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Etiology matters - Genomic DNA Methylation Patterns in Three Rat Models of Acquired Epilepsy.
Published in:
Scientific Reports, 2016, p. 25668, doi. 10.1038/srep25668
By:
- Dębski, Konrad J.;
- Pitkanen, Asla;
- Puhakka, Noora;
- Bot, Anna M.;
- Khurana, Ishant;
- Harikrishnan, KN;
- Ziemann, Mark;
- Kaspi, Antony;
- El-Osta, Assam;
- Lukasiuk, Katarzyna;
- Kobow, Katja
Publication type:
Article
Prolonged Honeymoon Period in a Thai Patient with Adult-Onset Type 1 Diabetes Mellitus.
Published in:
Case Reports in Endocrinology, 2021, p. 1, doi. 10.1155/2021/3511281
By:
- Thewjitcharoen, Yotsapon;
- Wanothayaroj, Ekgaluck;
- Jaita, Haruethai;
- Nakasatien, Soontaree;
- Butadej, Siriwan;
- Khurana, Ishant;
- Maxwell, Scott;
- El-Osta, Assam;
- Chatchomchuan, Waralee;
- Krittiyawong, Sirinate;
- Himathongkam, Thep
Publication type:
Article
Pharmacological inhibition of human EZH2 can influence a regenerative β-like cell capacity with in vitro insulin release in pancreatic ductal cells.
Published in:
Clinical Epigenetics, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13148-023-01491-z
By:
- Naina Marikar, Safiya;
- Al-Hasani, Keith;
- Khurana, Ishant;
- Kaipananickal, Harikrishnan;
- Okabe, Jun;
- Maxwell, Scott;
- El-Osta, Assam
Publication type:
Article
Transcription factors <italic>Tp73</italic>, <italic>Cebpd</italic>, <italic>Pax6,</italic> and <italic>Spi1</italic> rather than DNA methylation regulate chronic transcriptomics changes after experimental traumatic brain injury.
Published in:
Acta Neuropathologica Communications, 2018, v. 6, p. 1, doi. 10.1186/s40478-018-0519-z
By:
- Lipponen, Anssi;
- El-Osta, Assam;
- Kaspi, Antony;
- Ziemann, Mark;
- Khurana, Ishant;
- KN, Harikrishnan;
- Navarro-Ferrandis, Vicente;
- Puhakka, Noora;
- Paananen, Jussi;
- Pitkänen, Asla
Publication type:
Article
Characterization of K562 cells: uncovering novel chromosomes, assessing transferrin receptor expression, and probing pharmacological therapies.
Published in:
Cellular & Molecular Life Sciences, 2023, v. 80, n. 9, p. 1, doi. 10.1007/s00018-023-04905-6
By:
- Karagiannis, Tom C.;
- Wall, Meaghan;
- Ververis, Katherine;
- Pitsillou, Eleni;
- Tortorella, Stephanie M.;
- Wood, Peter A.;
- Rafehi, Haloom;
- Khurana, Ishant;
- Maxwell, Scott S.;
- Hung, Andrew;
- Vongsvivut, Jitraporn;
- El-Osta, Assam
Publication type:
Article
Sulforaphane prevents and reverses allergic airways disease in mice via anti-inflammatory, antioxidant, and epigenetic mechanisms.
Published in:
Cellular & Molecular Life Sciences, 2022, v. 79, n. 11, p. 1, doi. 10.1007/s00018-022-04609-3
By:
- Royce, Simon G.;
- Licciardi, Paul V.;
- Beh, Raymond C.;
- Bourke, Jane E.;
- Donovan, Chantal;
- Hung, Andrew;
- Khurana, Ishant;
- Liang, Julia J.;
- Maxwell, Scott;
- Mazarakis, Nadia;
- Pitsillou, Eleni;
- Siow, Ya Yun;
- Snibson, Kenneth J.;
- Tobin, Mark J.;
- Ververis, Katherine;
- Vongsvivut, Jitraporn;
- Ziemann, Mark;
- Samuel, Chrishan S.;
- Tang, Mimi L. K.;
- El-Osta, Assam
Publication type:
Article
Intestinal microbiota regulates diabetes and cancer progression by IL-1β and NOX4 dependent signaling cascades.
Published in:
Cellular & Molecular Life Sciences, 2022, v. 79, n. 9, p. 1, doi. 10.1007/s00018-022-04485-x
By:
- Noureldein, Mohamed;
- Nawfal, Rashad;
- Bitar, Sara;
- Maxwell, Scott S.;
- Khurana, Ishant;
- Kassouf, Hala Kfoury;
- Khuri, Fadlo R.;
- El-Osta, Assam;
- Eid, Assaad A.
Publication type:
Article
Dynamic changes in the cardiac methylome during postnatal development.
Published in:
FASEB Journal, 2015, v. 29, n. 4, p. 1329, doi. 10.1096/fj.14-264093
By:
- Choon Boon Sim;
- Ziemann, Mark;
- Kaspi, Antony;
- Harikrishnan, K. N.;
- Ooi, Jenny;
- Khurana, Ishant;
- Chang, Lisa;
- Hudson, James E.;
- El-Osta, Assam;
- Porrello, Enzo R.
Publication type:
Article
Genomic DNA methylation distinguishes subtypes of human focal cortical dysplasia.
Published in:
Epilepsia (Series 4), 2019, v. 60, n. 6, p. 1091, doi. 10.1111/epi.14934
By:
- Kobow, Katja;
- Coras, Roland;
- Blümcke, Ingmar;
- Kudernatsch, Manfred;
- Hamer, Hajo;
- Kasper, Burkhard S.;
- Rössler, Karl;
- Conti, Valerio;
- Guerrini, Renzo;
- Ziemann, Mark;
- Khurana, Ishant;
- Kaspi, Antony;
- Kaipananickal, Harikrishnan;
- El‐Osta, Assam;
- Feucht, Martha;
- Mühlebner, Angelika;
- Aronica, Eleonora;
- Hainfellner, Johannes A.;
- Czech, Thomas;
- Pieper, Tom
Publication type:
Article
Diabetes mellitus and insulin resistance associated with Kabuki syndrome—A case report and literature review.
Published in:
Clinical Case Reports, 2022, v. 10, n. 4, p. 1, doi. 10.1002/ccr3.5736
By:
- Thewjitcharoen, Yotsapon;
- Wanothayaroj, Ekgaluck;
- Nakasatien, Soontaree;
- Krittiyawong, Sirinate;
- Khurana, Ishant;
- El‐Osta, Assam;
- Himathongkam, Thep
Publication type:
Article
DNA methylation patterns from peripheral blood separate coronary artery disease patients with and without heart failure.
Published in:
ESC Heart Failure, 2020, v. 7, n. 5, p. 2468, doi. 10.1002/ehf2.12810
By:
- Bain, Chris R.;
- Ziemann, Mark;
- Kaspi, Antony;
- Khan, Abdul Waheed;
- Taylor, Rachael;
- Trahair, Hugh;
- Khurana, Ishant;
- Kaipananickal, Harikrishnan;
- Wallace, Sophie;
- El‐Osta, Assam;
- Myles, Paul S.;
- Bozaoglu, Kiymet
Publication type:
Article
Valproic acid influences the expression of genes implicated with hyperglycaemia-induced complement and coagulation pathways.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-81794-4
By:
- Felisbino, Marina Barreto;
- Ziemann, Mark;
- Khurana, Ishant;
- Okabe, Jun;
- Al-Hasani, Keith;
- Maxwell, Scott;
- Harikrishnan, K. N.;
- de Oliveira, Camila Borges Martins;
- Mello, Maria Luiza S.;
- El-Osta, Assam
Publication type:
Article
Epigenetic evidence of an Ac/Dc axis by VPA and SAHA.
Published in:
Clinical Epigenetics, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13148-021-01050-4
By:
- Lunke, Sebastian;
- Maxwell, Scott;
- Khurana, Ishant;
- K.N., Harikrishnan;
- Okabe, Jun;
- Al-Hasani, Keith;
- El-Osta, Assam
Publication type:
Article
Deep sequencing reveals increased DNA methylation in chronic rat epilepsy.
Published in:
Acta Neuropathologica, 2013, v. 126, n. 5, p. 741, doi. 10.1007/s00401-013-1168-8
By:
- Kobow, Katja;
- Kaspi, Antony;
- Harikrishnan, K.;
- Kiese, Katharina;
- Ziemann, Mark;
- Khurana, Ishant;
- Fritzsche, Ina;
- Hauke, Jan;
- Hahnen, Eric;
- Coras, Roland;
- Mühlebner, Angelika;
- El-Osta, Assam;
- Blümcke, Ingmar
Publication type:
Article
EZH2 inhibitors promote β-like cell regeneration in young and adult type 1 diabetes donors.
Published in:
Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-023-01707-x
By:
- Al-Hasani, Keith;
- Marikar, Safiya Naina;
- Kaipananickal, Harikrishnan;
- Maxwell, Scott;
- Okabe, Jun;
- Khurana, Ishant;
- Karagiannis, Thomas;
- Liang, Julia J.;
- Mariana, Lina;
- Loudovaris, Thomas;
- Kay, Thomas;
- El-Osta, Assam
Publication type:
Article
EZH2 inhibitors promote β-like cell regeneration in young and adult type 1 diabetes donors.
Published in:
Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-023-01707-x
By:
- Al-Hasani, Keith;
- Marikar, Safiya Naina;
- Kaipananickal, Harikrishnan;
- Maxwell, Scott;
- Okabe, Jun;
- Khurana, Ishant;
- Karagiannis, Thomas;
- Liang, Julia J.;
- Mariana, Lina;
- Loudovaris, Thomas;
- Kay, Thomas;
- El-Osta, Assam
Publication type:
Article
Inhibition of pancreatic EZH2 restores progenitor insulin in T1D donor.
Published in:
Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01034-7
By:
- Al-Hasani, Keith;
- Khurana, Ishant;
- Mariana, Lina;
- Loudovaris, Thomas;
- Maxwell, Scott;
- Harikrishnan, K. N.;
- Okabe, Jun;
- Cooper, Mark E.;
- El-Osta, Assam
Publication type:
Article
Inhibition of pancreatic EZH2 restores progenitor insulin in T1D donor.
Published in:
Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01034-7
By:
- Al-Hasani, Keith;
- Khurana, Ishant;
- Mariana, Lina;
- Loudovaris, Thomas;
- Maxwell, Scott;
- Harikrishnan, K. N.;
- Okabe, Jun;
- Cooper, Mark E.;
- El-Osta, Assam
Publication type:
Article
Front cover: Diet during Pregnancy is Implicated in the Regulation of Hypothalamic RNA Methylation and Risk of Obesity in Offspring.
Published in:
Molecular Nutrition & Food Research, 2018, v. 62, n. 14, p. 1, doi. 10.1002/mnfr.201870074
By:
- Kaspi, Antony;
- Khurana, Ishant;
- Ziemann, Mark;
- Connor, Timothy;
- Spolding, Briana;
- Zimmet, Paul;
- Walder, Ken;
- El‐Osta, Assam
Publication type:
Article
Diet during Pregnancy is Implicated in the Regulation of Hypothalamic RNA Methylation and Risk of Obesity in Offspring.
Published in:
Molecular Nutrition & Food Research, 2018, v. 62, n. 14, p. 1, doi. 10.1002/mnfr.201800134
By:
- Kaspi, Antony;
- Khurana, Ishant;
- Ziemann, Mark;
- Connor, Timothy;
- Spolding, Briana;
- Zimmet, Paul;
- Walder, Ken;
- El‐Osta, Assam
Publication type:
Article
DNA methylation status correlates with adult β-cell regeneration capacity.
Published in:
NPJ Regenerative Medicine, 2021, v. 6, n. 1, p. 1, doi. 10.1038/s41536-021-00119-1
By:
- Khurana, Ishant;
- Al-Hasani, Keith;
- Maxwell, Scott;
- K.N., Harikrishnan;
- Okabe, Jun;
- Cooper, Mark E.;
- Collombat, Patrick;
- El-Osta, Assam
Publication type:
Article
SAHA attenuates Takotsubo-like myocardial injury by targeting an epigenetic Ac/Dc axis.
Published in:
2021
By:
- Khurana, Ishant;
- Maxwell, Scott;
- Royce, Simon;
- Mathiyalagan, Prabhu;
- Karagiannis, Tom;
- Mazarakis, Nadia;
- Vongsvivut, Jitraporn;
- K.N., Harikrishnan;
- Okabe, Jun;
- Al-Hasani, Keith;
- Samuel, Chrishan;
- El-Osta, Assam
Publication type:
Letter

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