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The Biology and Biochemistry of Kynurenic Acid, a Potential Nutraceutical with Multiple Biological Effects.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 16, p. 9082, doi. 10.3390/ijms25169082
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- Article
Computational cluster validation in post-genomic data analysis.
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- Bioinformatics, 2005, v. 21, n. 15, p. 3201, doi. 10.1093/bioinformatics/bti517
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- Article
MEG (Model Extender for Gepasi): a program for the modelling of complex, heterogeneous, cellular systems.
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- Bioinformatics, 2001, v. 17, n. 3, p. 288, doi. 10.1093/bioinformatics/17.3.288
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- Article
Enhancing Drug Efficacy and Therapeutic Index through Cheminformatics-Based Selection of Small Molecule Binary Weapons That Improve Transporter-Mediated Targeting: A Cytotoxicity System Based on Gemcitabine.
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- Frontiers in Pharmacology, 2017, v. 8, p. 1, doi. 10.3389/fphar.2017.00155
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- Article
MetMaxStruct: A Tversky-Similarity-Based Strategy for Analysing the (Sub)Structural Similarities of Drugs and Endogenous Metabolites.
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- Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00266
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- Article
Dimethyl fumarate eliminates differentially culturable Mycobacterium tuberculosis in an intranasal murine model of tuberculosis.
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- Frontiers in Cellular & Infection Microbiology, 2022, v. 12, p. 1, doi. 10.3389/fcimb.2022.957287
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- Article
Dimethyl fumarate eliminates differentially culturable Mycobacterium tuberculosis in an intranasal murine model of tuberculosis.
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- Frontiers in Cellular & Infection Microbiology, 2022, v. 12, p. 1, doi. 10.3389/fcimb.2022.957287
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Lipopolysaccharide-binding protein (LBP) can reverse the amyloid state of fibrin seen or induced in Parkinson's disease.
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- PLoS ONE, 2018, v. 13, n. 3, p. 1, doi. 10.1371/journal.pone.0192121
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Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases.
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- BMC Medical Genomics, 2009, v. 2, p. 1, doi. 10.1186/1755-8794-2-2
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Identification of transporters involved in aromatic compounds tolerance through screening of transporter deletion libraries.
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- Microbial Biotechnology, 2024, v. 17, n. 4, p. 1, doi. 10.1111/1751-7915.14460
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- Article
Engineering ergothioneine production in Yarrowia lipolytica.
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- FEBS Letters, 2022, v. 596, n. 10, p. 1356, doi. 10.1002/1873-3468.14239
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- Article
Major involvement of bacterial components in rheumatoid arthritis and its accompanying oxidative stress, systemic inflammation and hypercoagulability.
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- Experimental Biology & Medicine, 2017, v. 242, n. 4, p. 355, doi. 10.1177/1535370216681549
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- Article
Path2Models: large-scale generation of computational models from biochemical pathway maps.
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- BMC Systems Biology, 2013, v. 7, n. 1, p. 3, doi. 10.1186/1752-0509-7-116
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- Article
Improving metabolic flux predictions using absolute gene expression data.
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- BMC Systems Biology, 2012, v. 6, n. 1, p. 73, doi. 10.1186/1752-0509-6-73
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- Article
Interactions among oscillatory pathways in NF-kappa B signaling.
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- BMC Systems Biology, 2011, v. 5, n. 1, p. 23, doi. 10.1186/1752-0509-5-23
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- Article
Predicting the points of interaction of small molecules in the NF-ΚΒ pathway.
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- BMC Systems Biology, 2011, v. 5, n. 1, p. 32, doi. 10.1186/1752-0509-5-32
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- Article
Further developments towards a genome-scale metabolic model of yeast.
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- BMC Systems Biology, 2010, v. 4, p. 145, doi. 10.1186/1752-0509-4-145
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- Article
The inhibition by CO<sub>2</sub> of the growth and metabolism of micro-organisms.
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- Journal of Applied Microbiology, 1989, v. 67, n. 2, p. 109, doi. 10.1111/j.1365-2672.1989.tb03387.x
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- Article
SpeedyGenes: an improved gene synthesis method for the efficient production of error-corrected, synthetic protein libraries for directed evolution.
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- PEDS: Protein Engineering, Design & Selection, 2014, v. 27, n. 9, p. 273, doi. 10.1093/protein/gzu029
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Sample preparation in matrix-assisted laser desorption/ionization mass spectrometry of whole bacterial cells and the detection of high mass (>20 kDa) proteins.
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- Rapid Communications in Mass Spectrometry: RCM, 2002, v. 16, n. 13, p. 1276, doi. 10.1002/rcm.713
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- Article
Data-independent LC-MS/MS analysis of ME/CFS plasma reveals a dysregulated coagulation system, endothelial dysfunction, downregulation of complement machinery.
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- Cardiovascular Diabetology, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12933-024-02315-x
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- Article
Membrane Transporters Involved in the Antimicrobial Activities of Pyrithione in Escherichia coli.
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- Molecules, 2021, v. 26, n. 19, p. 5826, doi. 10.3390/molecules26195826
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The Transporter-Mediated Cellular Uptake and Efflux of Pharmaceutical Drugs and Biotechnology Products: How and Why Phospholipid Bilayer Transport Is Negligible in Real Biomembranes.
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- Molecules, 2021, v. 26, n. 18, p. 5629, doi. 10.3390/molecules26185629
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FragNet, a Contrastive Learning-Based Transformer Model for Clustering, Interpreting, Visualizing, and Navigating Chemical Space.
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- Molecules, 2021, v. 26, n. 7, p. 2065, doi. 10.3390/molecules26072065
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- Article
VAE-Sim: A Novel Molecular Similarity Measure Based on a Variational Autoencoder.
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- Molecules, 2020, v. 25, n. 15, p. 3446, doi. 10.3390/molecules25153446
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Functional genomic hypothesis generation and experimentation by a robot scientist.
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- Nature, 2004, v. 427, n. 6971, p. 247, doi. 10.1038/nature02236
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- Article
Analysis of a Library of Escherichia coli Transporter Knockout Strains to Identify Transport Pathways of Antibiotics.
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- Antibiotics (2079-6382), 2022, v. 11, n. 8, p. 1, doi. 10.3390/antibiotics11081129
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- Article
A Quantitative Survey of Bacterial Persistence in the Presence of Antibiotics: Towards Antipersister Antimicrobial Discovery.
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- Antibiotics (2079-6382), 2020, v. 9, n. 8, p. 508, doi. 10.3390/antibiotics9080508
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- Article
Serum amyloid A binds to fibrin(ogen), promoting fibrin amyloid formation.
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- Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-39056-x
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- Article
Correlative Light-Electron Microscopy detects lipopolysaccharide and its association with fibrin fibres in Parkinson’s Disease, Alzheimer’s Disease and Type 2 Diabetes Mellitus.
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- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-35009-y
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- Article
Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome: the biology of a neglected disease.
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- Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1386607
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- Article
High ferritin levels have major effects on the morphology of erythrocytes in Alzheimer's disease.
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- Frontiers in Aging Neuroscience, 2013, v. 5, p. 1, doi. 10.3389/fnagi.2013.00088
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- Article
Serum ferritin is an important inflammatory disease marker, as it is mainly a leakage product from damaged cells.
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- Metallomics, 2014, v. 6, n. 4, p. 748, doi. 10.1039/c3mt00347g
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Harnessing the yeast Saccharomyces cerevisiae for the production of fungal secondary metabolites.
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- Essays in Biochemistry, 2021, v. 65, n. 2, p. 377, doi. 10.1042/EBC20200137
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SYNBIOCHEM - a SynBio foundry for the biosynthesis and sustainable production of fine and speciality chemicals.
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- Biochemical Society Transactions, 2016, v. 44, n. 3, p. 675, doi. 10.1042/BST20160009
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- Article
Erythrocyte, Platelet, Serum Ferritin, and P-Selectin Pathophysiology Implicated in Severe Hypercoagulation and Vascular Complications in COVID-19.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 21, p. 8234, doi. 10.3390/ijms21218234
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- Article
Covid-19: The Rollercoaster of Fibrin(Ogen), D-Dimer, Von Willebrand Factor, P-Selectin and Their Interactions with Endothelial Cells, Platelets and Erythrocytes.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 14, p. 5168, doi. 10.3390/ijms21145168
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- Article
Proteomics of fibrin amyloid microclots in long COVID/post-acute sequelae of COVID-19 (PASC) shows many entrapped pro-inflammatory molecules that may also contribute to a failed fibrinolytic system.
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- Cardiovascular Diabetology, 2022, v. 21, n. 1, p. 1, doi. 10.1186/s12933-022-01623-4
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- Article
Prevalence of symptoms, comorbidities, fibrin amyloid microclots and platelet pathology in individuals with Long COVID/Post-Acute Sequelae of COVID-19 (PASC).
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- Cardiovascular Diabetology, 2022, v. 21, n. 1, p. 1, doi. 10.1186/s12933-022-01579-5
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- Article
Persistent clotting protein pathology in Long COVID/Post-Acute Sequelae of COVID-19 (PASC) is accompanied by increased levels of antiplasmin.
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- Cardiovascular Diabetology, 2021, v. 20, n. 1, p. 1, doi. 10.1186/s12933-021-01359-7
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- Article
Extracting semantically enriched events from biomedical literature.
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- BMC Bioinformatics, 2012, v. 13, n. 1, p. 108, doi. 10.1186/1471-2105-13-108
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Systematic integration of experimental data and models in systems biology.
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- BMC Bioinformatics, 2010, v. 11, p. 582, doi. 10.1186/1471-2105-11-582
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- Article
The Use of Dielectric Permittivity for the Control of the Biomass Level during Biotransformations of Toxic Substrates in Continuous Culture.
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- Biotechnology Progress, 1995, v. 11, n. 1, p. 64, doi. 10.1021/bp00031a009
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Metabolic footprinting and systems biology: the medium is the message.
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- Nature Reviews Microbiology, 2005, v. 3, n. 7, p. 557, doi. 10.1038/nrmicro1177
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- Article
Data sharing: A Long COVID perspective, challenges, and road map for the future.
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- South African Journal of Science, 2023, v. 119, n. 5/6, p. 73, doi. 10.17159/sajs.2023/14719
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- Article
Publishing: Reviews turn facts into understanding.
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- Nature, 2012, v. 490, n. 7418, p. 37, doi. 10.1038/490037e
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- Article
A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites.
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- Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0520-5
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- Article
Identification and Engineering of Transporters for Efficient Melatonin Production in Escherichia coli.
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- Frontiers in Microbiology, 2022, p. 1, doi. 10.3389/fmicb.2022.880847
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- Article
Breeding crop plants with deep roots: their role in sustainable carbon, nutrient and water sequestration.
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- Annals of Botany, 2011, v. 108, n. 3, p. 407, doi. 10.1093/aob/mcr175
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Here is the evidence, now what is the hypothesis? The complementary roles of inductive and hypothesis-driven science in the post-genomic era.
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- BioEssays, 2004, v. 26, n. 1, p. 99, doi. 10.1002/bies.10385
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- Article