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Guselkumab Modulates Differentially Expressed Genes in Blood of Patients With Psoriatic Arthritis: Results from Two Phase 3, Randomized, Placebo‐Controlled Trials.
Published in:
ACR Open Rheumatology, 2023, v. 5, n. 9, p. 490, doi. 10.1002/acr2.11589
By:
- Siebert, Stefan;
- Sweet, Kristen M.;
- Ritchlin, Christopher T.;
- Hsia, Elizabeth C.;
- Kollmeier, Alexa P.;
- Xu, Xie L.;
- Seridi, Loqmane;
- Song, Qingxuan;
- Gao, Sheng;
- Chen, Warner;
- Miron, Michelle
Publication type:
Article
Guselkumab, a Selective Interleukin‐23 p19 Subunit Inhibitor, Resolves Dactylitis in Patients With Active Psoriatic Arthritis: Pooled Results Through Week 52 From Two Phase 3 Studies.
Published in:
ACR Open Rheumatology, 2023, v. 5, n. 4, p. 227, doi. 10.1002/acr2.11537
By:
- McGonagle, Dennis;
- McInnes, Iain B.;
- Deodhar, Atul;
- Schett, Georg;
- Shawi, May;
- Chakravarty, Soumya D.;
- Kollmeier, Alexa P.;
- Xu, Xie L.;
- Sheng, Shihong;
- Xu, Stephen;
- Ritchlin, Christopher T.;
- Rahman, Proton;
- Mease, Phillip J.
Publication type:
Article
Multidomain Efficacy and Safety of Guselkumab Through 1 Year in Patients With Active Psoriatic Arthritis With and Without Prior Tumor Necrosis Factor Inhibitor Experience: Analysis of the Phase 3, Randomized, Placebo‐Controlled DISCOVER‐1 Study
Published in:
ACR Open Rheumatology, 2023, v. 5, n. 3, p. 149, doi. 10.1002/acr2.11523
By:
- Ritchlin, Christopher T.;
- Deodhar, Atul;
- Boehncke, Wolf‐Henning;
- Soriano, Enrique R.;
- Kollmeier, Alexa P.;
- Xu, Xie L.;
- Zazzetti, Federico;
- Shawi, May;
- Jiang, Yusang;
- Sheng, Shihong;
- Helliwell, Philip S.
Publication type:
Article
Meaningful Improvement in General Health Outcomes with Guselkumab Treatment for Psoriatic Arthritis: Patient-Reported Outcomes Measurement Information System-29 Results from a Phase 3 Study.
Published in:
Patient, 2022, v. 15, n. 6, p. 657, doi. 10.1007/s40271-022-00588-6
By:
- Orbai, Ana-Maria;
- Coates, Laura C.;
- Deodhar, Atul;
- Helliwell, Philip S.;
- Ritchlin, Christopher T.;
- Leibowitz, Evan;
- Kollmeier, Alexa P.;
- Hsia, Elizabeth C.;
- Xu, Xie L.;
- Sheng, Shihong;
- Jiang, Yusang;
- Liu, Yan;
- Han, Chenglong
Publication type:
Article
Safety of Guselkumab With and Without Prior Tumor Necrosis Factor Inhibitor Treatment: Pooled Results Across 4 Studies in Patients With Psoriatic Arthritis.
Published in:
Journal of Rheumatology, 2023, v. 50, n. 6, p. 769, doi. 10.3899/jrheum.220928
By:
- Rahman, Proton;
- Boehncke, Wolf-Henning;
- Mease, Philip J.;
- Gottlieb, Alice B.;
- McInnes, Iain B.;
- Shawi, May;
- Yanli Wang;
- Shihong Sheng;
- Kollmeier, Alexa P.;
- Theander, Elke;
- Yu, Jenny;
- Leibowitz, Evan;
- Marilise Marrache, A.;
- Coates, Laura C.
Publication type:
Article
Pooled Safety Results Through 1 Year of 2 Phase III Trials of Guselkumab in Patients With Psoriatic Arthritis.
Published in:
2021
By:
- Rahman, Proton;
- Ritchlin, Christopher T.;
- Helliwell, Philip S.;
- Boehncke, Wolf-Henning;
- Mease, Philip J.;
- Gottlieb, Alice B.;
- Kafka, Shelly;
- Kollmeier, Alexa P.;
- Hsia, Elizabeth C.;
- Xu, Xie L.;
- Shawi, May;
- Shihong Sheng;
- Agarwal, Prasheen;
- Bei Zhou;
- Ramachandran, Paraneedharan;
- Yanli Zhuang;
- McInnes, Iain B.;
- Sheng, Shihong;
- Zhou, Bei;
- Zhuang, Yanli
Publication type:
journal article
The effect of guselkumab on inhibiting radiographic progression in patients with active psoriatic arthritis: study protocol for APEX, a Phase 3b, multicenter, randomized, double-blind, placebo-controlled trial.
Published in:
Trials, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s13063-022-06945-y
By:
- Ritchlin, Christopher T.;
- Coates, Laura C.;
- Mease, Philip J.;
- van der Heijde, Désirée;
- Song, Jiao;
- Jiang, Yusang;
- Shawi, May;
- Kollmeier, Alexa P.;
- Rahman, Proton
Publication type:
Article
Continuous improvement through differential trajectories of individual minimal disease activity criteria with guselkumab in active psoriatic arthritis: post hoc analysis of a phase 3, randomized, double-blind, placebo-controlled study.
Published in:
BMC Rheumatology, 2024, v. 8, n. 1, p. 1, doi. 10.1186/s41927-024-00375-w
By:
- Coates, Laura C.;
- Rahman, Proton;
- Mease, Philip J.;
- Shawi, May;
- Rampakakis, Emmanouil;
- Kollmeier, Alexa P.;
- Xu, Xie L.;
- Chakravarty, Soumya D.;
- McInnes, Iain B.;
- Tam, Lai-Shan
Publication type:
Article
Guselkumab provides sustained domain-specific and comprehensive efficacy using composite indices in patients with active psoriatic arthritis.
Published in:
Rheumatology, 2023, v. 62, n. 2, p. 606, doi. 10.1093/rheumatology/keac375
By:
- Coates, Laura C;
- Ritchlin, Christopher T;
- Gossec, Laure;
- Helliwell, Philip S;
- Rahman, Proton;
- Kollmeier, Alexa P;
- Xu, Xie L;
- Shawi, May;
- Karyekar, Chetan S;
- Contré, Christine;
- Noël, Wim;
- Sheng, Shihong;
- Wang, Yanli;
- Xu, Stephen;
- Mease, Philip J
Publication type:
Article
Resolution of enthesitis by guselkumab and relationships to disease burden: 1-year results of two phase 3 psoriatic arthritis studies.
Published in:
Rheumatology, 2021, v. 60, n. 11, p. 5337, doi. 10.1093/rheumatology/keab285
By:
- McGonagle, Dennis;
- McInnes, Iain B;
- Deodhar, Atul;
- Schett, Georg;
- Shawi, May;
- Kafka, Shelly;
- Karyekar, Chetan S;
- Kollmeier, Alexa P;
- Hsia, Elizabeth C;
- Xu, Xie L;
- Sheng, Shihong;
- Agarwal, Prasheen;
- Zhou, Bei;
- Ritchlin, Christopher T;
- Rahman, Proton;
- Mease, Philip J
Publication type:
Article
Efficacy and Safety of Guselkumab, an Interleukin‐23p19–Specific Monoclonal Antibody, Through One Year in Biologic‐Naive Patients With Psoriatic Arthritis.
Published in:
Arthritis & Rheumatology, 2021, v. 73, n. 4, p. 604, doi. 10.1002/art.41553
By:
- McInnes, Iain B.;
- Rahman, Proton;
- Gottlieb, Alice B.;
- Hsia, Elizabeth C.;
- Kollmeier, Alexa P.;
- Chakravarty, Soumya D.;
- Xu, Xie L.;
- Subramanian, Ramanand A.;
- Agarwal, Prasheen;
- Sheng, Shihong;
- Jiang, Yusang;
- Zhou, Bei;
- Zhuang, Yanli;
- Heijde, Désirée;
- Mease, Philip J.
Publication type:
Article
Work Productivity and General Health Through 2 Years of Guselkumab Treatment in a Phase 3 Randomized Trial of Patients With Active Psoriatic Arthritis.
Published in:
Rheumatology & Therapy, 2024, v. 11, n. 2, p. 425, doi. 10.1007/s40744-024-00642-9
By:
- Curtis, Jeffrey R.;
- McInnes, Iain B.;
- Rahman, Proton;
- Gladman, Dafna D.;
- Peterson, Steven;
- Yang, Feifei;
- Adejoro, Oluwakayode;
- Kollmeier, Alexa P.;
- Shiff, Natalie J.;
- Han, Chenglong;
- Shawi, May;
- Tillett, William;
- Mease, Philip J.
Publication type:
Article
Efficacy of Guselkumab on Axial-Related Symptoms Through up to 2 Years in Adults with Active Psoriatic Arthritis in the Phase 3, Randomized, Placebo-Controlled DISCOVER-2 Study.
Published in:
Rheumatology & Therapy, 2023, v. 10, n. 6, p. 1637, doi. 10.1007/s40744-023-00592-8
By:
- Mease, Philip J.;
- Gladman, Dafna D.;
- Poddubnyy, Denis;
- Chakravarty, Soumya D.;
- Shawi, May;
- Kollmeier, Alexa P.;
- Xu, Xie L.;
- Xu, Stephen;
- Deodhar, Atul;
- Baraliakos, Xenofon
Publication type:
Article
Publisher Correction to: Collagen Turnover Biomarkers Associate with Active Psoriatic Arthritis and Decrease with Guselkumab Treatment in a Phase 3 Clinical Trial (DISCOVER-2).
Published in:
2022
By:
- Schett, Georg;
- Loza, Matthew J.;
- Palanichamy, Arumugam;
- FitzGerald, Oliver;
- Ritchlin, Christopher;
- Bay-Jensen, Anne-Christine;
- Nielsen, Signe Holm;
- Gao, Sheng;
- Hsia, Elizabeth C.;
- Kollmeier, Alexa P.;
- Xu, Xie L.;
- Baribaud, Frédéric;
- Sweet, Kristen
Publication type:
Correction Notice
Collagen Turnover Biomarkers Associate with Active Psoriatic Arthritis and Decrease with Guselkumab Treatment in a Phase 3 Clinical Trial (DISCOVER-2).
Published in:
Rheumatology & Therapy, 2022, v. 9, n. 4, p. 1017, doi. 10.1007/s40744-022-00444-x
By:
- Schett, Georg;
- Loza, Matthew J.;
- Palanichamy, Arumugam;
- FitzGerald, Oliver;
- Ritchlin, Christopher;
- Bay-Jensen, Anne-Christine;
- Nielsen, Signe Holm;
- Gao, Sheng;
- Hsia, Elizabeth C.;
- Kollmeier, Alexa P.;
- Xu, Xie L.;
- Baribaud, Frédéric;
- Sweet, Kristen
Publication type:
Article
The Effect of Guselkumab on Work Productivity in Biologic-Naïve Patients with Active Psoriatic Arthritis Through Week 52 of the Phase 3, Randomized, Placebo-Controlled DISCOVER-2 Trial.
Published in:
2022
By:
- Curtis, Jeffrey R.;
- McInnes, Iain B.;
- Rahman, Proton;
- Gladman, Dafna D.;
- Peterson, Steven;
- Agarwal, Prasheen;
- Yang, Feifei;
- Kollmeier, Alexa P.;
- Hsia, Elizabeth C.;
- Shiff, Natalie J.;
- Zhou, Bei;
- Han, Chenglong;
- Shawi, May;
- Tillett, William;
- Mease, Philip J.
Publication type:
journal article
The Effect of Guselkumab on General Health State in Biologic-Naïve Patients with Active Psoriatic Arthritis Through Week 52 of the Phase 3, Randomized, Placebo-Controlled DISCOVER-2 Trial.
Published in:
2022
By:
- Curtis, Jeffrey R.;
- McInnes, Iain B.;
- Rahman, Proton;
- Gladman, Dafna D.;
- Yang, Feifei;
- Peterson, Steven;
- Agarwal, Prasheen;
- Kollmeier, Alexa P.;
- Hsia, Elizabeth C.;
- Han, Chenglong;
- Shiff, Natalie J.;
- Shawi, May;
- Tillett, William;
- Mease, Philip J.
Publication type:
journal article
Modulation of Interleukin‐23 Signaling With Guselkumab in Biologic‐Naive Patients Versus Tumor Necrosis Factor Inhibitor–Inadequate Responders With Active Psoriatic Arthritis.
Published in:
Arthritis & Rheumatology, 2024, v. 76, n. 6, p. 894, doi. 10.1002/art.42803
By:
- Siebert, Stefan;
- Coates, Laura C.;
- Schett, Georg;
- Raychaudhuri, Siba P.;
- Chen, Warner;
- Gao, Sheng;
- Seridi, Loqmane;
- Chakravarty, Soumya D.;
- Shawi, May;
- Lavie, Frederic;
- Sharaf, Mohamed;
- Zimmermann, Miriam;
- Kollmeier, Alexa P.;
- Xu, Xie L.;
- Rahman, Proton;
- Mease, Philip J.;
- Deodhar, Atul
Publication type:
Article
Long‐Term Efficacy and Safety of Guselkumab, a Monoclonal Antibody Specific to the p19 Subunit of Interleukin‐23, Through Two Years: Results From a Phase III, Randomized, Double‐Blind, Placebo‐Controlled Study Conducted in Biologic‐Naive Patients With Active Psoriatic Arthritis
Published in:
Arthritis & Rheumatology, 2022, v. 74, n. 3, p. 475, doi. 10.1002/art.42010
By:
- McInnes, Iain B.;
- Rahman, Proton;
- Gottlieb, Alice B.;
- Hsia, Elizabeth C.;
- Kollmeier, Alexa P.;
- Xu, Xie L.;
- Jiang, Yusang;
- Sheng, Shihong;
- Shawi, May;
- Chakravarty, Soumya D.;
- van der Heijde, Désirée;
- Mease, Philip J.
Publication type:
Article
Long-Term Safety of Guselkumab in Patients with Psoriatic Disease: An Integrated Analysis of Eleven Phase II/III Clinical Studies in Psoriasis and Psoriatic Arthritis.
Published in:
Drug Safety, 2024, v. 47, n. 1, p. 39, doi. 10.1007/s40264-023-01361-w
By:
- Strober, Bruce;
- Coates, Laura C.;
- Lebwohl, Mark G.;
- Deodhar, Atul;
- Leibowitz, Evan;
- Rowland, Katelyn;
- Kollmeier, Alexa P.;
- Miller, Megan;
- Wang, Yanli;
- Li, Shu;
- Chakravarty, Soumya D.;
- Chan, Daphne;
- Shawi, May;
- Yang, Ya-Wen;
- Thaҫi, Diamant;
- Rahman, Proton
Publication type:
Article
Guselkumab demonstrated an independent treatment effect in reducing fatigue after adjustment for clinical response—results from two phase 3 clinical trials of 1120 patients with active psoriatic arthritis.
Published in:
Arthritis Research & Therapy, 2021, v. 23, n. 1, p. 1, doi. 10.1186/s13075-021-02554-3
By:
- Rahman, Proton;
- Mease, Philip J.;
- Helliwell, Philip S.;
- Deodhar, Atul;
- Gossec, Laure;
- Kavanaugh, Arthur;
- Kollmeier, Alexa P.;
- Hsia, Elizabeth C.;
- Zhou, Bei;
- Lin, Xiwu;
- Shawi, May;
- Karyekar, Chetan S.;
- Han, Chenglong
Publication type:
Article

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