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MAPK phosphatase-1 facilitates the loss of oxidative myofibers associated with obesity in mice.
Published in:
2009
By:
- Roth, Rachel J.;
- Le, Annie M.;
- Lei Zhang;
- Kahn, Mario;
- Samuel, Varman T.;
- Shulman, Gerald I.;
- Bennett, Anton M.;
- Zhang, Lei
Publication type:
journal article
Overexpression of uncoupling protein 3 in skeletal muscle protects against fat-induced insulin resistance.
Published in:
Journal of Clinical Investigation, 2007, v. 117, p. 1995, doi. 10.1172/JCI13579
By:
- Cheol Soo Choi;
- Fillmore, Jonathan J.;
- Kim, Jason K.;
- Zhen-Xiang Liu;
- Sheene Kim;
- Collier, Emily F.;
- Kulkarni, Ameya;
- Distefano, Alberto;
- Yu-Jin Hwang;
- Kahn, Mario;
- Yan Chen;
- Chunli Yu;
- Moore, Irene K.;
- Reznick, Richard M.;
- Higashimori, Takamasa;
- Shulman, Gerald I.
Publication type:
Article
Overexpression of uncoupling protein 3 in skeletal muscle protects against fat-induced insulin resistance.
Published in:
Journal of Clinical Investigation, 2007, v. 117, n. 7, p. 1995, doi. 10.1172/JCI13579
By:
- Cheol Soo Choi;
- Fillmore, Jonathan J.;
- Kim, Jason K.;
- Zhen-Xiang Liu;
- Sheene Kim;
- Collier, Emily F.;
- Kulkarni, Ameya;
- Distefano, Alberto;
- Yu-Jin Hwang;
- Kahn, Mario;
- Yan Chen;
- Chunli Yu;
- Moore, Irene K.;
- Reznick, Richard M.;
- Higashimori, Takamasa;
- Shulman, Gerald I.
Publication type:
Article
Inhibition of protein kinase Cepsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease.
Published in:
2007
By:
- Samuel, Varman T.;
- Zhen-Xiang Liu;
- Wang, Amy;
- Beddow, Sara A.;
- Geisler, John G.;
- Kahn, Mario;
- Xian-man Zhang;
- Monia, Brett P.;
- Bhanot, Sanjay;
- Shulman, Gerald I.;
- Liu, Zhen-Xiang;
- Zhang, Xian-man
Publication type:
journal article
In vivo studies on the mechanism of methylene cyclopropyl acetic acid and methylene cyclopropyl glycine-induced hypoglycemia.
Published in:
Biochemical Journal, 2018, v. 475, n. 6, p. 1063, doi. 10.1042/BCJ20180063
By:
- Yang Qiu;
- Perry, Rachel J.;
- Camporez, João-Paulo G.;
- Xian-Man Zhang;
- Kahn, Mario;
- Cline, Gary W.;
- Shulman, Gerald I.;
- Vatner, Daniel F.
Publication type:
Article
Hepatic insulin sensitivity is improved in high‐fat diet‐fed Park2 knockout mice in association with increased hepatic AMPK activation and reduced steatosis.
Published in:
Physiological Reports, 2019, v. 7, n. 21, p. N.PAG, doi. 10.14814/phy2.14281
By:
- Edmunds, Lia R.;
- Huckestein, Brydie R.;
- Kahn, Mario;
- Zhang, Dongyan;
- Chu, Yanxia;
- Zhang, Yingze;
- Wendell, Stacy G.;
- Shulman, Gerald I.;
- Jurczak, Michael J.
Publication type:
Article
Distinct subcellular localisation of intramyocellular lipids and reduced PKCε/PKCθ activity preserve muscle insulin sensitivity in exercise-trained mice.
Published in:
Diabetologia, 2023, v. 66, n. 3, p. 567, doi. 10.1007/s00125-022-05838-8
By:
- Gaspar, Rafael C.;
- Lyu, Kun;
- Hubbard, Brandon T.;
- Leitner, Brooks P.;
- Luukkonen, Panu K.;
- Hirabara, Sandro M.;
- Sakuma, Ikki;
- Nasiri, Ali;
- Zhang, Dongyan;
- Kahn, Mario;
- Cline, Gary W.;
- Pauli, José Rodrigo;
- Perry, Rachel J.;
- Petersen, Kitt F.;
- Shulman, Gerald I.
Publication type:
Article
Muscle-specific activation of Ca/calmodulin-dependent protein kinase IV increases whole-body insulin action in mice.
Published in:
Diabetologia, 2014, v. 57, n. 6, p. 1232, doi. 10.1007/s00125-014-3212-1
By:
- Lee, Hui-Young;
- Gattu, Arijeet;
- Camporez, João-Paulo;
- Kanda, Shoichi;
- Guigni, Blas;
- Kahn, Mario;
- Zhang, Dongyan;
- Galbo, Thomas;
- Birkenfeld, Andreas;
- Jornayvaz, Francois;
- Jurczak, Michael;
- Choi, Cheol;
- Yan, Zhen;
- Williams, R.;
- Shulman, Gerald;
- Samuel, Varman
Publication type:
Article
501-P: Lower Plasma Membrane Sn-1,2-Diacylglycerol Content and PKCepsilon/theta Activity Explain the Athlete's Paradox.
Published in:
Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-501-P
By:
- GASPAR, RAFAEL C.;
- LYU, KUN;
- HUBBARD, BRANDON T.;
- LEITNER, BROOKS;
- LUUKKONEN, PANU;
- HIRABARA, SANDRO;
- SAKUMA, IKKI;
- NASIRI, ALI;
- ZHANG, DONGYAN;
- KAHN, MARIO;
- CLINE, GARY;
- PAULI, JOSÉ R.;
- PERRY, RACHEL J.;
- PETERSEN, KITT;
- SHULMAN, GERALD I.
Publication type:
Article
335-OR: Lipid-Induced Insulin Resistance in the Renal Cortex Is Associated with Plasma Membrane Sn-1,2-diacylglycerol Accumulation and PKCe Translocation.
Published in:
Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-335-OR
By:
- HUBBARD, BRANDON T.;
- GASPAR, RAFAEL C.;
- ZHANG, DONGYAN;
- KAHN, MARIO;
- NASIRI, ALI;
- ZHANG, XIAN-MAN;
- CLINE, GARY;
- SHULMAN, GERALD I.
Publication type:
Article
281-OR: Endothelial Cell Cd36 Regulates Systemic Glucose and Lipid Metabolism.
Published in:
Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-281-OR
By:
- GOEDEKE, LEIGH;
- SON, NI-HUIPING;
- LAMOIA, TRACI E.;
- NASIRI, ALI;
- KAHN, MARIO;
- ZHANG, XIAN-MAN;
- CLINE, GARY;
- GOLDBERG, IRA J.;
- SHULMAN, GERALD I.
Publication type:
Article
205-OR: Hepatic Protein Kinase C-e Is Necessary and Sufficient in Mediating Lipid-Induced Hepatic Insulin Resistance.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-205-OR
By:
- LYU, KUN;
- ZHANG, DONGYAN;
- KAHN, MARIO;
- RODRIGUES, MARCOS R.S.;
- HIRABARA, SANDRO;
- LUUKKONEN, PANU;
- LEE, SEOHYUK;
- BHANOT, SANJAY;
- RINEHART, JESSE;
- BLUME, NIELS;
- RASCH, MORTEN;
- SERLIE, MIREILLE J.;
- BOGAN, JONATHAN;
- CLINE, GARY;
- SAMUEL, VARMAN;
- SHULMAN, GERALD I.
Publication type:
Article
266-OR: Plasma Membrane sn-1,2 Diacylglycerol Mediates Lipid-Induced Hepatic Insulin Resistance.
Published in:
Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-266-OR
By:
- LYU, KUN;
- ZHANG, YE;
- ZHANG, DONGYAN;
- KAHN, MARIO;
- NOZAKI, YUICHI;
- BHANOT, SANJAY;
- BOGAN, JONATHAN;
- CLINE, GARY;
- SAMUEL, VARMAN;
- SHULMAN, GERALD I.
Publication type:
Article
19-OR: Controlled-Release Mitochondrial Protonophore (CRMP) Reverses Hypertriglyceridemia and Hepatic Steatosis in Dysmetabolic Nonhuman Primates.
Published in:
Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-19-OR
By:
- GOEDEKE, LEIGH;
- ROMERAL, VALLE MONTALVO;
- BUTRICO, GINA MARIE;
- KAHN, MARIO;
- DUFOUR, SYLVIE;
- ZHANG, XIAN-MAN;
- CLINE, GARY;
- PETERSEN, KITT;
- CHNG, KEEFE;
- SHULMAN, GERALD I.
Publication type:
Article
Targeting Pyruvate Carboxylase Reduces Gluconeogenesis and Adiposity and Improves Insulin Resistance.
Published in:
Diabetes, 2013, v. 62, n. 7, p. 2183, doi. 10.2337/db12-1311
By:
- Kumashiro, Naoki;
- Beddow, Sara A.;
- Vatner, Daniel F.;
- Majumdar, Sachin K.;
- Cantley, Jennifer L.;
- Guebre-Egziabher, Fitsum;
- Fat, Ioana;
- Guigni, Blas;
- Jurczak, Michael J.;
- Birkenfeld, Andreas L.;
- Kahn, Mario;
- Perler, Bryce K.;
- Puchowicz, Michelle A.;
- Manchem, Vara Prasad;
- Bhanot, Sanjay;
- Still, Christopher D.;
- Gerhard, Glenn S.;
- Petersen, Kitt Falk;
- Cline, Gary W.;
- Shulman, Gerald I.
Publication type:
Article
Sensitivity of lipid metabolism and insulin signaling to genetic alterations in hepatic peroxisome proliferator-activated receptor-gamma coactivator-1alpha expression.
Published in:
2009
By:
- Estall JL;
- Kahn M;
- Cooper MP;
- Fisher FM;
- Wu MK;
- Laznik D;
- Qu L;
- Cohen DE;
- Shulman GI;
- Spiegelman BM;
- Estall, Jennifer L;
- Kahn, Mario;
- Cooper, Marcus P;
- Fisher, Ffolliott Martin;
- Wu, Michele K;
- Laznik, Dina;
- Qu, Lishu;
- Cohen, David E;
- Shulman, Gerald I;
- Spiegelman, Bruce M
Publication type:
journal article
Sensitivity of Lipid Metabolism and Insulin Signaling to Genetic Alterations in Hepatic Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α Expression.
Published in:
Diabetes, 2009, v. 58, n. 7, p. 1499, doi. 10.2337/db08-1571
By:
- Estall, Jennifer L.;
- Kahn, Mario;
- Cooper, Marcus P.;
- Fisher, Martin;
- Wu, Michele K.;
- Laznik, Dina;
- Qu, Lishu;
- Cohen, David E.;
- Shulman, Gerald I.;
- Spiegelman, Bruce M.
Publication type:
Article

Found: 17