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A Comparative Study of the Rapid (I Kr) and Slow (I Ks) Delayed Rectifier Potassium Currents in Undiseased Human, Dog, Rabbit, and Guinea Pig Cardiac Ventricular Preparations.
- Published in:
- Pharmaceuticals (14248247), 2024, v. 17, n. 8, p. 1091, doi. 10.3390/ph17081091
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- Publication type:
- Article
A novel transgenic rabbit model with reduced repolarization reserve: long QT syndrome caused by a dominant-negative mutation of the KCNE1 gene.
- Published in:
- 2016
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- Publication type:
- journal article
Selective Na(+) /Ca(2+) exchanger inhibition prevents Ca(2+) overload-induced triggered arrhythmias.
- Published in:
- 2014
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- Publication type:
- journal article
Selective Na<sup>+</sup>/ Ca<sup>2+</sup> exchanger inhibition prevents Ca<sup>2+</sup> overload-induced triggered arrhythmias.
- Published in:
- British Journal of Pharmacology, 2014, v. 171, n. 24, p. 5665, doi. 10.1111/bph.12867
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- Publication type:
- Article
The Cardiac Pacemaker Story—Fundamental Role of the Na<sup>+</sup>/Ca<sup>2+</sup> Exchanger in Spontaneous Automaticity.
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- Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00516
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- Publication type:
- Article
Novel Na<sup>+</sup>/Ca<sup>2+</sup> Exchanger Inhibitor ORM-10962 Supports Coupled Function of Funny-Current and Na<sup>+</sup>/Ca<sup>2+</sup> Exchanger in Pacemaking of Rabbit Sinus Node Tissue.
- Published in:
- Frontiers in Pharmacology, 2020, p. 1, doi. 10.3389/fphar.2019.01632
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- Publication type:
- Article
Diclofenac Prolongs Repolarization in Ventricular Muscle with Impaired Repolarization Reserve.
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- PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0053255
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- Publication type:
- Article
Muscarinic agonists inhibit the ATP-dependent potassium current and suppress the ventricle–Purkinje action potential dispersion.
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- Canadian Journal of Physiology & Pharmacology, 2021, v. 99, n. 2, p. 247, doi. 10.1139/cjpp-2020-0408
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- Publication type:
- Article
Antiarrhythmic and cardiac electrophysiological effects of SZV-270, a novel compound with combined Class I/B and Class III effects, in rabbits and dogs.
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- Canadian Journal of Physiology & Pharmacology, 2021, v. 99, n. 1, p. 89, doi. 10.1139/cjpp-2020-0412
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- Publication type:
- Article
The investigation of the cellular electrophysiological and antiarrhythmic effects of a novel selective sodium-calcium exchanger inhibitor, GYKB-6635, in canine and guinea-pig hearts<sup>1</sup>.
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- Canadian Journal of Physiology & Pharmacology, 2016, v. 94, n. 10, p. 1090, doi. 10.1139/cjpp-2015-0566
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- Publication type:
- Article
Identification and functional characterisation of a novel KCNJ2 mutation, Val302del, causing Andersen-Tawil syndrome.
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- Canadian Journal of Physiology & Pharmacology, 2015, v. 93, n. 7, p. 569, doi. 10.1139/cjpp-2014-0527
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- Publication type:
- Article
L-364,373 (R-L3) enantiomers have opposite modulating effects on I<sub>Ks</sub> in mammalian ventricular myocytes.
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- Canadian Journal of Physiology & Pharmacology, 2013, v. 91, n. 8, p. 586, doi. 10.1139/cjpp-2012-0407
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- Publication type:
- Article
The development of L-type Ca<sup>2+</sup> current mediated alternans does not depend on the restitution slope in canine ventricular myocardium.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-95299-7
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- Publication type:
- Article
Author Correction: Increased Ca2+ content of the sarcoplasmic reticulum provides arrhythmogenic trigger source in swimming-induced rat athlete's heart model.
- Published in:
- 2021
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- Publication type:
- Correction Notice
Increased Ca<sup>2+</sup> content of the sarcoplasmic reticulum provides arrhythmogenic trigger source in swimming-induced rat athlete's heart model.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-76496-2
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- Publication type:
- Article
The Effect of a Novel Highly Selective Inhibitor of the Sodium/Calcium Exchanger (NCX) on Cardiac Arrhythmias in In Vitro and In Vivo Experiments.
- Published in:
- PLoS ONE, 2016, v. 11, n. 11, p. 1, doi. 10.1371/journal.pone.0166041
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- Publication type:
- Article
Evaluation of Possible Proarrhythmic Potency: Comparison of the Effect of Dofetilide, Cisapride, Sotalol, Terfenadine, and Verapamil on hERG and Native I<sub>Kr</sub> Currents and on Cardiac Action Potential.
- Published in:
- Toxicological Sciences, 2019, v. 168, n. 2, p. 365, doi. 10.1093/toxsci/kfy299
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- Publication type:
- Article
Ionic mechanisms limiting cardiac repolarization reserve in humans compared to dogs.
- Published in:
- Journal of Physiology, 2013, v. 591, n. 17, p. 4189, doi. 10.1113/jphysiol.2013.261198
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- Publication type:
- Article
The reverse mode of the Na<sup>+</sup>/Ca<sup>2+</sup> exchanger contributes to the pacemaker mechanism in rabbit sinus node cells.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-25574-8
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- Publication type:
- Article
In vivo and cellular antiarrhythmic and cardiac electrophysiological effects of desethylamiodarone in dog cardiac preparations.
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- British Journal of Pharmacology, 2022, v. 179, n. 13, p. 3382, doi. 10.1111/bph.15812
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- Publication type:
- Article
Discovery and characterization of ORM‐11372, a novel inhibitor of the sodium‐calcium exchanger with positive inotropic activity.
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- British Journal of Pharmacology, 2020, v. 177, n. 24, p. 5534, doi. 10.1111/bph.15257
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- Publication type:
- Article
Cardiac electrophysiological remodeling associated with enhanced arrhythmia susceptibility in a canine model of elite exercise.
- Published in:
- eLife, 2023, p. 1, doi. 10.7554/eLife.80710
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- Publication type:
- Article
Properties of the transient outward, ultra-rapid delayed rectifier and acetylcholine-sensitive potassium currents in isolated atrial myocytes from dogs: sinus rhythm and tachypaced model of permanent atrial fibrillation.
- Published in:
- 2011
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- Publication type:
- Abstract
Effects of diclofenac on ventricular muscle repolarization: proarrhythmic implications.
- Published in:
- 2011
- By:
- Publication type:
- Abstract
The Inhibition of the Small-Conductance Ca 2+ -Activated Potassium Channels Decreases the Sinus Node Pacemaking during Beta-Adrenergic Activation.
- Published in:
- Pharmaceuticals (14248247), 2022, v. 15, n. 3, p. 313, doi. 10.3390/ph15030313
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- Publication type:
- Article