinases.