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Alternating Hemiplegia of Childhood-Related Neural and Behavioural Phenotypes in Na+,K+-ATPase α3 Missense Mutant Mice.
Published in:
PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0060141
By:
- Kirshenbaum, Greer S.;
- Dawson, Neil;
- Mullins, Jonathan G. L.;
- Johnston, Tom H.;
- Drinkhill, Mark J.;
- Edwards, Ian J.;
- Fox, Susan H.;
- Pratt, Judith A.;
- Brotchie, Jonathan M.;
- Roder, John C.;
- Clapcote, Steven J.
Publication type:
Article
The Monoamine Re-Uptake Inhibitor UWA-101 Improves Motor Fluctuations in the MPTP-Lesioned Common Marmoset.
Published in:
PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0045587
By:
- Huot, Philippe;
- Johnston, Tom H.;
- Gandy, Michael N.;
- Reyes, M. Gabriela;
- Fox, Susan H.;
- Piggott, Matthew J.;
- Brotchie, Jonathan M.;
- Sgambato-Faure, Veronique
Publication type:
Article
Progressive Neurodegeneration or Endogenous Compensation in an Animal Model of Parkinson's Disease Produced by Decreasing Doses of Alpha-Synuclein.
Published in:
PLoS ONE, 2011, v. 6, n. 3, p. 1, doi. 10.1371/journal.pone.0017698
By:
- Koprich, James B.;
- Johnston, Tom H.;
- Huot, Philippe;
- Reyes, M. Gabriela;
- Espinosa, Maria;
- Brotchie, Jonathan M.
Publication type:
Article
Receptor-activity modifying protein 1 expression is increased in the striatum following repeated L-DOPA administration in a 6-hydroxydopamine lesioned rat model of Parkinson's disease.
Published in:
Synapse, 2008, v. 62, n. 4, p. 310, doi. 10.1002/syn.20481
By:
- Lee, Joohyung;
- Gomez-Ramirez, Jordi;
- Johnston, Tom H.;
- Visanji, Naomi;
- Brotchie, Jonathan M.
Publication type:
Article
Toward in vivo proof of binding of 18F-labeled inhibitor [18F]TRACK to peripheral tropomyosin receptor kinases.
Published in:
EJNMMI Research, 2022, v. 12, n. 1, p. 1, doi. 10.1186/s13550-022-00915-w
By:
- Wuest, Melinda;
- Bailey, Justin J.;
- Dufour, Jennifer;
- Glubrecht, Darryl;
- Omana, Vanessa;
- Johnston, Tom H.;
- Brotchie, Jonathan M.;
- Schirrmacher, Ralf
Publication type:
Article
A novel MDMA analogue, UWA-101, that lacks psychoactivity and cytotoxicity, enhances L-DOPA benefit in parkinsonian primates.
Published in:
FASEB Journal, 2012, v. 26, n. 5, p. 2154, doi. 10.1096/fj.11-195016
By:
- Johnston, Tom H.;
- Millar, Zak;
- Huot, Philippe;
- Wagg, Keith;
- Thiele, Sherri;
- Salomonczyk, Danielle;
- Yong-Kee, Christopher J.;
- Gandy, Michael N.;
- McIldowie, Matthew;
- Lewis, Katie D.;
- Gomez-Ramirez, Jordi;
- Joohyung Lee;
- Fox, Susan H.;
- Martin-Iverson, Mathew;
- Nash, Joanne E.;
- Piggott, Matthew J.;
- Brotchie, Jonathan M.
Publication type:
Article
Pioglitazone may impair L-DOPA anti-parkinsonian efficacy in the MPTP-lesioned macaque: Results of a pilot study.
Published in:
Synapse, 2015, v. 69, n. 3, p. 99, doi. 10.1002/syn.21801
By:
- Huot, Philippe;
- Johnston, Tom H.;
- Fox, Susan H.;
- Brotchie, Jonathan M.
Publication type:
Article
Towards a Non-Human Primate Model of Alpha-Synucleinopathy for Development of Therapeutics for Parkinson’s Disease: Optimization of AAV1/2 Delivery Parameters to Drive Sustained Expression of Alpha Synuclein and Dopaminergic Degeneration in Macaque.
Published in:
PLoS ONE, 2016, v. 11, n. 11, p. 1, doi. 10.1371/journal.pone.0167235
By:
- Koprich, James B.;
- Johnston, Tom H.;
- Reyes, Gabriela;
- Omana, Vanessa;
- Brotchie, Jonathan M.
Publication type:
Article
Pridopidine, a clinic-ready compound, reduces 3,4-dihydroxyphenylalanine-induced dyskinesia in Parkinsonian macaques.
Published in:
2019
By:
- Johnston, Tom H.;
- Geva, Michal;
- Steiner, Lilach;
- Orbach, Aric;
- Papapetropoulos, Spyros;
- Savola, Juha‐Matti;
- Reynolds, Ian J.;
- Ravenscroft, Paula;
- Hill, Michael;
- Fox, Susan H.;
- Brotchie, Jonathan M.;
- Laufer, Ralph;
- Hayden, Michael R.;
- Savola, Juha-Matti
Publication type:
journal article
Use of catechol- O-methyltransferase inhibition to minimize L-3,4-dihydroxyphenylalanine-induced dyskinesia in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque.
Published in:
European Journal of Neuroscience, 2013, v. 37, n. 5, p. 831, doi. 10.1111/ejn.12093
By:
- Huot, Philippe;
- Johnston, Tom H.;
- Snoeren, Tessa;
- Koprich, James B.;
- Hill, Michael P.;
- Fox, Susan H.;
- Brotchie, Jonathan M.
Publication type:
Article
MOLECULAR NEURODEGENERATION.
Published in:
Molecular Neurodegeneration, 2010, v. 5, p. 43, doi. 10.1186/1750-1326-5-43
By:
- Koprich, James B.;
- Johnston, Tom H.;
- Reyes, M. Gabriela;
- Xuan Sun;
- Brotchie, Jonathan M.
Publication type:
Article
Reproducibility of a Parkinsonism-related metabolic brain network in non-human primates: A descriptive pilot study with FDG PET.
Published in:
2015
By:
- Ma, Yilong;
- Johnston, Tom H.;
- Peng, Shichun;
- Zuo, Chuantao;
- Koprich, James B.;
- Fox, Susan H.;
- Guan, Yihui;
- Eidelberg, David;
- Brotchie, Jonathan M.
Publication type:
journal article
Rotigotine polyoxazoline conjugate SER-214 provides robust and sustained antiparkinsonian benefit.
Published in:
Movement Disorders, 2013, v. 28, n. 12, p. 1675, doi. 10.1002/mds.25625
By:
- Eskow Jaunarajs, Karen L.;
- Standaert, David G.;
- Viegas, Tacey X.;
- Bentley, Michael D.;
- Fang, Zhihao;
- Dizman, Bekir;
- Yoon, Kunsang;
- Weimer, Rebecca;
- Ravenscroft, Paula;
- Johnston, Tom H.;
- Hill, Michael P.;
- Brotchie, Jonathan M.;
- Moreadith, Randall W.
Publication type:
Article
A critique of available scales and presentation of the non-human primate dyskinesia rating scale.
Published in:
Movement Disorders, 2012, v. 27, n. 11, p. 1373, doi. 10.1002/mds.25133
By:
- Fox, Susan H.;
- Johnston, Tom H.;
- Li, Qin;
- Brotchie, Jonathan;
- Bezard, Erwan
Publication type:
Article
Increased levels of 5-HT1A receptor binding in ventral visual pathways in Parkinson's disease.
Published in:
2012
By:
- Huot P;
- Johnston TH;
- Visanji NP;
- Darr T;
- Pires D;
- Hazrati LN;
- Brotchie JM;
- Fox SH;
- Huot, Philippe;
- Johnston, Tom H;
- Visanji, Naomi P;
- Darr, Tayyeba;
- Pires, Donna;
- Hazrati, Lili-Naz;
- Brotchie, Jonathan M;
- Fox, Susan H
Publication type:
journal article
Increased levels of 5-HT1A receptor binding in ventral visual pathways in Parkinson's disease.
Published in:
Movement Disorders, 2012, v. 27, n. 6, p. 735, doi. 10.1002/mds.24964
By:
- Huot, Philippe;
- Johnston, Tom H.;
- Visanji, Naomi P.;
- Darr, Tayyeba;
- Pires, Donna;
- Hazrati, Lili-Naz;
- Brotchie, Jonathan M.;
- Fox, Susan H.
Publication type:
Article
The selective mu-opioid receptor antagonist adl5510 reduces levodopa-induced dyskinesia without affecting antiparkinsonian action in mptp-lesioned macaque model of Parkinson's disease.
Published in:
Movement Disorders, 2011, v. 26, n. 7, p. 1225, doi. 10.1002/mds.23631
By:
- Koprich, James B.;
- Fox, Susan H.;
- Johnston, Tom H.;
- Goodman, Allan;
- Le Bourdonnec, Bertrand;
- Dolle, Roland E.;
- DeHaven, Robert N.;
- DeHaven-Hudkins, Diane L.;
- Little, Patrick J.;
- Brotchie, Jonathan M.
Publication type:
Article
The α2 adrenergic antagonist fipamezole improves quality of levodopa action in Parkinsonian primates.
Published in:
Movement Disorders, 2010, v. 25, n. 13, p. 2084, doi. 10.1002/mds.23172
By:
- Johnston, Tom H.;
- Fox, Susan H.;
- Piggott, Matthew J.;
- Savola, Juha-Matti;
- Brotchie, Jonathan M.
Publication type:
Article
Increased 5-HT2A receptors in the temporal cortex of parkinsonian patients with visual hallucinations.
Published in:
Movement Disorders, 2010, v. 25, n. 10, p. 1399, doi. 10.1002/mds.23083
By:
- Huot, Philippe;
- Johnston, Tom H.;
- Darr, Tayyeba;
- Hazrati, Lili-Naz;
- Visanji, Naomi P.;
- Pires, Donna;
- Brotchie, Jonathan M.;
- Fox, Susan H.
Publication type:
Article
Effect of histamine H2 receptor antagonism on levodopa-induced dyskinesia in the MPTP-macaque model of Parkinson's disease.
Published in:
Movement Disorders, 2010, v. 25, n. 10, p. 1379, doi. 10.1002/mds.23069
By:
- Johnston, Tom H.;
- van der Meij, Anne;
- Brotchie, Jonathan M.;
- Fox, Susan H.
Publication type:
Article
The nociceptin/orphanin FQ (NOP) receptor antagonist J-113397 enhances the effects of levodopa in the MPTP-lesioned nonhuman primate model of Parkinson's disease.
Published in:
Movement Disorders, 2008, v. 23, n. 13, p. 1922, doi. 10.1002/mds.22086
By:
- Visanji, Naomi P.;
- de Bie, Rob M.A.;
- Johnston, Tom H.;
- McCreary, Andrew C.;
- Brotchie, Jonathan M.;
- Fox, Susan H.
Publication type:
Article
Pharmacological characterization of psychosis-like behavior in the MPTP-lesioned nonhuman primate model of Parkinson's disease.
Published in:
Movement Disorders, 2006, v. 21, n. 11, p. 1879, doi. 10.1002/mds.21073
By:
- Visanji, Naomi P.;
- Gomez-Ramirez, Jordi;
- Johnston, Tom H.;
- Pires, Donna;
- Voon, Valerie;
- Brotchie, Jonathan M.;
- Fox, Susan H.
Publication type:
Article
Histamine H3 receptor agonists reduce.
Published in:
Movement Disorders, 2006, v. 21, n. 6, p. 839, doi. 10.1002/mds.20828
By:
- Gomez-Ramirez, Jordi;
- Johnston, Tom H.;
- Visanji, Naomi P.;
- Fox, Susan H.;
- Brotchie, Jonathan M.
Publication type:
Article
Characterization of 3,4-Methylenedioxymethamphetamine (MDMA) Enantiomers In Vitro and in the MPTP-Lesioned Primate: R-MDMA Reduces Severity of Dyskinesia, Whereas S-MDMA Extends Duration of ON-Time.
Published in:
Journal of Neuroscience, 2011, v. 31, n. 19, p. 7190, doi. 10.1523/JNEUROSCI.1171-11.2011
By:
- Huot, Philippe;
- Johnston, Tom H.;
- Lewis, Katie D.;
- Koprich, James B.;
- Reyes, M. Gabriela;
- Fox, Susan H.;
- Piggott, Matthew J.;
- Brotchie, Jonathan M.
Publication type:
Article

Found: 24

Alternating Hemiplegia of Childhood-Related Neural and Behavioural Phenotypes in Na<sup>+</sup>,K<sup>+</sup>-ATPase α3 Missense Mutant Mice.

The Monoamine Re-Uptake Inhibitor UWA-101 Improves Motor Fluctuations in the MPTP-Lesioned Common Marmoset.

Progressive Neurodegeneration or Endogenous Compensation in an Animal Model of Parkinson's Disease Produced by Decreasing Doses of Alpha-Synuclein.

Receptor-activity modifying protein 1 expression is increased in the striatum following repeated L-DOPA administration in a 6-hydroxydopamine lesioned rat model of Parkinson's disease.

Toward in vivo proof of binding of <sup>18</sup>F-labeled inhibitor [<sup>18</sup>F]TRACK to peripheral tropomyosin receptor kinases.

A novel MDMA analogue, UWA-101, that lacks psychoactivity and cytotoxicity, enhances L-DOPA benefit in parkinsonian primates.

Pioglitazone may impair L-DOPA anti-parkinsonian efficacy in the MPTP-lesioned macaque: Results of a pilot study.

Towards a Non-Human Primate Model of Alpha-Synucleinopathy for Development of Therapeutics for Parkinson’s Disease: Optimization of AAV1/2 Delivery Parameters to Drive Sustained Expression of Alpha Synuclein and Dopaminergic Degeneration in Macaque.

Pridopidine, a clinic-ready compound, reduces 3,4-dihydroxyphenylalanine-induced dyskinesia in Parkinsonian macaques.

Use of catechol- O-methyltransferase inhibition to minimize L-3,4-dihydroxyphenylalanine-induced dyskinesia in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque.

MOLECULAR NEURODEGENERATION.

Reproducibility of a Parkinsonism-related metabolic brain network in non-human primates: A descriptive pilot study with FDG PET.

Rotigotine polyoxazoline conjugate SER-214 provides robust and sustained antiparkinsonian benefit.

A critique of available scales and presentation of the non-human primate dyskinesia rating scale.

Increased levels of 5-HT1A receptor binding in ventral visual pathways in Parkinson's disease.

Increased levels of 5-HT<sub>1A</sub> receptor binding in ventral visual pathways in Parkinson's disease.

The selective mu-opioid receptor antagonist adl5510 reduces levodopa-induced dyskinesia without affecting antiparkinsonian action in mptp-lesioned macaque model of Parkinson's disease.

The α<sub>2</sub> adrenergic antagonist fipamezole improves quality of levodopa action in Parkinsonian primates.

Increased 5-HT<sub>2A</sub> receptors in the temporal cortex of parkinsonian patients with visual hallucinations.

Effect of histamine H<sub>2</sub> receptor antagonism on levodopa-induced dyskinesia in the MPTP-macaque model of Parkinson's disease.

The nociceptin/orphanin FQ (NOP) receptor antagonist J-113397 enhances the effects of levodopa in the MPTP-lesioned nonhuman primate model of Parkinson's disease.

Pharmacological characterization of psychosis-like behavior in the MPTP-lesioned nonhuman primate model of Parkinson's disease.

Histamine H3 receptor agonists reduce.

Characterization of 3,4-Methylenedioxymethamphetamine (MDMA) Enantiomers In Vitro and in the MPTP-Lesioned Primate: R-MDMA Reduces Severity of Dyskinesia, Whereas S-MDMA Extends Duration of ON-Time.