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Atopic dermatitis: A tale of two distinct pathomechanisms that make you itch.
Published in:
European Journal of Immunology, 2016, v. 46, n. 11, p. 2512, doi. 10.1002/eji.201646708
By:
- Knol, Edward F.;
- Hijnen, DirkJan
Publication type:
Article
Transforming growth factor-β inhibits human antigen-specific CD4+ T cell proliferation without modulating the cytokine response.
Published in:
International Immunology, 2003, v. 15, n. 12, p. 1495
By:
- Machteld M. Tiemessen;
- Steffen Kunzmann;
- Carsten B. Schmidt-Weber;
- Johan Garssen;
- Carla A. F. M. Bruijnzeel-Koomen;
- Edward F. Knol;
- Els Van Hoffen
Publication type:
Article
IgG4-Bestimmungen gegen Nahrungsmittel werden nicht zur Diagnostik empfohlen: Positionspapier der European Academy of Allergology and Clinical Immunology (EAACI)1 / Testing for IgG4 against foods is not recommended as a diagnostic tool: EAACI Task Force report
Published in:
Journal of Laboratory Medicine / Laboratoriums Medizin, 2010, v. 34, n. 4, p. 171, doi. 10.1515/JLM.2010.035
By:
- Stapel, Steven O.;
- Asero, Ricardo;
- Ballmer-Weber, Barbara K.;
- Knol, Edward F.;
- Strobel, Stephan;
- Vieths, Stefan;
- Kleine-Tebbe, Jörg
Publication type:
Article
Enzymes involved in the conversion of arachidonic acid to eicosanoids in the skin of atopic dogs.
Published in:
Experimental Dermatology, 2010, v. 19, n. 8, p. e317, doi. 10.1111/j.1600-0625.2009.01037.x
By:
- Schlotter, Yvette M.;
- Riemers, Frank M.;
- Rutten, Victor P.M.G.;
- Knol, Edward F.;
- Willemse, Ton
Publication type:
Article
Non-Digestible Oligosaccharides Can Suppress Basophil Degranulation in Whole Blood of Peanut-Allergic Patients.
Published in:
Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.01265
By:
- Hayen, Simone M.;
- den Hartog Jager, Constance F.;
- Knulst, André C.;
- Knol, Edward F.;
- Garssen, Johan;
- Willemsen, Linette E. M.;
- Otten, Henny G.
Publication type:
Article
The Immune Cell Composition in Barrett's Metaplastic Tissue Resembles That in Normal Duodenal Tissue.
Published in:
PLoS ONE, 2012, v. 7, n. 4, p. 1, doi. 10.1371/journal.pone.0033899
By:
- Lind, Alexandra;
- Siersema, Peter D.;
- Kusters, Johannes G.;
- Van der Linden, Jan A. M.;
- Knol, Edward F.;
- Koenderman, Leo
Publication type:
Article
Enzymatic Treatment of Whey Proteins in Cow's Milk Results in Differential Inhibition of IgE-Mediated Mast Cell Activation Compared to T-Cell Activation.
Published in:
International Archives of Allergy & Immunology, 2012, v. 159, n. 3, p. 263, doi. 10.1159/000338007
By:
- Knipping, Karen;
- van Esch, Betty C.A.M.;
- van Ieperen-van Dijk, Adrie G.;
- van Hoffen, Els;
- van Baalen, Ton;
- Knippels, Léon M.J.;
- van der Heide, Sicco;
- Dubois, Anthony E.J.;
- Garssen, Johan;
- Knol, Edward F.
Publication type:
Article
A Search for Biomarkers as Diagnostic Tools for Food Allergy: A Pilot Study in Peanut-Allergic Patients.
Published in:
International Archives of Allergy & Immunology, 2011, v. 155, n. 1, p. 23, doi. 10.1159/000318654
By:
- Peeters, Kim A. B. M.;
- Lamers, Robert-Jan A. N.;
- Penninks, André H.;
- Knol, Edward F.;
- Bruijnzeel-Koomen, Carla A. F. M.;
- van Nesselrooij, Joop H. J.;
- Knulst, André C.
Publication type:
Article
Neutrophil Transmigration across Monolayers of Endothelial Cells and Airway Epithelial Cells Is Regulated by Different Mechanismsa.
Published in:
Annals of the New York Academy of Sciences, 1996, v. 796, n. 1, p. 21, doi. 10.1111/j.1749-6632.1996.tb32563.x
By:
- LIU, LIXIN;
- MUL, FREDERIK P. J.;
- KUIJPERS, TACO W.;
- LUTTER, RENÉ;
- ROOS, DIRK;
- KNOL, EDWARD F.
Publication type:
Article
Systemic and local evidence for complement involvement in chronic spontaneous urticaria.
Published in:
Clinical & Translational Allergy, 2021, v. 11, n. 5, p. 1, doi. 10.1002/clt2.12011
By:
- Alizadeh Aghdam, Mehran;
- van den Elzen, Mignon;
- van Os‐Medendorp, Harmieke;
- van Dijk, Marijke R.;
- Knol, Edward F.;
- Knulst, André C.;
- Röckmann, Heike;
- Otten, Henny G.
Publication type:
Article
Retraction Note: Mast cells are the main interleukin 17-positive cells in anticitrullinated protein antibody-positive and -negative rheumatoid arthritis and osteoarthritis synovium.
Published in:
Arthritis Research & Therapy, 2015, v. 17, p. 1, doi. 10.1186/s13075-015-0847-3
By:
- Suurmond, Jolien;
- Dorjée, Annemarie L.;
- Boon, Mariëtte R.;
- Knol, Edward F.;
- Huizinga, Tom W. J.;
- Toes, René E. M.;
- Schuerwegh, Annemie J. M.
Publication type:
Article
Mast cells are the main interleukin 17-positive cells in anticitrullinated protein antibody-positive and -negative rheumatoid arthritis and osteoarthritis synovium.
Published in:
Arthritis Research & Therapy, 2011, v. 13, n. 5, p. 1, doi. 10.1186/ar3466
By:
- Suurmond, Jolien;
- Dorjée, Annemarie L.;
- Boon, Mariëtte R.;
- Knol, Edward F.;
- Huizinga, Tom W. J.;
- Toes, René E. M.;
- Schuerwegh, Annemie J. M.
Publication type:
Article
Aged mice display altered numbers and phenotype of basophils, and bone marrow-derived basophil activation, with a limited role for aging-associated microbiota.
Published in:
Immunity & Ageing, 2018, v. 15, n. 1, p. N.PAG, doi. 10.1186/s12979-018-0135-6
By:
- van Beek, Adriaan A.;
- Fransen, Floris;
- Meijer, Ben;
- de Vos, Paul;
- Knol, Edward F.;
- Savelkoul, Huub F. J.
Publication type:
Article
Requirements for effective IgE cross-linking on mast cells and basophils.
Published in:
Molecular Nutrition & Food Research, 2006, v. 50, n. 7, p. 620, doi. 10.1002/mnfr.200500272
By:
- Knol, Edward F.
Publication type:
Article
CD8+ T Cells in the Lesional Skin of Atopic Dermatitis and Psoriasis Patients Are an Important Source of IFN-γ, IL-13, IL-17, and IL-22.
Published in:
Journal of Investigative Dermatology, 2013, v. 133, n. 4, p. 973, doi. 10.1038/jid.2012.456
By:
- Hijnen, DirkJan;
- Knol, Edward F;
- Gent, Yoony Y;
- Giovannone, Barbara;
- J P Beijn, Scott;
- Kupper, Thomas S;
- Bruijnzeel-Koomen, Carla A F M;
- Clark, Rachael A
Publication type:
Article
Modulation of Lymphocyte Function In Vivo via Inhibition of Calcineurin or Purine Synthesis in Patients with Atopic Dermatitis.
Published in:
Journal of Investigative Dermatology, 2012, v. 132, n. 10, p. 2476, doi. 10.1038/jid.2012.150
By:
- Knol, Edward F;
- Haeck, Inge M;
- van Kraats, Annemieke A;
- Laaper-Ertmann, Marloes;
- Giovannone, Barbara;
- Hijnen, DirkJan;
- Nijhuis, Evert;
- de Bruin-Weller, Marjolein S;
- Knol, Mirjam J;
- Bruijnzeel-Koomen, Carla A
Publication type:
Article
Decreased Neutrophil Skin Infiltration After UVB Exposure in Patients with Polymorphous Light Eruption.
Published in:
Journal of Investigative Dermatology, 2004, v. 123, n. 1, p. 202, doi. 10.1111/j.0022-202X.2004.22734.x
By:
- Schornagel, Ines J.;
- Sigurdsson, Vigfús;
- Nijhuis, Evert H. J.;
- Bruijnzeel-Koomen, Carla A. F. M.;
- Knol, Edward F.
Publication type:
Article
Epidermal Langerhans Cell Depletion After Artificial Ultraviolet B Irradiation of Human Skin In Vivo: Apoptosis Versus Migration.
Published in:
Journal of Investigative Dermatology, 2002, v. 118, n. 5, p. 812, doi. 10.1046/j.1523-1747.2002.01742.x
By:
- Kölgen, Wendy;
- Both, Hilde;
- van Weelden, Huib;
- Guikers, Kees L. H;
- Bruijnzeel-Koomen, Carla A. F. M;
- Knol, Edward F;
- van Vloten, Willem A;
- de Gruijl, Frank R
Publication type:
Article
CD11b+ Cells and Ultraviolet-B-Resistant CD1a+ Cells in Skin of Patients with Polymorphous Light Eruption.
Published in:
Journal of Investigative Dermatology, 1999, v. 113, n. 1, p. 4, doi. 10.1046/j.1523-1747.1999.00625.x
By:
- Kölgen, Wendy;
- Van Weelden, Huib;
- Den Hengst, Sarah;
- Guikers, Kees L. H.;
- Kiekens, Rebecca C. M.;
- Knol, Edward F.;
- Bruijnzeel-Koomen, Carla A. F. M.;
- van Vloten, Willem A.;
- de Gruijl, Frank R.
Publication type:
Article
Differential dynamics of TARC during JAK‐inhibitor therapy compared to biological therapies targeting type 2 inflammation.
Published in:
Clinical & Experimental Allergy, 2024, v. 54, n. 4, p. 294, doi. 10.1111/cea.14442
By:
- Boesjes, Celeste M.;
- Bakker, Daphne S.;
- Knol, Edward F.;
- de Graaf, Marlies;
- van Wijk, Femke;
- de Bruin‐Weller, Marjolein S.
Publication type:
Article
Response of FcεRI‐bearing leucocytes to omalizumab in chronic spontaneous urticaria.
Published in:
Clinical & Experimental Allergy, 2020, v. 50, n. 3, p. 364, doi. 10.1111/cea.13566
By:
- Alizadeh Aghdam, Mehran;
- Knol, Edward F.;
- den Elzen, Mignon;
- Hartog Jager, Constance;
- Os‐Medendorp, Harmieke;
- Knulst, André C.;
- Otten, Henny G.;
- Röckmann, Heike
Publication type:
Article
Early identification of atopic dermatitis patients in need of systemic immunosuppressive treatment.
Published in:
Clinical & Experimental Allergy, 2019, v. 49, n. 12, p. 1641, doi. 10.1111/cea.13495
By:
- Bakker, Daphne S.;
- Drylewicz, Julia;
- Nierkens, Stefan;
- Knol, Edward F.;
- Giovannone, Barbara;
- Delemarre, Eveline M.;
- Schaft, Jorien;
- Balak, Deepak M. W.;
- Bruin‐Weller, Marjolein S.;
- Thijs, Judith L.
Publication type:
Article
Measurement of IgE to hazelnut allergen components cannot replace hazelnut challenge in Dutch adults.
Published in:
Allergy, 2022, v. 77, n. 5, p. 1559, doi. 10.1111/all.15166
By:
- Lyons, Sarah A.;
- Welsing, Paco M. J.;
- Hakobyan, Mariam;
- Kansen, Hannah M.;
- Knol, Edward F.;
- Otten, Henny G.;
- van Ree, Ronald;
- Knulst, André C.;
- Le, Thuy‐My
Publication type:
Article
COVID‐19 pandemic and allergen immunotherapy—an EAACI survey.
Published in:
Allergy, 2021, v. 76, n. 11, p. 3504, doi. 10.1111/all.14793
By:
- Pfaar, Oliver;
- Agache, Ioana;
- Bonini, Matteo;
- Brough, Helen Annaruth;
- Chivato, Tomás;
- Del Giacco, Stefano R.;
- Gawlik, Radoslaw;
- Gelincik, Aslı;
- Hoffmann‐Sommergruber, Karin;
- Jutel, Marek;
- Klimek, Ludger;
- Knol, Edward F.;
- Lauerma, Antti;
- Ollert, Markus;
- O'Mahony, Liam;
- Mortz, Charlotte G.;
- Palomares, Oscar;
- Riggioni, Carmen;
- Schwarze, Jürgen;
- Skypala, Isabel
Publication type:
Article
Immune modulation via T regulatory cell enhancement: Disease‐modifying therapies for autoimmunity and their potential for chronic allergic and inflammatory diseases—An EAACI position paper of the Task Force on Immunopharmacology (TIPCO).
Published in:
Allergy, 2021, v. 76, n. 1, p. 90, doi. 10.1111/all.14478
By:
- Roth‐Walter, Franziska;
- Adcock, Ian M.;
- Benito‐Villalvilla, Cristina;
- Bianchini, Rodolfo;
- Bjermer, Leif;
- Boyman, Onur;
- Caramori, Gaetano;
- Cari, Luigi;
- Fan Chung, Kian;
- Diamant, Zuzana;
- Eguiluz‐Gracia, Ibon;
- Knol, Edward F.;
- Kolios, Antonios;
- Levi‐Schaffer, Francesca;
- Nocentini, Giuseppe;
- Palomares, Oscar;
- Redegeld, Frank;
- Van Esch, Betty;
- Stellato, Cristiana
Publication type:
Article
Immunology of COVID‐19: Mechanisms, clinical outcome, diagnostics, and perspectives—A report of the European Academy of Allergy and Clinical Immunology (EAACI).
Published in:
Allergy, 2020, v. 75, n. 10, p. 2445, doi. 10.1111/all.14462
By:
- Sokolowska, Milena;
- Lukasik, Zuzanna M.;
- Agache, Ioana;
- Akdis, Cezmi A.;
- Akdis, Deniz;
- Akdis, Mübeccel;
- Barcik, Weronika;
- Brough, Helen A.;
- Eiwegger, Thomas;
- Eljaszewicz, Andrzej;
- Eyerich, Stefanie;
- Feleszko, Wojciech;
- Gomez‐Casado, Cristina;
- Hoffmann‐Sommergruber, Karin;
- Janda, Jozef;
- Jiménez‐Saiz, Rodrigo;
- Jutel, Marek;
- Knol, Edward F.;
- Kortekaas Krohn, Inge;
- Kothari, Akash
Publication type:
Article
Dupilumab is very effective in a large cohort of difficult‐to‐treat adult atopic dermatitis patients: First clinical and biomarker results from the BioDay registry.
Published in:
Allergy, 2020, v. 75, n. 1, p. 116, doi. 10.1111/all.14080
By:
- Ariëns, Lieneke F. M.;
- Schaft, Jorien;
- Bakker, Daphne S.;
- Balak, Deepak;
- Romeijn, Margreet L. E.;
- Kouwenhoven, Tessa;
- Kamsteeg, Marijke;
- Giovannone, Barbara;
- Drylewicz, Julia;
- Amerongen, Cynthia Catalina Aurora;
- Delemarre, Evelien M.;
- Knol, Edward F.;
- Wijk, Femke;
- Nierkens, Stefan;
- Thijs, Judith L.;
- Schuttelaar, Marie L. A.;
- Bruin‐Weller, Marjolein S.
Publication type:
Article
Biomarkers and clinical characteristics of autoimmune chronic spontaneous urticaria: Results of the PURIST Study.
Published in:
Allergy, 2019, v. 74, n. 12, p. 2427, doi. 10.1111/all.13949
By:
- Schoepke, Nicole;
- Asero, Riccardo;
- Ellrich, André;
- Ferrer, Marta;
- Gimenez‐Arnau, Ana;
- E. H. Grattan, Clive;
- Jakob, Thilo;
- Konstantinou, George N.;
- Raap, Ulrike;
- Skov, Per Stahl;
- Staubach, Petra;
- Kromminga, Arno;
- Zhang, Ke;
- Bindslev‐Jensen, Carsten;
- Daschner, Alvaro;
- Kinaciyan, Tamar;
- Knol, Edward F.;
- Makris, Michael;
- Marrouche, Nadine;
- Schmid‐Grendelmeier, Peter
Publication type:
Article
Biomarkers detected in dried blood spots from atopic dermatitis patients strongly correlate with disease severity.
Published in:
Allergy, 2019, v. 74, n. 11, p. 2240, doi. 10.1111/all.13839
By:
- Thijs, Judith L.;
- Fiechter, Renée;
- Giovannone, Barbara;
- de Bruin‐Weller, Marjolein S.;
- Knol, Edward F.;
- Bruijnzeel‐Koomen, Carla A. F. M.;
- Drylewicz, Julia;
- Nierkens, Stefan;
- Hijnen, DirkJan
Publication type:
Article
EASI p‐EASI: Predicting disease severity in atopic dermatitis patients treated with cyclosporin A.
Published in:
Allergy, 2019, v. 74, n. 3, p. 613, doi. 10.1111/all.13651
By:
- Thijs, Judith L.;
- Drylewicz, Julia;
- Bruijnzeel‐Koomen, Carla A. F. M.;
- Giovannone, Barbara;
- Knol, Edward F.;
- de Bruin‐Weller, Marjolein S.;
- Nierkens, Stefan;
- Hijnen, DirkJan
Publication type:
Article
Legends of Allergy/Immunology: Carla Bruijnzeel‐Koomen.
Published in:
Allergy, 2019, v. 74, n. 3, p. 637, doi. 10.1111/all.13627
By:
- Fieten, Karin B.;
- Knol, Edward F.
Publication type:
Article
Comparing biologicals and small molecule drug therapies for chronic respiratory diseases: An EAACI Taskforce on Immunopharmacology position paper.
Published in:
Allergy, 2019, v. 74, n. 3, p. 432, doi. 10.1111/all.13642
By:
- Roth‐Walter, Franziska;
- Adcock, Ian M.;
- Benito‐Villalvilla, Cristina;
- Bianchini, Rodolfo;
- Bjermer, Leif;
- Caramori, Gaetano;
- Cari, Luigi;
- Chung, Kian Fan;
- Diamant, Zuzana;
- Eguiluz‐Gracia, Ibon;
- Knol, Edward F.;
- Kolios, Antonios G. A.;
- Levi‐Schaffer, Francesca;
- Nocentini, Giuseppe;
- Palomares, Oscar;
- Puzzovio, Pier Giorgio;
- Redegeld, Frank A.;
- van Esch, Betty C. A. M.;
- Stellato, Cristiana
Publication type:
Article
Basophils and antigen presentation: of mice and not men?
Published in:
Allergy, 2012, v. 67, n. 5, p. 579, doi. 10.1111/j.1398-9995.2012.02816.x
By:
- Knol, Edward F.;
- Gibbs, Bernhard F.
Publication type:
Article
Diagnostic Tests Based on Human Basophils: Potentials, Pitfalls and Perspectives.
Published in:
International Archives of Allergy & Immunology, 2006, v. 141, n. 1, p. 79, doi. 10.1159/000094495
By:
- Kleine-Tebbe, Jörg;
- Erdmann, Stephan;
- Knol, Edward F.;
- MacGlashan, Jr., Donald W.;
- Poulsen, Lars K.;
- Gibbs, Bernhard F.
Publication type:
Article
Eosinophil Granulocyte Interaction with Serum-Opsonized Particles:& ;Binding and Degranulation Are Enhanced by Tumor Necrosis Factor Alpha.
Published in:
International Archives of Allergy & Immunology, 1998, v. 115, n. 2, p. 121, doi. 10.1159/000023891
By:
- Egesten, Arne;
- Blom, Michaela;
- Calafat, Jero;
- Janssen, Hans;
- Knol, Edward F.
Publication type:
Article
Localization of Granule Proteins in Human Eosinophil Bone Marrow Progenitors.
Published in:
International Archives of Allergy & Immunology, 1997, v. 114, n. 2, p. 130, doi. 10.1159/000237657
By:
- Egesten, Arne;
- Calafat, Jero;
- Weller, Peter F.;
- Knol, Edward F.;
- Janssen, Hans;
- Walz, Thomas M.;
- Olsson, Inge
Publication type:
Article
Variability of IgE-Dependent Histamine-Releasing Activity in Supernatants of Human Mononuclear Cells.
Published in:
International Archives of Allergy & Immunology, 1994, v. 103, n. 1, p. 44, doi. 10.1159/000236604
By:
- Pasmans, Suzanne G.M.A.;
- Witteman, Agnes M.;
- Aalbers, Marja;
- Boonstra, Joke G.;
- Mul, Erik P.J.;
- van der Zee, Jaring S.;
- Knol, Edward F.;
- Jansen, Henk M.;
- Aalberse, Rob C.
Publication type:
Article
Sensitization to PR-10 proteins is indicative of distinctive sensitization patterns in adults with a suspected food allergy.
Published in:
Clinical & Translational Allergy, 2017, v. 7, p. 1, doi. 10.1186/s13601-017-0177-4
By:
- Blankestijn, Mark A.;
- Knulst, André C.;
- Knol, Edward F.;
- Le, Thuy-My;
- Rockmann, Heike;
- Otten, Henny G.;
- Klemans, Rob J. B.
Publication type:
Article
Application of the adverse outcome pathway (AOP) concept to structure the available in vivo and in vitro mechanistic data for allergic sensitization to food proteins.
Published in:
Clinical & Translational Allergy, 2017, v. 7, p. 1, doi. 10.1186/s13601-017-0152-0
By:
- van Bilsen, Jolanda H. M.;
- Sienkiewicz-Szłapka, Edyta;
- Lozano-Ojalvo, Daniel;
- Willemsen, Linette E. M.;
- Antunes, Celia M.;
- Molina, Elena;
- Smit, Joost J.;
- Wróblewska, Barbara;
- Wichers, Harry J.;
- Knol, Edward F.;
- Ladics, Gregory S.;
- Pieters, Raymond H. H.;
- Denery-Papini, Sandra;
- Vissers, Yvonne M.;
- Bavaro, Simona L.;
- Larré, Colette;
- Verhoeckx, Kitty C. M.;
- Roggen, Erwin L.
Publication type:
Article
The bactericidal/permeability-increasing protein (BPI) is membrane-associated in azurophil granules of human neutrophils, and relocation occurs upon cellular activation.
Published in:
APMIS, 2000, v. 108, n. 3, p. 201, doi. 10.1034/j.1600-0463.2000.d01-45.x
By:
- Calafat, Jero;
- Janssen, Hans;
- Knol, Edward F.;
- Malm, Johan;
- Egesten, Arne
Publication type:
Article
Efficient sorting of TNF-alpha to rodent mast cell granules is dependent on N-linked glycosylation.
Published in:
European Journal of Immunology, 2006, v. 36, n. 4, p. 997, doi. 10.1002/eji.200535323
By:
- Olszewski, Maciej B.;
- Trzaska, Dominika;
- Knol, Edward F.;
- Adamczewska, Violetta;
- Dastych, Jaroslaw
Publication type:
Article
Differential activation of human basophils by anti-IgE and formyl-methionyl-leucylphenylalanine. Indications for protein kinase C-dependent and -independent activation pathways.
Published in:
European Journal of Immunology, 1991, v. 21, n. 4, p. 881, doi. 10.1002/eji.1830210404
By:
- Knol, Edward F.;
- Koenderman, Leo;
- Mul, Frederik P. J.;
- Verhoeven, Arthur J.;
- Roos, Dirk
Publication type:
Article
Management of Cow's Milk Allergy from an Immunological Perspective: What Are the Options?
Published in:
Nutrients, 2019, v. 11, n. 11, p. 2734, doi. 10.3390/nu11112734
By:
- Knol, Edward F.;
- de Jong, Nicolette W.;
- Ulfman, Laurien H.;
- Tiemessen, Machteld M.
Publication type:
Article

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