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Evaluating Targeted Therapies in Ovarian Cancer Metabolism: Novel Role for PCSK9 and Second Generation mTOR Inhibitors.
Published in:
Cancers, 2021, v. 13, n. 15, p. 3727, doi. 10.3390/cancers13153727
By:
- Jacome Sanz, Dafne;
- Raivola, Juuli;
- Karvonen, Hanna;
- Arjama, Mariliina;
- Barker, Harlan;
- Murumägi, Astrid;
- Ungureanu, Daniela
Publication type:
Article
Targeting Wnt signaling pseudokinases in hematological cancers.
Published in:
European Journal of Haematology, 2018, v. 101, n. 4, p. 457, doi. 10.1111/ejh.13137
By:
- Karvonen, Hanna;
- Perttilä, Robert;
- Niininen, Wilhelmiina;
- Barker, Harlan;
- Ungureanu, Daniela
Publication type:
Article
New insights into the molecular mechanisms of ROR1, ROR2, and PTK7 signaling from the proteomics and pharmacological modulation of ROR1 interactome.
Published in:
Cellular & Molecular Life Sciences, 2022, v. 79, n. 5, p. 1, doi. 10.1007/s00018-022-04301-6
By:
- Raivola, Juuli;
- Dini, Alice;
- Salokas, Kari;
- Karvonen, Hanna;
- Niininen, Wilhelmiina;
- Piki, Emilia;
- Varjosalo, Markku;
- Ungureanu, Daniela
Publication type:
Article
Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases.
Published in:
FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.02446
By:
- Sheetz, Joshua;
- Mathea, Sebastian;
- Karvonen, Hanna;
- Malhotra, Ketan;
- Chatterjee, Deep;
- Niininen, Wilhelmiina;
- Perttila, Robert;
- Preuss, Franziska;
- Suresh, Krishna;
- Stayrook, Steven;
- Tsutsui, Yuko;
- Radhakrishnan, Ravi;
- Ungureanu, Daniela;
- Knapp, Stefan;
- Lemmon, Mark
Publication type:
Article
Multiomics characterization implicates PTK7 in ovarian cancer EMT and cell plasticity and offers strategies for therapeutic intervention.
Published in:
Cell Death & Disease, 2022, v. 13, n. 8, p. 1, doi. 10.1038/s41419-022-05161-5
By:
- Raivola, Juuli;
- Dini, Alice;
- Karvonen, Hanna;
- Piki, Emilia;
- Salokas, Kari;
- Niininen, Wilhelmiina;
- Kaleva, Laura;
- Zhang, Kaiyang;
- Arjama, Mariliina;
- Gudoityte, Greta;
- Seashore-Ludlow, Brinton;
- Varjosalo, Markku;
- Kallioniemi, Olli;
- Hautaniemi, Sampsa;
- Murumägi, Astrid;
- Ungureanu, Daniela
Publication type:
Article
Glucocorticoids induce differentiation and chemoresistance in ovarian cancer by promoting ROR1-mediated stemness.
Published in:
Cell Death & Disease, 2020, v. 11, n. 9, p. 1, doi. 10.1038/s41419-020-03009-4
By:
- Karvonen, Hanna;
- Arjama, Mariliina;
- Kaleva, Laura;
- Niininen, Wilhelmiina;
- Barker, Harlan;
- Koivisto-Korander, Riitta;
- Tapper, Johanna;
- Pakarinen, Päivi;
- Lassus, Heini;
- Loukovaara, Mikko;
- Bützow, Ralf;
- Kallioniemi, Olli;
- Murumägi, Astrid;
- Ungureanu, Daniela
Publication type:
Article
Targeting ROR1 identifies new treatment strategies in hematological cancers.
Published in:
Biochemical Society Transactions, 2017, v. 45, n. 2, p. 457, doi. 10.1042/BST20160272
By:
- Karvonen, Hanna;
- Niininen, Wilhelmiina;
- Murumägi, Astrid;
- Ungureanu, Daniela
Publication type:
Article
Molecular Mechanisms Associated with ROR1-Mediated Drug Resistance: Crosstalk with Hippo-YAP/TAZ and BMI-1 Pathways.
Published in:
Cells (2073-4409), 2019, v. 8, n. 8, p. 812, doi. 10.3390/cells8080812
By:
- Karvonen, Hanna;
- Barker, Harlan;
- Kaleva, Laura;
- Niininen, Wilhelmiina;
- Ungureanu, Daniela
Publication type:
Article
Interaction between ROR1 and MuSK activation complex in myogenic cells.
Published in:
FEBS Letters, 2018, v. 592, n. 3, p. 434, doi. 10.1002/1873-3468.12966
By:
- Karvonen, Hanna;
- Summala, Katja;
- Niininen, Wilhelmiina;
- Barker, Harlan R.;
- Ungureanu, Daniela
Publication type:
Article

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