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Is Parkinson's disease a lysosomal disorder?
- Published in:
- 2018
- By:
- Publication type:
- journal article
The Novel Trk Receptor Tyrosine Kinase Inhibitor CEP-701 (KT-5555) Exhibits Antitumor Efficacy against Human Pancreatic Carcinoma (Panc1) Xenograft Growth and In Vivo Invasiveness.
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- Annals of the New York Academy of Sciences, 1999, v. 880, n. 1, p. 252, doi. 10.1111/j.1749-6632.1999.tb09530.x
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- Publication type:
- Article
Modulation of angiogenesis by human gliomaxenograft models that differentially express vascular endothelial growth factor.
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- Clinical & Experimental Metastasis, 1998, v. 16, n. 6, p. 559, doi. 10.1023/A:1006598419541
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- Publication type:
- Article
Proteomic Analysis of Niemann-Pick Type C Hepatocytes Reveals Potential Therapeutic Targets for Liver Damage.
- Published in:
- Cells (2073-4409), 2021, v. 10, n. 8, p. 2159, doi. 10.3390/cells10082159
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- Publication type:
- Article
Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomas.
- Published in:
- Oncogene, 2002, v. 21, n. 20, p. 3190, doi. 10.1038/sj.onc.1205428
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- Publication type:
- Article
Combination therapy with 2-difluoromethylornithine and a polyamine transport inhibitor against murine squamous cell carcinoma.
- Published in:
- International Journal of Cancer, 2006, v. 118, n. 9, p. 2344, doi. 10.1002/ijc.21621
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- Publication type:
- Article
Stromelysin-1/matrix metalloproteinase-3 (MMP-3) expression accounts for invasive properties of human astrocytoma cell lines.
- Published in:
- International Journal of Cancer, 2003, v. 106, n. 5, p. 676, doi. 10.1002/ijc.11286
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- Publication type:
- Article
Neurotrophins and Trk receptors in human pancreatic ductal adenocarcinoma: Expression patterns and effects on In vitro invasive behavior.
- Published in:
- International Journal of Cancer, 1999, v. 81, n. 3, p. 417, doi. 10.1002/(SICI)1097-0215(19990505)81:3<417::AID-IJC16>3.0.CO;2-6
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- Publication type:
- Article
Identification of inbred mouse strains harboring genetic modifiers of mammary tumor age of onset and metastatic progression.
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- International Journal of Cancer, 1998, v. 77, n. 4, p. 640, doi. 10.1002/(SICI)1097-0215(19980812)77:4<640::AID-IJC26>3.0.CO;2-8
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- Publication type:
- Article
Glucocerebrosidase mutations disrupt the lysosome and now the mitochondria.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-42107-7
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- Publication type:
- Article
Anatomically Defined Neuron-Based Rescue of Neurodegenerative Niemann-Pick Type C Disorder.
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- Journal of Neuroscience, 2011, v. 31, n. 12, p. 4367, doi. 10.1523/JNEUROSCI.5981-10.2011
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- Publication type:
- Article
Exposure to Eosinophilic Esophagitis Limits Esophageal Carcinogenesis in a Murine Model.
- Published in:
- FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R5429
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- Publication type:
- Article
Hypoxia induces IGFBP3 in esophageal squamous cancer cells through HIF-1α-mediated mRNA transcription and continuous protein synthesis.
- Published in:
- FASEB Journal, 2012, v. 26, n. 6, p. 2620, doi. 10.1096/fj.11-198598
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- Publication type:
- Article
Mouse models of cystathionine β-synthase deficiency reveal significant threshold effects of hyperhomocysteinemia.
- Published in:
- FASEB Journal, 2009, v. 23, n. 3, p. 883, doi. 10.1096/fj.08-120584
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- Publication type:
- Article
Imatinib therapy blocks cerebellar apoptosis and improves neurological symptoms in a mouse model of Niemann-Pick type C disease.
- Published in:
- FASEB Journal, 2008, v. 22, n. 10, p. 3617, doi. 10.1096/fj.07-102715
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- Publication type:
- Article
Complement is dispensable for neurodegeneration in Niemann-Pick disease type C.
- Published in:
- Journal of Neuroinflammation, 2012, v. 9, n. 1, p. 216, doi. 10.1186/1742-2094-9-216
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- Publication type:
- Article
Therapy of murine squamous cell carcinomas with 2-difluoromethylornithine.
- Published in:
- Journal of Carcinogenesis, 2004, v. 3, n. 1, p. 10, doi. 10.1186/1477-3163-3-10
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- Publication type:
- Article
Insulin-like growth factor-binding protein-3 promotes transforming growth factor-β1-mediated epithelial-to-mesenchymal transition and motility in transformed human esophageal cells.
- Published in:
- Carcinogenesis, 2010, v. 31, n. 8, p. 1344, doi. 10.1093/carcin/bgq108
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- Publication type:
- Article
Hypoxia activates the cyclooxygenase-2–prostaglandin E synthase axis.
- Published in:
- Carcinogenesis, 2010, v. 31, n. 3, p. 427, doi. 10.1093/carcin/bgp326
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- Publication type:
- Article
Malignant conversion of non-tumorigenic murine skin keratinocytes overexpressing PACE4.
- Published in:
- Carcinogenesis, 2002, v. 23, n. 4, p. 565, doi. 10.1093/carcin/23.4.565
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- Publication type:
- Article
Neuronal and epithelial cell rescue resolves chronic systemic inflammation in the lipid storage disorder Niemann-Pick C.
- Published in:
- Human Molecular Genetics, 2012, v. 21, n. 13, p. 2946, doi. 10.1093/hmg/dds126
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- Publication type:
- Article
Expression of mutant human cystathionine β-synthase rescues neonatal lethality but not homocystinuria in a mouse model.
- Published in:
- Human Molecular Genetics, 2005, v. 14, n. 15, p. 2201, doi. 10.1093/hmg/ddi224
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- Publication type:
- Article
Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma.
- Published in:
- Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01500-9
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- Publication type:
- Article
Development of a syngeneic mouse model of epithelial ovarian cancer.
- Published in:
- Journal of Ovarian Research, 2010, v. 3, n. 1, p. 1, doi. 10.1186/1757-2215-3-24
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- Publication type:
- Article
The lysosomal β-glucocerebrosidase strikes mitochondria: implications for Parkinson's therapeutics.
- Published in:
- Brain: A Journal of Neurology, 2024, v. 147, n. 8, p. 2610, doi. 10.1093/brain/awae070
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- Publication type:
- Article
Formaldehyde-Induced Lesions of Xenotransplanted Human Nasal Respiratory Epithelium.
- Published in:
- Toxicologic Pathology, 1989, v. 17_1, n. PT1, p. 33, doi. 10.1177/019262338901700105
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- Publication type:
- Article
Pathological Changes Induced by Formaldehyde in Open-Ended Rat Tracheal Implants Preexposed to Benzo(a)pyrene.
- Published in:
- Toxicologic Pathology, 1987, v. 15, n. 4, p. 401, doi. 10.1177/019262338701500403
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- Publication type:
- Article
A Mouse Systems Genetics Approach Reveals Common and Uncommon Genetic Modifiers of Hepatic Lysosomal Enzyme Activities and Glycosphingolipids.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 5, p. 4915, doi. 10.3390/ijms24054915
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- Publication type:
- Article
Genetic Background Matters: Population-Based Studies in Model Organisms for Translational Research.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 14, p. 7570, doi. 10.3390/ijms23147570
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- Publication type:
- Article
Complement Component C3 Participates in Early Stages of Niemann–Pick C Mouse Liver Damage.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 6, p. 2127, doi. 10.3390/ijms21062127
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- Publication type:
- Article
Gadolinium Chloride Rescues Niemann–Pick Type C Liver Damage.
- Published in:
- International Journal of Molecular Sciences, 2018, v. 19, n. 11, p. 3599, doi. 10.3390/ijms19113599
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- Publication type:
- Article
Resistance to Serum-induced Terminal Differentiation in Normal Human Tracheobronchial Epithelial Cells after in vivo Exposure to 7,12-Dimethylbenz[a]anthracene.
- Published in:
- Cancer Science, 1988, v. 79, n. 6, p. 734, doi. 10.1111/j.1349-7006.1988.tb02230.x
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- Publication type:
- Article
Transgenic mice overexpressing the wild-type form of the HMGA1 gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas.
- Published in:
- Oncogene, 2005, v. 24, n. 21, p. 3427, doi. 10.1038/sj.onc.1208501
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- Publication type:
- Article
Visinin-like protein-1 is a potent inhibitor of cell adhesion and migration in squamous carcinoma cells.
- Published in:
- Oncogene, 2005, v. 24, n. 14, p. 2307, doi. 10.1038/sj.onc.1208476
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- Publication type:
- Article
AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth.
- Published in:
- Oncogene, 2004, v. 23, n. 34, p. 5853, doi. 10.1038/sj.onc.1207721
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- Publication type:
- Article
Secretion of gelatinases and tissue inhibitors of metalloproteinases by human lung cancer cell lines and revertant cell lines: Not an invariant correlation with metastasis.
- Published in:
- International Journal of Cancer, 1992, v. 52, n. 3, p. 366, doi. 10.1002/ijc.2910520307
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- Publication type:
- Article
Propafenone Versus Vernakalant for Conversion of Recent-Onset Atrial Fibrillation.
- Published in:
- Cardiovascular Therapeutics, 2013, v. 31, n. 6, p. 377, doi. 10.1111/1755-5922.12036
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- Publication type:
- Article
Lack of Activation of the Unfolded Protein Response in Mouse and Cellular Models of Niemann-Pick Type C Disease.
- Published in:
- Neurodegenerative Diseases, 2011, v. 8, n. 3, p. 124, doi. 10.1159/000316540
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- Publication type:
- Article
Study of FoxA Pioneer Factor at Silent Genes Reveals Rfx- Repressed Enhancer at Cdx2 and a Potential Indicator of Esophageal Adenocarcinoma Development.
- Published in:
- PLoS Genetics, 2011, v. 7, n. 9, p. 1, doi. 10.1371/journal.pgen.1002277
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- Publication type:
- Article
Direct Correlation between Proliferative Activity and Dysplasia in Pancreatic Intraepithelial Neoplasia (PanIN): Additional Evidence for a Recently Proposed Model of Progression.
- Published in:
- Modern Pathology, 2002, v. 15, n. 4, p. 441, doi. 10.1038/modpathol.3880544
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- Publication type:
- Article
Correction to: Outcomes of a comprehensive strategy during repeat atrial fibrillation ablation.
- Published in:
- 2022
- By:
- Publication type:
- Correction Notice
Outcomes of a comprehensive strategy during repeat atrial fibrillation ablation.
- Published in:
- Journal of Interventional Cardiac Electrophysiology, 2022, v. 65, n. 2, p. 391, doi. 10.1007/s10840-022-01190-4
- By:
- Publication type:
- Article
Visinin-like proteins (VSNLs): interaction partners and emerging functions in signal transduction of a subfamily of neuronal Ca<sup>2+</sup>-sensor proteins.
- Published in:
- 2009
- By:
- Publication type:
- Correction notice
Correction to: Buthionine sulfoximine sensitizes antihormone-resistant human breast cancer cells to estrogen-induced apoptosis.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Targeting proprotein convertases in furin-rich lung cancer cells results in decreased in vitro and in vivo growth.
- Published in:
- Molecular Carcinogenesis, 2017, v. 56, n. 3, p. 1182, doi. 10.1002/mc.22550
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- Publication type:
- Article
Enhanced aggressiveness of benzopyrene-induced squamous carcinomas in transgenic mice overexpressing the proprotein convertase PACE4 (PCSK6).
- Published in:
- Molecular Carcinogenesis, 2015, v. 54, n. 10, p. 1122, doi. 10.1002/mc.22183
- By:
- Publication type:
- Article
Regulation of HIF-1 alpha by the proprotein convertases furin and PC7 in human squamous carcinoma cells.
- Published in:
- Molecular Carcinogenesis, 2015, v. 54, n. 9, p. 698, doi. 10.1002/mc.22131
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- Publication type:
- Article
Frequent activation of AKT2 kinase in human pancreatic carcinomas.
- Published in:
- Journal of Cellular Biochemistry, 2002, v. 87, n. 4, p. 470, doi. 10.1002/jcb.10287
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- Publication type:
- Article
Invasive and Metastatic Potential of a v-Ha-ras-Transformed Human Bronchial Epithelial Cell Line.
- Published in:
- JNCI: Journal of the National Cancer Institute, 1989, v. 81, n. 8, p. 587
- By:
- Publication type:
- Article
Dll1+ quiescent tumor stem cells drive chemoresistance in breast cancer through NF-κB survival pathway.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20664-5
- By:
- Publication type:
- Article