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Overexpression of wild-type human amyloid precursor protein alters GABAergic transmission.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-97144-3
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- Article
A Role for GDNF and Soluble APP as Biomarkers of Amyotrophic Lateral Sclerosis Pathophysiology.
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- Frontiers in Neurology, 2018, p. 1, doi. 10.3389/fneur.2018.00384
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- Article
Amyloid precursor protein controls cholesterol turnover needed for neuronal activity.
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- EMBO Molecular Medicine, 2013, v. 5, n. 4, p. 608, doi. 10.1002/emmm.201202215
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- Article
The volume of the accessory‐basal nucleus of the amygdala reduces with tau pathology in AD, but remains normal in non‐AD conditions.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082926
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- Article
Soluble biomarkers of Alzheimer's disease in plasma vary according to quantity of blood CNS derived extracellular vesicles.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076746
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- Article
Elucidating the Role of Brain Senescence and Telomere Attrition in Alzheimer's Disease Tauopathy.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078176
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- Article
Dysfunctional mitochondria during accelerated senescence and their impact on Alzheimer's disease neuropathology.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076710
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- Article
Outbreak of tauopathy in the olfactory system of PS19 mice: an early marker for Alzheimer's disease diagnosis?
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.071875
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- Article
Plasma biomarkers for Alzheimer's disease: from amyloid to CNS derived extracellular vesicles, overview of changes through age, sex and risk factor in control and AD populations.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.068853
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- Article
How to Build and to Protect the Neuromuscular Junction: The Role of the Glial Cell Line-Derived Neurotrophic Factor.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 1, p. 136, doi. 10.3390/ijms22010136
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- Publication type:
- Article
IDENTIFICATION OF NOVEL TARGETS FOR INHIBITING PRION-LIKE SEEDING AND PROPAGATION OF TAU PATHOLOGY IN VITRO AND IN VIVO.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1270, doi. 10.1016/j.jalz.2017.06.1901
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- Publication type:
- Article
MOLECULAR MECHANISMS OF ABETA-INDUCED TAU-PATHOLOGY: ANALYSIS OF CROSS-SEEDING OF ABETA AND TAU AND ITS ROLE IN PRION-LIKE PROPAGATION OF TAU-PATHOLOGY IN VITRO AND IN VIVO.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P385, doi. 10.1016/j.jalz.2016.06.722
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- Article
Structural features of the extracellular and juxta/transmembrane domains controlling APP dimerization, trafficking and processing
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- 2012
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- Abstract
Amyloid precursor protein regulates neuronal cholesterol turnover needed for synaptic activity
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- 2012
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- Abstract
The Kunitz protease inhibitor domain controls homodimerization of the amyloid precursor protein
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- 2010
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- Abstract
Epigenetic control of Aquaporin 1 expression by the amyloid precursor protein
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- 2009
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- Abstract
Analysis of the dimerization and metabolism of different APP isoforms
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- 2009
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- Abstract
Structural requirements for APP processing by γ-secretase
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- 2009
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- Abstract
P4-249: APP-dependent Aquaporin 1 expression in mouse embryonic fibroblasts
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- 2008
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- Abstract
P1-425: Dimerization and orientation of the transmembrane domain control APP amyloidogenic processing
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- 2008
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- Abstract
P2-053: Increase of the production of amyloid beta-peptide by lithium chloride is independent from its inhibition of GSK3
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- 2006
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- Abstract
P2-029: Distinct gamma-cleavages for the production of amyloid beta-peptide (Aβ) and APP intracellular domain (AICD)
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- 2006
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- Abstract
O2-03-02: Role of the transmembrane GxxxG motifs in the processing of human APP
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- 2006
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- Abstract
P2-053: Increase of the production of amyloid beta-peptide by lithium chloride is independent from its inhibition of GSK3
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- 2006
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- Publication type:
- Abstract
P2-029: Distinct gamma-cleavages for the production of amyloid beta-peptide (Aβ) and APP intracellular domain (AICD)
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- 2006
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- Publication type:
- Abstract
O2-03-02: Role of the transmembrane GxxxG motifs in the processing of human APP
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- 2006
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- Abstract
Specific post-translational modifications of soluble tau protein distinguishes Alzheimer's disease and primary tauopathies.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39328-1
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- Article
Glycines from the APP GXXXG/GXXXA Transmembrane Motifs Promote Formation of Pathogenic Aβ Oligomers in Cells.
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- Frontiers in Aging Neuroscience, 2016, p. 1, doi. 10.3389/fnagi.2016.00107
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- Publication type:
- Article
Epigenetic Regulations of Immediate Early Genes Expression Involved in Memory Formation by the Amyloid Precursor Protein of Alzheimer Disease.
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- PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0099467
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- Article
Epigenetic Induction of EGR-1 Expression by the Amyloid Precursor Protein during Exposure to Novelty.
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- PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0074305
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- Publication type:
- Article
Lactacystin decreases amyloid‐β peptide production by inhibiting β‐secretase activity.
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- Journal of Neuroscience Research, 2006, v. 84, n. 6, p. 1311
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- Article
Gamma-Secretase Inhibitor Activity of a Pterocarpus erinaceus Extract.
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- Neurodegenerative Diseases, 2014, v. 14, n. 1, p. 39, doi. 10.1159/000355557
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- Article
Contribution of the Endosomal-Lysosomal and Proteasomal Systems in Amyloid-β Precursor Protein Derived Fragments Processing.
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- Frontiers in Cellular Neuroscience, 2018, p. N.PAG, doi. 10.3389/fncel.2018.00435
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- Article
Presenilin-Deficient Neurons and Astrocytes Display Normal Mitochondrial Phenotypes.
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- Frontiers in Neuroscience, 2021, v. 14, p. N.PAG, doi. 10.3389/fnins.2020.586108
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- Article
Senescence-related impairment of autophagy induces toxic intraneuronal amyloid-β accumulation in a mouse model of amyloid pathology.
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- Acta Neuropathologica Communications, 2023, v. 11, n. 1, p. 1, doi. 10.1186/s40478-023-01578-x
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- Article
Specificity of presenilin‐1‐ and presenilin‐2‐dependent γ‐secretases towards substrate processing.
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- Journal of Cellular & Molecular Medicine, 2018, v. 22, n. 2, p. 823, doi. 10.1111/jcmm.13364
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- Article
APP-dependent glial cell line-derived neurotrophic factor gene expression drives neuromuscular junction formation.
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- FASEB Journal, 2016, v. 30, n. 5, p. 1696, doi. 10.1096/fj.15-278739
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- Article
Tauopathy contributes to synaptic and cognitive deficits in a murine model for Alzheimer's disease.
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- FASEB Journal, 2014, v. 28, n. 6, p. 2620, doi. 10.1096/fj.13-246702
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- Article
Structural features of the KPI domain control APP dimerization, trafficking, and processing.
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- FASEB Journal, 2012, v. 26, n. 2, p. 855, doi. 10.1096/fj.11-190207
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- Publication type:
- Article
Epigenetic control of aquaporin 1 expression by the amyloid precursor protein.
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- FASEB Journal, 2009, v. 23, n. 12, p. 4158, doi. 10.1096/fj.09-140012
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- Article
An evaluation of the self-assembly enhancing properties of cell-derived hexameric amyloid-β.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-90680-y
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- Publication type:
- Article
A mouse model of familial amyotrophic lateral sclerosis expressing a mutant superoxide dismutase 1 shows evidence of disordered transport in the vasopressin hypothalamo-neurohypophysial axis.
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- European Journal of Neuroscience, 1999, v. 11, n. 12, p. 4179, doi. 10.1046/j.1460-9568.1999.00840.x
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- Article
Depolarization regulates cyclin D1 degradation and neuronal apoptosis: a hypothesis about the role of the ubiquitin/proteasome signalling pathway.
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- European Journal of Neuroscience, 1999, v. 11, n. 2, p. 441, doi. 10.1046/j.1460-9568.1999.00451.x
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- Article
Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo.
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- Acta Neuropathologica, 2017, v. 133, n. 5, p. 731, doi. 10.1007/s00401-016-1663-9
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- Publication type:
- Article
Heterotypic seeding of Tau fibrillization by pre-aggregated Abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo.
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- Acta Neuropathologica, 2016, v. 131, n. 4, p. 549, doi. 10.1007/s00401-015-1525-x
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- Publication type:
- Article
Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice.
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- Acta Neuropathologica, 2015, v. 129, n. 6, p. 875, doi. 10.1007/s00401-015-1413-4
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- Publication type:
- Article
Structural Determinant of β-Amyloid Formation: From Transmembrane Protein Dimerization to β-Amyloid Aggregates.
- Published in:
- Biomedicines, 2022, v. 10, n. 11, p. 2753, doi. 10.3390/biomedicines10112753
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- Article
Comparison of plasma soluble and extracellular vesicles-associated biomarkers in Alzheimer's disease patients and cognitively normal individuals.
- Published in:
- Alzheimer's Research & Therapy, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13195-024-01508-6
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- Publication type:
- Article
Activation of phagocytic activity in astrocytes by reduced expression of the inflammasome component ASC and its implication in a mouse model of Alzheimer disease.
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- 2016
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- Publication type:
- journal article
Analysis by a highly sensitive split luciferase assay of the regions involved in APP dimerization and its impact on processing.
- Published in:
- FEBS Open Bio, 2015, v. 5, p. 763, doi. 10.1016/j.fob.2015.09.002
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- Publication type:
- Article