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Genetic Deficiency of Plasma Lipoprotein-Associated Phospholipase A2 (PLA2G7 V297F Null Mutation) and Risk of Alzheimer's Disease in Japan.
Published in:
Journal of Alzheimer's Disease, 2010, v. 21, n. 3, p. 775, doi. 10.3233/JAD-2010-100513
By:
- Koshy, Beena;
- Miyashita, Akinori;
- St. Jean, Pamela;
- Stirnadel, Heide;
- Kaise, Toshihiko;
- Rubio, Justin P.;
- Mooser, Vincent;
- Kuwano, Ryozo;
- Irizarry, Michael C.
Publication type:
Article
Performance characteristics of plasma amyloid-beta 40 and 42 assays.
Published in:
2009
By:
- Okereke OI;
- Xia W;
- Irizarry MC;
- Sun X;
- Qiu WQ;
- Fagan AM;
- Mehta PD;
- Hyman BT;
- Selkoe DJ;
- Grodstein F;
- Okereke, Olivia I;
- Xia, Weiming;
- Irizarry, Michael C;
- Sun, Xiaoyan;
- Qiu, Wei Q;
- Fagan, Anne M;
- Mehta, Pankaj D;
- Hyman, Bradley T;
- Selkoe, Dennis J;
- Grodstein, Francine
Publication type:
journal article
Performance Characteristics of Plasma Amyloid-β 40 and 42 Assays.
Published in:
Journal of Alzheimer's Disease, 2009, v. 16, n. 2, p. 277, doi. 10.3233/JAD-2009-0948
By:
- Okereke, Olivia I.;
- Xia, Weiming;
- Irizarry, Michael C.;
- Sun, Xiaoyan;
- Qiu, Wei Q.;
- Fagan, Anne M.;
- Mehta, Pankaj D.;
- Hyman, Bradley T.;
- Selkoe, Dennis J.;
- Grodstein, Francine
Publication type:
Article
Predictors of placebo group decline in the Alzheimer's disease Assessment Scale-cognitive subscale (ADAS-Cog) in 24 week clinical trials of Alzheimer's disease.
Published in:
2008
By:
- Irizarry MC;
- Webb DJ;
- Bains C;
- Barrett SJ;
- Lai RY;
- Laroche JP;
- Hosford D;
- Maher-Edwards G;
- Weil JG;
- Irizarry, Michael C;
- Webb, David J;
- Bains, Chanchal;
- Barrett, Steven J;
- Lai, Robert Y;
- Laroche, Janette P;
- Hosford, David;
- Maher-Edwards, Gareth;
- Weil, John G
Publication type:
journal article
Alzheimer’s Targeted Treatments: Focus on Amyloid and Inflammation.
Published in:
Journal of Neuroscience, 2023, v. 43, n. 47, p. 7894, doi. 10.1523/JNEUROSCI.1576-23.2023
By:
- Takeshi Iwatsubo;
- Irizarry, Michael C.;
- Lewcock, Joseph W.;
- Carrillo, Maria C.
Publication type:
Article
Plasma pTau217 predicts continuous brain amyloid levels in preclinical and early Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 8, p. 5617, doi. 10.1002/alz.14073
By:
- Devanarayan, Viswanath;
- Doherty, Thomas;
- Charil, Arnaud;
- Sachdev, Pallavi;
- Ye, Yuanqing;
- Murali, Leema Krishna;
- Llano, Daniel A.;
- Zhou, Jin;
- Reyderman, Larisa;
- Hampel, Harald;
- Kramer, Lynn D.;
- Dhadda, Shobha;
- Irizarry, Michael C.
Publication type:
Article
Racial and ethnic differences in plasma biomarker eligibility for a preclinical Alzheimer's disease trial.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 6, p. 3827, doi. 10.1002/alz.13803
By:
- Molina‐Henry, Doris Patricia;
- Raman, Rema;
- Liu, Andy;
- Langford, Oliver;
- Johnson, Keith;
- Shum, Leona K.;
- Glover, Crystal M.;
- Dhadda, Shobha;
- Irizarry, Michael;
- Jimenez‐Maggiora, Gustavo;
- Braunstein, Joel B.;
- Yarasheski, Kevin;
- Venkatesh, Venky;
- West, Tim;
- Verghese, Philip B.;
- Rissman, Robert A.;
- Aisen, Paul;
- Grill, Joshua D.;
- Sperling, Reisa A.
Publication type:
Article
Clinical validation of the PrecivityAD2 blood test: A mass spectrometry‐based test with algorithm combining %p‐tau217 and Aβ42/40 ratio to identify presence of brain amyloid.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 5, p. 3179, doi. 10.1002/alz.13764
By:
- Meyer, Matthew R.;
- Kirmess, Kristopher M.;
- Eastwood, Stephanie;
- Wente‐Roth, Traci L.;
- Irvin, Faith;
- Holubasch, Mary S.;
- Venkatesh, Venky;
- Fogelman, Ilana;
- Monane, Mark;
- Hanna, Lucy;
- Rabinovici, Gil D.;
- Siegel, Barry A.;
- Whitmer, Rachel A.;
- Apgar, Charles;
- Bateman, Randall J.;
- Holtzman, David M.;
- Irizarry, Michael;
- Verbel, David;
- Sachdev, Pallavi;
- Ito, Satoshi
Publication type:
Article
Lewy body dementia: Overcoming barriers and identifying solutions.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 3, p. 2298, doi. 10.1002/alz.13674
By:
- Agarwal, Kanishka;
- Backler, Wendi;
- Bayram, Ece;
- Bloom, Leah;
- Boeve, Bradley F.;
- Cha, Jang‐Ho;
- Denslow, Maria;
- Ferman, Tanis J.;
- Galasko, Douglas;
- Galvin, James E.;
- Gomperts, Stephen N.;
- Irizarry, Michael C.;
- Kantarci, Kejal;
- Kaushik, Harsh;
- Kietlinski, Matt;
- Koenig, Aaron;
- Leverenz, James B.;
- McKeith, Ian;
- McLean, Pamela J.;
- Montine, Thomas J.
Publication type:
Article
Predicting clinical progression trajectories of early Alzheimer's disease patients.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 3, p. 1725, doi. 10.1002/alz.13565
By:
- Devanarayan, Viswanath;
- Ye, Yuanqing;
- Charil, Arnaud;
- Andreozzi, Erica;
- Sachdev, Pallavi;
- Llano, Daniel A.;
- Tian, Lu;
- Zhu, Liang;
- Hampel, Harald;
- Kramer, Lynn;
- Dhadda, Shobha;
- Irizarry, Michael
Publication type:
Article
Plasma Aβ42/Aβ40 and phospho‐tau217 concentration ratios increase the accuracy of amyloid PET classification in preclinical Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 2, p. 1214, doi. 10.1002/alz.13542
By:
- Rissman, Robert A.;
- Langford, Oliver;
- Raman, Rema;
- Donohue, Michael C.;
- Abdel‐Latif, Sara;
- Meyer, Matthew R.;
- Wente‐Roth, Traci;
- Kirmess, Kristopher M.;
- Ngolab, Jennifer;
- Winston, Charisse N.;
- Jimenez‐Maggiora, Gustavo;
- Rafii, Michael S.;
- Sachdev, Pallavi;
- West, Tim;
- Yarasheski, Kevin E.;
- Braunstein, Joel B.;
- Irizarry, Michael;
- Johnson, Keith A.;
- Aisen, Paul S.;
- Sperling, Reisa A.
Publication type:
Article
Racial and Ethnic Differences in Plasma Biomarker Eligibility in a Preclinical Alzheimer's Disease Trial.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.083020
By:
- Molina‐Henry, Doris P.;
- Raman, Rema;
- Liu, Andy;
- Langford, Oliver;
- Johnson, Keith A.;
- Shum, Leona K;
- Glover, Crystal M;
- Aisen, Paul S. S;
- Dhadda, Shobha;
- Irizarry, Michael C.;
- Sperling, Reisa A.;
- Grill, Joshua D.
Publication type:
Article
Estimating Braak stage from [18F]MK6240 PET scans.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.083004
By:
- Whittington, Alex;
- Porat, Lily;
- Christian, Bradley T.;
- Devanand, Devanand P.;
- Hostetler, Eric D.;
- Johnson, Keith A.;
- Johnson, Sterling C;
- Klunk, William E;
- Lao, Patrick J.;
- Rowe, Christopher C;
- Devanarayan, Viswanath;
- Reilhac, Anthonin;
- Reyderman, Larisa;
- Irizarry, Michael C.;
- Charil, Arnaud;
- Gunn, Roger N
Publication type:
Article
Discordance in amyloid positivity defined by Visual Reads VR and Centiloids CL.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082823
By:
- Charil, Arnaud;
- Nelson, Todd;
- Devanarayan, Viswanath;
- Reilhac, Anthonin;
- Dhadda, Shobha;
- Reyderman, Larisa;
- Irizarry, Michael C.
Publication type:
Article
Prognostic prediction of the longitudinal cognitive trajectory of amyloid‐positive patients with mild dementia.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.080613
By:
- Devanarayan, Viswanath;
- Charil, Arnaud;
- Sachdev, Pallavi;
- Ye, Yuanqing;
- Koyama, Akihiko;
- Reyderman, Larisa;
- Hampel, Harald;
- Irizarry, Michael C.;
- Dhadda, Shobha;
- Kramer, Lynn D
Publication type:
Article
Development of Clinical Trial Simulation Tools for Alzheimer's Disease through the Critical Path for Alzheimer's Disease (CPAD) Consortium.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.074773
By:
- Sivakumaran, Sudhir;
- Cullen, Nicholas;
- Lau, Corissa;
- Priest, Eileen;
- White, Hazel;
- Irizarry, Michael C.;
- Romero, Klaus;
- Karten, Yashmin
Publication type:
Article
Detection of brain Tau deposition across Braak stages using plasma pTau181, MRI, and cognitive function assessments.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080575
By:
- Devanarayan, Viswanath;
- Charil, Arnaud;
- Sachdev, Pallavi;
- Hu, Helen;
- Nelson, Todd;
- Koyama, Akihiko;
- Reyderman, Larisa;
- Hampel, Harald;
- Irizarry, Michael C.;
- Dhadda, Shobha;
- Kramer, Lynn D
Publication type:
Article
Lecanemab: Amyloid Reduction and Evidence of Downstream Biomarker Modification.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080907
By:
- Irizarry, Michael C.
Publication type:
Article
Harmonization of tau‐PET in Alzheimer's disease: comparison of methods to derive CenTauR units for [18F]RO948, [18F]Flortaucipir, and [18F]MK‐6240.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080421
By:
- Leuzy, Antoine;
- Dore, Vincent;
- Raket, Lars Lau;
- Klein, Gregory;
- Baker, Suzanne L.;
- Carrillo, Maria C.;
- Charil, Arnaud;
- Collins, Emily C.;
- Collins, Jessica A.;
- Haeberlein, Samantha Budd;
- Higuchi, Makoto;
- Hostetler, Eric D.;
- Hutchison, R. Matthew;
- Iaccarino, Leonardo;
- Irizarry, Michael C.;
- Jagust, William J.;
- Johnson, Keith A.;
- Karten, Yashmin;
- Kolb, Hartmuth C.;
- Lopresti, Brian J.
Publication type:
Article
Harmonization of tau‐PET in Alzheimer's disease: comparison of methods to derive CenTauR units for [18F]RO948, [18F]Flortaucipir, and [18F]MK‐6240.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.082006
By:
- Leuzy, Antoine;
- Dore, Vincent;
- Raket, Lars Lau;
- Klein, Gregory;
- Baker, Suzanne L.;
- Carrillo, Maria C.;
- Charil, Arnaud;
- Collins, Emily C.;
- Collins, Jessica A.;
- Haeberlein, Samantha Budd;
- Higuchi, Makoto;
- Hostetler, Eric D.;
- Hutchison, R. Matthew;
- Iaccarino, Leonardo;
- Irizarry, Michael C.;
- Jagust, William J.;
- Johnson, Keith A.;
- Karten, Yashmin;
- Kolb, Hartmuth C.;
- Lopresti, Brian J.
Publication type:
Article
The AHEAD 3‐45 Study: Design of a prevention trial for Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 4, p. 1227, doi. 10.1002/alz.12748
By:
- Rafii, Michael S.;
- Sperling, Reisa A.;
- Donohue, Michael C.;
- Zhou, Jin;
- Roberts, Claire;
- Irizarry, Michael C.;
- Dhadda, Shobha;
- Sethuraman, Gopalan;
- Kramer, Lynn D;
- Swanson, Chad J;
- Li, David;
- Krause, Stephen;
- Rissman, Robert A.;
- Walter, Sarah;
- Raman, Rema;
- Johnson, Keith A.;
- Aisen, Paul S.
Publication type:
Article
Recommendations to address key recruitment challenges of Alzheimer's disease clinical trials.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 2, p. 696, doi. 10.1002/alz.12737
By:
- Langbaum, Jessica B.;
- Zissimopoulos, Julie;
- Au, Rhoda;
- Bose, Niranjan;
- Edgar, Chris J.;
- Ehrenberg, Evan;
- Fillit, Howard;
- Hill, Carl V.;
- Hughes, Lynne;
- Irizarry, Michael;
- Kremen, Sarah;
- Lakdawalla, Darius;
- Lynn, Nancy;
- Malzbender, Kristina;
- Maruyama, Tetsuyuki;
- Massett, Holly A.;
- Patel, Deep;
- Peneva, Desi;
- Reiman, Eric M.;
- Romero, Klaus
Publication type:
Article
Strategies for diverse participant recruitment to a preclinical Alzheimer's Disease prevention trial: The AHEAD study.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 11, p. 1, doi. 10.1002/alz.068222
By:
- Molina‐Henry, Doris P.;
- Grill, Joshua;
- Sperling, Reisa A.;
- Aisen, Paul;
- Clanton, Taylor;
- Devins, Theresa;
- Dhadda, Shobha;
- Glover, Crystal M;
- Irizarry, Michael C;
- Johnson, Keith A.;
- Kirn, Dylan;
- Kramer, Lynn D;
- Shum, Leona K;
- Zhou, Jin;
- Raman, Rema
Publication type:
Article
Diversity in Phase 2 and Phase 3 Placebo‐Controlled, Double‐Blind, Lecanemab and Elenbecestat Early Alzheimer's Disease Studies.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.069198
By:
- Grill, Joshua;
- Molina‐Henry, Doris P.;
- Sperling, Reisa A.;
- Dhadda, Shobha;
- Tranotti, Kate;
- Harris, Russell;
- Devins, Theresa;
- Swanson, Chad J;
- Kanekiyo, Michio;
- Gee, Michelle;
- Irizarry, Michael C;
- Kramer, Lynn D;
- Aisen, Paul;
- Raman, Rema
Publication type:
Article
Neuropathological autopsy findings in an individual with Alzheimer's disease who received long‐term treatment with lecanemab (BAN2401).
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.069220
By:
- Honig, Lawrence S;
- Sun, Yu;
- Irizarry, Michael C;
- Swanson, Chad J;
- Dhadda, Shobha;
- Charil, Arnaud;
- Hart, David E;
- Noble, James M;
- Huey, Edward D;
- Teich, Andrew F
Publication type:
Article
Lecanemab (BAN2401) Infusion Reactions and Immunogenicity: Results from Randomized Phase 2 Study and an Open‐Label Extension (OLE).
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.066289
By:
- Landry, Ishani;
- Kanekiyo, Michio;
- Aluri, Jagadeesh;
- Li, David JianJun;
- Hussein, Ziad;
- Reyderman, Larisa;
- Dhadda, Shobha;
- Swanson, Chad J;
- Irizarry, Michael C;
- Kramer, Lynn D
Publication type:
Article
Development of Clinical Trial Simulation Tools for Alzheimer's Disease through the Critical Path for Alzheimer's Disease (CPAD) Consortium.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.059971
By:
- Sivakumaran, Sudhir;
- Cui, Zihan;
- Priest, Eileen;
- Lau, Corissa;
- White, Hazel;
- Irizarry, Michael C;
- Romero, Klaus;
- Karten, Yashmin
Publication type:
Article
Baseline regional Tau distribution predicts fast cognitive decline in subjects with mild cognitive impairment.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 5, p. 1, doi. 10.1002/alz.068154
By:
- Charil, Arnaud;
- Devanarayan, Viswanath;
- Murali, Leema;
- Qi, Xin;
- Krause, Stephen;
- Sachdev, Pallavi;
- Reyderman, Larisa;
- Koyama, Akihiko;
- Dhadda, Shobha;
- Irizarry, Michael C
Publication type:
Article
Development and validation of AI‐based tools for brain amyloid‐β detection using MRI.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 5, p. 1, doi. 10.1002/alz.068231
By:
- Devanarayan, Viswanath;
- Charil, Arnaud;
- Nelson, Todd;
- Qi, Xin;
- Murali, Leema;
- Reyderman, Larisa;
- Irizarry, Michael C;
- Koyama, Akihiko;
- Dhadda, Shobha
Publication type:
Article
Derivation and evaluation of signatures using plasma β‐amyloid and pTau‐181 for brain amyloid‐β detection.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 5, p. 1, doi. 10.1002/alz.067811
By:
- Devanarayan, Viswanath;
- Dhadda, Shobha;
- Koyama, Akihiko;
- Swanson, Chad J;
- Hampel, Harald;
- Irizarry, Michael C;
- Kramer, Lynn D
Publication type:
Article
Preliminary assessment of the clinical effects of lecanemab following 18 months of treatment in the open label extension of the phase 2 proof of concept study, BAN2401‐G000‐201, in subjects with early Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.057780
By:
- Swanson, Chad J;
- Dhadda, Shobha;
- Irizarry, Michael C;
- Kanekiyo, Michio;
- Li, David JianJun;
- Kaplow, June;
- Gordon, Robert;
- Heanue‐Travers, Helena;
- Hodgkinson, Mark;
- Kramer, Lynn D
Publication type:
Article
Plasma Aβ 42:40 ratio tracks with changes in brain amyloid PET SUVr in the core and open label extension of the phase 2 proof of concept study ban2401‐g000‐201 following treatment with lecanemab in subjects with early Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.057760
By:
- Swanson, Chad J;
- Kanekiyo, Michio;
- Kaplow, June;
- Dhadda, Shobha;
- Irizarry, Michael C;
- Koyama, Akihiko;
- Li, David JianJun;
- Verbel, David;
- Gordon, Robert;
- Heanue‐Travers, Helena;
- Hodgkinson, Mark;
- Kramer, Lynn D
Publication type:
Article
Baseline characteristics for CLARITY AD: A phase 3 placebo‐controlled, double‐blind, parallel‐group, 18‐month study evaluating lecanemab (ban2401) in early Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.054331
By:
- Lynch, Shau Yu;
- Irizarry, Michael C;
- Dhadda, Shobha;
- Li, David JianJun;
- Kanekiyo, Michio;
- Bogoslovsky, Tanya;
- Gee, Michelle;
- Reyderman, Larisa;
- Kaplow, June;
- Rabe, Martin;
- Hodgkinson, Mark;
- Kramer, Lynn D;
- Hampel, Harald;
- Swanson, Chad J
Publication type:
Article
AHEAD 3‐45 study: Preliminary screening and baseline characteristics from a placebo‐controlled, double‐blind study evaluating lecanemab in participants with preclinical Alzheimer's disease and elevated (A45 trial) and intermediate (A3 trial) amyloid
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.053143
By:
- Zhou, Jin;
- Irizarry, Michael C;
- Kramer, Lynn D;
- Swanson, Chad J;
- Roberts, Claire;
- Dhadda, Shobha;
- Li, David JianJun;
- Rabe, Martin;
- Krause, Stephen;
- Raman, Rema;
- Donohue, Michael C;
- Sethuraman, Gopalan;
- Johnson, Keith A.;
- Sperling, Reisa A.;
- Aisen, Paul S
Publication type:
Article
The design of Dominantly Inherited Alzheimer Disease Trial of the anti‐tau antibody, E‐2814, on the DIAN‐TU Tau Next Generation Platform.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.057320
By:
- Schneider, Lon S.;
- Bateman, Randall J.;
- Clifford, David B.;
- McDade, Eric;
- Wang, Guoqiao;
- Llibre‐Guerra, Jorge J.;
- Li, Yan;
- Mills, Susan;
- Santacruz, Anna;
- Sachdev, Pallavi;
- Li, David JianJun;
- O'Sullivan, Stacie;
- Yagi, Takuya;
- Koyama, Akihiko;
- Irizarry, Michael C.;
- Reyderman, Larisa
Publication type:
Article
Initial exploration of a brain age score based on validated computerized cognitive assessments in Japanese individuals: Neuropsychology/Multicultural issues in assessment of dementia.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 6, p. 1, doi. 10.1002/alz.045446
By:
- Edgar, Chris J.;
- Schembri, Adrian;
- Maruff, Paul T.;
- Gee, Michelle;
- Iwatsubo, Takeshi;
- Aisen, Paul S.;
- Sperling, Reisa A.;
- Irizarry, Michael C.
Publication type:
Article
Initial exploration of a brain age score based on validated computerized cognitive assessments in Japanese individuals: Neuropsychology/Multicultural issues in assessment of dementia.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.045446
By:
- Edgar, Chris J.;
- Schembri, Adrian;
- Maruff, Paul T.;
- Gee, Michelle;
- Iwatsubo, Takeshi;
- Aisen, Paul S.;
- Sperling, Reisa A.;
- Irizarry, Michael C.
Publication type:
Article
AHEAD 3‐45 study design: A global study to evaluate the efficacy and safety of treatment with BAN2401 for 216 weeks in preclinical Alzheimer's disease with intermediate amyloid (A3 trial) and elevated amyloid (A45 trial): Clinical trial design and implementation
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.044511
By:
- Aisen, Paul S.;
- Zhou, Jin;
- Irizarry, Michael C.;
- Kramer, Lynn D;
- Swanson, Chad J.;
- Dhadda, Shobha;
- Rabe, Martin;
- Krause, Stephen;
- Li, David JianJun;
- Raman, Rema;
- Donohue, Michael C.;
- Sethuraman, Gopalan;
- Johnson, Keith A.;
- Sperling, Reisa A.
Publication type:
Article
New directions in clinical trials for frontotemporal lobar degeneration: Methods and outcome measures.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 1, p. 131, doi. 10.1016/j.jalz.2019.06.4956
By:
- Boxer, Adam L.;
- Gold, Michael;
- Feldman, Howard;
- Boeve, Bradley F.;
- Dickinson, Susan L.-J.;
- Fillit, Howard;
- Ho, Carole;
- Paul, Robert;
- Pearlman, Rodney;
- Sutherland, Margaret;
- Verma, Ajay;
- Arneric, Stephen P.;
- Alexander, Brian M.;
- Dickerson, Bradford C.;
- Dorsey, Earl Ray;
- Grossman, Murray;
- Huey, Edward D.;
- Irizarry, Michael C.;
- Marks, William J.;
- Masellis, Mario
Publication type:
Article
DT‐01‐01: BAN2401 IN EARLY ALZHEIMER'S DISEASE: NEURODEGENERATION BIOMARKER ANALYSIS FROM A RANDOMIZED PHASE 2 STUDY.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1484, doi. 10.1016/j.jalz.2019.08.004
By:
- Molinuevo, Jose Luis;
- Koyama, Akihiko;
- Dhadda, Shobha;
- Irizarry, Michael C.;
- Swanson, Chad J.;
- Zhang, Yong;
- Kaplow, June;
- Bradley, Heather;
- Rabe, Martin;
- Totsuka, Keiichiro;
- Lai, Robert YK.;
- Gordon, Robert;
- Kramer, Lynn D.
Publication type:
Article
P1‐048: PLASMA NF‐L AS A BIOMARKER FOR NEURODEGENERATION IN MILD AD SUBJECTS IN THE PHASE 2 NAVIGATE‐AD STUDY.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P251, doi. 10.1016/j.jalz.2019.06.073
By:
- Wang, Hong;
- Charil, Arnaud;
- Shcherbinin, Sergey;
- Natanegara, Fanni;
- Chao, Georgia;
- Evans, Cynthia Duggan;
- Dage, Jeffrey;
- Irizarry, Michael C.;
- Lo, Albert;
- Sims, John R.
Publication type:
Article
P4‐388: TRAILBLAZER‐ALZ (NCT03367403): A PHASE 2 DISEASE‐MODIFICATION COMBINATION THERAPY TRIAL TARGETING MULTIPLE MECHANISMS OF ACTION ALONG THE AMYLOID PATHWAY.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1622, doi. 10.1016/j.jalz.2018.07.212
By:
- Irizarry, Michael C.;
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- Hake, Ann Marie;
- Liu, Peng;
- Shcherbinin, Sergey;
- DeMattos, Ronald B.;
- Mintun, Mark A.
Publication type:
Article
O3‐13‐02: LOBAR CLASSIFICATION OF TAU PET IMAGES IN THE EXPEDITION‐3 TRIAL.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1055, doi. 10.1016/j.jalz.2018.06.2844
By:
- Shcherbinin, Sergey;
- Liu, Peng;
- Fleisher, Adam S.;
- Sundell, Karen L.;
- Charil, Arnaud;
- Lu, Ming;
- Devous, Michael D.;
- Pontecorvo, Michael J.;
- Mintun, Mark A.;
- Siemers, Eric R.;
- Irizarry, Michael C.;
- Schwarz, Adam J.
Publication type:
Article
P1‐326: THE USE OF THE DIGITAL CLOCK DRAWING TEST (DCTCLOCK™) IN THE SCREENING PHASE OF CLINICAL TRIALS FOR ALZHEIMER'S DISEASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P416, doi. 10.1016/j.jalz.2018.06.333
By:
- Dage, Jeffrey L.;
- Battioui, Chakib;
- Wang, Jian WJ.;
- Charil, Arnaud;
- Shcherbinin, Sergey;
- Lowe, Stephen L.;
- Lo, Albert;
- Cleverly, Ann L.;
- Schwarz, Adam J.;
- Irizarry, Michael C.;
- Miller, Bradley B.
Publication type:
Article
O1‐09‐01: SIGNIFICANT AND SUSTAINED FLORBETAPIR F18 UPTAKE REDUCTION IN PATIENTS WITH SYMPTOMATIC ALZHEIMER'S DISEASE WITH LY3002813, A β‐AMYLOID PLAQUE‐SPECIFIC ANTIBODY.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P239, doi. 10.1016/j.jalz.2018.06.2378
By:
- Fleisher, Adam S.;
- Lowe, Stephen L.;
- Liu, Peng;
- Shcherbinin, Sergey;
- Li, Li;
- Chua, Laiyi;
- Nakano, Masako;
- Hawdon, Anne;
- Willis, Brian A.;
- Schwarz, Adam J.;
- Demattos, Ronald B.;
- Mintun, Mark A.;
- Irizarry, Michael C.
Publication type:
Article
IC‐P‐216: LOBAR CLASSIFICATION OF TAU PET IMAGES IN THE EXPEDITION‐3 TRIAL.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P177, doi. 10.1016/j.jalz.2018.06.2283
By:
- Shcherbinin, Sergey;
- Liu, Peng;
- Fleisher, Adam S.;
- Sundell, Karen L.;
- Charil, Arnaud;
- Lu, Ming;
- Devous, Michael D.;
- Pontecorvo, Michael J.;
- Mintun, Mark A.;
- Siemers, Eric R.;
- Irizarry, Michael C.;
- Schwarz, Adam J.
Publication type:
Article
Sudden unexpected death in epilepsy in lamotrigine randomized-controlled trials.
Published in:
Epilepsia (Series 4), 2013, v. 54, n. 1, p. 135, doi. 10.1111/j.1528-1167.2012.03689.x
By:
- Tomson, Torbjörn;
- Hirsch, Lawrence J.;
- Friedman, Daniel;
- Bester, Nicolette;
- Hammer, Anne;
- Irizarry, Michael;
- Ishihara, Lianna;
- Krishen, Alok;
- Spaulding, Theodore;
- Wamil, Art;
- Leadbetter, Robert
Publication type:
Article
Challenges and opportunities for improving the landscape for Lewy body dementia clinical trials.
Published in:
Alzheimer's Research & Therapy, 2020, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13195-020-00703-5
By:
- Goldman, Jennifer G.;
- Forsberg, Leah K.;
- Boeve, Bradley F.;
- Armstrong, Melissa J.;
- Irwin, David J.;
- Ferman, Tanis J.;
- Galasko, Doug;
- Galvin, James E.;
- Kaufer, Daniel;
- Leverenz, James;
- Lippa, Carol F.;
- Marder, Karen;
- Abler, Victor;
- Biglan, Kevin;
- Irizarry, Michael;
- Keller, Bill;
- Munsie, Leanne;
- Nakagawa, Masaki;
- Taylor, Angela;
- Graham, Todd
Publication type:
Article
Secondary prevention of Alzheimer's dementia: neuroimaging contributions.
Published in:
Alzheimer's Research & Therapy, 2018, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13195-018-0438-z
By:
- ten Kate, Mara;
- Ingala, Silvia;
- Schwarz, Adam J.;
- Fox, Nick C.;
- Chételat, Gaël;
- van Berckel, Bart N. M.;
- Ewers, Michael;
- Foley, Christopher;
- Gispert, Juan Domingo;
- Hill, Derek;
- Irizarry, Michael C.;
- Lammertsma, Adriaan A.;
- Molinuevo, José Luis;
- Ritchie, Craig;
- Scheltens, Philip;
- Schmidt, Mark E.;
- Visser, Pieter Jelle;
- Waldman, Adam;
- Wardlaw, Joanna;
- Haller, Sven
Publication type:
Article
An exploration of cognitive subgroups in Alzheimer's disease.
Published in:
Journal of the International Neuropsychological Society, 2010, v. 16, n. 2, p. 233, doi. 10.1017/S1355617709991160
By:
- Davidson, Julie E.;
- Irizarry, Michael C.;
- Bray, Bethany C.;
- Wetten, Sally;
- Galwey, Nicholas;
- Gibson, Rachel;
- Borrie, Michael;
- Delisle, Richard;
- Feldman, Howard H.;
- Ging-Yuek Hsiung;
- Fornazzari, Luis;
- Gauthier, Serge;
- Guzman, Danilo;
- Loy-English, Inge;
- Keren, Ron;
- Kertesz, Andrew;
- St. George-Hyslop, Peter;
- Wherrett, John;
- Monsch, Andreas U.
Publication type:
Article

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