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Pharmacokinetics of a continuous intravenous infusion of hydromorphone in healthy dogs.
Published in:
Frontiers in Veterinary Science, 2024, p. 1, doi. 10.3389/fvets.2024.1362730
By:
- Wimbish, Candace;
- Lynch, Alex M.;
- Knych, Heather K.;
- Yu Ueda;
- Messenger, Kristen M.
Publication type:
Article
Plasma concentrations of buprenorphine administered via matrix-type transdermal patches applied at three different anatomical locations in healthy adult horses.
Published in:
Frontiers in Pain Research, 2024, p. 1, doi. 10.3389/fpain.2024.1390322
By:
- Paranjape, Vaidehi V.;
- Knych, Heather K.;
- Berghaus, Londa J.;
- Giancola, Shyla;
- Cathcart, Jessica;
- Reed, Rachel A.
Publication type:
Article
The pharmacokinetics and pharmacodynamics of fentanyl administered via transdermal patch in horses.
Published in:
Frontiers in Pain Research, 2024, p. 1, doi. 10.3389/fpain.2024.1373759
By:
- Reed, Rachel A.;
- Berghaus, Londa J.;
- Reynolds, Rose M.;
- Holmes, Brittany T.;
- Krikorian, Anna M.;
- Sakai, Daniel M.;
- Yushun Ishikawa;
- Knych, Heather K.
Publication type:
Article
Evaluation of physical variables, thermal nociceptive threshold testing and pharmacokinetics during placement of transdermal buprenorphine matrix-type patch in healthy adult horses.
Published in:
Frontiers in Pain Research, 2024, p. 1, doi. 10.3389/fpain.2024.1373555
By:
- Paranjape, Vaidehi V.;
- Knych, Heather K.;
- Berghaus, Londa J.;
- Cathcart, Jessica;
- Giancola, Shyla;
- Craig, Hannah;
- James, Caroline;
- Saksena, Siddharth;
- Reed, Rachel A.
Publication type:
Article
Transdermal Flunixin Meglumine as a Pain Relief in Donkeys: A Pharmacokinetics Pilot Study.
Published in:
Metabolites (2218-1989), 2023, v. 13, n. 7, p. 776, doi. 10.3390/metabo13070776
By:
- McLean, Amy K.;
- Falt, Tara;
- Abdelfattah, Essam M.;
- Middlebrooks, Brittany;
- Gretler, Sophie;
- Spier, Sharon;
- Turoff, David;
- Navas Gonzalez, Francisco Javier;
- Knych, Heather K.
Publication type:
Article
Oral cytarabine ocfosfate pharmacokinetics and assessment of leukocyte biomarkers in normal dogs.
Published in:
Journal of Veterinary Internal Medicine, 2023, v. 37, n. 6, p. 2429, doi. 10.1111/jvim.16842
By:
- Zwueste, Danielle M.;
- Vernau, Karen M.;
- Vernau, William;
- Pypendop, Bruno H.;
- Knych, Heather K.;
- Rodrigues, Carlos A.;
- Kol, Amir;
- Questa, Maria;
- Dickinson, Peter J.
Publication type:
Article
Pharmacokinetics and efficacy of intravenous famotidine in adult cattle.
Published in:
Journal of Veterinary Internal Medicine, 2018, v. 32, n. 3, p. 1283, doi. 10.1111/jvim.15080
By:
- Balcomb, Christie C.;
- Heller, Meera C.;
- Chigerwe, Munashe;
- Knych, Heather K.;
- Meyer, Allison M.
Publication type:
Article
Longitudinal evaluation of fentanyl concentrations in equine plasma and synovial fluid following application of transdermal fentanyl patches over one carpal joint.
Published in:
Veterinary Surgery, 2023, v. 52, n. 8, p. 1150, doi. 10.1111/vsu.13990
By:
- Ortega McCormack, John J.;
- Reed, Rachel A.;
- Epstein, Kira L.;
- Camus, Melinda S.;
- Knych, Heather K.
Publication type:
Article
Pharmacokinetics and pharmacodynamics of meperidine after intramuscular and subcutaneous administration in horses.
Published in:
Veterinary Surgery, 2021, v. 50, n. 2, p. 410, doi. 10.1111/vsu.13545
By:
- Hanafi, Amanda L.;
- Reed, Rachel A.;
- Trenholme, Heather N.;
- Sakai, Daniel M.;
- Ryan, Clare A.;
- Barletta, Michele;
- Quandt, Jane E.;
- Knych, Heather K.
Publication type:
Article
Preliminary study of the stability of dexamethasone when added to commercial veterinary ear cleaners over a 90 day period.
Published in:
Veterinary Dermatology, 2021, v. 32, n. 2, p. 168, doi. 10.1111/vde.12924
By:
- Emery, Carolyn B.;
- Outerbridge, Catherine A.;
- Knych, Heather K.;
- Lam, Andrea T.H.;
- Gomez‐Vazquez, Jose P.;
- White, Stephen D.
Publication type:
Article
Pharmacokinetics of a Single Dose of Oral Meloxicam in Rehabilitated Wild Brown Pelicans (Pelecanus occidentalis).
Published in:
Journal of Avian Medicine & Surgery, 2020, v. 34, n. 4, p. 329, doi. 10.1647/1082-6742-34.4.329
By:
- Horgan, Molly D.;
- Knych, Heather K.;
- Siksay, Sharon E.;
- Duerr, Rebecca S.
Publication type:
Article
Pharmacokinetics of a Sustained Release Formulation of Buprenorphine After Intramuscular and Subcutaneous Administration to American Kestrels ( Falco sparverius).
Published in:
Journal of Avian Medicine & Surgery, 2017, v. 31, n. 2, p. 102, doi. 10.1647/2015-155
By:
- Guzman, David Sanchez-Migallon;
- Knych, Heather K.;
- Olsen, Glenn H.;
- Paul-Murphy, Joanne R.
Publication type:
Article
Preliminary study of the pharmacokinetics, tissue distribution, and behavioral and select physiological effects of morphine 6-glucuronide (M6G) following intravenous administration to horses.
Published in:
Canadian Journal of Veterinary Research / Revue Canadienne de Recherche Vétérinaire, 2022, v. 86, n. 3, p. 172
By:
- Hamamoto-Hardman, Briana D.;
- Steffey, Eugene P.;
- Seminoff, Kelsey;
- McKemie, Daniel S.;
- Kass, Philip;
- Knych, Heather K.
Publication type:
Article
Pharmacokinetics and pharmacodynamics of intra-articular isoflupredone following administration to horses with lipopolysaccharide-induced synovitis.
Published in:
BMC Veterinary Research, 2022, v. 18, p. 1, doi. 10.1186/s12917-022-03537-5
By:
- Knych, Heather K.;
- Weiner, Daniel;
- Harrison, Linda;
- McKemie, Daniel S.
Publication type:
Article
Pharmacokinetics, adverse effects and effects on thermal nociception following administration of three doses of codeine to horses.
Published in:
BMC Veterinary Research, 2022, v. 18, n. 1, p. 1, doi. 10.1186/s12917-022-03299-0
By:
- Knych, Heather K.;
- Stucker, Kristen;
- Gretler, Sophie R.;
- Kass, Philip H.;
- McKemie, Daniel S.
Publication type:
Article
Differential expression of skeletal muscle genes following administration of clenbuterol to exercised horses.
Published in:
BMC Genomics, 2016, v. 17, p. 1, doi. 10.1186/s12864-016-2945-2
By:
- Knych, Heather K.;
- Harrison, Linda M.;
- Steinmetz, Stacy J.;
- Chouicha, Nadira;
- Kass, Phil H.
Publication type:
Article
Anesthetic Pharmacology of the Mint Extracts L-Carvone and Methyl Salicylate.
Published in:
Pharmacology, 2022, v. 107, n. 3/4, p. 167, doi. 10.1159/000520762
By:
- Brosnan, Robert J.;
- Ramos, Kimberly;
- Aguiar, Antonio Jose de Araujo;
- Cenani, Alessia;
- Knych, Heather K.
Publication type:
Article
In vitro and in vivo GABA<sub>A</sub> Receptor Interaction of the Propanidid Metabolite 4-(2-[Diethylamino]-2-Oxoethoxy)-3-Methoxy-Benzeneacetic Acid.
Published in:
Pharmacology, 2019, v. 103, n. 1/2, p. 10, doi. 10.1159/000493753
By:
- Cenani, Alessia;
- Brosnan, Robert J.;
- Knych, Heather K.
Publication type:
Article
Pharmacokinetics and thermal anti-nociceptive effects of oral morphine in horses.
Published in:
Frontiers in Veterinary Science, 2024, p. 01, doi. 10.3389/fvets.2024.1461648
By:
- Knych, Heather K.;
- Steinmetz, Stacy J.;
- Traynham, Megan L.;
- McKemie, Daniel S.;
- Kass, Philip H.
Publication type:
Article
Systemic absorption of triamcinolone acetonide is increased from intrasynovial versus extrasynovial sites and induces hyperglycemia, hyperinsulinemia, and suppression of the hypothalamic-pituitary-adrenal axis.
Published in:
Frontiers in Veterinary Science, 2024, p. 1, doi. 10.3389/fvets.2024.1388470
By:
- Hallowel, Kimberly L.;
- Dembek, Katarzyna;
- Horne, Caitlyn R.;
- Knych, Heather K.;
- Messenger, Kristen M.;
- Schnabel, Lauren V.
Publication type:
Article
Detection and residence time of bisphosphonates in bone of horses.
Published in:
Journal of Veterinary Diagnostic Investigation, 2022, v. 34, n. 1, p. 23, doi. 10.1177/10406387211050049
By:
- Knych, Heather K.;
- Janes, Jennifer;
- Kennedy, Laura;
- McKemie, Daniel S.;
- Arthur, Rick M.;
- Samol, Monika A.;
- Uzal, Francisco A.;
- Scollay, Mary
Publication type:
Article
Direct Umbilical Vein Injection of Epinephrine with Cut-Cord Milking in an Ovine Model of Neonatal Resuscitation.
Published in:
Children, 2024, v. 11, n. 5, p. 527, doi. 10.3390/children11050527
By:
- Vali, Payam;
- Chen, Peggy;
- Giusto, Evan;
- Lesneski, Amy;
- Hardie, Morgan E.;
- Knych, Heather K.;
- Sankaran, Deepika;
- Alhassen, Ziad;
- Joudi, Houssam M.;
- Lakshminrusimha, Satyan
Publication type:
Article
Effect of a Larger Flush Volume on Bioavailability and Efficacy of Umbilical Venous Epinephrine during Neonatal Resuscitation in Ovine Asphyxial Arrest.
Published in:
Children, 2021, v. 8, n. 6, p. 1, doi. 10.3390/children8060464
By:
- Sankaran, Deepika;
- Vali, Payam;
- Chandrasekharan, Praveen;
- Chen, Peggy;
- Gugino, Sylvia F.;
- Koenigsknecht, Carmon;
- Helman, Justin;
- Nair, Jayasree;
- Mathew, Bobby;
- Rawat, Munmun;
- Nielsen, Lori;
- Lesneski, Amy L.;
- Hardie, Morgan E.;
- Alhassen, Ziad;
- Joudi, Houssam M.;
- Giusto, Evan M.;
- Zeinali, Lida;
- Knych, Heather K.;
- Weiner, Gary M.;
- Lakshminrusimha, Satyan
Publication type:
Article
Meperidine pharmacokinetics and effects on physiologic parameters and thermal threshold following intravenous administration of three doses to horses.
Published in:
BMC Veterinary Research, 2020, v. 16, n. 1, p. N.PAG, doi. 10.1186/s12917-020-02564-4
By:
- Hamamoto-Hardman, Briana D.;
- Steffey, Eugene P.;
- McKemie, Daniel S.;
- Kass, Philip H.;
- Knych, Heather K.
Publication type:
Article
Drug content on receipt and over time for compounded formulations of famciclovir.
Published in:
Journal of Feline Medicine & Surgery, 2021, v. 23, n. 6, p. 519, doi. 10.1177/1098612X20961046
By:
- Johnson, Lynelle R;
- Weaver, Phoebe G;
- Forsythe, Lauren E;
- Thomasy, Sara M;
- Knych, Heather K
Publication type:
Article
Pharmacokinetics and metabolism of lidocaine HCl 2% with epinephrine in horses following a palmar digital nerve block.
Published in:
BMC Veterinary Research, 2023, v. 19, n. 1, p. 1, doi. 10.1186/s12917-023-03787-x
By:
- Knych, Heather K.;
- Katzman, Scott;
- McKemie, Daniel S.;
- Arthur, Rick M.;
- Blea, Jeff
Publication type:
Article
Ketoprofen in horses: Metabolism, pharmacokinetics, and effects on inflammatory biomarkers.
Published in:
Drug Testing & Analysis, 2024, v. 16, n. 3, p. 289, doi. 10.1002/dta.3543
By:
- Knych, Heather K.;
- McKemie, Daniel S.;
- Kass, Philip H.;
- Stanley, Scott D.;
- Blea, Jeff
Publication type:
Article
Pharmacokinetics and effects on arachidonic acid metabolism of low doses of cannabidiol following oral administration to horses.
Published in:
Drug Testing & Analysis, 2021, v. 13, n. 7, p. 1305, doi. 10.1002/dta.3028
By:
- Ryan, Declan;
- McKemie, Dan S.;
- Kass, Philip H.;
- Puschner, Birgit;
- Knych, Heather K.
Publication type:
Article
Serum concentrations, pharmacokinetic/pharmacodynamic modeling, and effects of dexamethasone on inflammatory mediators following intravenous and oral administration to exercised horses.
Published in:
Drug Testing & Analysis, 2020, v. 12, n. 8, p. 1087, doi. 10.1002/dta.2862
By:
- Knych, Heather K.;
- Weiner, Daniel;
- Arthur, Rick M.;
- Baden, Russell;
- McKemie, Daniel S.;
- Kass, Philip H.
Publication type:
Article
Detection, pharmacokinetics, and selected pharmacodynamic effects of methamphetamine following a single transmucosal and intravenous administration to exercised Thoroughbred horses.
Published in:
Drug Testing & Analysis, 2019, v. 11, n. 9, p. 1431, doi. 10.1002/dta.2661
By:
- Knych, Heather K.;
- Arthur, Rick M.;
- Kanarr, Kirsten L.;
- McKemie, Dan S.;
- Kass, Philip H.
Publication type:
Article
Phenylbutazone blood and urine concentrations, pharmacokinetics, and effects on biomarkers of inflammation in horses following intravenous and oral administration of clinical doses.
Published in:
Drug Testing & Analysis, 2019, v. 11, n. 6, p. 792, doi. 10.1002/dta.2553
By:
- Knych, Heather K.;
- Arthur, Rick M.;
- McKemie, Dan S.;
- Seminoff, Kelsey;
- Hamamoto‐Hardman, Briana;
- Kass, Philip H.
Publication type:
Article
L‐ and D‐threo ethylphenidate concentrations, pharmacokinetics, and pharmacodynamics in horses.
Published in:
Drug Testing & Analysis, 2018, v. 10, n. 10, p. 1508, doi. 10.1002/dta.2408
By:
- Knych, Heather K.;
- McKemie, Dan S.;
- Seminoff, Kelsey;
- Hartmann, Petra;
- Hovda, Lynn;
- Benson, Dionne
Publication type:
Article
Detection and pharmacokinetics of grapiprant following oral administration to exercised Thoroughbred horses.
Published in:
Drug Testing & Analysis, 2018, v. 10, n. 8, p. 1237, doi. 10.1002/dta.2378
By:
- Knych, Heather K.;
- Seminoff, Kelsey;
- McKemie, Dan S.
Publication type:
Article
Pharmacokinetics of betamethasone in plasma, urine, and synovial fluid following intra-articular administration to exercised thoroughbred horses.
Published in:
Drug Testing & Analysis, 2017, v. 9, n. 9, p. 1385, doi. 10.1002/dta.2170
By:
- Knych, Heather K.;
- Stanley, Scott D.;
- Harrison, Linda M.;
- Mckemie, Daniel S.
Publication type:
Article
Pharmacokinetics and pharmacodynamics of meldonium in exercised thoroughbred horses.
Published in:
Drug Testing & Analysis, 2017, v. 9, n. 9, p. 1392, doi. 10.1002/dta.2214
By:
- Knych, Heather K.;
- Stanley, Scott D.;
- McKemie, Dan S.;
- Arthur, Rick M.;
- Bondesson, Ulf;
- Hedeland, Mikael;
- Thevis, Mario;
- Kass, Philip H.
Publication type:
Article
Pharmacokinetics of dextromethorphan and its metabolites in horses following a single oral administration.
Published in:
Drug Testing & Analysis, 2017, v. 9, n. 6, p. 880, doi. 10.1002/dta.2060
By:
- Corado, Carley R.;
- McKemie, Daniel S.;
- Knych, Heather K.
Publication type:
Article
Pharmacokinetic and pharmacodynamics of xylazine administered to exercised thoroughbred horses.
Published in:
Drug Testing & Analysis, 2017, v. 9, n. 5, p. 713, doi. 10.1002/dta.2047
By:
- Knych, Heather K.;
- Stanley, Scott D.;
- McKemie, Daniel S.;
- Arthur, Rick M.;
- Kass, Phil H.
Publication type:
Article
Disposition of isoflupredone acetate in plasma, urine and synovial fluid following intra-articular administration to exercised Thoroughbred horses.
Published in:
Drug Testing & Analysis, 2016, v. 8, n. 1, p. 142, doi. 10.1002/dta.1834
By:
- Knych, Heather K.;
- Harrison, Linda M.;
- White, Alexandria;
- McKemie, Daniel S.
Publication type:
Article
Transcriptomic Markers of Recombinant Human Erythropoietin Micro-Dosing in Thoroughbred Horses.
Published in:
Genes, 2021, v. 12, n. 12, p. 1874, doi. 10.3390/genes12121874
By:
- Dahlgren, Anna R.;
- Knych, Heather K.;
- Arthur, Rick M.;
- Durbin-Johnson, Blythe P.;
- Finno, Carrie J.
Publication type:
Article
Morphine in donkeys: Antinociceptive effect and preliminary pharmacokinetics.
Published in:
Equine Veterinary Journal, 2023, v. 55, n. 6, p. 1086, doi. 10.1111/evj.13912
By:
- Maney, Jill K.;
- Dzikiti, Brighton T.;
- Escobar, Andre;
- Knych, Heather K.;
- Bennett, Rachel C.
Publication type:
Article
Ocular penetration of oral acetaminophen in horses.
Published in:
Equine Veterinary Journal, 2023, v. 55, n. 5, p. 899, doi. 10.1111/evj.13902
By:
- Peraza, Jacky;
- Hector, Rachel C.;
- Lee, Sera;
- Terhaar, Hannah M.;
- Knych, Heather K.;
- Wotman, Kathryn L.
Publication type:
Article
Clodronate detection and effects on markers of bone resorption are prolonged following a single administration to horses.
Published in:
Equine Veterinary Journal, 2023, v. 55, n. 4, p. 696, doi. 10.1111/evj.13866
By:
- Knych, Heather K.;
- Finno, Carrie J.;
- Katzman, Scott;
- Ryan, Declan;
- McKemie, Daniel S.;
- Kass, Philip H.;
- Arthur, Rick M.
Publication type:
Article
Pharmacokinetics and anti‐inflammatory effects of flunixin meglumine as a sole agent and in combination with phenylbutazone in exercised Thoroughbred horses.
Published in:
Equine Veterinary Journal, 2021, v. 53, n. 1, p. 102, doi. 10.1111/evj.13260
By:
- Knych, Heather K.;
- Arthur, Rick M.;
- McKemie, Daniel S.;
- Baden, Russell W.;
- Seminoff, Kelsey;
- Kass, Philip H.
Publication type:
Article
Pharmacokinetics and pharmacodynamics of clodronate disodium evaluated in plasma, synovial fluid and urine.
Published in:
Equine Veterinary Journal, 2020, v. 52, n. 5, p. 725, doi. 10.1111/evj.13244
By:
- Krueger, Clarisa R.;
- Mitchell, Colin F.;
- Leise, Britta S.;
- Knych, Heather K.
Publication type:
Article
Pharmacokinetics of intraarticular liposomal amphotericin B in goats (Capra aegagrus hircus).
Published in:
Journal of Veterinary Pharmacology & Therapeutics, 2024, v. 47, n. 4, p. 252, doi. 10.1111/jvp.13442
By:
- Smith, Joe S.;
- Malla, Grace D.;
- Garcia, Jessica D.;
- Gebert, Jessica E.;
- Noll, Charlene V.;
- Mulon, Pierre‐Yves;
- Knych, Heather K.
Publication type:
Article
Effect of clodronate on gene expression in the peripheral blood of horses.
Published in:
Journal of Veterinary Pharmacology & Therapeutics, 2024, v. 47, n. 3, p. 187, doi. 10.1111/jvp.13424
By:
- Wilcox, Callie V.;
- Knych, Heather K.;
- Katzman, Scott A.;
- Arthur, Rick M.;
- Rodriguez, Veronika;
- Finno, Carrie J.
Publication type:
Article
Pharmacokinetics and effects of codeine in combination with acetaminophen on thermal nociception in horses.
Published in:
Journal of Veterinary Pharmacology & Therapeutics, 2023, v. 46, n. 5, p. 311, doi. 10.1111/jvp.13126
By:
- Tueshaus, Tisa;
- McKemie, Daniel S.;
- Kanarr, Kirsten;
- Kass, Philip H.;
- Knych, Heather K.
Publication type:
Article
Concentrations, pharmacokinetics and selected pharmacodynamics of morphine and its active metabolites following oral administration to horses.
Published in:
Journal of Veterinary Pharmacology & Therapeutics, 2023, v. 46, n. 4, p. 238, doi. 10.1111/jvp.13122
By:
- Poth, Meghan K. M.;
- McKemie, Daniel S.;
- Traynham, Megan;
- Kass, Philip H.;
- Knych, Heather K.
Publication type:
Article
Pharmacokinetics of intra‐articular buprenorphine in horses with lipopolysaccharide‐induced synovitis.
Published in:
Journal of Veterinary Pharmacology & Therapeutics, 2023, v. 46, n. 4, p. 229, doi. 10.1111/jvp.13119
By:
- Castro‐Cuellar, Gabriel;
- Cremer, Jeannette;
- Queiroz‐Williams, Patricia;
- Knych, Heather K.;
- Leise, Britta S.
Publication type:
Article
Pharmacokinetics of intramuscular maropitant in pigs (Sus scrofa domesticus).
Published in:
Journal of Veterinary Pharmacology & Therapeutics, 2023, v. 46, n. 3, p. 158, doi. 10.1111/jvp.13120
By:
- Smith, Joe S.;
- Gebert, Jessica E.;
- Ebner, Lisa S.;
- Bennett, Kailee O.;
- Collins, Rebecca J.;
- Hampton, Chiara E.;
- Kleine, Stephanie A.;
- Mulon, Pierre‐Yves;
- Smith, Christopher K.;
- Seddighi, Reza;
- Bussieres, Genevieve;
- Mochel, Jonathan P.;
- Knych, Heather K.
Publication type:
Article

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