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Asparagine synthetase and G‐protein coupled estrogen receptor are critical responders to nutrient supply in KRAS mutant colorectal cancer.
Published in:
International Journal of Cancer, 2025, v. 156, n. 1, p. 52, doi. 10.1002/ijc.35104
By:
- Lu, Lingeng;
- Zhang, Qian;
- Aladelokun, Oladimeji;
- Berardi, Domenica;
- Shen, Xinyi;
- Marin, Audrey;
- Garcia‐Milian, Rolando;
- Roper, Jatin;
- Khan, Sajid A.;
- Johnson, Caroline H.
Publication type:
Article
Beyond genomics: understanding exposotypes through metabolomics.
Published in:
Human Genomics, 2018, v. 12, p. 1, doi. 10.1186/s40246-018-0134-x
By:
- Rattray, Nicholas J. W.;
- Deziel, Nicole C.;
- Wallach, Joshua D.;
- Khan, Sajid A.;
- Vasiliou, Vasilis;
- Ioannidis, John P. A.;
- Johnson, Caroline H.
Publication type:
Article
Yale school of public health symposium on lifetime exposures and human health: the exposome; summary and future reflections.
Published in:
Human Genomics, 2017, v. 11, p. 1, doi. 10.1186/s40246-017-0128-0
By:
- Johnson, Caroline H.;
- Athersuch, Toby J.;
- Collman, Gwen W.;
- Dhungana, Suraj;
- Grant, David F.;
- Jones, Dean P.;
- Patel, Chirag J.;
- Vasiliou, Vasilis
Publication type:
Article
Yale School of Public Health Symposium on tissue imaging mass spectrometry: illuminating phenotypic heterogeneity and drug disposition at the molecular level.
Published in:
Human Genomics, 2018, v. 12, p. 1, doi. 10.1186/s40246-018-0142-x
By:
- Charkoftaki, Georgia;
- Rattray, Nicholas J. W.;
- Andrén, Per E.;
- Caprioli, Richard M.;
- Castellino, Steve;
- Duncan, Mark W.;
- Goodwin, Richard J. A.;
- Schey, Kevin L.;
- Shahidi-Latham, Sheerin K.;
- Veselkov, Kirill A.;
- Johnson, Caroline H.;
- Vasiliou, Vasilis
Publication type:
Article
TidyMass an object-oriented reproducible analysis framework for LC–MS data.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32155-w
By:
- Shen, Xiaotao;
- Yan, Hong;
- Wang, Chuchu;
- Gao, Peng;
- Johnson, Caroline H.;
- Snyder, Michael P.
Publication type:
Article
Growth characteristics of HCT116 xenografts lacking asparagine synthetase vary according to sex.
Published in:
Human Genomics, 2024, v. 18, n. 1, p. 1, doi. 10.1186/s40246-024-00635-3
By:
- Aladelokun, Oladimeji;
- Lu, Lingeng;
- Zheng, Jie;
- Yan, Hong;
- Jain, Abhishek;
- Gibson, Joanna;
- Khan, Sajid A.;
- Johnson, Caroline H.
Publication type:
Article
Asparagine Metabolism in Tumors Is Linked to Poor Survival in Females with Colorectal Cancer: A Cohort Study.
Published in:
Metabolites (2218-1989), 2022, v. 12, n. 2, p. N.PAG, doi. 10.3390/metabo12020164
By:
- Shen, Xinyi;
- Cai, Yuping;
- Lu, Lingeng;
- Huang, Huang;
- Yan, Hong;
- Paty, Philip B.;
- Muca, Engjel;
- Ahuja, Nita;
- Zhang, Yawei;
- Johnson, Caroline H.;
- Khan, Sajid A.
Publication type:
Article
Tumor Tissue-Specific Biomarkers of Colorectal Cancer by Anatomic Location and Stage.
Published in:
Metabolites (2218-1989), 2020, v. 10, n. 6, p. 257, doi. 10.3390/metabo10060257
By:
- Cai, Yuping;
- Rattray, Nicholas J. W.;
- Zhang, Qian;
- Mironova, Varvara;
- Santos-Neto, Alvaro;
- Muca, Engjel;
- Vollmar, Ana K. Rosen;
- Hsu, Kuo-Shun;
- Rattray, Zahra;
- Cross, Justin R.;
- Zhang, Yawei;
- Paty, Philip B.;
- Khan, Sajid A.;
- Johnson, Caroline H.
Publication type:
Article
Normalizing Untargeted Periconceptional Urinary Metabolomics Data: A Comparison of Approaches.
Published in:
Metabolites (2218-1989), 2019, v. 9, n. 10, p. 198, doi. 10.3390/metabo9100198
By:
- Rosen Vollmar, Ana K.;
- Rattray, Nicholas J. W.;
- Cai, Yuping;
- Santos-Neto, Álvaro J.;
- Deziel, Nicole C.;
- Jukic, Anne Marie Z.;
- Johnson, Caroline H.
Publication type:
Article
Palbociclib and Fulvestrant Act in Synergy to Modulate Central Carbon Metabolism in Breast Cancer Cells.
Published in:
Metabolites (2218-1989), 2019, v. 9, n. 1, p. 7, doi. 10.3390/metabo9010007
By:
- Warth, Benedikt;
- Palermo, Amelia;
- Rattray, Nicholas J.W.;
- Lee, Nathan V.;
- Zhu, Zhou;
- Hoang, Linh T.;
- Cai, Yuping;
- Mazurek, Anthony;
- Dann, Stephen;
- VanArsdale, Todd;
- Fantin, Valeria R.;
- Shields, David;
- Siuzdak, Gary;
- Johnson, Caroline H.
Publication type:
Article
Metabolomic data streaming for biology-dependent data acquisition.
Published in:
Nature Biotechnology, 2014, v. 32, n. 6, p. 524, doi. 10.1038/nbt.2927
By:
- Rinehart, Duane;
- Johnson, Caroline H;
- Nguyen, Thomas;
- Ivanisevic, Julijana;
- Benton, H Paul;
- Lloyd, Jessica;
- Arkin, Adam P;
- Deutschbauer, Adam M;
- Patti, Gary J;
- Siuzdak, Gary
Publication type:
Article
Targeted Metabolomics of Serum Acylcarnitines Evaluates Hepatoprotective Effect of Wuzhi Tablet (Schisandra sphenanthera Extract) against Acute Acetaminophen Toxicity.
Published in:
Evidence-based Complementary & Alternative Medicine (eCAM), 2013, v. 2013, p. 1, doi. 10.1155/2013/985257
By:
- Huichang Bi;
- Fei Li;
- Krausz, Kristopher W.;
- Aijuan Qu;
- Johnson, Caroline H.;
- Gonzalez, Frank J.
Publication type:
Article
Evaluation of Racial Disparities in Quality of Care for Patients With Gastrointestinal Tract Cancer Treated With Surgery.
Published in:
JAMA Network Open, 2022, v. 5, n. 4, p. e225664, doi. 10.1001/jamanetworkopen.2022.5664
By:
- Bakkila, Baylee F.;
- Kerekes, Daniel;
- Nunez-Smith, Marcella;
- Billingsley, Kevin G.;
- Ahuja, Nita;
- Wang, Karen;
- Oladele, Carol;
- Johnson, Caroline H.;
- Khan, Sajid A.
Publication type:
Article
Metabolomics guided pathway analysis reveals link between cancer metastasis, cholesterol sulfate, and phospholipids.
Published in:
Cancer & Metabolism, 2017, v. 5, p. 1, doi. 10.1186/s40170-017-0171-2
By:
- Johnson, Caroline H.;
- Santidrian, Antonio F.;
- LeBoeuf, Sarah E.;
- Kurczy, Michael E.;
- Rattray, Nicholas J. W.;
- Rattray, Zahra;
- Warth, Benedikt;
- Ritland, Melissa;
- Hoang, Linh T.;
- Loriot, Celine;
- Higa, Jason;
- Hansen, James E.;
- Felding, Brunhilde H.;
- Siuzdak, Gary
Publication type:
Article
Metabolic dysregulation in vitamin E and carnitine shuttle energy mechanisms associate with human frailty.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12716-2
By:
- Rattray, Nicholas J. W.;
- Trivedi, Drupad K.;
- Xu, Yun;
- Chandola, Tarani;
- Johnson, Caroline H.;
- Marshall, Alan D.;
- Mekli, Krisztina;
- Rattray, Zahra;
- Tampubolon, Gindo;
- Vanhoutte, Bram;
- White, Iain R.;
- Wu, Frederick C. W.;
- Pendleton, Neil;
- Nazroo, James;
- Goodacre, Royston
Publication type:
Article
Molecular Mechanisms of Alcohol-Induced Colorectal Carcinogenesis.
Published in:
Cancers, 2021, v. 13, n. 17, p. 4404, doi. 10.3390/cancers13174404
By:
- Johnson, Caroline H.;
- Golla, Jaya Prakash;
- Dioletis, Evangelos;
- Singh, Surendra;
- Ishii, Momoko;
- Charkoftaki, Georgia;
- Thompson, David C.;
- Vasiliou, Vasilis
Publication type:
Article
Global metabolomics reveals metabolic dysregulation in ischemic retinopathy.
Published in:
Metabolomics, 2016, v. 12, n. 1, p. N.PAG, doi. 10.1007/s11306-015-0877-5
By:
- Paris, Liliana P.;
- Johnson, Caroline H.;
- Aguilar, Edith;
- Usui, Yoshihiko;
- Cho, Kevin;
- Hoang, Lihn T.;
- Feitelberg, Daniel;
- Benton, H. Paul;
- Westenskow, Peter D.;
- Kurihara, Toshihide;
- Trombley, Jennifer;
- Tsubota, Kinya;
- Ueda, Shunichiro;
- Wakabayashi, Yoshihiro;
- Patti, Gary J.;
- Ivanisevic, Julijana;
- Siuzdak, Gary;
- Friedlander, Martin
Publication type:
Article
Urinary phenol concentrations and fecundability and early pregnancy loss.
Published in:
2023
By:
- Vollmar, Ana K Rosen;
- Weinberg, Clarice R;
- Baird, Donna D;
- Wilcox, Allen J;
- Calafat, Antonia M;
- Deziel, Nicole C;
- Johnson, Caroline H;
- Jukic, Anne Marie Z;
- Rosen Vollmar, Ana K
Publication type:
journal article
Sex Differences in Colon Cancer Metabolism Reveal A Novel Subphenotype.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-61851-0
By:
- Cai, Yuping;
- Rattray, Nicholas J. W.;
- Zhang, Qian;
- Mironova, Varvara;
- Santos-Neto, Alvaro;
- Hsu, Kuo-Shun;
- Rattray, Zahra;
- Cross, Justin R.;
- Zhang, Yawei;
- Paty, Philip B.;
- Khan, Sajid A.;
- Johnson, Caroline H.
Publication type:
Article
Bile acid distributions, sex-specificity, and prognosis in colorectal cancer.
Published in:
Biology of Sex Differences, 2022, v. 13, n. 1, p. 1, doi. 10.1186/s13293-022-00473-9
By:
- Cai, Yuping;
- Shen, Xinyi;
- Lu, Lingeng;
- Yan, Hong;
- Huang, Huang;
- Gaule, Patricia;
- Muca, Engjel;
- Theriot, Casey M.;
- Rattray, Zahra;
- Rattray, Nicholas J. W.;
- Lu, Jun;
- Ahuja, Nita;
- Zhang, Yawei;
- Paty, Philip B.;
- Khan, Sajid A.;
- Johnson, Caroline H.
Publication type:
Article
PPARα regulates tumor cell proliferation and senescence via a novel target gene carnitine palmitoyltransferase 1C.
Published in:
Carcinogenesis, 2017, v. 38, n. 4, p. 474, doi. 10.1093/carcin/bgx023
By:
- Yixin Chen;
- Yongtao Wang;
- Yaoyao Huang;
- Hang Zeng;
- Bingfang Hu;
- Lihuan Guan;
- Huizhen Zhang;
- Ai-Ming Yu;
- Johnson, Caroline H.;
- Gonzalez, Frank J.;
- Min Huang;
- Huichang Bi
Publication type:
Article
N-methylnicotinamide and nicotinamide N-methyltransferase are associated with microRNA-1291-altered pancreatic carcinoma cell metabolome and suppressed tumorigenesis.
Published in:
Carcinogenesis, 2014, v. 35, n. 10, p. 2264, doi. 10.1093/carcin/bgu174
By:
- Bi, Hui-Chang;
- Pan, Yu-Zhuo;
- Qiu, Jing-Xin;
- Krausz, Kristopher W.;
- Li, Fei;
- Johnson, Caroline H.;
- Jiang, Chang-Tao;
- Gonzalez, Frank J.;
- Yu, Ai-Ming
Publication type:
Article
Comprehensive bioimaging with fluorinated nanoparticles using breathable liquids.
Published in:
Nature Communications, 2015, v. 6, n. 1, p. 5998, doi. 10.1038/ncomms6998
By:
- Kurczy, Michael E.;
- Zhu, Zheng-Jiang;
- Ivanisevic, Julijana;
- Schuyler, Adam M.;
- Lalwani, Kush;
- Santidrian, Antonio F.;
- David, John M.;
- Giddabasappa, Anand;
- Roberts, Amanda J.;
- Olivos, Hernando J.;
- O'Brien, Peter J.;
- Franco, Lauren;
- Fields, Matthew W.;
- Paris, Liliana P.;
- Friedlander, Martin;
- Johnson, Caroline H.;
- Epstein, Adrian A.;
- Gendelman, Howard E.;
- Wood, Malcolm R.;
- Felding, Brunhilde H.
Publication type:
Article
Urinary Paraben Concentrations and Associations with the Periconceptional Urinary Metabolome: Untargeted and Targeted Metabolomics Analyses of Participants from the Early Pregnancy Study.
Published in:
Environmental Health Perspectives, 2023, v. 131, n. 9, p. 097006-1, doi. 10.1289/EHP12125
By:
- Rosen Vollmar, Ana K.;
- Rattray, Nicholas J. W.;
- Yuping Cai;
- Jain, Abhishek;
- Hong Yan;
- Deziel, Nicole C.;
- Calafat, Antonia M.;
- Wilcox, Allen J.;
- Jukic, Anne Marie Z.;
- Johnson, Caroline H.
Publication type:
Article
High-performance liquid chromatography/mass spectrometric and proton nuclear magnetic resonance spectroscopic studies of the transacylation and hydrolysis of the acyl glucuronides of a series of phenylacetic acids in buffer and human plasma.
Published in:
Rapid Communications in Mass Spectrometry: RCM, 2010, v. 24, n. 20, p. 3043, doi. 10.1002/rcm.4740
By:
- Karlsson, Elin S.;
- Johnson, Caroline H.;
- Sarda, Sunil;
- Iddon, Lisa;
- Iqbal, Mazhar;
- Meng, Xiaoli;
- Harding, John R.;
- Stachulski, Andrew V.;
- Nicholson, Jeremy K.;
- Wilson, Ian D.;
- Lindon, John C.
Publication type:
Article
Immune landscape and prognostic immune-related genes in KRAS-mutant colorectal cancer patients.
Published in:
2021
By:
- Liu, Jungang;
- Huang, Xiaoliang;
- Liu, Haizhou;
- Wei, Chunyin;
- Ru, Haiming;
- Qin, Haiquan;
- Lai, Hao;
- Meng, Yongsheng;
- Wu, Guo;
- Xie, Weishun;
- Mo, Xianwei;
- Johnson, Caroline H.;
- Zhang, Yawei;
- Tang, Weizhong
Publication type:
journal article
Charting the metabolic biogeography of the colorectum in cancer: challenging the right sided versus left sided classification.
Published in:
Molecular Cancer, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12943-024-02133-5
By:
- Jain, Abhishek;
- Morris, Montana T.;
- Berardi, Domenica;
- Arora, Trisha;
- Domingo-Almenara, Xavier;
- Paty, Philip B.;
- Rattray, Nicholas J. W.;
- Kerekes, Daniel;
- Lu, Lingeng;
- Khan, Sajid A.;
- Johnson, Caroline H.
Publication type:
Article
YIV-906 potentiated anti-PD1 action against hepatocellular carcinoma by enhancing adaptive and innate immunity in the tumor microenvironment.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-91623-3
By:
- Yang, Xiaochen;
- Lam, Wing;
- Jiang, Zaoli;
- Guan, Fulan;
- Han, Xue;
- Hu, Rong;
- Cai, Wei;
- Cheng, William;
- Liu, Shwu-Huey;
- Cheng, Peikwen;
- Cai, Yuping;
- Rattray, Nicholas J. W.;
- Johnson, Caroline H.;
- Chen, Lieping;
- Cheng, Yung-Chi
Publication type:
Article
Defining Early-Onset Colon and Rectal Cancers.
Published in:
Frontiers in Oncology, 2018, p. N.PAG, doi. 10.3389/fonc.2018.00504
By:
- Jacobs, Daniel;
- Zhu, Rebecca;
- Luo, Jiajun;
- Grisotti, Gabriella;
- Heller, Danielle R.;
- Kurbatov, Vadim;
- Johnson, Caroline H.;
- Zhang, Yawei;
- Khan, Sajid A.
Publication type:
Article
Radiation Metabolomics. 5. Identification of Urinary Biomarkers of Ionizing Radiation Exposure in Nonhuman Primates by Mass Spectrometry-Based Metabolomics.
Published in:
Radiation Research, 2012, v. 178, n. 4, p. 328, doi. 10.1667/RR2950.1
By:
- Johnson, Caroline H.;
- Patterson, Andrew D.;
- Krausz, Kristopher W.;
- Kalinich, John F.;
- Tyburski, John B.;
- Kang, Dong Wook;
- Luecke, Hans;
- Gonzalez, Frank J.;
- Blakely, William F.;
- Idle, Jeffrey R.
Publication type:
Article
Ferroptosis in colorectal cancer: a future target?
Published in:
British Journal of Cancer, 2023, v. 128, n. 8, p. 1439, doi. 10.1038/s41416-023-02149-6
By:
- Yan, Hong;
- Talty, Ronan;
- Aladelokun, Oladimeji;
- Bosenberg, Marcus;
- Johnson, Caroline H.
Publication type:
Article
Challenges and opportunities of metabolomics.
Published in:
Journal of Cellular Physiology, 2012, v. 227, n. 8, p. 2975, doi. 10.1002/jcp.24002
By:
- Johnson, Caroline H.;
- Gonzalez, Frank J.
Publication type:
Article
Joint effect of pre-operative anemia and perioperative blood transfusion on outcomes of colon-cancer patients undergoing colectomy.
Published in:
Gastroenterology Report, 2020, v. 8, n. 2, p. 151, doi. 10.1093/gastro/goz033
By:
- Liu, Zheng;
- Luo, Jia-Jun;
- Pei, Kevin Y;
- Khan, Sajid A;
- Wang, Xiao-Xu;
- Zhao, Zhi-Xun;
- Yang, Ming;
- Johnson, Caroline H;
- Wang, Xi-Shan;
- Zhang, Yawei
Publication type:
Article
Arteriovenous Blood Metabolomics: A Readout of Intra-Tissue Metabostasis.
Published in:
Scientific Reports, 2015, p. 12757, doi. 10.1038/srep12757
By:
- Ivanisevic, Julijana;
- Elias, Darlene;
- Deguchi, Hiroshi;
- Averell, Patricia M.;
- Kurczy, Michael;
- Johnson, Caroline H.;
- Tautenhahn, Ralf;
- Zhu, Zhengjiang;
- Watrous, Jeramie;
- Jain, Mohit;
- Griffin, John;
- Patti, Gary J.;
- Siuzdak, Gary
Publication type:
Article
Development of an Accessible Gene Expression Bioinformatics Pipeline to Study Driver Mutations of Colorectal Cancer.
Published in:
Alternatives to Laboratory Animals, 2022, v. 50, n. 4, p. 282, doi. 10.1177/02611929221107546
By:
- van den Driest, Lisa;
- Johnson, Caroline H.;
- Rattray, Nicholas J.W.;
- Rattray, Zahra
Publication type:
Article
Evaluation of the role of KPNA2 mutations in breast cancer prognosis using bioinformatics datasets.
Published in:
2022
By:
- Alnoumas, Layla;
- van den Driest, Lisa;
- Apczynski, Zoe;
- Lannigan, Alison;
- Johnson, Caroline H;
- Rattray, Nicholas J W;
- Rattray, Zahra
Publication type:
journal article
Gene Alterations of N6-Methyladenosine (m<sup>6</sup>A) Regulators in Colorectal Cancer: A TCGA Database Study.
Published in:
BioMed Research International, 2020, p. 1, doi. 10.1155/2020/8826456
By:
- Zhang, Qian;
- Cai, Yuping;
- Kurbatov, Vadim;
- Khan, Sajid A.;
- Lu, Lingeng;
- Zhang, Yawei;
- Johnson, Caroline H.
Publication type:
Article
Liquid chromatography quadrupole time-of-flight mass spectrometry characterization of metabolites guided by the METLIN database.
Published in:
Nature Protocols, 2013, v. 8, n. 3, p. 451, doi. 10.1038/nprot.2013.004
By:
- Zhu, Zheng-Jiang;
- Schultz, Andrew W;
- Wang, Junhua;
- Johnson, Caroline H;
- Yannone, Steven M;
- Patti, Gary J;
- Siuzdak, Gary
Publication type:
Article
Identification of Dose-Dependent DNA Damage and Repair Responses From Subchronic Exposure to 1,4-Dioxane in Mice Using a Systems Analysis Approach.
Published in:
Toxicological Sciences, 2021, v. 183, n. 2, p. 338, doi. 10.1093/toxsci/kfab030
By:
- Charkoftaki, Georgia;
- Golla, Jaya Prakash;
- Santos-Neto, Alvaro;
- Orlicky, David J;
- Garcia-Milian, Rolando;
- Chen, Ying;
- Rattray, Nicholas J W;
- Cai, Yuping;
- Wang, Yewei;
- Shearn, Colin T;
- Mironova, Varvara;
- Wang, Yensheng;
- Johnson, Caroline H;
- Thompson, David C;
- Vasiliou, Vasilis
Publication type:
Article
Determining conserved metabolic biomarkers from a million database queries.
Published in:
Bioinformatics, 2015, v. 31, n. 23, p. 3721, doi. 10.1093/bioinformatics/btv475
By:
- Kurczy, Michael E.;
- Ivanisevic, Julijana;
- Johnson, Caroline H.;
- Uritboonthai, Winnie;
- Linh Hoang;
- Mingliang Fang;
- Hicks, Matthew;
- Aldebot, Anthony;
- Rinehart, Duane;
- Mellander, Lisa J.;
- Tautenhahn, Ralf;
- Patti, Gary J.;
- Spilker, Mary E.;
- Benton, H. Paul;
- Siuzdak, Gary
Publication type:
Article
Prenatal Choline Supplement in a Maternal Obesity Model Modulates Offspring Hepatic Lipidomes.
Published in:
Nutrients, 2023, v. 15, n. 4, p. 965, doi. 10.3390/nu15040965
By:
- Korsmo, Hunter W.;
- Kadam, Isma'il;
- Reaz, Aziza;
- Bretter, Rachel;
- Saxena, Anjana;
- Johnson, Caroline H.;
- Caviglia, Jorge Matias;
- Jiang, Xinyin
Publication type:
Article

Found: 41