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Retargeting of adenoviral infection to melanoma: Combining genetic ablation of native tropism with a recombinant bispecific single-chain diabody (scDb) adapter that binds to fiber knob and HMWMAA.
- Published in:
- International Journal of Cancer, 2004, v. 108, n. 1, p. 136, doi. 10.1002/ijc.11563
- By:
- Publication type:
- Article
Focal adhesion kinase plays a dual role in TRAIL resistance and metastatic outgrowth of malignant melanoma.
- Published in:
- Cell Death & Disease, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41419-022-04502-8
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- Publication type:
- Article
TNF-Receptor-1 inhibition reduces liver steatosis, hepatocellular injury and fibrosis in NAFLD mice.
- Published in:
- Cell Death & Disease, 2020, v. 11, n. 3, p. 1, doi. 10.1038/s41419-020-2411-6
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- Publication type:
- Article
Sensitization of glioblastoma cells to TRAIL-induced apoptosis by IAP- and Bcl-2 antagonism.
- Published in:
- Cell Death & Disease, 2018, v. 9, n. 11, p. 1, doi. 10.1038/s41419-018-1160-2
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- Publication type:
- Article
A fusogenic dengue virus-derived peptide enhances antitumor efficacy of an antibody–ribonuclease fusion protein targeting the EGF receptor.
- Published in:
- PEDS: Protein Engineering, Design & Selection, 2014, v. 27, n. 10, p. 331, doi. 10.1093/protein/gzu040
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- Publication type:
- Article
An anti-TNFR1 scFv-HSA fusion protein as selective antagonist of TNF action.
- Published in:
- PEDS: Protein Engineering, Design & Selection, 2013, v. 26, n. 10, p. 581, doi. 10.1093/protein/gzt044
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- Publication type:
- Article
The IgM CH2 domain as covalently linked homodimerization module for the generation of fusion proteins with dual specificity.
- Published in:
- PEDS: Protein Engineering, Design & Selection, 2012, v. 25, n. 10, p. 603, doi. 10.1093/protein/gzs059
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- Publication type:
- Article
Half-life extension of a single-chain diabody by fusion to domain B of staphylococcal protein A.
- Published in:
- PEDS: Protein Engineering, Design & Selection, 2012, v. 25, n. 2, p. 81, doi. 10.1093/protein/gzr061
- By:
- Publication type:
- Article
The effects of affinity and valency of an albumin-binding domain (ABD) on the half-life of a single-chain diabody-ABD fusion protein.
- Published in:
- PEDS: Protein Engineering, Design & Selection, 2010, v. 23, n. 11, p. 827, doi. 10.1093/protein/gzq058
- By:
- Publication type:
- Article
A novel tri-functional antibody fusion protein with improved pharmacokinetic properties generated by fusing a bispecific single-chain diabody with an albumin-binding domain from streptococcal protein G.
- Published in:
- PEDS: Protein Engineering, Design & Selection, 2007, v. 20, n. 11, p. 569, doi. 10.1093/protein/gzm061
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- Publication type:
- Article
Novel RGD lipopeptides for the targeting of liposomes to integrin-expressing endothelial and melanoma cells.
- Published in:
- PEDS: Protein Engineering, Design & Selection, 2004, v. 17, n. 5, p. 433, doi. 10.1093/protein/gzh055
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- Publication type:
- Article
A fast and effective determination of the biodistribution and subcellular localization of fluorescent immunoliposomes in freshly excised animal organs.
- Published in:
- BMC Biotechnology, 2017, v. 18, p. 1, doi. 10.1186/s12896-017-0327-8
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- Publication type:
- Article
GlycoTAIL and FlexiTAIL as Half-Life Extension Modules for Recombinant Antibody Fragments.
- Published in:
- Molecules, 2022, v. 27, n. 10, p. 3272, doi. 10.3390/molecules27103272
- By:
- Publication type:
- Article
Low-Level Endothelial TRAIL-Receptor Expression Obstructs the CNS-Delivery of Angiopep-2 Functionalised TRAIL-Receptor Agonists for the Treatment of Glioblastoma.
- Published in:
- Molecules, 2021, v. 26, n. 24, p. 7582, doi. 10.3390/molecules26247582
- By:
- Publication type:
- Article
Inhibition of cell proliferation and induction of apoptosis by novel tetravalent peptides inhibiting DNA binding of E2F.
- Published in:
- Oncogene, 2003, v. 22, n. 32, p. 4943, doi. 10.1038/sj.onc.1206495
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- Publication type:
- Article
Selective Activation of Tumor Necrosis Factor Receptor II Induces Antiinflammatory Responses and Alleviates Experimental Arthritis.
- Published in:
- Arthritis & Rheumatology, 2018, v. 70, n. 5, p. 722, doi. 10.1002/art.40413
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- Publication type:
- Article
Superior Treg-Expanding Properties of a Novel Dual-Acting Cytokine Fusion Protein.
- Published in:
- Frontiers in Pharmacology, 2019, v. 10, p. 1, doi. 10.3389/fphar.2019.01490
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- Publication type:
- Article
Bispecific Antibodies for Cancer Immunotherapy.
- Published in:
- BioDrugs, 2010, v. 24, n. 2, p. 89, doi. 10.2165/11530960-000000000-00000
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- Publication type:
- Article
Strategies to Extend Plasma Half-Lives of Recombinant Antibodies.
- Published in:
- BioDrugs, 2009, v. 23, n. 2, p. 93, doi. 10.2165/00063030-200923020-00003
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- Publication type:
- Article
Isolation from phage display libraries of lysine‐deficient human epidermal growth factor variants for directional conjugation as targeting ligands.
- Published in:
- Protein Engineering, 2003, v. 16, n. 12, p. 1107, doi. 10.1093/protein/gzg145
- By:
- Publication type:
- Article
Optimized linker sequences for the expression of monomeric and dimeric bispecific single-chain diabodies.
- Published in:
- Protein Engineering, 2001, v. 14, n. 10, p. 815, doi. 10.1093/protein/14.10.815
- By:
- Publication type:
- Article
Continuous infusion of an agonist of the tumor necrosis factor receptor 2 in the spinal cord improves recovery after traumatic contusive injury.
- Published in:
- CNS Neuroscience & Therapeutics, 2019, v. 25, n. 8, p. 884, doi. 10.1111/cns.13125
- By:
- Publication type:
- Article
Systemic network analysis identifies XIAP and IκBα as potential drug targets in TRAIL resistant BRAF mutated melanoma.
- Published in:
- NPJ Systems Biology & Applications, 2018, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41540-018-0075-y
- By:
- Publication type:
- Article
Antagonistic TNF Receptor One-Specific Antibody (ATROSAB): Receptor Binding and In Vitro Bioactivity.
- Published in:
- PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0072156
- By:
- Publication type:
- Article
Phenocopy -- A Strategy to Qualify Chemical Compounds during Hit-to-Lead and/or Lead Optimization.
- Published in:
- PLoS ONE, 2010, v. 5, n. 12, p. 1, doi. 10.1371/journal.pone.0014272
- By:
- Publication type:
- Article
Specific gene transfer to neurons, endothelial cells and hematopoietic progenitors with lentiviral vectors.
- Published in:
- Nature Methods, 2010, v. 7, n. 11, p. 929, doi. 10.1038/nmeth.1514
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- Publication type:
- Article
A scDb-based trivalent bispecific antibody for T-cell-mediated killing of HER3-expressing cancer cells.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-93351-0
- By:
- Publication type:
- Article
Pharmacokinetic Engineering of OX40-Blocking Anticalin Proteins Using Monomeric Plasma Half-Life Extension Domains.
- Published in:
- Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.759337
- By:
- Publication type:
- Article
Antitumor Activity of a Mesenchymal Stem Cell Line Stably Secreting a Tumor-Targeted TNF-Related Apoptosis-Inducing Ligand Fusion Protein.
- Published in:
- Frontiers in Immunology, 2017, v. 8, p. 1, doi. 10.3389/fimmu.2017.00536
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- Publication type:
- Article
Sequential treatment with a TNFR2 agonist and a TNFR1 antagonist improves outcomes in a humanized mouse model for MS.
- Published in:
- Journal of Neuroinflammation, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12974-023-02785-y
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- Publication type:
- Article
Co-modulation of TNFR1 and TNFR2 in an animal model of multiple sclerosis.
- Published in:
- Journal of Neuroinflammation, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12974-023-02784-z
- By:
- Publication type:
- Article
Transcytosis of payloads that are non-covalently complexed to bispecific antibodies across the hCMEC/D3 blood-brain barrier model.
- Published in:
- Biological Chemistry, 2018, v. 399, n. 7, p. 711, doi. 10.1515/hsz-2017-0311
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- Publication type:
- Article
Characterization of the Epitope Recognized by a Monoclonal Antibody Directed against the Largest Subunit of Drosophila RNA Polymerase II.
- Published in:
- Biological Chemistry, 1995, v. 376, n. 8, p. 473
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- Publication type:
- Article
Influence of antigen density and immunosuppressive factors on tumor-targeted costimulation with antibody-fusion proteins and bispecific antibody-mediated T cell response.
- Published in:
- Cancer Immunology, Immunotherapy, 2020, v. 69, n. 11, p. 2291, doi. 10.1007/s00262-020-02624-6
- By:
- Publication type:
- Article
Back-to-Germline (B2G) Procedure for Antibody Devolution.
- Published in:
- Antibodies (2073-4468), 2019, v. 8, n. 3, p. 45, doi. 10.3390/antib8030045
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- Publication type:
- Article
Targeting sTNF/TNFR1 Signaling as a New Therapeutic Strategy.
- Published in:
- Antibodies (2073-4468), 2015, v. 4, n. 1, p. 48, doi. 10.3390/antib4010048
- By:
- Publication type:
- Article
Dual Targeting of Tumor Cells with Bispecific Single-Chain Fv-Immunoliposomes.
- Published in:
- Antibodies (2073-4468), 2012, v. 1, n. 2, p. 199, doi. 10.3390/antib1020199
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- Publication type:
- Article
Antibody phage display technologies with special reference to angiogenesis.
- Published in:
- FASEB Journal, 2005, v. 19, n. 3, p. 331, doi. 10.1096/fj.04-2863rev
- By:
- Publication type:
- Article
Recombinant bispecific antibodies for cancer therapy.
- Published in:
- Acta Pharmacologica Sinica, 2005, v. 26, n. 1, p. 1, doi. 10.1111/j.1745-7254.2005.00008.x
- By:
- Publication type:
- Article
The TNFR1 Antagonist Atrosimab Is Therapeutic in Mouse Models of Acute and Chronic Inflammation.
- Published in:
- Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.705485
- By:
- Publication type:
- Article
Genetic delivery of an immuno RNase by an oncolytic adenovirus enhances anticancer activity.
- Published in:
- International Journal of Cancer, 2015, v. 136, n. 9, p. 2228, doi. 10.1002/ijc.29258
- By:
- Publication type:
- Article
Rapid Target Binding and Cargo Release of Activatable Liposomes Bearing HER2 and FAP Single-Chain Antibody Fragments Reveal Potentials for Image-Guided Delivery to Tumors.
- Published in:
- Pharmaceutics, 2020, v. 12, n. 10, p. 972, doi. 10.3390/pharmaceutics12100972
- By:
- Publication type:
- Article
Targeting the Tumor Microenvironment with Fluorescence-Activatable Bispecific Endoglin/Fibroblast Activation Protein Targeting Liposomes.
- Published in:
- Pharmaceutics, 2020, v. 12, n. 4, p. 370, doi. 10.3390/pharmaceutics12040370
- By:
- Publication type:
- Article
Evaluation of the Neutralizing Antibody STE90-C11 against SARS-CoV-2 Delta Infection and Its Recognition of Other Variants of Concerns.
- Published in:
- Viruses (1999-4915), 2023, v. 15, n. 11, p. 2153, doi. 10.3390/v15112153
- By:
- Publication type:
- Article
A Fab-Selective Immunoglobulin-Binding Domain from Streptococcal Protein G with Improved Half-Life Extension Properties.
- Published in:
- PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0139838
- By:
- Publication type:
- Article
Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKKβ promote microglial responses and tissue injury in demyelination while TNFR2 protects against excitotoxicity in mice.
- Published in:
- 2021
- By:
- Publication type:
- journal article