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Retraction Note: Diet restriction inhibits apoptosis and HMGB1 oxidation and promotes inflammatory cell recruitment during acetaminophen hepatotoxicity.
- Published in:
- Molecular Medicine, 2020, v. 26, n. 1, p. 1, doi. 10.1186/s10020-020-00262-3
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- Publication type:
- Article
Expression of Concern to: Diet restriction inhibits apoptosis and HMGB1 oxidation and promotes inflammatory cell recruitment during acetaminophen hepatoxicity.
- Published in:
- 2020
- By:
- Publication type:
- Editorial
Managing the challenge of chemically reactive metabolites in drug development.
- Published in:
- 2011
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- Publication type:
- journal article
Immunological Principles of Adverse Drug Reactions.
- Published in:
- Drug Safety, 2000, v. 23, n. 6, p. 483, doi. 10.2165/00002018-200023060-00002
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- Publication type:
- Article
Drug metabolism and drug toxicity.
- Published in:
- Inflammopharmacology, 2001, v. 9, n. 1/2, p. 183, doi. 10.1163/156856001300248461
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- Publication type:
- Article
Co-precipitation of DEAE-dextran coated SPIONs: how synthesis conditions affect particle properties, stem cell labelling and MR contrast.
- Published in:
- Contrast Media & Molecular Imaging, 2016, v. 11, n. 5, p. 362, doi. 10.1002/cmmi.1700
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- Publication type:
- Article
Keratin-18 and micro RNA-122 complement alanine aminotransferase as novel safety biomarkers for drug-induced liver injury in two human cohorts.
- Published in:
- Liver International, 2014, v. 34, n. 3, p. 367, doi. 10.1111/liv.12322
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- Publication type:
- Article
Stem cell models as an in vitro model for predictive toxicology.
- Published in:
- Biochemical Journal, 2019, v. 476, n. 7, p. 1149, doi. 10.1042/BCJ20170780
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- Publication type:
- Article
Donor-Dependent and Other Nondefined Factors have Greater Influence on the Hepatic Phenotype than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte-Like Cells.
- Published in:
- Stem Cells Translational Medicine, 2017, v. 6, n. 8, p. 1751, doi. 10.1002/sctm.12187
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- Publication type:
- Article
Antigenicity and immunogenicity of sulphamethoxazole: demonstration of metabolism-dependent haptenation and T-cell proliferation in vivo.
- Published in:
- British Journal of Pharmacology, 2001, v. 133, n. 2, p. 295, doi. 10.1038/sj.bjp.0704074
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- Publication type:
- Article
Influence of reduced glutathione on the proliferative response of sulfamethoxazole-specific and sulfamethoxazole-metabolite-specific human CD4+ T-cells.
- Published in:
- British Journal of Pharmacology, 2001, v. 132, n. 3, p. 623, doi. 10.1038/sj.bjp.0703845
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- Publication type:
- Article
Cellular disposition of sulphamethoxazole and its metabolites: implications for hypersensitivity.
- Published in:
- 1999
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- Publication type:
- journal article
Assessment of the effect of malaria infection on hepatic clearance of dihydroartemisinin using rat liver perfusions and microsomes.
- Published in:
- 1998
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- Publication type:
- journal article
A Noninvasive Imaging Toolbox Indicates Limited Therapeutic Potential of Conditionally Activated Macrophages in a Mouse Model of Multiple Organ Dysfunction.
- Published in:
- Stem Cells International, 2019, p. 1, doi. 10.1155/2019/7386954
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- Publication type:
- Article
Role of Nrf2 in protection against acute kidney injury.
- Published in:
- Kidney International, 2013, v. 84, n. 6, p. 1090, doi. 10.1038/ki.2013.248
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- Publication type:
- Article
HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin.
- Published in:
- Nature Genetics, 2009, v. 41, n. 7, p. 816, doi. 10.1038/ng.379
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- Publication type:
- Article
Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy.
- Published in:
- Molecular Cancer, 2011, v. 10, n. 1, p. 37, doi. 10.1186/1476-4598-10-37
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- Publication type:
- Article
Identification of a 1,2,4,5-Tetraoxane Antimalarial Drug-Development Candidate (RKA 182) with Superior Properties to the Semisynthetic Artemisinins.
- Published in:
- Angewandte Chemie, 2010, v. 122, n. 33, p. 5829, doi. 10.1002/ange.201001026
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- Publication type:
- Article
Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease.
- Published in:
- Scientific Reports, 2016, p. 25187, doi. 10.1038/srep25187
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- Publication type:
- Article
Measures of kidney function by minimally invasive techniques correlate with histological glomerular damage in SCID mice with adriamycin-induced nephropathy.
- Published in:
- Scientific Reports, 2015, p. 13601, doi. 10.1038/srep13601
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- Publication type:
- Article
In Vivo Tumorigenicity of the 20q11.21 Amplicon in an Engraftment Model of hPSCs and Differentiated Liver Cells.
- Published in:
- Journal of Stem Cells & Regenerative Medicine (JSRM), 2023, v. 19, n. 1, p. 3, doi. 10.46582/jsrm.1901002
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- Publication type:
- Article
Mechanism-Based Urinary Biomarkers to Identify the Potential for Aminoglycoside-Induced Nephrotoxicity in Premature Neonates: A Proof-of-Concept Study.
- Published in:
- PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0043809
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- Publication type:
- Article
Glutathione- S-transferase pi as a model protein for the characterisation of chemically reactive metabolites.
- Published in:
- Proteomics, 2008, v. 8, n. 2, p. 301, doi. 10.1002/pmic.200700843
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- Publication type:
- Article
A method for the rapid depletion of albumin and immunoglobulin from human plasma.
- Published in:
- Proteomics, 2004, v. 4, n. 10, p. 3107, doi. 10.1002/pmic.200300815
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- Publication type:
- Article
Protein expression profiling of glutathione S-transferase pi null mice as a strategy to identify potential markers of resistance to paracetamol-induced toxicity in the liver.
- Published in:
- Proteomics, 2003, v. 3, n. 2, p. 191, doi. 10.1002/pmic.200390028
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- Publication type:
- Article
Evaluation of clinical and genetic factors in the population pharmacokinetics of carbamazepine.
- Published in:
- British Journal of Clinical Pharmacology, 2021, v. 87, n. 6, p. 2572, doi. 10.1111/bcp.14667
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- Publication type:
- Article
Dose‐linearity of the pharmacokinetics of an intravenous [<sup>14</sup>C]midazolam microdose in children.
- Published in:
- British Journal of Clinical Pharmacology, 2019, v. 85, n. 10, p. 2332, doi. 10.1111/bcp.14047
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- Publication type:
- Article
Observational infant exploratory [<sup>14</sup>C]-paracetamol pharmacokinetic microdose/therapeutic dose study with accelerator mass spectrometry bioanalysis.
- Published in:
- British Journal of Clinical Pharmacology, 2015, v. 80, n. 1, p. 157, doi. 10.1111/bcp.12597
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- Publication type:
- Article
Early detection of paracetamol toxicity using circulating liver microRNA and markers of cell necrosis.
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- British Journal of Clinical Pharmacology, 2014, v. 77, n. 5, p. 904, doi. 10.1111/bcp.12214
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- Publication type:
- Article
Stem cell-derived hepatocytes as a predictive model for drug-induced liver injury: are we there yet?
- Published in:
- British Journal of Clinical Pharmacology, 2013, v. 75, n. 4, p. 885, doi. 10.1111/j.1365-2125.2012.04360.x
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- Publication type:
- Article
The population pharmacokinetics of R- and S-warfarin: effect of genetic and clinical factors.
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- British Journal of Clinical Pharmacology, 2012, v. 73, n. 1, p. 66, doi. 10.1111/j.1365-2125.2011.04051.x
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- Publication type:
- Article
Extract of Ginkgo biloba induces glutamate cysteine ligase catalytic subunit (GCLC).
- Published in:
- Phytotherapy Research, 2008, v. 22, n. 3, p. 367, doi. 10.1002/ptr.2328
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- Publication type:
- Article
The Generation, Detection, and Effects of Reactive Drug Metabolites.
- Published in:
- Medicinal Research Reviews, 2013, v. 33, n. 5, p. 985, doi. 10.1002/med.21273
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- Publication type:
- Article
Model-based identification of TNFα-induced IKKβ-mediated and IκBα-mediated regulation of NFκB signal transduction as a tool to quantify the impact of drug-induced liver injury compounds.
- Published in:
- NPJ Systems Biology & Applications, 2018, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41540-018-0058-z
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- Publication type:
- Article
Circulating levels of miR-122 increase post-mortem, particularly following lethal dosing with pentobarbital sodium: implications for pre-clinical liver injury studies.
- Published in:
- Toxicology Research, 2017, v. 6, n. 4, p. 406, doi. 10.1039/c6tx00442c
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- Publication type:
- Article
Smad4 loss is associated with fewer S100A8-positive monocytes in colorectal tumors and attenuated response to S100A8 in colorectal and pancreatic cancer cells.
- Published in:
- Carcinogenesis, 2010, v. 31, n. 9, p. 1541, doi. 10.1093/carcin/bgq137
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- Publication type:
- Article
Characterization of p-Phenylenediamine–Albumin Binding Sites and T-Cell Responses to Hapten-Modified Protein.
- Published in:
- Journal of Investigative Dermatology, 2010, v. 130, n. 3, p. 732, doi. 10.1038/jid.2009.271
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- Publication type:
- Article
Measurement of CD4+ and CD8+ T-Lymphocyte Cytokine Secretion and Gene Expression Changes in p-Phenylenediamine Allergic Patients and Tolerant Individuals.
- Published in:
- Journal of Investigative Dermatology, 2010, v. 130, n. 1, p. 161, doi. 10.1038/jid.2009.187
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- Publication type:
- Article
Assessing technical and biological variation in SWATH-MS-based proteomic analysis of chronic lymphocytic leukaemia cells.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-82609-2
- By:
- Publication type:
- Article
Induction of P-glycoprotein in lymphocytes by carbamazepine and rifampicin: the role of nuclear hormone response elements.
- Published in:
- British Journal of Clinical Pharmacology, 2006, v. 62, n. 2, p. 237, doi. 10.1111/j.1365-2125.2006.02587.x
- By:
- Publication type:
- Article
Relationship between the C<sub>3435</sub>T and G<sub>2677</sub>T(A) polymorphisms in theABCB1gene and P-glycoprotein expression in human liver.
- Published in:
- British Journal of Clinical Pharmacology, 2005, v. 59, n. 3, p. 365, doi. 10.1111/j.1365-2125.2005.02229.x
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- Publication type:
- Article
Adverse drug reactions: back to the future.
- Published in:
- British Journal of Clinical Pharmacology, 2003, v. 55, n. 5, p. 486, doi. 10.1046/j.1365-2125.2003.01847.x
- By:
- Publication type:
- Article
Slow acetylator phenotype and genotype in HIV-positive patients with sulphamethoxazole hypersensitivity.
- Published in:
- British Journal of Clinical Pharmacology, 2003, v. 55, n. 2, p. 158, doi. 10.1046/j.1365-2125.2003.01754.x
- By:
- Publication type:
- Article
Carbamazepine is not a substrate for P-glycoprotein.
- Published in:
- British Journal of Clinical Pharmacology, 2001, v. 51, n. 4, p. 345, doi. 10.1046/j.1365-2125.2001.01359.x
- By:
- Publication type:
- Article
Metabolism of lamotrigine to a chemically reactive metabolite(s) in vivo: possible role in cutaneous reactions.
- Published in:
- British Journal of Clinical Pharmacology, 1999, v. 48, n. 6, p. 876P
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- Publication type:
- Article
Safety assessment of peroxide antimalarials: clinical and chemical perspectives.
- Published in:
- British Journal of Clinical Pharmacology, 1998, v. 46, n. 6, p. 521, doi. 10.1046/j.1365-2125.1998.00838.x
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- Publication type:
- Article
The effect of fluconazole and ketoconazole on the metabolism of sulphamethoxazole.
- Published in:
- British Journal of Clinical Pharmacology, 1996, v. 42, n. 3, p. 347, doi. 10.1046/j.1365-2125.1996.40110.x
- By:
- Publication type:
- Article
Safety perspectives on presently considered drugs for the treatment of COVID-19.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Value of monitoring Nrf2 activity for the detection of chemical and oxidative stress.
- Published in:
- Biochemical Society Transactions, 2015, v. 43, n. 4, p. 657, doi. 10.1042/BST20150044
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- Publication type:
- Article
Examination of the Cytotoxic and Embryotoxic Potential and Underlying Mechanisms of Next-Generation Synthetic Trioxolane and Tetraoxane Antimalarials.
- Published in:
- Molecular Medicine, 2012, v. 18, n. 7, p. 1045, doi. 10.2119/molmed.2012.00154
- By:
- Publication type:
- Article