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Whole-exome DNA sequence analysis of Brca2- and Trp53-deficient mouse mammary gland tumours.
Published in:
Journal of Pathology, 2015, v. 236, n. 2, p. 186, doi. 10.1002/path.4517
By:
- Francis, Jeffrey C;
- Melchor, Lorenzo;
- Campbell, James;
- Kendrick, Howard;
- Wei, Wenbin;
- Armisen‐Garrido, Javier;
- Assiotis, Ioannis;
- Chen, Lina;
- Kozarewa, Iwanka;
- Fenwick, Kerry;
- Swain, Amanda;
- Smalley, Matthew J;
- Lord, Christopher J;
- Ashworth, Alan
Publication type:
Article
Circadian clock components control daily growth activities by modulating cytokinin levels and cell division-associated gene expression in Populus trees.
Published in:
Plant, Cell & Environment, 2018, v. 41, n. 6, p. 1468, doi. 10.1111/pce.13185
By:
- Edwards, Kieron D.;
- Takata, Naoki;
- Johansson, Mikael;
- Jurca, Manuela;
- Novák, Ondřej;
- Hényková, Eva;
- Liverani, Silvia;
- Kozarewa, Iwanka;
- Strnad, Miroslav;
- Millar, Andrew J.;
- Ljung, Karin;
- Eriksson, Maria E.
Publication type:
Article
Genome-wide characterization reveals complex interplay between TP53 and TP63 in response to genotoxic stress.
Published in:
Nucleic Acids Research, 2014, v. 42, n. 10, p. 6270, doi. 10.1093/nar/gku299
By:
- McDade, Simon S.;
- Patel, Daksha;
- Moran, Michael;
- Campbell, James;
- Fenwick, Kerry;
- Kozarewa, Iwanka;
- Orr, Nicholas J.;
- Lord, Christopher J.;
- Ashworth, Alan A.;
- McCance, Dennis J.
Publication type:
Article
Genome-wide analysis of p63 binding sites identifies AP-2 factors as co-regulators of epidermal differentiation.
Published in:
Nucleic Acids Research, 2012, v. 40, n. 15, p. 7190, doi. 10.1093/nar/gks389
By:
- McDade, Simon S.;
- Henry, Alexandra E.;
- Pivato, Geraldine P.;
- Kozarewa, Iwanka;
- Mitsopoulos, Constantinos;
- Fenwick, Kerry;
- Assiotis, Ioannis;
- Hakas, Jarle;
- Zvelebil, Marketa;
- Orr, Nicholas;
- Lord, Christopher J.;
- Patel, Daksha;
- Ashworth, Alan;
- McCance, Dennis J.
Publication type:
Article
Characterization of the genomic features and expressed fusion genes in micropapillary carcinomas of the breast.
Published in:
Journal of Pathology, 2014, v. 232, n. 5, p. 553, doi. 10.1002/path.4325
By:
- Natrajan, Rachael;
- Wilkerson, Paul M;
- Marchiò, Caterina;
- Piscuoglio, Salvatore;
- Ng, Charlotte KY;
- Wai, Patty;
- Lambros, Maryou B;
- Samartzis, Eleftherios P;
- Dedes, Konstantin J;
- Frankum, Jessica;
- Bajrami, Ilirjana;
- Kopec, Alicja;
- Mackay, Alan;
- A'hern, Roger;
- Fenwick, Kerry;
- Kozarewa, Iwanka;
- Hakas, Jarle;
- Mitsopoulos, Costas;
- Hardisson, David;
- Lord, Christopher J
Publication type:
Article
The genomic landscape of oesophagogastric junctional adenocarcinoma.
Published in:
Journal of Pathology, 2013, v. 231, n. 3, p. 301, doi. 10.1002/path.4247
By:
- Chong, Irene Y;
- Cunningham, David;
- Barber, Louise J;
- Campbell, James;
- Chen, Lina;
- Kozarewa, Iwanka;
- Fenwick, Kerry;
- Assiotis, Ioannis;
- Guettler, Sebastian;
- Garcia‐Murillas, Isaac;
- Awan, Saima;
- Lambros, Maryou;
- Starling, Naureen;
- Wotherspoon, Andrew;
- Stamp, Gordon;
- Gonzalez‐de‐Castro, David;
- Benson, Martin;
- Chau, Ian;
- Hulkki, Sanna;
- Nohadani, Mahrokh
Publication type:
Article
Secondary mutations in BRCA2 associated with clinical resistance to a PARP inhibitor.
Published in:
Journal of Pathology, 2013, v. 229, n. 3, p. 422, doi. 10.1002/path.4140
By:
- Barber, Louise J;
- Sandhu, Shahneen;
- Chen, Lina;
- Campbell, James;
- Kozarewa, Iwanka;
- Fenwick, Kerry;
- Assiotis, Ioannis;
- Rodrigues, Daniel Nava;
- Reis-Filho, Jorge S;
- Moreno, Victor;
- Mateo, Joaquin;
- Molife, L Rhoda;
- De Bono, Johann;
- Kaye, Stan;
- Lord, Christopher J;
- Ashworth, Alan
Publication type:
Article
A whole-genome massively parallel sequencing analysis of BRCA1 mutant oestrogen receptor-negative and -positive breast cancers.
Published in:
Journal of Pathology, 2012, v. 227, n. 1, p. 29, doi. 10.1002/path.4003
By:
- Natrajan, Rachael;
- Mackay, Alan;
- Lambros, Maryou B;
- Weigelt, Britta;
- Wilkerson, Paul M;
- Manie, Elodie;
- Grigoriadis, Anita;
- A'Hern, Roger;
- van der Groep, Petra;
- Kozarewa, Iwanka;
- Popova, Tatiana;
- Mariani, Odette;
- Turajlic, Samra;
- Furney, Simon J;
- Marais, Richard;
- Rodruigues, Daniel-Nava;
- Flora, Adriana C;
- Wai, Patty;
- Pawar, Vidya;
- McDade, Simon
Publication type:
Article
Target-enrichment strategies for next-generation sequencing.
Published in:
2010
By:
- Mamanova, Lira;
- Coffey, Alison J;
- Scott, Carol E;
- Kozarewa, Iwanka;
- Turner, Emily H;
- Kumar, Akash;
- Howard, Eleanor;
- Shendure, Jay;
- Turner, Daniel J
Publication type:
Correction Notice
Target-enrichment strategies for next-generation sequencing.
Published in:
Nature Methods, 2010, v. 7, n. 2, p. 111, doi. 10.1038/nmeth.1419
By:
- Mamanova, Lira;
- Coffey, Alison J.;
- Scott, Carol E.;
- Kozarewa, Iwanka;
- Turner, Emily H.;
- Kumar, Akash;
- Howard, Eleanor;
- Shendure, Jay;
- Turner, Daniel J.
Publication type:
Article
Amplification-free Illumina sequencing-library preparation facilitates improved mapping and assembly of (G+C)-biased genomes.
Published in:
Nature Methods, 2009, v. 6, n. 4, p. 291, doi. 10.1038/nmeth.1311
By:
- Kozarewa, Iwanka;
- Zemin Ning;
- Quail, Michael A.;
- Sanders, Mandy J.;
- Berriman, Matthew;
- Turner, Daniel J.
Publication type:
Article
A large genome center's improvements to the Illumina sequencing system.
Published in:
Nature Methods, 2008, v. 5, n. 12, p. 1005, doi. 10.1038/nmeth.1270
By:
- Quail, Michael A.;
- Kozarewa, Iwanka;
- Smith, Frances;
- Scally, Aylwyn;
- Stephens, Philip J.;
- Durbin, Richard;
- Swerdlow, Harold;
- Turner, Daniel J.
Publication type:
Article
Efficient Genotyping of KRAS Mutant Non-Small Cell Lung Cancer Using a Multiplexed Droplet Digital PCR Approach.
Published in:
PLoS ONE, 2015, v. 10, n. 9, p. 1, doi. 10.1371/journal.pone.0139074
By:
- Pender, Alexandra;
- Garcia-Murillas, Isaac;
- Rana, Sareena;
- Cutts, Rosalind J.;
- Kelly, Gavin;
- Fenwick, Kerry;
- Kozarewa, Iwanka;
- Gonzalez de Castro, David;
- Bhosle, Jaishree;
- O’Brien, Mary;
- Turner, Nicholas C.;
- Popat, Sanjay;
- Downward, Julian
Publication type:
Article
A Genetic Screen Using the PiggyBac Transposon in Haploid Cells Identifies <i>Parp1</i> as a Mediator of Olaparib Toxicity.
Published in:
PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0061520
By:
- Pettitt, Stephen J.;
- Rehman, Farah L.;
- Bajrami, Ilirjana;
- Brough, Rachel;
- Wallberg, Fredrik;
- Kozarewa, Iwanka;
- Fenwick, Kerry;
- Assiotis, Ioannis;
- Chen, Lina;
- Campbell, James;
- Lord, Christopher J.;
- Ashworth, Alan
Publication type:
Article
A Modified Method for Whole Exome Resequencing from Minimal Amounts of Starting DNA.
Published in:
PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0032617
By:
- Kozarewa, Iwanka;
- Rosa-Rosa, Juan Manuel;
- Wardell, Christopher P.;
- Walker, Brian A.;
- Fenwick, Kerry;
- Assiotis, Ioannis;
- Mitsopoulos, Costas;
- Zvelebil, Marketa;
- Morgan, Gareth J.;
- Ashworth, Alan;
- Lord, Christopher J.
Publication type:
Article
Comprehensive Genomic Analysis of a BRCA2 Deficient Human Pancreatic Cancer.
Published in:
PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0021639
By:
- Barber, Louise J.;
- Rosa Rosa, Juan M.;
- Kozarewa, Iwanka;
- Fenwick, Kerry;
- Assiotis, Ioannis;
- Mitsopoulos, Costas;
- Sims, David;
- Hakas, Jarle;
- Zvelebil, Marketa;
- Lord, Christopher J.;
- Ashworth, Alan
Publication type:
Article
Whole Genome Sequencing Highlights Genetic Changes Associated with Laboratory Domestication of C. elegans.
Published in:
PLoS ONE, 2010, v. 5, n. 11, p. 1, doi. 10.1371/journal.pone.0013922
By:
- Weber, Katherine P.;
- De, Subhajyoti;
- Kozarewa, Iwanka;
- Turner, Daniel J.;
- Babu, M. Madan;
- de Bono, Mario
Publication type:
Article
High altitude adaptation in Daghestani populations from the Caucasus.
Published in:
Human Genetics, 2012, v. 131, n. 3, p. 423, doi. 10.1007/s00439-011-1084-8
By:
- Pagani, Luca;
- Ayub, Qasim;
- MacArthur, Daniel;
- Xue, Yali;
- Baillie, J.;
- Chen, Yuan;
- Kozarewa, Iwanka;
- Turner, Daniel;
- Tofanelli, Sergio;
- Bulayeva, Kazima;
- Kidd, Kenneth;
- Paoli, Giorgio;
- Tyler-Smith, Chris
Publication type:
Article
Homologous Recombination Repair Gene Mutation Characterization by Liquid Biopsy: A Phase II Trial of Olaparib and Abiraterone in Metastatic Castrate-Resistant Prostate Cancer.
Published in:
Cancers, 2021, v. 13, n. 22, p. 5830, doi. 10.3390/cancers13225830
By:
- Carr, T. Hedley;
- Adelman, Carrie;
- Barnicle, Alan;
- Kozarewa, Iwanka;
- Luke, Sally;
- Lai, Zhongwu;
- Hollis, Sally;
- Dougherty, Brian;
- Harrington, Elizabeth A.;
- Kang, Jinyu;
- Saad, Fred;
- Sala, Nuria;
- Thiery-Vuillemin, Antoine;
- Clarke, Noel W.;
- Hodgson, Darren;
- Barrett, J. Carl
Publication type:
Article
Alteration of PHYA expression change circadian rhythms and timing of bud set in Populus.
Published in:
Plant Molecular Biology, 2010, v. 73, n. 1-2, p. 143, doi. 10.1007/s11103-010-9619-2
By:
- Kozarewa, Iwanka;
- Ibáñez, Cristian;
- Johansson, Mikael;
- Ögren, Erling;
- Mozley, David;
- Nylander, Eva;
- Chono, Makiko;
- Moritz, Thomas;
- Eriksson, Maria E.
Publication type:
Article
Whole genome in vivo RNAi screening identifies the leukemia inhibitory factor receptor as a novel breast tumor suppressor.
Published in:
Breast Cancer Research & Treatment, 2010, v. 135, n. 1, p. 79, doi. 10.1007/s10549-012-2068-7
By:
- Iorns, Elizabeth;
- Ward, Toby;
- Dean, Sonja;
- Jegg, Anna;
- Thomas, Dafydd;
- Murugaesu, Nirupa;
- Sims, David;
- Mitsopoulos, Costas;
- Fenwick, Kerry;
- Kozarewa, Iwanka;
- Naceur-Lombarelli, Cristina;
- Zvelebil, Marketa;
- Isacke, Clare;
- Lord, Christopher;
- Ashworth, Alan;
- Hnatyszyn, H.;
- Pegram, Mark;
- Lippman, Marc
Publication type:
Article
ZEITLUPE Promotes ABA-Induced Stomatal Closure in Arabidopsis and Populus.
Published in:
Frontiers in Plant Science, 2022, v. 13, p. 1, doi. 10.3389/fpls.2022.829121
By:
- Jurca, Manuela;
- Sjölander, Johan;
- Ibáñez, Cristian;
- Matrosova, Anastasia;
- Johansson, Mikael;
- Kozarewa, Iwanka;
- Takata, Naoki;
- Bakó, Laszlo;
- Webb, Alex A. R.;
- Israelsson-Nordström, Maria;
- Eriksson, Maria E.
Publication type:
Article
Analysis of ESR1 mutation in circulating tumor DNA demonstrates evolution during therapy for metastatic breast cancer.
Published in:
Science Translational Medicine, 2015, v. 7, n. 313, p. 1, doi. 10.1126/scitranslmed.aac7551
By:
- Schiavon, Gaia;
- Hrebien, Sarah;
- Garcia-Murillas, Isaac;
- Cutts, Rosalind J.;
- Pearson, Alex;
- Tarazona, Noelia;
- Fenwick, Kerry;
- Iwanka Kozarewa;
- Lopez-Knowles, Elena;
- Ribas, Ricardo;
- Nerurkar, Ashutosh;
- Osin, Peter;
- Chandarlapaty, Sarat;
- Martin, Lesley-Ann;
- Dowsett, Mitch;
- Smith, Ian E.;
- Turner, Nicholas C.
Publication type:
Article
Mutation tracking in circulating tumor DNA predicts relapse in early breast cancer.
Published in:
Science Translational Medicine, 2015, v. 7, n. 302, p. 1, doi. 10.1126/scitranslmed.aab0021
By:
- Garcia-Murillas, Isaac;
- Schiavon, Gaia;
- Weigelt, Britta;
- Ng, Charlotte;
- Hrebien, Sarah;
- Cutts, Rosalind J.;
- Cheang, Maggie;
- Osin, Peter;
- Nerurkar, Ashutosh;
- Kozarewa, Iwanka;
- Garrido, Javier Armisen;
- Dowsett, Mitch;
- Reis-Filho, Jorge S.;
- Smith, Ian E.;
- Turner, Nicholas C.
Publication type:
Article
High-throughput RNA interference screening using pooled shRNA libraries and next generation sequencing.
Published in:
Genome Biology, 2011, v. 12, n. 10, p. 1, doi. 10.1186/gb-2011-12-10-r104
By:
- Sims, David;
- Mendes-Pereira, Ana M.;
- Frankum, Jessica;
- Burgess, Darren;
- Cerone, Maria-Antonietta;
- Lombardelli, Cristina;
- Mitsopoulos, Lombardelli;
- Hakas, Jarle;
- Murugaesu, Nirupa;
- Isacke, Clare M.;
- Fenwick, Kerry;
- Assiotis, Ioannis;
- Kozarewa, Iwanka;
- Zvelebil, Marketa;
- Ashworth, Alan;
- Lord, Christopher J.
Publication type:
Article
Circadian Clock Components Regulate Entry and Affect Exit of Seasonal Dormancy as Well as Winter Hardiness in Populus Trees.
Published in:
Plant Physiology, 2010, v. 153, n. 4, p. 1823
By:
- Ibáñe, Cristian;
- Kozarewa, Iwanka;
- Johansson, Mikael;
- Ögren, Erling;
- Rohde, Antje;
- Eriksson, Maria E.
Publication type:
Article
Genomic characterisation of acral melanoma cell lines.
Published in:
Pigment Cell & Melanoma Research, 2012, v. 25, n. 4, p. 488, doi. 10.1111/j.1755-148X.2012.01016.x
By:
- Furney, Simon J.;
- Turajlic, Samra;
- Fenwick, Kerry;
- Lambros, Maryou B.;
- MacKay, Alan;
- Ricken, Gerda;
- Mitsopoulos, Costas;
- Kozarewa, Iwanka;
- Hakas, Jarle;
- Zvelebil, Marketa;
- Lord, Christopher J.;
- Ashworth, Alan;
- Reis-Filho, Jorge S.;
- Herlyn, Meenhard;
- Murata, Hiroshi;
- Marais, Richard
Publication type:
Article

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