Found: 26
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Norepinephrine transporter occupancy in the human brain after oral administration of quetiapine XR.
- Published in:
- International Journal of Neuropsychopharmacology, 2013, v. 16, n. 10, p. 2235, doi. 10.1017/S1461145713000680
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- Publication type:
- Article
Distribution of Zolmitriptan into the CNS in Healthy Volunteers: A Positron Emission Tomography Study.
- Published in:
- Drugs in R&D, 2005, v. 6, n. 3, p. 139, doi. 10.2165/00126839-200506030-00002
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- Publication type:
- Article
Confounding factors in exposure–response analyses and mitigation strategies for monoclonal antibodies in oncology.
- Published in:
- British Journal of Clinical Pharmacology, 2021, v. 87, n. 6, p. 2493, doi. 10.1111/bcp.14662
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- Publication type:
- Article
Estimation of drug receptor occupancy when non-displaceable binding differs between brain regions - extending the simplified reference tissue model.
- Published in:
- British Journal of Clinical Pharmacology, 2015, v. 80, n. 1, p. 116, doi. 10.1111/bcp.12558
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- Publication type:
- Article
Dose-dependent binding of AZD3783 to brain 5-HT receptors in non-human primates and human subjects: a positron emission tomography study with [C]AZ10419369.
- Published in:
- Psychopharmacology, 2011, v. 213, n. 2/3, p. 533, doi. 10.1007/s00213-011-2165-z
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- Publication type:
- Article
Model‐Informed Therapeutic Dose Optimization Strategies for Antibody–Drug Conjugates in Oncology: What Can We Learn From US Food and Drug Administration–Approved Antibody–Drug Conjugates?
- Published in:
- Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 5, p. 1216, doi. 10.1002/cpt.2278
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- Publication type:
- Article
Correction to: Population pharmacokinetic and exploratory exposure–response analysis of the fixed-dose combination of pertuzumab and trastuzumab for subcutaneous injection in patients with HER2-positive early breast cancer in the FeDeriCa study.
- Published in:
- 2022
- By:
- Publication type:
- Correction Notice
Population pharmacokinetic and exploratory exposure–response analysis of the fixed-dose combination of pertuzumab and trastuzumab for subcutaneous injection in patients with HER2-positive early breast cancer in the FeDeriCa study.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2021, v. 88, n. 3, p. 499, doi. 10.1007/s00280-021-04296-0
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- Publication type:
- Article
Pharmacokinetic and exploratory exposure-response analysis of pertuzumab in patients with operable HER2-positive early breast cancer in the APHINITY study.
- Published in:
- 2019
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- Publication type:
- journal article
gPKPDviz: A flexible R shiny tool for pharmacokinetic/pharmacodynamic simulations using mrgsolve.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2024, v. 13, n. 3, p. 341, doi. 10.1002/psp4.13096
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- Publication type:
- Article
Simulation‐based evaluation of personalized dosing approaches for anti‐FGFR/KLB bispecific antibody fazpilodemab.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2024, v. 13, n. 4, p. 544, doi. 10.1002/psp4.13111
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- Publication type:
- Article
A New Method to Model and Predict Progression Free Survival Based on Tumor Growth Dynamics.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2020, v. 9, n. 3, p. 177, doi. 10.1002/psp4.12499
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- Publication type:
- Article
Analysis of Longitudinal‐Ordered Categorical Data for Muscle Spasm Adverse Event of Vismodegib: Comparison Between Different Pharmacometric Models.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2020, v. 9, n. 2, p. 96, doi. 10.1002/psp4.12487
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- Publication type:
- Article
Time‐to‐Event Modeling of Peripheral Neuropathy: Platform Analysis of Eight Valine‐Citrulline‐Monomethylauristatin E Antibody–Drug Conjugates.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2019, v. 8, n. 8, p. 606, doi. 10.1002/psp4.12442
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- Publication type:
- Article
Pharmacokinetic-Pharmacodynamic Modeling of Fostamatinib Efficacy on ACR20 to Support Dose Selection in Patients With Rheumatoid Arthritis (RA)
- Published in:
- 2015
- By:
- Publication type:
- Journal Article
Pharmacokinetic-Pharmacodynamic Modeling of Fostamatinib Efficacy on ACR20 to Support Dose Selection in Patients With Rheumatoid Arthritis (RA).
- Published in:
- Journal of Clinical Pharmacology, 2015, v. 55, n. 3, p. 328, doi. 10.1002/jcph.406
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- Publication type:
- Article
Support to early clinical decisions in drug development and personalised medicine with checkpoint inhibitors using dynamic biomarker-overall survival models.
- Published in:
- British Journal of Cancer, 2023, v. 129, n. 9, p. 1383, doi. 10.1038/s41416-023-02190-5
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- Publication type:
- Article
A longitudinal model for the Mayo Clinical Score and its sub-components in patients with ulcerative colitis.
- Published in:
- Journal of Pharmacokinetics & Pharmacodynamics, 2022, v. 49, n. 2, p. 179, doi. 10.1007/s10928-021-09789-2
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- Publication type:
- Article
Platform model describing pharmacokinetic properties of vc-MMAE antibody-drug conjugates.
- Published in:
- Journal of Pharmacokinetics & Pharmacodynamics, 2017, v. 44, n. 6, p. 537, doi. 10.1007/s10928-017-9544-y
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- Publication type:
- Article
Improved precision of exposure-response relationships by optimal dose-selection. Examples from studies of receptor occupancy using PET and dose finding for neuropathic pain treatment.
- Published in:
- Journal of Pharmacokinetics & Pharmacodynamics, 2015, v. 42, n. 3, p. 211, doi. 10.1007/s10928-015-9410-8
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- Publication type:
- Article
Population Pharmacokinetics of Ranibizumab Delivered via the Port Delivery System Implanted in the Eye in Patients with Neovascular Age‐Related Macular Degeneration.
- Published in:
- Journal of Clinical Pharmacology, 2023, v. 63, n. 11, p. 1210, doi. 10.1002/jcph.2290
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- Publication type:
- Article
Impact of Physiologically Based Pharmacokinetics, Population Pharmacokinetics and Pharmacokinetics/Pharmacodynamics in the Development of Antibody‐Drug Conjugates.
- Published in:
- Journal of Clinical Pharmacology, 2020, v. 60, p. S105, doi. 10.1002/jcph.1720
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- Publication type:
- Article
Development of a Subcutaneous Fixed‐Dose Combination of Pertuzumab and Trastuzumab: Results From the Phase Ib Dose‐Finding Study.
- Published in:
- Journal of Clinical Pharmacology, 2019, v. 59, n. 5, p. 702, doi. 10.1002/jcph.1362
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- Publication type:
- Article
A disease model predicting placebo response and remission status of patients with ulcerative colitis using modified Mayo score.
- Published in:
- CTS: Clinical & Translational Science, 2023, v. 16, n. 11, p. 2310, doi. 10.1111/cts.13632
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- Publication type:
- Article
Pharmacokinetics of the Port Delivery System with Ranibizumab in the Ladder Phase 2 Trial for Neovascular Age-Related Macular Degeneration.
- Published in:
- Ophthalmology & Therapy, 2022, v. 11, n. 5, p. 1705, doi. 10.1007/s40123-022-00532-9
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- Publication type:
- Article
Autoradiographic Mapping of 5-HT<sub>1B/1D</sub> Binding Sites in the Rhesus Monkey Brain Using [carbonyl-<sup>11</sup>C]zolmitriptan.
- Published in:
- International Journal of Molecular Imaging, 2011, p. 1, doi. 10.1155/2011/694179
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- Publication type:
- Article