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Climate Change: What Would Lincoln Do?
- Published in:
- 2017
- By:
- Publication type:
- journal article
Pathways for Oxygen Regulation and Homeostasis: The 2016 Albert Lasker Basic Medical Research Award.
- Published in:
- 2016
- By:
- Publication type:
- journal article
The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer.
- Published in:
- 2008
- By:
- Publication type:
- journal article
Molecular basis of the VHL hereditary cancer syndrome.
- Published in:
- 2002
- By:
- Publication type:
- journal article
Leveraging insights into cancer metabolism—a symposium report.
- Published in:
- Annals of the New York Academy of Sciences, 2020, v. 1462, n. 1, p. 5, doi. 10.1111/nyas.14274
- By:
- Publication type:
- Article
Suppression of tumor growth through disruption of hypoxia-inducible transcription.
- Published in:
- Nature Medicine, 2000, v. 6, n. 12, p. 1335, doi. 10.1038/82146
- By:
- Publication type:
- Article
Good COP1 or bad COP1? In vivo veritas.
- Published in:
- 2011
- By:
- Publication type:
- Opinion
HIF2alpha cooperates with RAS to promote lung tumorigenesis in mice.
- Published in:
- 2009
- By:
- Publication type:
- journal article
An intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells.
- Published in:
- EMBO Reports, 2002, v. 3, n. 2, p. 177, doi. 10.1093/embo-reports/kvf028
- By:
- Publication type:
- Article
HIF-independent synthetic lethality between CDK4/6 inhibition and VHL loss across species.
- Published in:
- Science Signaling, 2019, v. 12, n. 601, p. 1, doi. 10.1126/scisignal.aay0482
- By:
- Publication type:
- Article
Bioluminescent imaging of Cdk2 inhibition in vivo.
- Published in:
- Nature Medicine, 2004, v. 10, n. 6, p. 643, doi. 10.1038/nm1047
- By:
- Publication type:
- Article
A common polymorphism acts as an intragenic modifier of mutant p53 behaviour.
- Published in:
- Nature Genetics, 2000, v. 25, n. 1, p. 47, doi. 10.1038/75586
- By:
- Publication type:
- Article
New cancer targets emerging from studies of the Von Hippel-Lindau tumor suppressor protein Kaelin New cancer targets.
- Published in:
- Annals of the New York Academy of Sciences, 2010, v. 1210, n. 1, p. 1, doi. 10.1111/j.1749-6632.2010.05781.x
- By:
- Publication type:
- Article
Alterations in G1/S Cell-Cycle Control Contributing to Carcinogenesis.
- Published in:
- Annals of the New York Academy of Sciences, 1997, v. 833, n. 1, p. 29, doi. 10.1111/j.1749-6632.1997.tb48589.x
- By:
- Publication type:
- Article
The emerging p53 gene family.
- Published in:
- 1999
- By:
- Publication type:
- journal article
EglN2 associates with the NRF1-PGC1α complex and controls mitochondrial function in breast cancer.
- Published in:
- EMBO Journal, 2015, v. 34, n. 23, p. 2953, doi. 10.15252/embj.201591437
- By:
- Publication type:
- Article
Failure to prolyl hydroxylate hypoxia-inducible factor α phenocopies VHL inactivation in vivo.
- Published in:
- EMBO Journal, 2006, v. 25, n. 19, p. 4650, doi. 10.1038/sj.emboj.7601300
- By:
- Publication type:
- Article
Q&A: Cancer: Clues from cell metabolism.
- Published in:
- 2010
- By:
- Publication type:
- Question & Answer
Cell biology: Divining cancer cell weaknesses.
- Published in:
- Nature, 2006, v. 441, n. 7089, p. 32, doi. 10.1038/441032a
- By:
- Publication type:
- Article
VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400.
- Published in:
- Nature Cell Biology, 2008, v. 10, n. 3, p. 361, doi. 10.1038/ncb1699
- By:
- Publication type:
- Article
Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit.
- Published in:
- Nature Cell Biology, 2007, v. 9, n. 2, p. 225, doi. 10.1038/ncb1532
- By:
- Publication type:
- Article
Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel?Lindau protein.
- Published in:
- Nature Cell Biology, 2000, v. 2, n. 7, p. 423, doi. 10.1038/35017054
- By:
- Publication type:
- Article
Cyclin D1 suppresses retinoblastoma protein-mediated inhibition of TAF<sub>II</sub>250 kinase activity.
- Published in:
- Oncogene, 2000, v. 19, n. 50, p. 5703, doi. 10.1038/sj.onc.1203966
- By:
- Publication type:
- Article
The p53 gene family.
- Published in:
- Oncogene, 1999, v. 18, n. 53, p. 7701, doi. 10.1038/sj.onc.1202955
- By:
- Publication type:
- Article
Functions of the retinoblastoma protein.
- Published in:
- BioEssays, 1999, v. 21, n. 11, p. 950, doi. 10.1002/(SICI)1521-1878(199911)21:11<950::AID-BIES7>3.0.CO;2-D
- By:
- Publication type:
- Article
THE JEREMIAH METZGER LECTURE: VON HIPPEL-LINDAU DISEASE: INSIGHTS INTO OXYGEN SENSING, CANCER AND DRUGGING THE UNDRUGGABLE.
- Published in:
- Transactions of the American Clinical & Climatological Association, 2022, v. 132, p. 170
- By:
- Publication type:
- Article
THE VHL TUMOR SUPPRESSOR GENE: INSIGHTS INTO OXYGEN SENSING AND CANCER.
- Published in:
- Transactions of the American Clinical & Climatological Association, 2017, v. 128, p. 298
- By:
- Publication type:
- Article
Slaying RAS with a synthetic lethal weapon.
- Published in:
- Cell Research, 2010, v. 20, n. 2, p. 119, doi. 10.1038/cr.2010.16
- By:
- Publication type:
- Article
HIF activation causes synthetic lethality between the VHL tumor suppressor and the EZH1 histone methyltransferase.
- Published in:
- Science Translational Medicine, 2017, v. 9, n. 398, p. 1, doi. 10.1126/scitranslmed.aal5272
- By:
- Publication type:
- Article
Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex.
- Published in:
- Nature, 2004, v. 428, n. 6979, p. 194, doi. 10.1038/nature02381
- By:
- Publication type:
- Article
Role for the p53 homologue p73 in E2F-1-induced apoptosis.
- Published in:
- Nature, 2000, v. 407, n. 6804, p. 645, doi. 10.1038/35036614
- By:
- Publication type:
- Article
A common E2F-1 and p73 pathway mediates cell death induced by TCR activation.
- Published in:
- Nature, 2000, v. 407, n. 6804, p. 642, doi. 10.1038/35036608
- By:
- Publication type:
- Article
Inhibition of HIF2α Is Sufficient to Suppress pVHL-Defective Tumor Growth.
- Published in:
- PLoS Biology, 2003, v. 1, n. 12, p. 1, doi. 10.1371/journal.pbio.0000083
- By:
- Publication type:
- Article
Inhibition of HIF2 a Is Sufficient to Suppress pVHL-Defective Tumor Growth.
- Published in:
- PLoS Biology, 2003, v. 1, n. 3, p. 339, doi. 10.1371/journal.pbio.0000083
- By:
- Publication type:
- Article
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation.
- Published in:
- Nature, 2012, v. 483, n. 7390, p. 484, doi. 10.1038/nature10898
- By:
- Publication type:
- Article
Treatment of kidney cancer: insights provided by the VHL tumor-suppressor protein.
- Published in:
- 2009
- By:
- Publication type:
- journal article
Treatment of Kidney Cancer.
- Published in:
- Cancer (0008543X), 2009, v. 115, n. 10, p. 2262, doi. 10.1002/cncr.24232
- By:
- Publication type:
- Article
Innovations and Challenges in Renal Cancer: Summary Statement From the Third Cambridge Conference.
- Published in:
- 2009
- By:
- Publication type:
- Proceeding
Erlotinib therapy for central nervous system hemangioblastomatosis associated with von Hippel-Lindau disease: a case report.
- Published in:
- 2011
- By:
- Publication type:
- Report
The INDIGO trial: Precision medicine finally comes to glioma.
- Published in:
- 2023
- By:
- Publication type:
- Editorial
von Hippel-Lindau protein mutants linked to type 2C VHL disease preserve the ability to downregulate HIF.
- Published in:
- Human Molecular Genetics, 2001, v. 10, n. 10, p. 1019, doi. 10.1093/hmg/10.10.1019
- By:
- Publication type:
- Article
Recent insights into the molecular pathogenesis of pheochromocytoma and paraganglioma.
- Published in:
- Endocrine Pathology, 2006, v. 17, n. 2, p. 97, doi. 10.1385/EP:17:2:97
- By:
- Publication type:
- Article
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage.
- Published in:
- Nature, 1999, v. 399, n. 6738, p. 806, doi. 10.1038/21690
- By:
- Publication type:
- Article
Many vessels, faulty gene.
- Published in:
- Nature, 1999, v. 399, n. 6733, p. 203, doi. 10.1038/20309
- By:
- Publication type:
- Article
Mouse Reporter Strain for Noninvasive Bioluminescent Imaging of Cells that Have Undergone Cre-Mediated Recombination.
- Published in:
- Molecular Imaging, 2003, v. 2, n. 4, p. 297, doi. 10.1162/153535003322750637
- By:
- Publication type:
- Article
The Concept of Synthetic Lethality in the Context of Anticancer Therapy.
- Published in:
- Nature Reviews Cancer, 2005, v. 5, n. 9, p. 689, doi. 10.1038/nrc1691
- By:
- Publication type:
- Article
The cdk/pRB/E2F pathway in human cancer.
- Published in:
- Kidney International, 1999, v. 56, n. 4, p. 1183, doi. 10.1046/j.1523-1755.1999.0560041183.x
- By:
- Publication type:
- Article
Regulation of vascular endothelial growth factor by hypoxia and its modulation by the von Hippel-Lindau tumor suppressor gene.
- Published in:
- Kidney International, 1997, v. 51, n. 2, p. 575, doi. 10.1038/ki.1997.82
- By:
- Publication type:
- Article