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GalNAc-Lipid nanoparticles enable non-LDLR dependent hepatic delivery of a CRISPR base editing therapy.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37465-1
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- Publication type:
- Article
Algorithms for Assessing Cardiovascular Risk in Women.
- Published in:
- 2007
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- Publication type:
- Letter
A null mutation in does not ANGPTL8 associate with either plasma glucose or type 2 diabetes in humans.
- Published in:
- BMC Endocrine Disorders, 2016, v. 16, p. 1, doi. 10.1186/s12902-016-0088-8
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- Publication type:
- Article
Exome sequencing and complex disease: practical aspects of rare variant association studies.
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- Human Molecular Genetics, 2012, v. 21, n. R1, p. R1
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- Publication type:
- Article
Aggregate penetrance of genomic variants for actionable disorders in European and African Americans.
- Published in:
- Science Translational Medicine, 2016, v. 8, n. 364, p. 1, doi. 10.1126/scitranslmed.aag2367
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- Publication type:
- Article
Association of Low-Density Lipoprotein Cholesterol-Related Genetic Variants With Aortic Valve Calcium and Incident Aortic Stenosis.
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- JAMA: Journal of the American Medical Association, 2014, v. 312, n. 17, p. 1764, doi. 10.1001/jama.2014.13959
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- Publication type:
- Article
Genetic Variants Associated With Cardiac Structure and Function.
- Published in:
- JAMA: Journal of the American Medical Association, 2009, v. 302, n. 2, p. 168, doi. 10.1001/jama.2009.978-a
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- Publication type:
- Article
Low coverage whole genome sequencing enables accurate assessment of common variants and calculation of genome-wide polygenic scores.
- Published in:
- Genome Medicine, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13073-019-0682-2
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- Publication type:
- Article
1937-P: ALK-7: A Validated Target for the Treatment of Obesity.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1937-P
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- Publication type:
- Article
Genetic Variation at the Sulfonylurea Receptor, Type 2 Diabetes, and Coronary Heart Disease.
- Published in:
- 2017
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- Publication type:
- journal article
A 500K Genuine-Wide Association Study for Blood Lipids and Apolipoproteins.
- Published in:
- Diabetes, 2007, v. 56, p. A235
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- Publication type:
- Article
Association Study of Common Genetic Variants and HIV-1 Acquisition in 6,300 Infected Cases and 7,200 Controls.
- Published in:
- PLoS Pathogens, 2013, v. 9, n. 7, p. 1, doi. 10.1371/journal.ppat.1003515
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- Publication type:
- Article
Mendelian Randomization.
- Published in:
- 2017
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- Publication type:
- journal article
Genetic Predisposition to Abdominal Obesity and Cardiometabolic Risk-Reply.
- Published in:
- 2017
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- Publication type:
- letter
Genetic Predisposition to Abdominal Adiposity and Cardiometabolic Risk--Reply.
- Published in:
- 2017
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- Publication type:
- Letter to the Editor
Genetic Association of Waist-to-Hip Ratio With Cardiometabolic Traits, Type 2 Diabetes, and Coronary Heart Disease.
- Published in:
- 2017
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- Publication type:
- journal article
Meta-analysis of gene-level tests for rare variant association.
- Published in:
- Nature Genetics, 2014, v. 46, n. 2, p. 200, doi. 10.1038/ng.2852
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- Publication type:
- Article
Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis.
- Published in:
- Nature Genetics, 2012, v. 44, n. 5, p. 483, doi. 10.1038/ng.2232
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- Publication type:
- Article
Comparing strategies to fine-map the association of common SNPs at chromosome 9p21 with type 2 diabetes and myocardial infarction.
- Published in:
- Nature Genetics, 2011, v. 43, n. 8, p. 801, doi. 10.1038/ng.871
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- Publication type:
- Article
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.
- Published in:
- Nature Genetics, 2011, v. 43, n. 4, p. 333, doi. 10.1038/ng.784
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- Publication type:
- Article
Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia.
- Published in:
- Nature Genetics, 2010, v. 42, n. 8, p. 684, doi. 10.1038/ng.628
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- Publication type:
- Article
New susceptibility locus for coronary artery disease on chromosome 3q22.3.
- Published in:
- Nature Genetics, 2009, v. 41, n. 3, p. 280, doi. 10.1038/ng.307
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- Publication type:
- Article
Association of common variants in NPPA and NPPB with circulating natriuretic peptides and blood pressure.
- Published in:
- Nature Genetics, 2009, v. 41, n. 3, p. 348, doi. 10.1038/ng.328
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- Publication type:
- Article
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.
- Published in:
- Nature Genetics, 2009, v. 41, n. 3, p. 334, doi. 10.1038/ng.327
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- Publication type:
- Article
Common variants at 30 loci contribute to polygenic dyslipidemia.
- Published in:
- Nature Genetics, 2009, v. 41, n. 1, p. 56, doi. 10.1038/ng.291
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- Publication type:
- Article
Corrigendum: Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.
- Published in:
- 2008
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- Publication type:
- Correction notice
Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.
- Published in:
- Nature Genetics, 2008, v. 40, n. 2, p. 189, doi. 10.1038/ng.75
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- Publication type:
- Article
Systematic Cell-Based Phenotyping of Missense Alleles Empowers Rare Variant Association Studies: A Case for LDLR and Myocardial Infarction.
- Published in:
- PLoS Genetics, 2015, v. 11, n. 2, p. 1, doi. 10.1371/journal.pgen.1004855
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- Publication type:
- Article
Mining the LIPG Allelic Spectrum Reveals the Contribution of Rare and Common Regulatory Variants to HDL Cholesterol.
- Published in:
- PLoS Genetics, 2011, v. 7, n. 12, p. 1, doi. 10.1371/journal.pgen.1002393
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- Publication type:
- Article
Testing for an Unusual Distribution of Rare Variants.
- Published in:
- PLoS Genetics, 2011, v. 7, n. 3, p. 1, doi. 10.1371/journal.pgen.1001322
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- Publication type:
- Article
Forty-Three Loci Associated with Plasma Lipoprotein Size, Concentration, and Cholesterol Content in Genome-Wide Analysis.
- Published in:
- PLoS Genetics, 2009, v. 5, n. 11, p. 1, doi. 10.1371/journal.pgen.1000730
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- Publication type:
- Article
Genetic Differences between the Determinants of Lipid Profile Phenotypes in African and European Americans: The Jackson Heart Study.
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- PLoS Genetics, 2009, v. 5, n. 1, p. 1, doi. 10.1371/journal.pgen.1000342
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- Publication type:
- Article
Inflammation, kidney function and albuminuria in the Framingham Offspring cohort.
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- Nephrology Dialysis Transplantation, 2011, v. 26, n. 3, p. 920, doi. 10.1093/ndt/gfq471
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- Publication type:
- Article
Pericardial Fat Volume Correlates With Inflammatory Markers: The Framingham Heart Study.
- Published in:
- Obesity (19307381), 2010, v. 18, n. 5, p. 1039, doi. 10.1038/oby.2009.343
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- Publication type:
- Article
PAI-1 Gene 4G/5G Polymorphism and Risk of Type 2 Diabetes in a Population-based Sample<sup>*</sup>.
- Published in:
- Obesity (19307381), 2006, v. 14, n. 5, p. 753, doi. 10.1038/oby.2006.85
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- Publication type:
- Article
O2-06-03: Inflammatory biomarkers are associated with total brain volume: The Framingham Heart Study
- Published in:
- 2006
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- Publication type:
- Abstract
O2-06-03: Inflammatory biomarkers are associated with total brain volume: The Framingham Heart Study
- Published in:
- 2006
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- Publication type:
- Abstract
Clinical and Genetic Correlates of Serum Aldosterone in the Community: The Framingham Heart Study
- Published in:
- American Journal of Hypertension, 2005, v. 18, n. 5, p. 657, doi. 10.1016/j.amjhyper.2004.12.005
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- Publication type:
- Article
Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-17374-3
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- Publication type:
- Article
Best Practices and Joint Calling of the HumanExome BeadChip: The CHARGE Consortium.
- Published in:
- PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0068095
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- Publication type:
- Article
Hypothesis-Based Analysis of Gene-Gene Interactions and Risk of Myocardial Infarction.
- Published in:
- PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0041730
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- Publication type:
- Article
Increased plasma osteoprotegerin concentrations are associated with indices of bone strength of the hip.
- Published in:
- 2008
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- Publication type:
- journal article
On the interpretation of genetic association studies.
- Published in:
- European Heart Journal, 2004, v. 25, n. 16, p. 1378, doi. 10.1016/j.ehj.2004.06.035
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- Publication type:
- Article
Vitamin K and Vitamin D Status: Associations with Inflammatory Markers in the Framingham Offspring Study.
- Published in:
- American Journal of Epidemiology, 2008, v. 167, n. 3, p. 313
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- Publication type:
- Article
Triglyceride response to an intensive lifestyle intervention is enhanced in carriers of the GCKR Pro446Leu polymorphism.
- Published in:
- 2011
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- Publication type:
- journal article
Neurocognitive trajectory and proteomic signature of inherited risk for Alzheimer's disease.
- Published in:
- PLoS Genetics, 2022, v. 18, n. 9, p. 1, doi. 10.1371/journal.pgen.1010294
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- Publication type:
- Article
Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism.
- Published in:
- Journal of Clinical Investigation, 2012, v. 122, n. 8, p. 2807, doi. 10.1172/JCI63563
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- Publication type:
- Article
Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism.
- Published in:
- Journal of Clinical Investigation, 2012, v. 122, n. 7, p. 1, doi. 10.1172/JCI63563
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- Publication type:
- Article
Trib1 is a lipid- and myocardial infarction-associated gene that regulates hepatic lipogenesis and VLDL production in mice.
- Published in:
- 2010
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- Publication type:
- journal article
Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans.
- Published in:
- 2009
- By:
- Publication type:
- journal article