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Modifications of Sarcoplasmic Reticulum Function Prevent Progression of Sarcomere-Linked Hypertrophic Cardiomyopathy Despite a Persistent Increase in Myofilament Calcium Response.
- Published in:
- Frontiers in Physiology, 2020, p. 1, doi. 10.3389/fphys.2020.00107
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- Publication type:
- Article
Myofilament Alterations Associated with Human R14del-Phospholamban Cardiomyopathy.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 3, p. 2675, doi. 10.3390/ijms24032675
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- Publication type:
- Article
Aberrant PLN-R14del Protein Interactions Intensify SERCA2a Inhibition, Driving Impaired Ca 2+ Handling and Arrhythmogenesis.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 13, p. 6947, doi. 10.3390/ijms23136947
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- Publication type:
- Article
The Cardioprotective PKA-Mediated Hsp20 Phosphorylation Modulates Protein Associations Regulating Cytoskeletal Dynamics.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 24, p. 9572, doi. 10.3390/ijms21249572
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- Publication type:
- Article
Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle.
- Published in:
- 2011
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- Publication type:
- journal article
Endoplasmic reticulum-mitochondria crosstalk in NIX-mediated murine cell death.
- Published in:
- 2009
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- Publication type:
- journal article
Junctin and the histidine-rich Ca<sup>2+</sup> binding protein: potential roles in heart failure and arrhythmogenesis.
- Published in:
- Journal of Physiology, 2009, v. 587, n. 13, p. 3125, doi. 10.1113/jphysiol.2009.172171
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- Publication type:
- Article
Phospholamban regulation of bladder contractility: evidence from gene-altered mouse models.
- Published in:
- Journal of Physiology, 2001, v. 535, n. 3, p. 867, doi. 10.1111/j.1469-7793.2001.00867.x
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- Publication type:
- Article
Is myosin phosphatase regulated in vivo by inhibitor-1? Evidence from inhibitor-1 knockout mice.
- Published in:
- Journal of Physiology, 2001, v. 534, n. 2, p. 357, doi. 10.1111/j.1469-7793.2001.00357.x
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- Publication type:
- Article
Hsp20-Engineered Mesenchymal Stem Cells Are Resistant to Oxidative Stress via Enhanced Activation of Akt and Increased Secretion of Growth Factors.
- Published in:
- Stem Cells, 2009, v. 27, n. 12, p. 3021, doi. 10.1002/stem.230
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- Publication type:
- Article
PKC-a regulates cardiac contractility and propensity toward heart failure.
- Published in:
- Nature Medicine, 2004, v. 10, n. 3, p. 248, doi. 10.1038/nm1000
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- Publication type:
- Article
Calcium: Phospholamban: a crucial regulator of cardiac contractility.
- Published in:
- Nature Reviews Molecular Cell Biology, 2003, v. 4, n. 7, p. 566, doi. 10.1038/nrm1151
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- Publication type:
- Article
Active Inhibitor-1 Maintains Protein Hyper-Phosphorylation in Aging Hearts and Halts Remodeling in Failing Hearts.
- Published in:
- PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0080717
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- Publication type:
- Article
Identification of a Protein Phosphatase-1/Phospholamban Complex That Is Regulated by cAMP-Dependent Phosphorylation.
- Published in:
- PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0080867
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- Publication type:
- Article
AAV-Mediated Knock-Down of HRC Exacerbates Transverse Aorta Constriction- Induced Heart Failure.
- Published in:
- PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0043282
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- Publication type:
- Article
Triadin/Junctin Double Null Mouse Reveals a Differential Role for Triadin and Junctin in Anchoring CASQ to the jSR and Regulating Ca<sup>2+</sup> Homeostasis.
- Published in:
- PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0039962
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- Publication type:
- Article
Hsp20 Functions as a Novel Cardiokine in Promoting Angiogenesis via Activation of VEGFR2.
- Published in:
- PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0032765
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- Publication type:
- Article
Phospholamban Gene Dosage Effects in Chemically Permeabilized Mouse Cardiac Muscle.
- Published in:
- Annals of the New York Academy of Sciences, 1998, v. 853, n. 1, p. 296, doi. 10.1111/j.1749-6632.1998.tb08283.x
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- Publication type:
- Article
Cardiac Responses to Calcium Sensitizers and Isoproterenol in Intact Guinea Pig Hearts: Effects on Cyclic AMP Levels, Protein Phosphorylation, Myoplasmic Calcium Concentration, and Left Ventricular Function.
- Published in:
- Annals of the New York Academy of Sciences, 1998, v. 853, n. 1, p. 316, doi. 10.1111/j.1749-6632.1998.tb08288.x
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- Publication type:
- Article
Introduction.
- Published in:
- Annals of the New York Academy of Sciences, 1998, v. 853, n. 1, p. xiii, doi. 10.1111/j.1749-6632.1998.tb08250.x
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- Publication type:
- Article
Phospholamban Ablation and Compensatory Responses in the Mammalian Heart <sup>a</sup>.
- Published in:
- Annals of the New York Academy of Sciences, 1998, v. 853, n. 1, p. 49, doi. 10.1111/j.1749-6632.1998.tb08256.x
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- Publication type:
- Article
The Human G147D-Protein Phosphatase 1 Inhibitor-1 Polymorphism Is Not Associated with Altered Clinical Characteristics in Heart Failure.
- Published in:
- Cardiology, 2009, v. 112, n. 3, p. 224, doi. 10.1159/000151240
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- Publication type:
- Article
Ablation of phospholamban rescues reperfusion arrhythmias but exacerbates myocardium infarction in hearts with Ca 2+ /calmodulin kinase II constitutive phosphorylation of ryanodine receptors.
- Published in:
- Cardiovascular Research, 2019, v. 115, n. 3, p. 556, doi. 10.1093/cvr/cvy213
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- Publication type:
- Article
Impaired calcium homeostasis is associated with sudden cardiac death and arrhythmias in a genetic equivalent mouse model of the human HRC-Ser96Ala variant.
- Published in:
- Cardiovascular Research, 2017, v. 113, n. 11, p. 1403, doi. 10.1093/cvr/cvx113
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- Publication type:
- Article
Ablation of HRC alleviates cardiac arrhythmia and improves abnormal Ca handling in CASQ2 knockout mice prone to CPVT.
- Published in:
- Cardiovascular Research, 2015, v. 108, n. 2, p. 299, doi. 10.1093/cvr/cvv222
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- Publication type:
- Article
A novel human R25C-phospholambanmutation is associated with super-inhibition of calcium cycling and ventricular arrhythmia.
- Published in:
- Cardiovascular Research, 2015, v. 107, n. 1, p. 164, doi. 10.1093/cvr/cvv127
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- Publication type:
- Article
Ablation of junctin or triadin is associated with increased cardiac injury following ischaemia/reperfusion.
- Published in:
- Cardiovascular Research, 2012, v. 94, n. 2, p. 333, doi. 10.1093/cvr/cvs119
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- Publication type:
- Article
Overexpression of histidine-rich Ca-binding protein protects against ischemia/reperfusion-induced cardiac injury
- Published in:
- Cardiovascular Research, 2007, v. 75, n. 3, p. 487, doi. 10.1016/j.cardiores.2007.04.005
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- Publication type:
- Article
CaMKII inhibition protects against necrosis and apoptosis in irreversible ischemia–reperfusion injury
- Published in:
- Cardiovascular Research, 2007, v. 73, n. 4, p. 689, doi. 10.1016/j.cardiores.2006.12.003
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- Publication type:
- Article
Phospholamban phosphorylation sites enhance the recovery of intracellular Ca<sup>2+</sup> after perfusion arrest in isolated, perfused mouse heart
- Published in:
- Cardiovascular Research, 2006, v. 70, n. 2, p. 335, doi. 10.1016/j.cardiores.2006.01.018
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- Publication type:
- Article
Role of phosphorylation of Thr<sup>17</sup> residue of phospholamban in mechanical recovery during hypercapnic acidosis
- Published in:
- Cardiovascular Research, 2005, v. 66, n. 1, p. 114, doi. 10.1016/j.cardiores.2004.12.028
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- Publication type:
- Article
Phospholamban gene ablation improves calcium transients but not cardiac function in a heart failure model
- Published in:
- Cardiovascular Research, 2004, v. 62, n. 3, p. 468, doi. 10.1016/j.cardiores.2004.02.006
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- Publication type:
- Article
Differential regulation of p38 mitogen-activated protein kinase mediates gender-dependent catecholamine-induced hypertrophy
- Published in:
- Cardiovascular Research, 2003, v. 57, n. 3, p. 704, doi. 10.1016/S0008-6363(02)00772-1
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- Publication type:
- Article
Combined phospholamban ablation and SERCA1a overexpression result in a new hyperdynamic cardiac state
- Published in:
- Cardiovascular Research, 2003, v. 57, n. 1, p. 71, doi. 10.1016/S0008-6363(02)00609-0
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- Publication type:
- Article
Structural and functional implications of the phospholamban hinge domain: impaired SR Ca<sup>2+</sup> uptake as a primary cause of heart failure
- Published in:
- Cardiovascular Research, 2002, v. 56, n. 2, p. 248, doi. 10.1016/S0008-6363(02)00541-2
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- Publication type:
- Article
Enhanced myocyte contractility and Ca<sup>2+</sup> handling in a calcineurin transgenic model of heart failure
- Published in:
- Cardiovascular Research, 2002, v. 54, n. 1, p. 105, doi. 10.1016/S0008-6363(02)00230-4
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- Publication type:
- Article
Hypertrophy and functional alterations in hyperdynamic phospholamban-knockout mouse hearts under chronic aortic stenosis
- Published in:
- Cardiovascular Research, 2002, v. 53, n. 2, p. 372, doi. 10.1016/S0008-6363(01)00487-4
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- Publication type:
- Article
THE ROLE OF CALMODULIN IN REGULATION OF CARDIAC SARCOPLASMIC RETICULUM PHOSPHORYLATION.
- Published in:
- Annals of the New York Academy of Sciences, 1980, v. 356, n. 1, p. 279, doi. 10.1111/j.1749-6632.1980.tb29618.x
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- Publication type:
- Article
The role of SERCA2a/PLN complex, Ca<sup>2+</sup> homeostasis, and anti-apoptotic proteins in determining cell fate.
- Published in:
- Pflügers Archiv: European Journal of Physiology, 2008, v. 457, n. 3, p. 687, doi. 10.1007/s00424-008-0506-5
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- Publication type:
- Article
Cardiac I-1c Overexpression With Reengineered AAV Improves Cardiac Function in Swine Ischemic Heart Failure.
- Published in:
- Molecular Therapy, 2014, v. 22, n. 12, p. 2038, doi. 10.1038/mt.2014.127
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- Publication type:
- Article
Probenecid treatment improves outcomes in a novel mouse model of peripartum cardiomyopathy.
- Published in:
- PLoS ONE, 2020, v. 15, n. 3, p. 1, doi. 10.1371/journal.pone.0230386
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- Publication type:
- Article
Scientists on the Spot: Calcium dynamics in heart function.
- Published in:
- Cardiovascular Research, 2020, v. 116, n. 7, p. e73, doi. 10.1093/cvr/cvaa031
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- Publication type:
- Article
A novel human S10F‐Hsp20 mutation induces lethal peripartum cardiomyopathy.
- Published in:
- Journal of Cellular & Molecular Medicine, 2018, v. 22, n. 8, p. 3911, doi. 10.1111/jcmm.13665
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- Publication type:
- Article
Regulation of cAMP homeostasis by the efflux protein MRP4 in cardiac myocytes.
- Published in:
- FASEB Journal, 2012, v. 26, n. 3, p. 1009, doi. 10.1096/fj.11-194027
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- Publication type:
- Article
Muscle lim protein isoform negatively regulates striated muscle actin dynamics and differentiation.
- Published in:
- FEBS Journal, 2014, v. 281, n. 14, p. 3261, doi. 10.1111/febs.12859
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- Publication type:
- Article
Up-regulation of micro- RNA765 in human failing hearts is associated with post-transcriptional regulation of protein phosphatase inhibitor-1 and depressed contractility.
- Published in:
- European Journal of Heart Failure, 2015, v. 17, n. 8, p. 782, doi. 10.1002/ejhf.323
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- Publication type:
- Article
A human polymorphism of protein phosphatase-1 inhibitor-1 is associated with attenuated contractile response of cardiomyocytes to β-adrenergic stimulation.
- Published in:
- FASEB Journal, 2008, v. 22, n. 6, p. 1790, doi. 10.1096/fj.07-097428
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- Publication type:
- Article
A Human Polymorphism of Protein Phosphatase 1 Inhibitor 1 is Associated With Attenuated Cardiac Contractile Responses to Beta-adrenergic Stimulation.
- Published in:
- FASEB Journal, 2007, v. 21, n. 6, p. A1256, doi. 10.1096/fasebj.21.6.a1256-a
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- Publication type:
- Article
Proteomic analysis of hyperdynamic mouse hearts with enhanced sarcoplasmic reticulum calcium cycling.
- Published in:
- FASEB Journal, 2004, v. 18, n. 14, p. 1725, doi. 10.1096/fj.04-2025fje
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- Publication type:
- Article
Overexpression of phospholamban in slow-twitch skeletal muscle is associated with depressed contractile function and muscle remodeling.
- Published in:
- FASEB Journal, 2004, v. 18, n. 9, p. 974, doi. 10.1096/fj.03-1058fje
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- Publication type:
- Article