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Age-specific survival in acute myeloid leukemia in the Nordic countries through a half century.
Published in:
Blood Cancer Journal, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41408-024-01033-7
By:
- Hemminki, Kari;
- Zitricky, Frantisek;
- Försti, Asta;
- Kontro, Mika;
- Gjertsen, Bjorn T.;
- Severinsen, Marianne Tang;
- Juliusson, Gunnar
Publication type:
Article
FLT3-ITD allelic ratio and HLF expression predict FLT3 inhibitor efficacy in adult AML.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-03010-7
By:
- Kivioja, Jarno;
- Malani, Disha;
- Kumar, Ashwini;
- Kontro, Mika;
- Parsons, Alun;
- Kallioniemi, Olli;
- Heckman, Caroline A.
Publication type:
Article
8‐chloro‐adenosine activity in FLT3‐ITD acute myeloid leukemia.
Published in:
Journal of Cellular Physiology, 2019, v. 234, n. 9, p. 16295, doi. 10.1002/jcp.28294
By:
- Buettner, Ralf;
- Nguyen, Le Xuan Truong;
- Kumar, Bijender;
- Morales, Corey;
- Liu, Chao;
- Chen, Lisa S.;
- Pemovska, Tea;
- Synold, Timothy W.;
- Palmer, Joycelynne;
- Thompson, Ryan;
- Li, Ling;
- Hoang, Dinh Hoa;
- Zhang, Bin;
- Ghoda, Lucy;
- Kowolik, Claudia;
- Kontro, Mika;
- Leitch, Calum;
- Wennerberg, Krister;
- Yu, Xiaochun;
- Chen, Ching‐Cheng
Publication type:
Article
Phase Ib study of sabatolimab (MBG453), a novel immunotherapy targeting TIM‐3 antibody, in combination with decitabine or azacitidine in high‐ or very high‐risk myelodysplastic syndromes.
Published in:
American Journal of Hematology, 2024, v. 99, n. 2, p. E32, doi. 10.1002/ajh.27161
By:
- Brunner, Andrew M.;
- Esteve, Jordi;
- Porkka, Kimmo;
- Knapper, Steve;
- Traer, Elie;
- Scholl, Sebastian;
- Garcia‐Manero, Guillermo;
- Vey, Norbert;
- Wermke, Martin;
- Janssen, Jeroen J. W. M.;
- Narayan, Rupa;
- Fleming, Shaun;
- Loo, Sun;
- Tovar, Natalia;
- Kontro, Mika;
- Ottmann, Oliver G.;
- Naidu, Purushotham;
- Sun, Haiying;
- Han, May;
- White, Roisin
Publication type:
Article
Allelic Imbalance of Recurrently Mutated Genes in Acute Myeloid Leukaemia.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-48167-4
By:
- Batcha, Aarif M. N.;
- Bamopoulos, Stefanos A.;
- Kerbs, Paul;
- Kumar, Ashwini;
- Jurinovic, Vindi;
- Rothenberg-Thurley, Maja;
- Ksienzyk, Bianka;
- Philippou-Massier, Julia;
- Krebs, Stefan;
- Blum, Helmut;
- Schneider, Stephanie;
- Konstandin, Nikola;
- Bohlander, Stefan K.;
- Heckman, Caroline;
- Kontro, Mika;
- Hiddemann, Wolfgang;
- Spiekermann, Karsten;
- Braess, Jan;
- Metzeler, Klaus H.;
- Greif, Philipp A.
Publication type:
Article
Vascular adhesion protein-1 defines a unique subpopulation of human hematopoietic stem cells and regulates their proliferation.
Published in:
Cellular & Molecular Life Sciences, 2021, v. 78, n. 23, p. 7851, doi. 10.1007/s00018-021-03977-6
By:
- Iftakhar-e-Khuda, Imtiaz;
- Pessia, Alberto;
- Zheng, Shuyu;
- Kankainen, Matti;
- Kontro, Mika;
- Karikoski, Marika;
- Laurila, Juha;
- Gerke, Heidi;
- Tadayon, Sina;
- Hollmén, Maija;
- Tang, Jing;
- Imhof, Beat A.;
- Salmi, Marko;
- Jalkanen, Sirpa
Publication type:
Article
MDS-404: Population Pharmacokinetics Modeling and Evaluation of Clinical Efficacy and Safety of Sabatolimab: Dose Selection and Dose-Response Analysis.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2021, v. 21, p. S349, doi. 10.1016/S2152-2650(21)01810-3
By:
- Garcia-Manero, Guillermo;
- Wei, Andrew H.;
- Porkka, Kimmo;
- Knapper, Steve;
- Vey, Norbert;
- Scholl, Sebastian;
- Wermke, Martin;
- Janssen, Jeroen;
- Traer, Elie;
- Sun Loo;
- Narayan, Rupa;
- Tovar, Natalia;
- Kontro, Mika;
- Ottmann, Oliver;
- Siyan Xu;
- Lewandowski, Andrew;
- Stein, Andrew;
- Naidu, Purushotham;
- Na Zhang;
- Mohammed, Anisa
Publication type:
Article
MDS-420: Sabatolimab Plus Hypomethylating Agents (HMAs) in Patients with High-/Very High-risk Myelodysplastic Syndrome (HR/vHR-MDS) and Newly Diagnosed Acute Myeloid Leukemia (ND-AML): Subgroup Analysis of a Phase 1 Study.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2021, v. 21, p. S350, doi. 10.1016/S2152-2650(21)01811-5
By:
- Garcia-Manero, Guillermo;
- Wei, Andrew H.;
- Porkka, Kimmo;
- Knapper, Steve;
- Traer, Elie;
- Scholl, Sebastian;
- Vey, Norbert;
- Wermke, Martin;
- Janssen, Jeroen;
- Narayan, Rupa;
- Sun Loo;
- Tovar, Natalia;
- Kontro, Mika;
- Ottmann, Oliver;
- Naidu, Purushotham;
- Orlando, Elena;
- Patei, Nidhi;
- Makofske, Jessica;
- Fei Ma;
- Na Zhang
Publication type:
Article
Poster: MDS-404: Population Pharmacokinetics Modeling and Evaluation of Clinical Efficacy and Safety of Sabatolimab: Dose Selection and Dose-Response Analysis.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2021, v. 21, p. S230, doi. 10.1016/S2152-2650(21)01448-8
By:
- Garcia-Manero, Guillermo;
- Wei, Andrew H.;
- Porkka, Kimmo;
- Knapper, Steve;
- Vey, Norbert;
- Scholl, Sebastian;
- Wermke, Martin;
- Janssen, Jeroen;
- Traer, Elie;
- Sun Loo;
- Narayan, Rupa;
- Tovar, Natalia;
- Kontro, Mika;
- Ottmann, Oliver;
- Siyan Xu;
- Lewandowski, Andrew;
- Stein, Andrew;
- Naidu, Purushotham;
- Na Zhang;
- Mohammed, Anisa
Publication type:
Article
Poster: MDS-420: Sabatolimab Plus Hypomethylating Agents (HMAs) in Patients with High-/Very High-risk Myelodysplastic Syndrome (HR/vHR-MDS) and Newly Diagnosed Acute Myeloid Leukemia (ND-AML): Subgroup Analysis of a Phase 1 Study.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2021, v. 21, p. S230, doi. 10.1016/S2152-2650(21)01447-6
By:
- Garcia-Manero, Guillermo;
- Wei, Andrew H.;
- Porkka, Kimmo;
- Knapper, Steve;
- Traer, Elie;
- Scholl, Sebastian;
- Vey, Norbert;
- Wermke, Martin;
- Janssen, Jeroen;
- Narayan, Rupa;
- Sun Loo;
- Tovar, Natalia;
- Kontro, Mika;
- Ottmann, Oliver;
- Naidu, Purushotham;
- Orlando, Elena;
- Patel, Nidhi;
- Makofske, Jessica;
- Fei Ma;
- Na Zhang
Publication type:
Article
Somatic MED12 Mutations in Prostate Cancer and Uterine Leiomyomas Promote Tumorigenesis Through Distinct Mechanisms.
Published in:
Prostate, 2016, v. 76, n. 1, p. 22, doi. 10.1002/pros.23092
By:
- Kämpjärvi, Kati;
- Kim, Nam Hee;
- Keskitalo, Salla;
- Clark, Alison D.;
- von Nandelstadh, Pernilla;
- Turunen, Mikko;
- Heikkinen, Tuomas;
- Park, Min Ju;
- Mäkinen, Netta;
- Kivinummi, Kati;
- Lintula, Susanna;
- Hotakainen, Kristina;
- Nevanlinna, Heli;
- Hokland, Peter;
- Böhling, Tom;
- Bützow, Ralf;
- Böhm, Jan;
- Mecklin, Jukka‐Pekka;
- Järvinen, Heikki;
- Kontro, Mika
Publication type:
Article
Axitinib effectively inhibits BCR-ABL1(T315I) with a distinct binding conformation.
Published in:
Nature, 2015, v. 519, n. 7541, p. 102, doi. 10.1038/nature14119
By:
- Pemovska, Tea;
- Johnson, Eric;
- Kontro, Mika;
- Repasky, Gretchen A.;
- Chen, Jeffrey;
- Wells, Peter;
- Cronin, Ciarán N.;
- McTigue, Michele;
- Kallioniemi, Olli;
- Porkka, Kimmo;
- Murray, Brion W.;
- Wennerberg, Krister
Publication type:
Article
Quantitative scoring of differential drug sensitivity for individually optimized anticancer therapies.
Published in:
Scientific Reports, 2014, p. 1, doi. 10.1038/srep05193
By:
- Yadav, Bhagwan;
- Pemovska, Tea;
- Szwajda, Agnieszka;
- Kulesskiy, Evgeny;
- Kontro, Mika;
- Karjalainen, Riikka;
- Mamun Majumder, Muntasir;
- Malani, Disha;
- Murumägi, Astrid;
- Knowles, Jonathan;
- Porkka, Kimmo;
- Heckman, Caroline;
- Kallioniemi, Olli;
- Wennerberg, Krister;
- Aittokallio, Tero
Publication type:
Article
Somatic MED12 Nonsense Mutation Escapes mRNA Decay and Reveals a Motif Required for Nuclear Entry.
Published in:
Human Mutation, 2017, v. 38, n. 3, p. 269, doi. 10.1002/humu.23157
By:
- Heikkinen, Tuomas;
- Kämpjärvi, Kati;
- Keskitalo, Salla;
- von Nandelstadh, Pernilla;
- Liu, Xiaonan;
- Rantanen, Ville;
- Pitkänen, Esa;
- Kinnunen, Matias;
- Kuusanmäki, Heikki;
- Kontro, Mika;
- Turunen, Mikko;
- Mäkinen, Netta;
- Taipale, Jussi;
- Heckman, Caroline;
- Lehti, Kaisa;
- Mustjoki, Satu;
- Varjosalo, Markku;
- Vahteristo, Pia
Publication type:
Article
Single-cell transcriptomes identify patient-tailored therapies for selective co-inhibition of cancer clones.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52980-5
By:
- Ianevski, Aleksandr;
- Nader, Kristen;
- Driva, Kyriaki;
- Senkowski, Wojciech;
- Bulanova, Daria;
- Moyano-Galceran, Lidia;
- Ruokoranta, Tanja;
- Kuusanmäki, Heikki;
- Ikonen, Nemo;
- Sergeev, Philipp;
- Vähä-Koskela, Markus;
- Giri, Anil K.;
- Vähärautio, Anna;
- Kontro, Mika;
- Porkka, Kimmo;
- Pitkänen, Esa;
- Heckman, Caroline A.;
- Wennerberg, Krister;
- Aittokallio, Tero
Publication type:
Article

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