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Molecularly Targeted Therapies for Triple Negative Breast Cancer: History, Advances, and Future Directions.
Published in:
Clinical Breast Cancer, 2023, v. 23, n. 8, p. 784, doi. 10.1016/j.clbc.2023.05.012
By:
- Mai, Nicholas;
- Abuhadra, Nour;
- Jhaveri, Komal
Publication type:
Article
SUMMIT Reveals Promise of Neratinib in HE2 Mutant Metastatic Breast Cancer.
Published in:
Clinical Breast Cancer, 2022, p. 8
By:
- Jhaveri, Komal
Publication type:
Article
Biomarkers That Predict Sensitivity to Heat Shock Protein 90 Inhibitors.
Published in:
2016
By:
- Jhaveri, Komal;
- Chandarlapaty, Sarat;
- Iyengar, Neil;
- Morris, Patrick G.;
- Corben, Adriana D.;
- Patil, Sujata;
- Akram, Muzaffar;
- Towers, Russell;
- Sakr, Rita A.;
- King, Tari A.;
- Norton, Larry;
- Rosen, Neal;
- Hudis, Clifford;
- Modi, Shanu
Publication type:
journal article
Hyperactivated mTOR and JAK2/STAT3 Pathways: Molecular Drivers and Potential Therapeutic Targets of Inflammatory and Invasive Ductal Breast Cancers After Neoadjuvant Chemotherapy.
Published in:
2016
By:
- Jhaveri, Komal;
- Teplinsky, Eleonora;
- Silvera, Deborah;
- Valeta-Magara, Amanda;
- Arju, Rezina;
- Giashuddin, Shah;
- Sarfraz, Yasmeen;
- Alexander, Melissa;
- Darvishian, Farbod;
- Levine, Paul H.;
- Hashmi, Salman;
- Zolfaghari, Ladan;
- Hoffman, Heather J.;
- Singh, Baljit;
- Goldberg, Judith D.;
- Hochman, Tsivia;
- Formenti, Silvia;
- Esteva, Francisco J.;
- Moran, Meena S.;
- Schneider, Robert J.
Publication type:
journal article
A Phase II Open-Label Study of Ganetespib, a Novel Heat Shock Protein 90 Inhibitor for Patients With Metastatic Breast Cancer.
Published in:
Clinical Breast Cancer, 2014, v. 14, n. 3, p. 154, doi. 10.1016/j.clbc.2013.12.012
By:
- Jhaveri, Komal;
- Chandarlapaty, Sarat;
- Lake, Diana;
- Gilewski, Teresa;
- Robson, Mark;
- Goldfarb, Shari;
- Drullinsky, Pamela;
- Sugarman, Steven;
- Leiblich, Carolyn Wasserheit;
- Fasano, Julie;
- Moynahan, Mary Ellen;
- D'Andrea, Gabriella;
- Lim, Kristina;
- Reddington, Laura;
- Haque, Sofia;
- Patil, Sujata;
- Bauman, Lynne;
- Vukovic, Vojo;
- El-Hariry, Iman;
- Hudis, Clifford
Publication type:
Article
Targeting Tumor Angiogenesis in Combination with Endocrine Therapy in Patients with Hormone-Receptor Positive Metastatic Breast Cancer.
Published in:
European Journal of Clinical & Medical Oncology, 2011, v. 3, n. 4, p. 24
By:
- Jhaveri, Komal;
- Traina, Tiffany;
- Rugo, Hope;
- Geneus, Stephanie;
- Patil, Sujata;
- Hudis, Clifford;
- Dickler, Maura N.
Publication type:
Article
The oral selective estrogen receptor degrader GDC-0810 (ARN-810) in postmenopausal women with hormone receptor-positive HER2-negative (HR + /HER2 −) advanced/metastatic breast cancer.
Published in:
Breast Cancer Research & Treatment, 2023, v. 197, n. 2, p. 319, doi. 10.1007/s10549-022-06797-9
By:
- Bardia, Aditya;
- Mayer, Ingrid;
- Winer, Eric;
- Linden, Hannah M.;
- Ma, Cynthia X.;
- Parker, Barbara A.;
- Bellet, Meritxell;
- Arteaga, Carlos L.;
- Cheeti, Sravanthi;
- Gates, Mary;
- Chang, Ching-Wei;
- Fredrickson, Jill;
- Spoerke, Jill M.;
- Moore, Heather M.;
- Giltnane, Jennifer;
- Friedman, Lori S.;
- Chow Maneval, Edna;
- Chan, Iris;
- Jhaveri, Komal
Publication type:
Article
A phase I trial of sorafenib with whole brain radiotherapy (WBRT) in breast cancer patients with brain metastases and a correlative study of FLT-PET brain imaging.
Published in:
Breast Cancer Research & Treatment, 2021, v. 188, n. 2, p. 415, doi. 10.1007/s10549-021-06209-4
By:
- Morikawa, Aki;
- Grkovski, Milan;
- Patil, Sujata;
- Jhaveri, Komal L.;
- Tang, Kendrick;
- Humm, John L.;
- Holodny, Andrei;
- Beal, Kathryn;
- Schöder, Heiko;
- Seidman, Andrew D.
Publication type:
Article
Dermatologic adverse events related to the PI3Kα inhibitor alpelisib (BYL719) in patients with breast cancer.
Published in:
Breast Cancer Research & Treatment, 2020, v. 183, n. 1, p. 227, doi. 10.1007/s10549-020-05726-y
By:
- Wang, Diana G.;
- Barrios, Dulce M.;
- Blinder, Victoria S.;
- Bromberg, Jacqueline F.;
- Drullinsky, Pamela R.;
- Funt, Samuel A.;
- Jhaveri, Komal L.;
- Lake, Diana E.;
- Lyons, Tomas;
- Modi, Shanu;
- Razavi, Pedram;
- Sidel, Michelle;
- Traina, Tiffany A.;
- Vahdat, Linda T.;
- Lacouture, Mario E.
Publication type:
Article
Matching-adjusted indirect comparison of PFS and OS comparing ribociclib plus letrozole versus palbociclib plus letrozole as first-line treatment of HR+/HER2− advanced breast cancer.
Published in:
Therapeutic Advances in Medical Oncology, 2023, p. 1, doi. 10.1177/17588359231216095
By:
- Jhaveri, Komal;
- O'Shaughnessy, Joyce;
- Fasching, Peter A.;
- Tolaney, Sara M.;
- Yardley, Denise A.;
- Sharma, Vikash Kumar;
- Biswas, Chandroday;
- Thuerigen, Astrid;
- Pathak, Purnima;
- Rugo, Hope S.
Publication type:
Article
Quality of life with ribociclib versus abemaciclib as first-line treatment of HR+/HER2− advanced breast cancer: a matching-adjusted indirect comparison.
Published in:
Therapeutic Advances in Medical Oncology, 2023, p. 1, doi. 10.1177/17588359231152843
By:
- Rugo, Hope S.;
- Harmer, Victoria;
- O'Shaughnessy, Joyce;
- Jhaveri, Komal;
- Tolaney, Sara M.;
- Cardoso, Fatima;
- Bardia, Aditya;
- Maheshwari, Vikalp Kumar;
- Tripathi, Sandeep;
- Haftchenary, Sina;
- Pathak, Purnima;
- Fasching, Peter A.
Publication type:
Article
How Effective is Neoadjuvant Endocrine Therapy (NET) in Downstaging the Axilla and Achieving Breast-Conserving Surgery?
Published in:
Annals of Surgical Oncology: An Oncology Journal for Surgeons, 2020, v. 27, n. 12, p. 4702, doi. 10.1245/s10434-020-08888-7
By:
- Montagna, Giacomo;
- Sevilimedu, Varadan;
- Fornier, Monica;
- Jhaveri, Komal;
- Morrow, Monica;
- Pilewskie, Melissa L.
Publication type:
Article
A phase 1b dose expansion study of the pan-class I PI3K inhibitor buparlisib (BKM120) plus carboplatin and paclitaxel in PTEN deficient tumors and with dose intensified carboplatin and paclitaxel.
Published in:
Investigational New Drugs, 2017, v. 35, n. 6, p. 742, doi. 10.1007/s10637-017-0445-0
By:
- Smyth, Lillian;
- Monson, Kelsey;
- Jhaveri, Komal;
- Drilon, Alexander;
- Li, Bob;
- Abida, Wassim;
- Iyer, Gopa;
- Gerecitano, John;
- Gounder, Mrinal;
- Harding, James;
- Voss, Martin;
- Makker, Vicky;
- Ho, Alan;
- Razavi, Pedram;
- Iasonos, Alexia;
- Bialer, Philip;
- Lacouture, Mario;
- Teitcher, Jerrold;
- Erinjeri, Joseph;
- Katabi, Nora
Publication type:
Article
Voxelwise analysis of simultaneously acquired and spatially correlated 18F-fluorodeoxyglucose (FDG)-PET and intravoxel incoherent motion metrics in breast cancer.
Published in:
Magnetic Resonance in Medicine, 2017, v. 78, n. 3, p. 1147, doi. 10.1002/mrm.26505
By:
- Ostenson, Jason;
- Pujara, Akshat C.;
- Mikheev, Artem;
- Moy, Linda;
- Kim, Sungheon G.;
- Melsaether, Amy N.;
- Jhaveri, Komal;
- Adams, Sylvia;
- Faul, David;
- Glielmi, Christopher;
- Geppert, Christian;
- Feiweier, Thorsten;
- Jackson, Kimberly;
- Cho, Gene Y.;
- Boada, Fernando E.;
- Sigmund, Eric E.
Publication type:
Article
Selective AKT kinase inhibitor capivasertib in combination with fulvestrant in PTEN-mutant ER-positive metastatic breast cancer.
Published in:
NPJ Breast Cancer, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41523-021-00251-7
By:
- Smyth, Lillian M.;
- Batist, Gerald;
- Meric-Bernstam, Funda;
- Kabos, Peter;
- Spanggaard, Iben;
- Lluch, Ana;
- Jhaveri, Komal;
- Varga, Andrea;
- Wong, Andrea;
- Schram, Alison M.;
- Ambrose, Helen;
- Carr, T. Hedley;
- de Bruin, Elza C.;
- Salinas-Souza, Carolina;
- Foxley, Andrew;
- Hauser, Joana;
- Lindemann, Justin P. O.;
- Maudsley, Rhiannon;
- McEwen, Robert;
- Moschetta, Michele
Publication type:
Article
A phase I trial of ganetespib in combination with paclitaxel and trastuzumab in patients with human epidermal growth factor receptor-2 (HER2)-positive metastatic breast cancer.
Published in:
2017
By:
- Jhaveri, Komal;
- Rui Wang;
- Teplinsky, Eleonora;
- Chandarlapaty, Sarat;
- Solit, David;
- Cadoo, Karen;
- Speyer, James;
- D'Andrea, Gabriella;
- Adams, Sylvia;
- Patil, Sujata;
- Haque, Sofia;
- O'Neill, Tara;
- Friedman, Kent;
- Esteva, Francisco J.;
- Hudis, Clifford;
- Modi, Shanu;
- Wang, Rui
Publication type:
journal article
Balancing the Risks and Benefits of Extended Adjuvant Endocrine Therapy.
Published in:
Clinical Advances in Hematology & Oncology, 2019, v. 17, n. 2, p. 105
By:
- Jhaveri, Komal L.
Publication type:
Article
Fatal hepatitis B reactivation due to everolimus in metastatic breast cancer: case report and review of literature.
Published in:
Breast Cancer Research & Treatment, 2013, v. 141, n. 2, p. 167, doi. 10.1007/s10549-013-2681-0
By:
- Teplinsky, Eleonora;
- Cheung, Derrick;
- Weisberg, Ilan;
- Jacobs, Ramon;
- Wolff, Martin;
- Park, James;
- Friedman, Kent;
- Muggia, Franco;
- Jhaveri, Komal
Publication type:
Article
Erythema nodosum secondary to aromatase inhibitor use in breast cancer patients: case reports and review of the literature.
Published in:
Breast Cancer Research & Treatment, 2007, v. 106, n. 3, p. 315, doi. 10.1007/s10549-007-9518-7
By:
- Komal Jhaveri;
- Peter Halperin;
- Sandra Shin;
- Linda Vahdat
Publication type:
Article
Characterization, management, and risk factors of hyperglycemia during PI3K or AKT inhibitor treatment.
Published in:
Cancer Medicine, 2022, v. 11, n. 8, p. 1796, doi. 10.1002/cam4.4579
By:
- Liu, Dazhi;
- Weintraub, Michael A.;
- Garcia, Christine;
- Goncalves, Marcus D.;
- Sisk, Ann Elizabeth;
- Casas, Alissa;
- Harding, James J.;
- Harnicar, Stephen;
- Drilon, Alexander;
- Jhaveri, Komal;
- Flory, James H.
Publication type:
Article
Clinical and Morphologic Characteristics of Fibroblast Growth Factor Receptor Inhibitor-Associated Retinopathy.
Published in:
2021
By:
- Francis, Jasmine H.;
- Harding, James J.;
- Schram, Alison M.;
- Canestraro, Julia;
- Haggag-Lindgren, Dianna;
- Heinemann, Murk;
- Kriplani, Anuja;
- Jhaveri, Komal;
- Voss, Martin H.;
- Bajorin, Dean;
- Abou-Alfa, Ghassan K.;
- Iyer, Gopa;
- Drilon, Alexander;
- Rosenberg, Jonathan;
- Abramson, David H.
Publication type:
journal article
Abemaciclib in Combination With Endocrine Therapy for Patients With Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer: A Phase 1b Study.
Published in:
Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2021.810023
By:
- Tolaney, Sara M.;
- Beeram, Muralidhar;
- Beck, J. Thaddeus;
- Conlin, Alison;
- Dees, E. Claire;
- Puhalla, Shannon L.;
- Rexer, Brent N.;
- Burris 3rd, Howard A.;
- Jhaveri, Komal;
- Helsten, Teresa;
- Becerra, Carlos;
- Kalinsky, Kevin;
- Moore, Kathleen N.;
- Manuel, Allison M.;
- Lithio, Andrew;
- Price, Gregory L.;
- Chapman, Sonya C.;
- Litchfield, Lacey M.;
- Goetz, Matthew P.
Publication type:
Article
Phase 2 trial of everolimus and carboplatin combination in patients with triple negative metastatic breast cancer.
Published in:
2014
By:
- Singh, Jasmeet;
- Novik, Yelena;
- Stein, Stacey;
- Volm, Matthew;
- Meyers, Marlene;
- Smith, Julia;
- Omene, Coral;
- Speyer, James;
- Schneider, Robert;
- Jhaveri, Komal;
- Formenti, Silvia;
- Kyriakou, Victoria;
- Joseph, Benson;
- Goldberg, Judith D;
- Li, Xiaochun;
- Adams, Sylvia;
- Tiersten, Amy
Publication type:
journal article
Efficacy and Safety of Gemcitabine With Trastuzumab and Pertuzumab After Prior Pertuzumab-Based Therapy Among Patients With Human Epidermal Growth Factor Receptor 2–Positive Metastatic Breast Cancer: A Phase 2 Clinical Trial.
Published in:
JAMA Network Open, 2019, v. 2, n. 11, p. e1916211, doi. 10.1001/jamanetworkopen.2019.16211
By:
- Iyengar, Neil M.;
- Smyth, Lillian M.;
- Lake, Diana;
- Gucalp, Ayca;
- Singh, Jasmeet C.;
- Traina, Tiffany A.;
- DeFusco, Patricia;
- Fornier, Monica N.;
- Goldfarb, Shari;
- Jhaveri, Komal;
- Modi, Shanu;
- Troso-Sandoval, Tiffany;
- Patil, Sujata;
- Ulaner, Gary A.;
- Jochelson, Maxine;
- Norton, Larry;
- Hudis, Clifford A.;
- Dang, Chau T.
Publication type:
Article
F-FDG PET/CT in metastatic invasive lobular breast cancer.
Published in:
Journal of Nuclear Medicine, 2020, v. 61, n. 12, p. 1, doi. 10.2967/jnumed.120.247882
By:
- Ulaner, Gary A.;
- Jhaveri, Komal;
- Chandarlapaty, Sarat;
- Hatzoglou, Vaios;
- Riedl, Christopher C.;
- Lewis, Jason S.;
- Mauguen, Audrey
Publication type:
Article
Head-to-head evaluation of 18F-FES and 18F-FDG PET/CT in metastatic invasive lobular breast cancer.
Published in:
Journal of Nuclear Medicine, 2020, v. 61, n. 11, p. 1, doi. 10.2967/jnumed.120.247882
By:
- Ulaner, Gary A.;
- Jhaveri, Komal;
- Chandarlapaty, Sarat;
- Hatzoglou, Vaios;
- Riedl, Christopher C.;
- Lewis, Jason S.;
- Mauguen, Audrey
Publication type:
Article
Head-to-head evaluation of 18F-FES and 18F-FDG PET/CT in metastatic invasive lobular breast cancer.
Published in:
Journal of Nuclear Medicine, 2020, v. 61, n. 10, p. 1, doi. 10.2967/jnumed.120.247882
By:
- Ulaner, Gary A.;
- Jhaveri, Komal;
- Chandarlapaty, Sarat;
- Hatzoglou, Vaios;
- Riedl, Christopher C.;
- Lewis, Jason S.;
- Mauguen, Audrey
Publication type:
Article
Head-to-head evaluation of 18F-FES and 18F-FDG PET/CT in metastatic invasive lobular breast cancer.
Published in:
Journal of Nuclear Medicine, 2020, v. 61, n. 9, p. 1, doi. 10.2967/jnumed.120.247882
By:
- Ulaner, Gary A.;
- Jhaveri, Komal;
- Chandarlapaty, Sarat;
- Hatzoglou, Vaios;
- Riedl, Christopher C.;
- Lewis, Jason S.;
- Mauguen, Audrey
Publication type:
Article
First-in-Human Human Epidermal Growth Factor Receptor 2-Targeted Imaging Using 89Zr-Pertuzumab PET/CT: Dosimetry and Clinical Application in Patients with Breast Cancer.
Published in:
Journal of Nuclear Medicine, 2018, v. 59, n. 6, p. 900, doi. 10.2967/jnumed.117.202010
By:
- Ulaner, Gary A.;
- Lyashchenko, Serge K.;
- Riedl, Christopher;
- Ruan, Shutian;
- Zanzonico, Pat B.;
- Lake, Diana;
- Jhaveri, Komal;
- Zeglis, Brian;
- Lewis, Jason S.;
- O'Donoghue, Joseph A.
Publication type:
Article
Imaging Diagnostic and Therapeutic Targets: Human Epidermal Growth Factor Receptor 2.
Published in:
Journal of Nuclear Medicine, 2016, v. 57, p. 81S, doi. 10.2967/jnumed.115.157941
By:
- Gebhart, Geraldine;
- Flamen, Patrick;
- De Vries, Elisabeth G. E.;
- Jhaveri, Komal;
- Wimana, Zena
Publication type:
Article
Molecular Imaging of Biomarkers in Breast Cancer.
Published in:
Journal of Nuclear Medicine, 2016, v. 57, p. 53S, doi. 10.2967/jnumed.115.157909
By:
- Ulaner, Gary A.;
- Riedl, Chris C.;
- Dickler, Maura N.;
- Jhaveri, Komal;
- Pandit-Taskar, Neeta;
- Weber, Wolfgang
Publication type:
Article
Measuring Tumor Metabolism by 18F-FDG PET Predicts Outcome in a Multicenter Study: A Step Off in the Right Direction.
Published in:
Journal of Nuclear Medicine, 2015, v. 56, n. 1, p. 1, doi. 10.2967/jnumed.114.151175
By:
- Jhaveri, Komal;
- Linden, Hannah
Publication type:
Article
Treatment of Metastatic Extramammary Paget Disease with Combination Ipilimumab and Nivolumab: A Case Report.
Published in:
Case Reports in Oncology, 2021, v. 14, n. 1, p. 430, doi. 10.1159/000514345
By:
- Guercio, Brendan John;
- Iyer, Gopa;
- Kidwai, Wajih Zaheer;
- Lacouture, Mario E.;
- Ghafoor, Soleen;
- Rossi, Anthony M.;
- Assis, David N.;
- Chen, Ying-Bei;
- Busam, Klaus J.;
- Janjigian, Yelena Y.;
- Jhaveri, Komal;
- Feldman, Darren R.;
- Capozzi, Anne;
- Figueroa, Vanessa;
- Bajorin, Dean F.;
- Rosenberg, Jonathan E.;
- Hollmann, Travis J.;
- Funt, Samuel A.
Publication type:
Article
Hepatic Arterial Infusion and Systemic Chemotherapy for Breast Cancer Liver Metastases.
Published in:
Breast Journal, 2013, v. 19, n. 1, p. 96, doi. 10.1111/tbj.12050
By:
- Ang, Celina;
- Jhaveri, Komal;
- Patel, Dina;
- Gewirtz, Alexandra;
- Seidman, Andrew;
- Kemeny, Nancy
Publication type:
Article
Risk of metachronous breast cancer after BRCA mutation-associated ovarian cancer.
Published in:
Cancer (0008543X), 2013, v. 119, n. 7, p. 1344, doi. 10.1002/cncr.27842
By:
- Domchek, Susan M.;
- Jhaveri, Komal;
- Patil, Sujata;
- Stopfer, Jill E.;
- Hudis, Clifford;
- Powers, Jacquelyn;
- Stadler, Zsofia;
- Goldstein, Laura;
- Kauff, Noah;
- Khasraw, Mustafa;
- Offit, Kenneth;
- Nathanson, Katherine L.;
- Robson, Mark
Publication type:
Article
Standardized uptake value by positron emission tomography/computed tomography as a prognostic variable in metastatic breast cancer.
Published in:
Cancer (0008543X), 2012, v. 118, n. 22, p. 5454, doi. 10.1002/cncr.27579
By:
- Morris, Patrick G.;
- Ulaner, Gary A.;
- Eaton, Anne;
- Fazio, Maurizio;
- Jhaveri, Komal;
- Patil, Sujata;
- Evangelista, Laura;
- Park, Joseph Y.;
- Serna-Tamayo, Cristian;
- Howard, Jane;
- Larson, Steven;
- Hudis, Clifford A.;
- McArthur, Heather L.;
- Jochelson, Maxine S.
Publication type:
Article
Predictors of response to CDK4/6i retrial after prior CDK4/6i failure in ER+ metastatic breast cancer.
Published in:
NPJ Breast Cancer, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41523-024-00699-3
By:
- Mai, Nicholas;
- dos Anjos, Carlos H.;
- Razavi, Pedram;
- Safonov, Anton;
- Patil, Sujata;
- Chen, Yuan;
- Drago, Joshua Z.;
- Modi, Shanu;
- Bromberg, Jacqueline F.;
- Dang, Chau T.;
- Liu, Dazhi;
- Norton, Larry;
- Robson, Mark;
- Chandarlapaty, Sarat;
- Jhaveri, Komal
Publication type:
Article
Genome-Based Risk Prediction for Early Stage Breast Cancer.
Published in:
Oncologist, 2014, v. 19, n. 10, p. 1019, doi. 10.1634/theoncologist.2014-0124
By:
- Adaniel, Christina;
- Jhaveri, Komal;
- Heguy, Adriana;
- Esteva, Francisco J.
Publication type:
Article
Ganetespib: research and clinical development.
Published in:
OncoTargets & Therapy, 2015, v. 8, p. 1849, doi. 10.2147/OTT.S65804
By:
- Jhaveri, Komal;
- Modi, Shanu
Publication type:
Article
Clinical implications of drug‐induced liver injury in early‐phase oncology clinical trials.
Published in:
Cancer (0008543X), 2020, v. 126, n. 22, p. 4967, doi. 10.1002/cncr.33153
By:
- Mondaca, Sebastian P.;
- Liu, Dazhi;
- Flynn, Jessica R.;
- Badson, Sandy;
- Hamaway, Stefan;
- Gounder, Mrinal M.;
- Khalil, Danny N.;
- Drilon, Alexander E.;
- Li, Bob T.;
- Jhaveri, Komal L.;
- Schram, Alison M.;
- Kargus, Katherine E.;
- Kasler, Mary Kate;
- Blauvelt, Natalie M.;
- Segal, Neil H.;
- Capanu, Marinela;
- Callahan, Margaret K.;
- Hyman, David M.;
- Gambarin‐Gelwan, Maya;
- Harding, James J.
Publication type:
Article

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