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Effector mechanisms of IgA antibodies against CD20 include recruitment of myeloid cells for antibody‐dependent cell‐mediated cytotoxicity and complement‐dependent cytotoxicity.
Published in:
2018
By:
- Lohse, Stefan;
- Loew, Sebastian;
- Kretschmer, Anna;
- Jansen, J. H. Marco;
- Meyer, Saskia;
- ten Broeke, Toine;
- Rösner, Thies;
- Dechant, Michael;
- Derer, Stefanie;
- Klausz, Katja;
- Kellner, Christian;
- Schwanbeck, Ralf;
- French, Ruth R.;
- Tipton, Thomas R. W.;
- Cragg, Mark S.;
- Schewe, Denis M.;
- Peipp, Matthias;
- Leusen, Jeanette H. W.;
- Valerius, Thomas
Publication type:
Letter to the Editor
The relevance of tumor target expression levels on IgA-mediated cytotoxicity in cancer immunotherapy.
Published in:
Cancer Immunology, Immunotherapy, 2024, v. 73, n. 12, p. 1, doi. 10.1007/s00262-024-03824-0
By:
- Chan, Chilam;
- Cabanes, Núria Casalé;
- Jansen, J. H. Marco;
- Guillaume, Joël;
- Nederend, Maaike;
- Passchier, Elsemieke M.;
- Gómez-Mellado, Valentina E.;
- Peipp, Matthias;
- Boes, Marianne;
- van Tetering, Geert;
- Leusen, Jeanette H. W.
Publication type:
Article
Leukocyte-associated immunoglobulin-like receptor-1 blockade in combination with programmed death-ligand 1 targeting therapy mediates increased tumour control in mice.
Published in:
Cancer Immunology, Immunotherapy, 2024, v. 73, n. 1, p. 1, doi. 10.1007/s00262-023-03600-6
By:
- Singh, Akashdip;
- Mommers-Elshof, Eline T. A. M.;
- Vijver, Saskia V.;
- Jansen, J. H. Marco;
- Gonder, Susanne;
- Lebbink, Robert Jan;
- Bihan, Dominique;
- Farndale, Richard W.;
- Boon, Louis;
- Langermann, Solomon;
- Leusen, Jeanette H. W.;
- Flies, Dallas;
- Meyaard, Linde;
- Pascoal Ramos, M. Ines
Publication type:
Article
Characterization of human Fc alpha receptor transgenic mice: comparison of CD89 expression and antibody-dependent tumor killing between mouse strains.
Published in:
Cancer Immunology, Immunotherapy, 2023, v. 72, n. 9, p. 3063, doi. 10.1007/s00262-023-03478-4
By:
- Stip, Marjolein C.;
- Jansen, J. H. Marco;
- Nederend, Maaike;
- Tsioumpekou, Maria;
- Evers, Mitchell;
- Olofsen, Patricia A.;
- Meyer-Wentrup, Friederike;
- Leusen, Jeanette H. W.
Publication type:
Article
Bovine IgG Prevents Experimental Infection With RSV and Facilitates Human T Cell Responses to RSV.
Published in:
Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.01701
By:
- Nederend, Maaike;
- van Stigt, Arthur H.;
- Jansen, J. H. Marco;
- Jacobino, Shamir R.;
- Brugman, Sylvia;
- de Haan, Cornelis A. M.;
- Bont, Louis J.;
- van Neerven, R. J. Joost;
- Leusen, Jeanette H. W.
Publication type:
Article
Potent Fc Receptor Signaling by IgA Leads to Superior Killing of Cancer Cells by Neutrophils Compared to IgG.
Published in:
Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00704
By:
- Brandsma, Arianne M.;
- Bondza, Sina;
- Evers, Mitchell;
- Koutstaal, Rosanne;
- Nederend, Maaike;
- Jansen, J. H. Marco;
- Rösner, Thies;
- Valerius, Thomas;
- Leusen, Jeanette H. W.;
- ten Broeke, Toine
Publication type:
Article
Sialic Acids on Tumor Cells Modulate IgA Therapy by Neutrophils via Inhibitory Receptors Siglec-7 and Siglec-9.
Published in:
Cancers, 2023, v. 15, n. 13, p. 3405, doi. 10.3390/cancers15133405
By:
- Chan, Chilam;
- Lustig, Marta;
- Jansen, J. H. Marco;
- Garcia Villagrasa, Laura;
- Raymakers, Leon;
- Daamen, Lois A.;
- Valerius, Thomas;
- van Tetering, Geert;
- Leusen, Jeanette H. W.
Publication type:
Article
Disruption of the sialic acid/Siglec-9 axis improves antibody-mediated neutrophil cytotoxicity towards tumor cells.
Published in:
Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1178817
By:
- Lustig, Marta;
- Chan, Chilam;
- Jansen, J. H. Marco;
- Bräutigam, Maria;
- Kölling, Max A.;
- Gehlert, Carina Lynn;
- Baumann, Niklas;
- Mester, Simone;
- Foss, Stian;
- Andersen, Jan Terje;
- Bastian, Lorenz;
- Sondermann, Peter;
- Peipp, Matthias;
- Burger, Renate;
- Leusen, Jeanette H. W.;
- Valerius, Thomas
Publication type:
Article
MCL-1 is required throughout B-cell development and its loss sensitizes specific B-cell subsets to inhibition of BCL-2 or BCL-XL.
Published in:
Cell Death & Disease, 2016, v. 7, n. 8, p. e2345, doi. 10.1038/cddis.2016.237
By:
- Vikström, Ingela B;
- Slomp, Anne;
- Carrington, Emma M;
- Moesbergen, Laura M;
- Chang, Catherine;
- Kelly, Gemma L;
- Glaser, Stefan P;
- Jansen, J H Marco;
- Leusen, Jeanette H W;
- Strasser, Andreas;
- Huang, David C S;
- Lew, Andrew M;
- Peperzak, Victor;
- Tarlinton, David M
Publication type:
Article
Effective, Long-Term, Neutrophil Depletion Using a Murinized Anti-Ly-6G 1A8 Antibody.
Published in:
Cells (2073-4409), 2022, v. 11, n. 21, p. 3406, doi. 10.3390/cells11213406
By:
- Olofsen, Patricia A.;
- Stip, Marjolein C.;
- Jansen, J. H. Marco;
- Chan, Chilam;
- Nederend, Maaike;
- Tieland, Ralph G.;
- Tsioumpekou, Maria;
- Leusen, Jeanette H. W.
Publication type:
Article
Enhancement of epidermal growth factor receptor antibody tumor immunotherapy by glutaminyl cyclase inhibition to interfere with CD47/signal regulatory protein alpha interactions.
Published in:
Cancer Science, 2021, v. 112, n. 8, p. 3029, doi. 10.1111/cas.14999
By:
- Baumann, Niklas;
- Rösner, Thies;
- Jansen, J. H. Marco;
- Chan, Chilam;
- Marie Eichholz, Klara;
- Klausz, Katja;
- Winterberg, Dorothee;
- Müller, Kristina;
- Humpe, Andreas;
- Burger, Renate;
- Peipp, Matthias;
- Schewe, Denis M.;
- Kellner, Christian;
- Leusen, Jeanette H. W.;
- Valerius, Thomas
Publication type:
Article

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