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Proteome-Wide Discovery of Cortical Proteins That May Provide Motor Resilience to Offset the Negative Effects of Pathologies in Older Adults.
- Published in:
- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2023, v. 78, n. 3, p. 494, doi. 10.1093/gerona/glac105
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- Article
How do we measure the epigenome(s)?
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- Multiple Sclerosis Journal, 2018, v. 24, n. 4, p. 446, doi. 10.1177/1352458517750772
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- Publication type:
- Article
Cell-type-specific Alzheimer’s disease polygenic risk scores are associated with distinct disease processes in Alzheimer’s disease.
- Published in:
- Nature Communications, 2023, p. 1, doi. 10.1038/s41467-023-43132-2
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- Publication type:
- Article
Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer's disease.
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- Nature Communications, 2017, v. 8, n. 4, p. 14931, doi. 10.1038/ncomms14931
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- Publication type:
- Article
Comparative study of unsupervised dimension reduction techniques for the visualization of microarray gene expression data.
- Published in:
- BMC Bioinformatics, 2010, v. 11, p. 567, doi. 10.1186/1471-2105-11-567
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- Publication type:
- Article
The epigenome in Alzheimer's disease: current state and approaches for a new path to gene discovery and understanding disease mechanism.
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- Acta Neuropathologica, 2016, v. 132, n. 4, p. 503, doi. 10.1007/s00401-016-1612-7
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- Publication type:
- Article
Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data.
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- 2017
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- Publication type:
- journal article
An evaluation of methods to test predefined genomic regions for differential methylation in bisulfite sequencing data.
- Published in:
- Briefings in Bioinformatics, 2016, v. 17, n. 5, p. 796, doi. 10.1093/bib/bbv095
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- Publication type:
- Article
Cancer gene prioritization by integrative analysis of mRNA expression and DNA copy number data: a comparative review.
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- Briefings in Bioinformatics, 2013, v. 14, n. 1, p. 27, doi. 10.1093/bib/bbs005
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- Publication type:
- Article
EZH2 mutations and their association with PICALM-MLLT10 positive acute leukaemia.
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- British Journal of Haematology, 2012, v. 157, n. 3, p. 387, doi. 10.1111/j.1365-2141.2011.08986.x
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- Publication type:
- Article
Epigenomic features related to microglia are associated with attenuated effect of APOE ε4 on Alzheimer's disease risk in humans: Human neuropathology: AD neuropathology.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043533
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- Publication type:
- Article
P3‐136: MODULE QUANTITATIVE TRAIT LOCI ANALYSIS IMPLICATES TMEM106B AND RBFOX1 AS KEY BRAIN TRANSCRIPTOME REGULATORS IN OLDER ADULTS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1120, doi. 10.1016/j.jalz.2018.06.1493
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- Publication type:
- Article
demuxmix: demultiplexing oligonucleotide-barcoded single-cell RNA sequencing data with regression mixture models.
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- Bioinformatics, 2023, v. 39, n. 8, p. 1, doi. 10.1093/bioinformatics/btad481
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- Publication type:
- Article
Leukemia Gene Atlas - A Public Platform for Integrative Exploration of Genome-Wide Molecular Data.
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- PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0039148
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- Publication type:
- Article
Proximal and distal effects of genetic susceptibility to multiple sclerosis on the T cell epigenome.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-27427-w
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- Publication type:
- Article
Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-27204-9
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- Publication type:
- Article
ZCCHC17 Modulates Neuronal RNA Splicing and Supports Cognitive Resilience in Alzheimer's Disease.
- Published in:
- Journal of Neuroscience, 2024, v. 44, n. 3, p. 1, doi. 10.1523/JNEUROSCI.2324-22.2023
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- Publication type:
- Article
Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate over time in fibroblasts.
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- PLoS Biology, 2024, v. 22, n. 8, p. 1, doi. 10.1371/journal.pbio.3002723
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- Publication type:
- Article
Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.
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- JAMA Neurology, 2021, v. 78, n. 1, p. 102, doi. 10.1001/jamaneurol.2020.3536
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- Publication type:
- Article
Cortical proteins may provide motor resilience in older adults.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-90859-3
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- Publication type:
- Article
Characterization of mitochondrial DNA quantity and quality in the human aged and Alzheimer's disease brain.
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- Molecular Neurodegeneration, 2021, v. 16, n. 1, p. 1, doi. 10.1186/s13024-021-00495-8
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- Publication type:
- Article
BIN1 protein isoforms are differentially expressed in astrocytes, neurons, and microglia: neuronal and astrocyte BIN1 are implicated in tau pathology.
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- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00387-3
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- Publication type:
- Article
Considerations for integrative multi‐omic approaches to explore Alzheimer's disease mechanisms.
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- Brain Pathology, 2020, v. 30, n. 5, p. 984, doi. 10.1111/bpa.12878
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- Publication type:
- Article
Integrative analysis of multiple genomic variables using a hierarchical Bayesian model.
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- Bioinformatics, 2017, v. 33, n. 20, p. 3220, doi. 10.1093/bioinformatics/btx356
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- Publication type:
- Article
Integrative analysis of histone ChIP-seq and transcription data using Bayesian mixture models.
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- Bioinformatics, 2014, v. 30, n. 8, p. 1154, doi. 10.1093/bioinformatics/btu003
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- Publication type:
- Article
Detection of significantly differentially methylated regions in targeted bisulfite sequencing data.
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- Bioinformatics, 2013, v. 29, n. 13, p. 1647, doi. 10.1093/bioinformatics/btt263
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- Publication type:
- Article
R453Plus1Toolbox: an R/Bioconductor package for analyzing Roche 454 Sequencing data.
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- Bioinformatics, 2011, v. 27, n. 8, p. 1162, doi. 10.1093/bioinformatics/btr102
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- Publication type:
- Article
Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia.
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- Nature Medicine, 2012, v. 18, n. 4, p. 605, doi. 10.1038/nm.2661
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- Publication type:
- Article
A New Workflow for Whole-Genome Sequencing of Single Human Cells.
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- Human Mutation, 2014, v. 35, n. 10, p. 1260, doi. 10.1002/humu.22625
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- Publication type:
- Article
Rheumatoid arthritis-associated RBPJ polymorphism alters memory CD4<sup>+</sup> T cells.
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- Human Molecular Genetics, 2016, v. 25, n. 2, p. 404, doi. 10.1093/hmg/ddv474
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- Publication type:
- Article
A cortical immune network map identifies distinct microglial transcriptional programs associated with β-amyloid and Tau pathologies.
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- Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-020-01175-9
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- Publication type:
- Article
Epigenetic dysregulation of K<sub>Ca</sub>3.1 channels induces poor prognosis in lung cancer.
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- International Journal of Cancer, 2015, v. 137, n. 6, p. 1306, doi. 10.1002/ijc.29490
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- Publication type:
- Article
Association of short tandem repeats with neuropathological features in late‐onset of Alzheimer's disease brains.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.066552
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- Publication type:
- Article
Microglia‐specific Alzheimer's disease polygenic risk score is associated with amyloid‐β, tau, and microglial activation.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.061819
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- Publication type:
- Article
Integration of GWAS and brain transcriptomic analyses in a multiethnic sample of 35,245 older adults identifies DCDC2 gene as predictor of episodic memory maintenance.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1797, doi. 10.1002/alz.12524
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- Publication type:
- Article
Epigenomic features related to microglia are associated with attenuated effect of APOE ε4 on Alzheimer's disease risk in humans.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 688, doi. 10.1002/alz.12425
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- Publication type:
- Article
Multi‐region brain transcriptomes uncover two subtypes of aging individuals with differences in the impact of APOEe4.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.057240
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- Publication type:
- Article
Cell type‐specific Alzheimer's disease polygenic risk scores are associated with distinct disease processes in preclinical Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.055304
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- Publication type:
- Article
Bayesian integrative analysis of epigenomic and transcriptomic data identifies Alzheimer's disease candidate genes and networks.
- Published in:
- PLoS Computational Biology, 2020, v. 16, n. 4, p. 1, doi. 10.1371/journal.pcbi.1007771
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- Publication type:
- Article