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A novel dual PPAR-γ agonist/sEH inhibitor treats diabetic complications in a rat model of type 2 diabetes.
- Published in:
- Diabetologia, 2018, v. 61, n. 10, p. 2235, doi. 10.1007/s00125-018-4685-0
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- Publication type:
- Article
Replacement of Lost Substance P Reduces Fibrosis in the Diabetic Heart by Preventing Adverse Fibroblast and Macrophage Phenotype Changes.
- Published in:
- Cells (2073-4409), 2021, v. 10, n. 10, p. 2659, doi. 10.3390/cells10102659
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- Publication type:
- Article
Epoxyeicosatrienoic Acid Analog Decreases Renal Fibrosis by Reducing Epithelial-to-Mesenchymal Transition.
- Published in:
- Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00406
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- Publication type:
- Article
Carbonylation Modification Regulates Na/K-ATPase Signaling and Salt Sensitivity: A Review and a Hypothesis.
- Published in:
- Frontiers in Physiology, 2016, p. 1, doi. 10.3389/fphys.2016.00256
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- Publication type:
- Article
Soluble epoxide hydrolase inhibition and peroxisome proliferator activated receptor γ agonist improve vascular function and decrease renal injury in hypertensive obese rats.
- Published in:
- Experimental Biology & Medicine, 2012, v. 237, n. 12, p. 1402, doi. 10.1258/ebm.2012.012225
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- Publication type:
- Article
Novel orally active epoxyeicosatrienoic acid (EET) analogs attenuate cisplatin nephrotoxicity.
- Published in:
- FASEB Journal, 2013, v. 27, n. 8, p. 2946, doi. 10.1096/fj.12-218040
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- Publication type:
- Article
Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice.
- Published in:
- FASEB Journal, 2010, v. 24, n. 10, p. 3770, doi. 10.1096/fj.10-160119
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- Publication type:
- Article
Increased blood pressure in mice lacking cytochrome P450 2J5.
- Published in:
- FASEB Journal, 2008, v. 22, n. 12, p. 4096, doi. 10.1096/fj.08-114413
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- Publication type:
- Article
557 Dual TGFβR1/MAP4K4 inhibitor reduces kidney injury in a mouse model of renal fibrosis.
- Published in:
- 2024
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- Publication type:
- Abstract
Different mechanisms of acute versus long-term antihypertensive effects of soluble epoxide hydrolase inhibition: Studies in Cyp1a1-Ren-2 transgenic rats.
- Published in:
- Clinical & Experimental Pharmacology & Physiology, 2014, v. 41, n. 12, p. 1003, doi. 10.1111/1440-1681.12310
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- Publication type:
- Article
Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats.
- Published in:
- Clinical & Experimental Pharmacology & Physiology, 2014, v. 41, n. 3, p. 227, doi. 10.1111/1440-1681.12204
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- Publication type:
- Article
Antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats is mediated by suppression of the intrarenal renin-angiotensin system.
- Published in:
- Clinical & Experimental Pharmacology & Physiology, 2013, v. 40, n. 4, p. 273, doi. 10.1111/1440-1681.12018
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- Publication type:
- Article
Captopril attenuates hypertension and renal injury induced by the vascular endothelial growth factor inhibitor sorafenib.
- Published in:
- Clinical & Experimental Pharmacology & Physiology, 2012, v. 39, n. 5, p. 454, doi. 10.1111/j.1440-1681.2012.05699.x
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- Publication type:
- Article
Peroxisome proliferator-activated receptors, farnesoid X receptor, and dual modulating drugs in hypertension.
- Published in:
- Frontiers in Physiology, 2023, p. 1, doi. 10.3389/fphys.2023.1186477
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- Publication type:
- Article
Editorial: The future of physiology: 2020 and beyond, Volume III.
- Published in:
- Frontiers in Physiology, 2023, v. 14, p. 1, doi. 10.3389/fphys.2023.1159406
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- Publication type:
- Article
Frontiers in metabolic physiology grand challenges.
- Published in:
- Frontiers in Physiology, 2022, v. 13, p. 01, doi. 10.3389/fphys.2022.879617
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- Publication type:
- Article
Epoxygenase Metabolites Contribute to Nitric Oxide-Independent Afferent Arteriolar Vasodilation in Response to Bradykinin.
- Published in:
- Journal of Vascular Research, 2001, v. 38, n. 3, p. 247, doi. 10.1159/000051053
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- Publication type:
- Article
Role of Cytochrome P-450 in Elevating Renal Vascular Tone in Spontaneously Hypertensive Rats.
- Published in:
- Journal of Vascular Research, 1993, v. 30, n. 1, p. 53, doi. 10.1159/000158975
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- Publication type:
- Article
Inactivation of p66Shc Decreases Afferent Arteriolar K<sub>ATP</sub> Channel Activity and Decreases Renal Damage in Diabetic Dahl SS Rats.
- Published in:
- 2018
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- Publication type:
- journal article
Kidney-Targeted Epoxyeicosatrienoic Acid Analog, EET-F01, Reduces Inflammation, Oxidative Stress, and Cisplatin-Induced Nephrotoxicity.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 6, p. 2793, doi. 10.3390/ijms22062793
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- Publication type:
- Article
Novel Omega-3 Fatty Acid Epoxygenase Metabolite Reduces Kidney Fibrosis.
- Published in:
- International Journal of Molecular Sciences, 2016, v. 17, n. 5, p. 751, doi. 10.3390/ijms17050751
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- Publication type:
- Article
OBESITY INDUCED RENAL OXIDATIVE STRESS CONTRIBUTES TO RENAL INJURY IN SALT-SENSITIVE HYPERTENSION.
- Published in:
- Clinical & Experimental Pharmacology & Physiology, 2009, v. 36, n. 7, p. 724, doi. 10.1111/j.1440-1681.2009.05139.x
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- Publication type:
- Article
Editorial: Nuclear receptors in hemodynamics and blood pressure control.
- Published in:
- Frontiers in Physiology, 2023, p. 01, doi. 10.3389/fphys.2023.1290411
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- Publication type:
- Article
Role of the cytochrome P-450/ epoxyeicosatrienoic acids pathway in the pathogenesis of renal dysfunction in cirrhosis.
- Published in:
- Nephrology Dialysis Transplantation, 2018, v. 33, n. 8, p. 1333, doi. 10.1093/ndt/gfx354
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- Publication type:
- Article
Altered Kidney CYP2C and Cyclooxygenase-2 Levels Are Associated with Obesity-Related Albuminuria<sup>**</sup>.
- Published in:
- Obesity (19307381), 2004, v. 12, n. 8, p. 1278, doi. 10.1038/oby.2004.162
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- Publication type:
- Article
Epoxyeicosatrienoic Acid Analog EET-A Blunts Development of Lupus Nephritis in Mice.
- Published in:
- Frontiers in Pharmacology, 2019, p. N.PAG, doi. 10.3389/fphar.2019.00512
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- Publication type:
- Article
Epoxyeicosatrienoic Acid-Based Therapy Attenuates the Progression of Postischemic Heart Failure in Normotensive Sprague-Dawley but Not in Hypertensive Ren-2 Transgenic Rats.
- Published in:
- Frontiers in Pharmacology, 2019, p. N.PAG, doi. 10.3389/fphar.2019.00159
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- Publication type:
- Article
Azilsartan Improves Glycemic Status and Reduces Kidney Damage in Zucker Diabetic Fatty Rats.
- Published in:
- American Journal of Hypertension, 2014, v. 27, n. 8, p. 1087, doi. 10.1093/ajh/hpu016
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- Publication type:
- Article
Telmisartan Provides Better Renal Protection Than Valsartan in a Rat Model of Metabolic Syndrome.
- Published in:
- American Journal of Hypertension, 2011, v. 24, n. 7, p. 816, doi. 10.1038/ajh.2011.34
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- Publication type:
- Article
Afferent arteriolar reactivity to angiotensin II is enhanced during the early phase of angiotensin II hypertension<sup>*</sup>.
- Published in:
- American Journal of Hypertension, 2000, v. 13, n. 7, p. 810, doi. 10.1016/S0895-7061(00)00264-8
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- Publication type:
- Article
Renal responses to AT<sub>1</sub> receptor blockade.
- Published in:
- American Journal of Hypertension, 2000, v. 13, p. 45S, doi. 10.1016/S0895-7061(99)00248-4
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- Publication type:
- Article
Renal Uptake of Circulating Angiotensin II in Val<sup>5</sup>-Angiotensin II Infused Rats Is Mediated by AT<sub>1</sub> Receptor<sup>*</sup>.
- Published in:
- American Journal of Hypertension, 1998, v. 11, n. 5, p. 570, doi. 10.1016/S0895-7061(97)00410-X
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- Publication type:
- Article
Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension.
- Published in:
- Journal of Physiology, 2011, v. 589, n. 1, p. 207, doi. 10.1113/jphysiol.2010.199505
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- Publication type:
- Article
Regulation of Cardiac Mast Cell Maturation and Function by the Neurokinin-1 Receptor in the Fibrotic Heart.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-47369-0
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- Publication type:
- Article
Kidney Injury by Unilateral Ureteral Obstruction in Mice Lacks Sex Differences.
- Published in:
- Kidney & Blood Pressure Research, 2024, v. 49, n. 1, p. 69, doi. 10.1159/000535809
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- Publication type:
- Article
Multi-Target Approaches in Metabolic Syndrome.
- Published in:
- Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.554961
- By:
- Publication type:
- Article
Editorial: Clinical Paths for Soluble Epoxide Hydrolase Inhibitors.
- Published in:
- 2020
- By:
- Publication type:
- Editorial
ETA and ETB receptors differentially modulate afferent and efferent arteriolar responses to endothelin.
- Published in:
- 2005
- By:
- Publication type:
- journal article
Contribution of cytochrome P450 epoxygenase and hydroxylase pathways to afferent arteriolar autoregulatory responsiveness.
- Published in:
- 1999
- By:
- Publication type:
- journal article
Editorial: Interactions Between Podocytes, Mesangial Cells, and Glomerular Endothelial Cells in Glomerular Diseases.
- Published in:
- 2022
- By:
- Publication type:
- Editorial
Regulation of ENaC-Mediated Sodium Reabsorption by Peroxisome Proliferator-Activated Receptors.
- Published in:
- PPAR Research, 2010, p. 1, doi. 10.1155/2010/703735
- By:
- Publication type:
- Article
p66Shc regulates renal vascular tone in hypertension-induced nephropathy.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Antihypertensive effects of selective prostaglandin E2 receptor subtype 1 targeting.
- Published in:
- 2007
- By:
- Publication type:
- journal article
Epoxyeicosatrienoic Acid Analog and 20-HETE Antagonist Combination Prevent Hypertension Development in Spontaneously Hypertensive Rats.
- Published in:
- Frontiers in Pharmacology, 2022, v. 12, p. 1, doi. 10.3389/fphar.2021.798642
- By:
- Publication type:
- Article
Dual sEH/COX-2 Inhibition Using PTUPB—A Promising Approach to Antiangiogenesis-Induced Nephrotoxicity.
- Published in:
- Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.744776
- By:
- Publication type:
- Article
Afferent Arteriolar Dilation to 11, 12-EET Analogs Involves PP2A Activity and Ca2 +-Activated K+ Channels.
- Published in:
- Microcirculation, 2008, v. 15, n. 2, p. 137, doi. 10.1080/10739680701456960
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- Publication type:
- Article
Obesity, Insulin Resistance, and Renal Function.
- Published in:
- Microcirculation, 2007, v. 14, n. 4/5, p. 349, doi. 10.1080/10739680701283018
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- Publication type:
- Article
Adaptations of the Renal Microcirculation to Hypertension.
- Published in:
- Microcirculation, 2002, v. 9, n. 4, p. 315, doi. 10.1080/mic.9.4.315.328
- By:
- Publication type:
- Article
Early Renal Vasodilator and Hypotensive Action of Epoxyeicosatrienoic Acid Analog (EET-A) and 20-HETE Receptor Blocker (AAA) in Spontaneously Hypertensive Rats.
- Published in:
- Frontiers in Physiology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphys.2021.622882
- By:
- Publication type:
- Article
Editorial: Renal Function in Acute and Chronic Kidney Diseases.
- Published in:
- 2020
- By:
- Publication type:
- Editorial