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Diagnostic efficiency of whole-body 18F-FDG PET/MRI, MRI alone, and SUV and ADC values in staging of primary uterine cervical cancer.
Published in:
2021
By:
- Steiner, Aida;
- Narva, Sara;
- Rinta-Kiikka, Irina;
- Hietanen, Sakari;
- Hynninen, Johanna;
- Virtanen, Johanna
Publication type:
journal article
Behavior of FDG-avid supradiaphragmatic lymph nodes in PET/CT throughout primary therapy in advanced serous epithelial ovarian cancer: a prospective study.
Published in:
2019
By:
- Laasik, Maren;
- Kemppainen, Jukka;
- Auranen, Annika;
- Hietanen, Sakari;
- Grénman, Seija;
- Seppänen, Marko;
- Hynninen, Johanna
Publication type:
journal article
ALDH1A1‐related stemness in high‐grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR‐PI3K/aurora kinase inhibitors.
Published in:
Journal of Pathology, 2020, v. 250, n. 2, p. 159, doi. 10.1002/path.5356
By:
- Kaipio, Katja;
- Chen, Ping;
- Roering, Pia;
- Huhtinen, Kaisa;
- Mikkonen, Piia;
- Östling, Päivi;
- Lehtinen, Laura;
- Mansuri, Naziha;
- Korpela, Taina;
- Potdar, Swapnil;
- Hynninen, Johanna;
- Auranen, Annika;
- Grénman, Seija;
- Wennerberg, Krister;
- Hautaniemi, Sampsa;
- Carpén, Olli
Publication type:
Article
Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24009-8
By:
- Pietilä, Elina A.;
- Gonzalez-Molina, Jordi;
- Moyano-Galceran, Lidia;
- Jamalzadeh, Sanaz;
- Zhang, Kaiyang;
- Lehtinen, Laura;
- Turunen, S. Pauliina;
- Martins, Tomás A.;
- Gultekin, Okan;
- Lamminen, Tarja;
- Kaipio, Katja;
- Joneborg, Ulrika;
- Hynninen, Johanna;
- Hietanen, Sakari;
- Grénman, Seija;
- Lehtonen, Rainer;
- Hautaniemi, Sampsa;
- Carpén, Olli;
- Carlson, Joseph W.;
- Lehti, Kaisa
Publication type:
Article
FUNGI: FUsioN Gene Integration toolset.
Published in:
Bioinformatics, 2021, v. 37, n. 19, p. 3353, doi. 10.1093/bioinformatics/btab206
By:
- Cervera, Alejandra;
- Rausio, Heidi;
- Kähkönen, Tiia;
- Andersson, Noora;
- Partel, Gabriele;
- Rantanen, Ville;
- Paciello, Giulia;
- Ficarra, Elisa;
- Hynninen, Johanna;
- Hietanen, Sakari;
- Carpén, Olli;
- Lehtonen, Rainer;
- Hautaniemi, Sampsa;
- Huhtinen, Kaisa
Publication type:
Article
PRISM: recovering cell-type-specific expression profiles from individual composite RNA-seq samples.
Published in:
Bioinformatics, 2021, v. 37, n. 18, p. 2882, doi. 10.1093/bioinformatics/btab178
By:
- Häkkinen, Antti;
- Zhang, Kaiyang;
- Alkodsi, Amjad;
- Andersson, Noora;
- Erkan, Erdogan Pekcan;
- Dai, Jun;
- Kaipio, Katja;
- Lamminen, Tarja;
- Mansuri, Naziha;
- Huhtinen, Kaisa;
- Vähärautio, Anna;
- Carpén, Olli;
- Hynninen, Johanna;
- Hietanen, Sakari;
- Lehtonen, Rainer;
- Hautaniemi, Sampsa
Publication type:
Article
Genome-wide quantification of copy-number aberration impact on gene expression in ovarian high-grade serous carcinoma.
Published in:
BMC Cancer, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12885-024-11895-6
By:
- Jamalzadeh, Sanaz;
- Dai, Jun;
- Lavikka, Kari;
- Li, Yilin;
- Jiang, Jing;
- Huhtinen, Kaisa;
- Virtanen, Anni;
- Oikkonen, Jaana;
- Hietanen, Sakari;
- Hynninen, Johanna;
- Vähärautio, Anna;
- Häkkinen, Antti;
- Hautaniemi, Sampsa
Publication type:
Article
Genome-wide quantification of copy-number aberration impact on gene expression in ovarian high-grade serous carcinoma.
Published in:
BMC Cancer, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12885-024-11895-6
By:
- Jamalzadeh, Sanaz;
- Dai, Jun;
- Lavikka, Kari;
- Li, Yilin;
- Jiang, Jing;
- Huhtinen, Kaisa;
- Virtanen, Anni;
- Oikkonen, Jaana;
- Hietanen, Sakari;
- Hynninen, Johanna;
- Vähärautio, Anna;
- Häkkinen, Antti;
- Hautaniemi, Sampsa
Publication type:
Article
A Subset of Secreted Proteins in Ascites Can Predict Platinum-Free Interval in Ovarian Cancer.
Published in:
Cancers, 2022, v. 14, n. 17, p. 4291, doi. 10.3390/cancers14174291
By:
- Carroll, Molly J.;
- Kaipio, Katja;
- Hynninen, Johanna;
- Carpen, Olli;
- Hautaniemi, Sampsa;
- Page, David;
- Kreeger, Pamela K.
Publication type:
Article
A Novel Two-Lipid Signature Is a Strong and Independent Prognostic Factor in Ovarian Cancer.
Published in:
Cancers, 2021, v. 13, n. 8, p. 1764, doi. 10.3390/cancers13081764
By:
- Salminen, Liina;
- Braicu, Elena Ioana;
- Lääperi, Mitja;
- Jylhä, Antti;
- Oksa, Sinikka;
- Hietanen, Sakari;
- Sehouli, Jalid;
- Kulbe, Hagen;
- Bois, Andreas du;
- Mahner, Sven;
- Harter, Philipp;
- Carpén, Olli;
- Huhtinen, Kaisa;
- Hynninen, Johanna;
- Hilvo, Mika;
- Bianchi, Fabrizio
Publication type:
Article
Exploratory Analysis of CA125-MGL and --STn Glycoforms in the Differential Diagnostics of Pelvic Masses.
Published in:
Journal of Applied Laboratory Medicine, 2020, v. 5, n. 2, p. 263, doi. 10.1093/jalm/jfz012
By:
- Salminen, Liina;
- Nadeem, Nimrah;
- Rolfsen, Anne Lone;
- Dørum, Anne;
- Laajala, Teemu D.;
- Grènman, Seija;
- Hietanen, Sakari;
- Heinosalo, Taija;
- Perheentupa, Antti;
- Poutanen, Matti;
- Bolstad, Nils;
- Carpén, Olli;
- Lamminmäki, Urpo;
- Pettersson, Kim;
- Gidwani, Kamlesh;
- Hynninen, Johanna;
- Huhtinen, Kaisa
Publication type:
Article
Europium Nanoparticle-Based Sialyl-Tn Monoclonal Antibody Discriminates Epithelial Ovarian Cancer--Associated CA125 from Benign Sources.
Published in:
Journal of Applied Laboratory Medicine, 2019, p. 299, doi. 10.1373/jalm.2018.028266
By:
- Gidwani, Kamlesh;
- Nadeem, Nimrah;
- Huhtinen, Kaisa;
- Kekki, Henna;
- Heinosalo, Taija;
- Hynninen, Johanna;
- Perheentupa, Antti;
- Poutanen, Matti;
- Carpen, Olli;
- Pettersson, Kim;
- Lamminmäki, Urpo
Publication type:
Article
Glycovariant-based lateral flow immunoassay to detect ovarian cancer–associated serum CA125.
Published in:
Communications Biology, 2020, v. 3, n. 1, p. N.PAG, doi. 10.1038/s42003-020-01191-x
By:
- Bayoumy, Sherif;
- Hyytiä, Heidi;
- Leivo, Janne;
- Talha, Sheikh M.;
- Huhtinen, Kaisa;
- Poutanen, Matti;
- Hynninen, Johanna;
- Perheentupa, Antti;
- Lamminmäki, Urpo;
- Gidwani, Kamlesh;
- Pettersson, Kim
Publication type:
Article
Virtual clinical trials identify effective combination therapies in ovarian cancer.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-55068-z
By:
- Kozłowska, Emilia;
- Vallius, Tuulia;
- Hynninen, Johanna;
- Hietanen, Sakari;
- Färkkilä, Anniina;
- Hautaniemi, Sampsa
Publication type:
Article
The feasibility of [18F]EF5-PET/CT to image hypoxia in ovarian tumors: a clinical study.
Published in:
EJNMMI Research, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13550-020-00689-z
By:
- Laasik, Maren;
- Hynninen, Johanna;
- Forsback, Sarita;
- Noponen, Tommi;
- Seppänen, Marko;
- Hietanen, Sakari
Publication type:
Article
A Nanoparticle-Lectin Immunoassay Improves Discrimination of Serum CA125 from Malignant and Benign Sources.
Published in:
Clinical Chemistry, 2016, v. 62, n. 10, p. 1390, doi. 10.1373/clinchem.2016.257691
By:
- Gidwani, Kamlesh;
- Huhtinen, Kaisa;
- Kekki, Henna;
- van Vliet, Sandra;
- Hynninen, Johanna;
- Koivuviita, Niina;
- Perheentupa, Antti;
- Poutanen, Matti;
- Auranen, Annika;
- Grenman, Seija;
- Lamminmäki, Urpo;
- Carpen, Olli;
- van Kooyk, Yvette;
- Pettersson, Kim
Publication type:
Article
Network-guided identification of cancer-selective combinatorial therapies in ovarian cancer.
Published in:
Briefings in Bioinformatics, 2021, v. 22, n. 6, p. 1, doi. 10.1093/bib/bbab272
By:
- He, Liye;
- Bulanova, Daria;
- Oikkonen, Jaana;
- Häkkinen, Antti;
- Zhang, Kaiyang;
- Zheng, Shuyu;
- Wang, Wenyu;
- Erkan, Erdogan Pekcan;
- Carpén, Olli;
- Joutsiniemi, Titta;
- Hietanen, Sakari;
- Hynninen, Johanna;
- Huhtinen, Kaisa;
- Hautaniemi, Sampsa;
- Vähärautio, Anna;
- Tang, Jing;
- Wennerberg, Krister;
- Aittokallio, Tero
Publication type:
Article
Aggressive and recurrent ovarian cancers upregulate ephrinA5, a non-canonical effector of EphA2 signaling duality.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-88382-6
By:
- Jukonen, Joonas;
- Moyano-Galceran, Lidia;
- Höpfner, Katrin;
- Pietilä, Elina A.;
- Lehtinen, Laura;
- Huhtinen, Kaisa;
- Gucciardo, Erika;
- Hynninen, Johanna;
- Hietanen, Sakari;
- Grénman, Seija;
- Ojala, Päivi M.;
- Carpén, Olli;
- Lehti, Kaisa
Publication type:
Article
Author Correction: Virtual clinical trials identify effective combination therapies in ovarian cancer.
Published in:
2020
By:
- Kozłowska, Emilia;
- Vallius, Tuulia;
- Hynninen, Johanna;
- Hietanen, Sakari;
- Färkkilä, Anniina;
- Hautaniemi, Sampsa
Publication type:
Correction Notice
REG4 Is Highly Expressed in Mucinous Ovarian Cancer: A Potential Novel Serum Biomarker.
Published in:
PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0151590
By:
- Lehtinen, Laura;
- Vesterkvist, Pia;
- Roering, Pia;
- Korpela, Taina;
- Hattara, Liisa;
- Kaipio, Katja;
- Mpindi, John-Patrick;
- Hynninen, Johanna;
- Auranen, Annika;
- Davidson, Ben;
- Haglund, Caj;
- Iljin, Kristiina;
- Grenman, Seija;
- Siitari, Harri;
- Carpen, Olli
Publication type:
Article
Optimized detection of homologous recombination deficiency improves the prediction of clinical outcomes in cancer.
Published in:
NPJ Precision Oncology, 2022, v. 6, n. 1, p. 1, doi. 10.1038/s41698-022-00339-8
By:
- Perez-Villatoro, Fernando;
- Oikkonen, Jaana;
- Casado, Julia;
- Chernenko, Anastasiya;
- Gulhan, Doga C.;
- Tumiati, Manuela;
- Li, Yilin;
- Lavikka, Kari;
- Hietanen, Sakari;
- Hynninen, Johanna;
- Haltia, Ulla-Maija;
- Tyrmi, Jaakko S.;
- Laivuori, Hannele;
- Konstantinopoulos, Panagiotis A.;
- Hautaniemi, Sampsa;
- Kauppi, Liisa;
- Färkkilä, Anniina
Publication type:
Article
HE4 in the evaluation of tumor load and prognostic stratification of high grade serous ovarian carcinoma.
Published in:
Acta Oncologica, 2020, v. 59, n. 12, p. 1461, doi. 10.1080/0284186X.2020.1827157
By:
- Salminen, Liina;
- Gidwani, Kamlesh;
- Grènman, Seija;
- Carpén, Olli;
- Hietanen, Sakari;
- Pettersson, Kim;
- Huhtinen, Kaisa;
- Hynninen, Johanna
Publication type:
Article
Effects of Wee1 inhibitor adavosertib on patient-derived high-grade serous ovarian cancer cells are multiple and independent of homologous recombination status.
Published in:
Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.954430
By:
- Roering, Pia;
- Siddiqui, Arafat;
- Heuser, Vanina D.;
- Potdar, Swapnil;
- Mikkonen, Piia;
- Oikkonen, Jaana;
- Yilin Li;
- Pikkusaari, Sanna;
- Wennerberg, Krister;
- Hynninen, Johanna;
- Grenman, Seija;
- Huhtinen, Kaisa;
- Auranen, Annika;
- Carpén, Olli;
- Kaipio, Katja
Publication type:
Article
18F-FDG-PET/CT based total metabolic tumor volume change during neoadjuvant chemotherapy predicts outcome in advanced epithelial ovarian cancer.
Published in:
European Journal of Nuclear Medicine & Molecular Imaging, 2018, v. 45, n. 7, p. 1224, doi. 10.1007/s00259-018-3961-z
By:
- Vallius, Tuulia;
- Hynninen, Johanna;
- Kemppainen, Jukka;
- Alves, Victor;
- Auranen, Kari;
- Matomäki, Jaakko;
- Oksa, Sinikka;
- Virtanen, Johanna;
- Grénman, Seija;
- Auranen, Annika;
- Seppänen, Marko
Publication type:
Article
qSNE: quadratic rate t-SNE optimizer with automatic parameter tuning for large datasets.
Published in:
Bioinformatics, 2020, v. 36, n. 20, p. 5086, doi. 10.1093/bioinformatics/btaa637
By:
- Häkkinen, Antti;
- Koiranen, Juha;
- Casado, Julia;
- Kaipio, Katja;
- Lehtonen, Oskari;
- Petrucci, Eleonora;
- Hynninen, Johanna;
- Hietanen, Sakari;
- Carpén, Olli;
- Pasquini, Luca;
- Biffoni, Mauro;
- Lehtonen, Rainer;
- Hautaniemi, Sampsa
Publication type:
Article
Identifying differentially methylated sites in samples with varying tumor purity.
Published in:
Bioinformatics, 2018, v. 34, n. 18, p. 3078, doi. 10.1093/bioinformatics/bty310
By:
- Häkkinen, Antti;
- Alkodsi, Amjad;
- Facciotto, Chiara;
- Zhang, Kaiyang;
- Kaipio, Katja;
- Leppä, Sirpa;
- Carpén, Olli;
- Grénman, Seija;
- Hynninen, Johanna;
- Hietanen, Sakari
Publication type:
Article
Toxicity and therapy outcome associations in LIG3, SLCO1B3, ABCB1, OPRM1 and GSTP1 in high‐grade serous ovarian cancer.
Published in:
Basic & Clinical Pharmacology & Toxicology, 2023, v. 132, n. 6, p. 521, doi. 10.1111/bcpt.13866
By:
- Deng, Feng;
- Laasik, Maren;
- Salminen, Liina;
- Lapatto, Lauri;
- Huhtinen, Kaisa;
- Li, Yilin;
- Hautaniemi, Sampsa;
- Hynninen, Johanna;
- Niemi, Mikko;
- Lehtonen, Rainer
Publication type:
Article
Locus-specific LINE-1 expression in clinical ovarian cancer specimens at the single-cell level.
Published in:
Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-54113-w
By:
- Perkiö, Anna;
- Pradhan, Barun;
- Genc, Fatih;
- Pirttikoski, Anna;
- Pikkusaari, Sanna;
- Erkan, Erdogan Pekcan;
- Falco, Matias Marin;
- Huhtinen, Kaisa;
- Narva, Sara;
- Hynninen, Johanna;
- Kauppi, Liisa;
- Vähärautio, Anna
Publication type:
Article
H&E image analysis pipeline for quantifying morphological features.
Published in:
Journal of Pathology Informatics, 2023, v. 14, p. 1, doi. 10.1016/j.jpi.2023.100339
By:
- Ariotta, Valeria;
- Lehtonen, Oskari;
- Salloum, Shams;
- Micoli, Giulia;
- Lavikka, Kari;
- Rantanen, Ville;
- Hynninen, Johanna;
- Virtanen, Anni;
- Hautaniemi, Sampsa
Publication type:
Article

Found: 29

Diagnostic efficiency of whole-body <sup>18</sup>F-FDG PET/MRI, MRI alone, and SUV and ADC values in staging of primary uterine cervical cancer.

Behavior of FDG-avid supradiaphragmatic lymph nodes in PET/CT throughout primary therapy in advanced serous epithelial ovarian cancer: a prospective study.

ALDH1A1‐related stemness in high‐grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR‐PI3K/aurora kinase inhibitors.

Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance.

FUNGI: FUsioN Gene Integration toolset.

PRISM: recovering cell-type-specific expression profiles from individual composite RNA-seq samples.

Genome-wide quantification of copy-number aberration impact on gene expression in ovarian high-grade serous carcinoma.

Genome-wide quantification of copy-number aberration impact on gene expression in ovarian high-grade serous carcinoma.

A Subset of Secreted Proteins in Ascites Can Predict Platinum-Free Interval in Ovarian Cancer.

A Novel Two-Lipid Signature Is a Strong and Independent Prognostic Factor in Ovarian Cancer.

Exploratory Analysis of CA125-MGL and --STn Glycoforms in the Differential Diagnostics of Pelvic Masses.

Europium Nanoparticle-Based Sialyl-Tn Monoclonal Antibody Discriminates Epithelial Ovarian Cancer--Associated CA125 from Benign Sources.

Glycovariant-based lateral flow immunoassay to detect ovarian cancer–associated serum CA125.

Virtual clinical trials identify effective combination therapies in ovarian cancer.

The feasibility of [<sup>18</sup>F]EF5-PET/CT to image hypoxia in ovarian tumors: a clinical study.

A Nanoparticle-Lectin Immunoassay Improves Discrimination of Serum CA125 from Malignant and Benign Sources.

Network-guided identification of cancer-selective combinatorial therapies in ovarian cancer.

Aggressive and recurrent ovarian cancers upregulate ephrinA5, a non-canonical effector of EphA2 signaling duality.

Author Correction: Virtual clinical trials identify effective combination therapies in ovarian cancer.

REG4 Is Highly Expressed in Mucinous Ovarian Cancer: A Potential Novel Serum Biomarker.

Optimized detection of homologous recombination deficiency improves the prediction of clinical outcomes in cancer.

HE4 in the evaluation of tumor load and prognostic stratification of high grade serous ovarian carcinoma.

Effects of Wee1 inhibitor adavosertib on patient-derived high-grade serous ovarian cancer cells are multiple and independent of homologous recombination status.

<sup>18</sup>F-FDG-PET/CT based total metabolic tumor volume change during neoadjuvant chemotherapy predicts outcome in advanced epithelial ovarian cancer.

qSNE: quadratic rate t-SNE optimizer with automatic parameter tuning for large datasets.

Identifying differentially methylated sites in samples with varying tumor purity.

Toxicity and therapy outcome associations in LIG3, SLCO1B3, ABCB1, OPRM1 and GSTP1 in high‐grade serous ovarian cancer.

Locus-specific LINE-1 expression in clinical ovarian cancer specimens at the single-cell level.

H&E image analysis pipeline for quantifying morphological features.