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Therapeutic mitigation of measles-like immune amnesia and exacerbated disease after prior respiratory virus infections in ferrets.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45418-5
By:
- Cox, Robert M.;
- Wolf, Josef D.;
- Lieberman, Nicole A.;
- Lieber, Carolin M.;
- Kang, Hae-Ji;
- Sticher, Zachary M.;
- Yoon, Jeong-Joong;
- Andrews, Meghan K.;
- Govindarajan, Mugunthan;
- Krueger, Rebecca E.;
- Sobolik, Elizabeth B.;
- Natchus, Michael G.;
- Gewirtz, Andrew T.;
- deSwart, Rik L.;
- Kolykhalov, Alexander A.;
- Hekmatyar, Khan;
- Sakamoto, Kaori;
- Greninger, Alexander L.;
- Plemper, Richard K.
Publication type:
Article
Comparing molnupiravir and nirmatrelvir/ritonavir efficacy and the effects on SARS-CoV-2 transmission in animal models.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40556-8
By:
- Cox, Robert M.;
- Lieber, Carolin M.;
- Wolf, Josef D.;
- Karimi, Amirhossein;
- Lieberman, Nicole A. P.;
- Sticher, Zachary M.;
- Roychoudhury, Pavitra;
- Andrews, Meghan K.;
- Krueger, Rebecca E.;
- Natchus, Michael G.;
- Painter, George R.;
- Kolykhalov, Alexander A.;
- Greninger, Alexander L.;
- Plemper, Richard K.
Publication type:
Article
Safe, Long-term Hepatic Expression of Anti-HCV shRNA in a Nonhuman Primate Model.
Published in:
Molecular Therapy, 2012, v. 20, n. 9, p. 1737, doi. 10.1038/mt.2012.119
By:
- Suhy, David A;
- Kao, Shih-Chu;
- Mao, Tin;
- Whiteley, Laurence;
- Denise, Hubert;
- Souberbielle, Bernard;
- Burdick, Andrew D;
- Hayes, Kyle;
- Wright, J Fraser;
- Lavender, Helen;
- Roelvink, Peter;
- Kolykhalov, Alexander;
- Brady, Kevin;
- Moschos, Sterghios A;
- Hauck, Bernd;
- Zelenaia, Olga;
- Zhou, Shangzhen;
- Scribner, Curt;
- High, Katherine A;
- Renison, Sara H
Publication type:
Article
Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia.
Published in:
Science Translational Medicine, 2019, v. 11, n. 515, p. 1, doi. 10.1126/scitranslmed.aax5866
By:
- Toots, Mart;
- Yoon, Jeong-Joong;
- Cox, Robert M.;
- Hart, Michael;
- Sticher, Zachary M.;
- Makhsous, Negar;
- Plesker, Roland;
- Barrena, Alec H.;
- Reddy, Prabhakar G.;
- Mitchell, Deborah G.;
- Shean, Ryan C.;
- Bluemling, Gregory R.;
- Kolykhalov, Alexander A.;
- Greninger, Alexander L.;
- Natchus, Michael G.;
- Painter, George R.;
- Plemper, Richard K.
Publication type:
Article
1034. Expression of Short Hairpin RNAs by Liver and Non Liver Specific RNA Pol II Expression Cassettes: What Governs Activity?
Published in:
Molecular Therapy, 2006, v. 13, p. S397, doi. 10.1016/j.ymthe.2006.08.1129
By:
- Suhy, David A.;
- Kolykhalov, Alexander A.;
- Couto, Linda B.;
- Garcia, Luz-Maria;
- Schroeder, Annette R.;
- Parker, Amy E.;
- Haniff, Gabriel;
- Kay, Mark A.;
- Roelvink, Peter W.
Publication type:
Article
1099. RNAi-Based Therapy for the Treatment of HCV.
Published in:
Molecular Therapy, 2006, v. 13, p. S422, doi. 10.1016/j.ymthe.2006.08.1203
By:
- Couto, Linda B.;
- Parker, Amy E.;
- Haniff, Gabriel;
- Suhy, David A.;
- Kolykhalov, Alexander A.;
- Roelvink, Peter W.;
- Maria Garcia, Luz;
- Schroeder, Rosanna;
- Kay, Mark A.;
- Cunningham, Sara M.
Publication type:
Article
1000. In Vitro and In Vivo Evaluation of Optimized Short-Hairpin RNAs for the Treatment of the Hepatitis C Virus Using Expression Cassettes Producing One, Two or Three Anti HCV shRNAs
Published in:
2005
By:
- Suhy, David A.;
- Couto, Linda B.;
- Kolykhalov, Alexander A.;
- Parker, Amy E.;
- Schroeder, A. Rosanna;
- Garcia, Luz Maria;
- Haniff, Gabriel;
- Cunningham, Sara M.;
- Kay, Mark A.;
- Roelvink, Peter W.
Publication type:
Abstract
997. Loop Composition as Well as Orientation of the Guide Strand in shRNA May Dramatically Modulate Activity of the shRNA: Effect on the Development of RNAi-Based Inhibitors
Published in:
2005
By:
- Kolykhalov, Alexander A.;
- Graham, Michael W.;
- Suhy, David A.;
- Roelvink, Peter W.;
- Schroeder, Annette R.;
- Parker, Amy E.;
- Garcia, Luz M.;
- Kay, Mark A.;
- Cunningham, Sara M.;
- Couto, Linda B.
Publication type:
Abstract
443. Tissue Specific Expression of Short Hairpin RNAs for the Treatment of HCV Using Liver Specific RNA Pol II Expression Cassettes
Published in:
2005
By:
- Suhy, David A.;
- Kolykhalov, Alexander A.;
- Couto, Linda B.;
- Garcia, Luz Maria;
- Schroeder, A. Rosanna;
- Parker, Amy E.;
- Haniff, Gabriel;
- Cunningham, Sara M.;
- Kay, Mark A.;
- Roelvink, Peter W.
Publication type:
Abstract
437. Alternative Strategies To Deliver Multiple shRNAs in Order to Simultaneously Inhibit Multiple Targets
Published in:
2005
By:
- Roelvink, Peter W.;
- Graham, Michael W.;
- Suhy, David A.;
- Couto, Linda B.;
- Cunningham, Sara M.;
- Kay, Mark A.;
- Rossi, John J.;
- Kolykhalov, Alexander A.
Publication type:
Abstract
4'-Fluorouridine mitigates lethal infection with pandemic human and highly pathogenic avian influenza viruses.
Published in:
PLoS Pathogens, 2023, v. 18, n. 4, p. 1, doi. 10.1371/journal.ppat.1011342
By:
- Lieber, Carolin M.;
- Aggarwal, Megha;
- Yoon, Jeong-Joong;
- Cox, Robert M.;
- Kang, Hae-Ji;
- Sourimant, Julien;
- Toots, Mart;
- Johnson, Scott K.;
- Jones, Cheryl A.;
- Sticher, Zachary M.;
- Kolykhalov, Alexander A.;
- Saindane, Manohar T.;
- Tompkins, Stephen M.;
- Planz, Oliver;
- Painter, George R.;
- Natchus, Michael G.;
- Sakamoto, Kaori;
- Plemper, Richard K.
Publication type:
Article

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