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AZD5438 a GSK-3a/b and CDK inhibitor is antiapoptotic modulates mitochondrial activity and protects human neurons from mitochondrial toxins.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-35480-2
By:
- Shi, Gongyu;
- Scott, Helen;
- Azhar, Nur Izzah Farhana Mohamad;
- Gialeli, Andriana;
- Clennell, Benjamin;
- Lee, Keng Siang;
- Hurcombe, Jenny;
- Whitcomb, Daniel;
- Coward, Richard;
- Wong, Liang-Fong;
- Cordero-Llana, Oscar;
- Uney, James B.
Publication type:
Article
IGFBP-1 expression is reduced in human type 2 diabetic glomeruli and modulates β1-integrin/FAK signalling in human podocytes.
Published in:
Diabetologia, 2021, v. 64, n. 7, p. 1690, doi. 10.1007/s00125-021-05427-1
By:
- Lay, Abigail C.;
- Hale, Lorna J.;
- Stowell-Connolly, Holly;
- Pope, Robert J. P.;
- Nair, Viji;
- Ju, Wenjun;
- Marquez, Eva;
- Rollason, Ruth;
- Hurcombe, Jenny A.;
- Hayes, Bryony;
- Roberts, Timothy;
- Gillam, Lawrence;
- Allington, Jonathan;
- Nelson, Robert G.;
- Kretzler, Matthias;
- Holly, Jeff M. P.;
- Perks, Claire M.;
- McArdle, Craig A.;
- Welsh, Gavin I.;
- Coward, Richard J. M.
Publication type:
Article
Prolonged exposure of mouse and human podocytes to insulin induces insulin resistance through lysosomal and proteasomal degradation of the insulin receptor.
Published in:
Diabetologia, 2017, v. 60, n. 11, p. 2299, doi. 10.1007/s00125-017-4394-0
By:
- Lay, Abigail;
- Hurcombe, Jenny;
- Betin, Virginie;
- Barrington, Fern;
- Rollason, Ruth;
- Ni, Lan;
- Gillam, Lawrence;
- Pearson, Grace;
- Østergaard, Mette;
- Hamidi, Hellyeh;
- Lennon, Rachel;
- Welsh, Gavin;
- Coward, Richard
Publication type:
Article
Levamisole in steroid-sensitive nephrotic syndrome: usefulness in adult patients and laboratory insights into mechanisms of action via direct action on the kidney podocyte.
Published in:
Clinical Science, 2015, v. 128, n. 12, p. 883, doi. 10.1042/CS20140749
By:
- Lulu Jiang;
- Dasgupta, Ishita;
- Hurcombe, Jenny A.;
- Colyer, Heather F.;
- Mathieson, Peter W.;
- Welsh, Gavin I.
Publication type:
Article
Sphingosine-1-phosphate lyase mutations cause primary adrenal insufficiency and steroid-resistant nephrotic syndrome.
Published in:
2017
By:
- Prasad, Rathi;
- Hadjidemetriou, Irene;
- Maharaj, Avinaash;
- Meimaridou, Eirini;
- Buonocore, Federica;
- Saleem, Moin;
- Hurcombe, Jenny;
- Bierzynska, Agnieszka;
- Barbagelata, Eliana;
- Bergadá, Ignacio;
- Cassinelli, Hamilton;
- Das, Urmi;
- GOSgene;
- Krone, Ruth;
- Hacihamdioglu, Bulent;
- Sari, Erkan;
- Yesilkaya, Ediz;
- Storr, Helen L.;
- Clemente, Maria;
- Fernandez-Cancio, Monica
Publication type:
journal article

Found: 5

AZD5438 a GSK-3a/b and CDK inhibitor is antiapoptotic modulates mitochondrial activity and protects human neurons from mitochondrial toxins.

IGFBP-1 expression is reduced in human type 2 diabetic glomeruli and modulates β1-integrin/FAK signalling in human podocytes.

Prolonged exposure of mouse and human podocytes to insulin induces insulin resistance through lysosomal and proteasomal degradation of the insulin receptor.

Levamisole in steroid-sensitive nephrotic syndrome: usefulness in adult patients and laboratory insights into mechanisms of action via direct action on the kidney podocyte.

Sphingosine-1-phosphate lyase mutations cause primary adrenal insufficiency and steroid-resistant nephrotic syndrome.