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Quantification of the pharmacokinetic-toxicodynamic relationship of oral docetaxel co-administered with ritonavir.
- Published in:
- Investigational New Drugs, 2020, v. 38, n. 5, p. 1526, doi. 10.1007/s10637-020-00935-0
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- Publication type:
- Article
Mass balance and metabolite profiling of 14C-guadecitabine in patients with advanced cancer.
- Published in:
- Investigational New Drugs, 2020, v. 38, n. 4, p. 1085, doi. 10.1007/s10637-019-00854-9
- By:
- Publication type:
- Article
Translational PK-PD modeling analysis of MCLA-128, a HER2/HER3 bispecific monoclonal antibody, to predict clinical efficacious exposure and dose.
- Published in:
- Investigational New Drugs, 2018, v. 36, n. 6, p. 1006, doi. 10.1007/s10637-018-0593-x
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- Publication type:
- Article
Two-stage model-based design of cancer phase I dose escalation trials: evaluation using the phase I program of barasertib (AZD1152)
- Published in:
- 2012
- By:
- Publication type:
- Journal Article
Semi-physiological model describing the hematological toxicity of the anti-cancer agent indisulam.
- Published in:
- Investigational New Drugs, 2005, v. 23, n. 3, p. 225, doi. 10.1007/s10637-005-6730-3
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- Publication type:
- Article
Semiphysiological versus Empirical Modelling of the Population Pharmacokinetics of Free and Total Cefazolin during Pregnancy.
- Published in:
- BioMed Research International, 2014, v. 2014, p. 1, doi. 10.1155/2014/897216
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- Publication type:
- Article
Modulation of the cytochrome P450-mediated metabolism of ifosfamide by ketoconazole and rifampin.
- Published in:
- Clinical Pharmacology & Therapeutics, 2001, v. 70, n. 2, p. 132, doi. 10.1067/mcp.2001.117283
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- Publication type:
- Article
Validation of techniques for the prediction of carboplatin exposure: Application of Bayesian methods<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 2000, v. 67, n. 6, p. 621, doi. 10.1067/mcp.2000.106827
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- Publication type:
- Article
Liquid chromatographic assay for the non-peptidic protease inhibitor tipranavir in plasma.
- Published in:
- Biomedical Chromatography, 2006, v. 20, n. 8, p. 671, doi. 10.1002/bmc.667
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- Publication type:
- Article
Liquid chromatographic assay for the protease inhibitor atazanavir in plasma.
- Published in:
- Biomedical Chromatography, 2006, v. 20, n. 1, p. 72, doi. 10.1002/bmc.530
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- Publication type:
- Article
Toxicological analysis of azide and cyanide for azide intoxications using gas chromatography.
- Published in:
- Basic & Clinical Pharmacology & Toxicology, 2021, v. 128, n. 3, p. 534, doi. 10.1111/bcpt.13523
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- Publication type:
- Article
Severe Lactic Acidosis in a Diabetic Patient after Ethanol Abuse and Floor Cleaner Intake.
- Published in:
- Basic & Clinical Pharmacology & Toxicology, 2014, v. 115, n. 5, p. 472, doi. 10.1111/bcpt.12251
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- Publication type:
- Article
Predicting [<sup>177</sup>Lu]Lu-HA-DOTATATE kidney and tumor accumulation based on [<sup>68</sup>Ga]Ga-HA-DOTATATE diagnostic imaging using semi-physiological population pharmacokinetic modeling.
- Published in:
- EJNMMI Physics, 2023, v. 10, n. 1, p. 1, doi. 10.1186/s40658-023-00565-4
- By:
- Publication type:
- Article
Development of a Framework for Cohort Simulation in Cost-Effectiveness Analyses Using a Multistep Ordinary Differential Equation Solver Algorithm in R.
- Published in:
- 2013
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- Publication type:
- Journal Article
Optimized Dosing: The Next Step in Precision Medicine in Non-Small-Cell Lung Cancer.
- Published in:
- Drugs, 2022, v. 82, n. 1, p. 15, doi. 10.1007/s40265-021-01654-3
- By:
- Publication type:
- Article
Long-term platinum retention after treatment with cisplatin and oxaliplatin.
- Published in:
- BMC Clinical Pharmacology, 2008, v. 8, p. 1, doi. 10.1186/1472-6904-8-7
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- Publication type:
- Article
Pharmacokinetics of PEGasparaginase in Infants with Acute Lymphoblastic Leukemia.
- Published in:
- Pharmaceutical Research, 2024, v. 41, n. 4, p. 711, doi. 10.1007/s11095-024-03693-3
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- Publication type:
- Article
Cortisol as Biomarker for CYP17-Inhibition is Associated with Therapy Outcome of Abiraterone Acetate.
- Published in:
- Pharmaceutical Research, 2023, v. 40, n. 12, p. 3001, doi. 10.1007/s11095-023-03615-9
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- Publication type:
- Article
Exposure–Response Analyses of Olaparib in Real-Life Patients with Ovarian Cancer.
- Published in:
- Pharmaceutical Research, 2023, v. 40, n. 5, p. 1239, doi. 10.1007/s11095-023-03497-x
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- Publication type:
- Article
A Population Pharmacokinetic Modelling Approach to Unravel the Complex Pharmacokinetics of Vincristine in Children.
- Published in:
- Pharmaceutical Research, 2022, v. 39, n. 10, p. 2487, doi. 10.1007/s11095-022-03364-1
- By:
- Publication type:
- Article
Exposure–Response Analysis of Osimertinib in EGFR Mutation Positive Non-Small Cell Lung Cancer Patients in a Real-Life Setting.
- Published in:
- Pharmaceutical Research, 2022, v. 39, n. 10, p. 2507, doi. 10.1007/s11095-022-03355-2
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- Publication type:
- Article
Phase I pharmacological study of continuous chronomodulated capecitabine treatment.
- Published in:
- Pharmaceutical Research, 2020, v. 37, n. 5, p. 1, doi. 10.1007/s11095-020-02828-6
- By:
- Publication type:
- Article
Sialic Acid-Engineered IL4–10 Fusion Protein is Bioactive and Rapidly Cleared from the Circulation.
- Published in:
- Pharmaceutical Research, 2020, v. 37, n. 2, p. 1, doi. 10.1007/s11095-019-2744-y
- By:
- Publication type:
- Article
Exposure to Docetaxel in the Elderly Patient Population: a Population Pharmacokinetic Study.
- Published in:
- Pharmaceutical Research, 2019, v. 36, n. 12, p. N.PAG, doi. 10.1007/s11095-019-2706-4
- By:
- Publication type:
- Article
Does Older Age Lead to Higher Risk for Neutropenia in Patients Treated with Paclitaxel?
- Published in:
- Pharmaceutical Research, 2019, v. 36, n. 12, p. N.PAG, doi. 10.1007/s11095-019-2697-1
- By:
- Publication type:
- Article
Impact of Older Age on the Exposure of Paclitaxel: a Population Pharmacokinetic Study.
- Published in:
- Pharmaceutical Research, 2019, v. 36, n. 2, p. 1, doi. 10.1007/s11095-018-2563-6
- By:
- Publication type:
- Article
Peritoneal metastases from colorectal cancer belong to Consensus Molecular Subtype 4 and are sensitised to oxaliplatin by inhibiting reducing capacity.
- Published in:
- British Journal of Cancer, 2022, v. 126, n. 12, p. 1824, doi. 10.1038/s41416-022-01742-5
- By:
- Publication type:
- Article
Peritoneal metastases from colorectal cancer belong to Consensus Molecular Subtype 4 and are sensitised to oxaliplatin by inhibiting reducing capacity.
- Published in:
- 2022
- By:
- Publication type:
- journal article
Harnessing soft tissue sarcoma with low-dose pazopanib - a matter of blood levels.
- Published in:
- 2018
- By:
- Publication type:
- journal article
The influence of body mass index on the tolerability and effectiveness of full-weight-based paclitaxel chemotherapy in women with early-stage breast cancer.
- Published in:
- Breast Cancer Research & Treatment, 2022, v. 195, n. 3, p. 325, doi. 10.1007/s10549-022-06681-6
- By:
- Publication type:
- Article
Correction to: Therapeutic drug monitoring of oral targeted antineoplastic drugs.
- Published in:
- 2021
- By:
- Publication type:
- Correction Notice
Determination of the absolute bioavailability of oral imatinib using a stable isotopically labeled intravenous imatinib-d8 microdose.
- Published in:
- European Journal of Clinical Pharmacology, 2020, v. 76, n. 8, p. 1075, doi. 10.1007/s00228-020-02888-y
- By:
- Publication type:
- Article
Individualized dosing of oral targeted therapies in oncology is crucial in the era of precision medicine.
- Published in:
- European Journal of Clinical Pharmacology, 2019, v. 75, n. 9, p. 1309, doi. 10.1007/s00228-019-02704-2
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- Publication type:
- Article
The effect of seasonal variation and secretion of sunitinib in sweat on the development of hand–foot syndrome.
- Published in:
- European Journal of Clinical Pharmacology, 2013, v. 69, n. 12, p. 2065, doi. 10.1007/s00228-013-1579-4
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- Publication type:
- Article
Incidence and risk factors for nevirapine-associated rash.
- Published in:
- European Journal of Clinical Pharmacology, 2003, v. 59, n. 5/6, p. 457, doi. 10.1007/s00228-003-0613-3
- By:
- Publication type:
- Article
Reduction of cyclophosphamide bioactivation by thioTEPA: critical sequence-dependency in high-dose chemotherapy regimens.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2000, v. 46, n. 2, p. 119, doi. 10.1007/s002800000132
- By:
- Publication type:
- Article
Lethal morphine intoxication in a patient with a sickle cell crisis and renal impairment: Case report and a review of the literature.
- Published in:
- 2011
- By:
- Publication type:
- Case Study
Azacitidine (Vidaza<sup>®</sup>) in Pediatric Patients with Relapsed Advanced MDS and JMML: Results of a Phase I/II Study by the ITCC Consortium and the EWOG-MDS Group (Study ITCC-015).
- Published in:
- Pediatric Drugs, 2023, v. 25, n. 6, p. 719, doi. 10.1007/s40272-023-00588-5
- By:
- Publication type:
- Article
Simultaneous quantification of cyclophosphamide, 4-hydroxycyclophosphamide, N,N<sup>'</sup>,N<sup>"</sup>-triethylenethiophosphoramide (thiotepa) and N,N<sup>'</sup>,N<sup>"</sup>-triethylenephosphoramide (tepa) in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry
- Published in:
- Journal of Mass Spectrometry, 2004, v. 39, n. 3, p. 262
- By:
- Publication type:
- Article
Molecular Imaging of ABCB1 and ABCG2 Inhibition at the Human Blood-Brain Barrier Using Elacridar and <sup>11</sup>C-Erlotinib PET.
- Published in:
- Journal of Nuclear Medicine, 2018, v. 59, n. 6, p. 973, doi. 10.2967/jnumed.117.195800
- By:
- Publication type:
- Article
Translational pharmacokinetic modelling and simulation for the assessment of duration of contraceptive use after treatment with miltefosine.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2012, v. 67, n. 8, p. 1996, doi. 10.1093/jac/dks164
- By:
- Publication type:
- Article
Use of dried blood spots for the determination of plasma concentrations of nevirapine and efavirenz.
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2012, v. 67, n. 5, p. 1211, doi. 10.1093/jac/dks011
- By:
- Publication type:
- Article
Pharmacokinetics of Gemcitabine and Metabolites in a Patient with Double-Sided Nephrectomy: A Case Report and Review of the Literature.
- Published in:
- 2009
- By:
- Publication type:
- Case Study
Neutropenia and docetaxel exposure in metastatic castration‐resistant prostate cancer patients: A meta‐analysis and evaluation of a clinical cohort.
- Published in:
- Cancer Medicine, 2019, v. 8, n. 4, p. 1406, doi. 10.1002/cam4.2003
- By:
- Publication type:
- Article
Therapeutic drug monitoring guided dosing versus standard dosing of alectinib in advanced ALK positive non-small cell lung cancer patients: Study protocol for an international, multicenter phase IV randomized controlled trial (ADAPT ALEC).
- Published in:
- Frontiers in Oncology, 2023, v. 13, p. 1, doi. 10.3389/fonc.2023.1136221
- By:
- Publication type:
- Article
Evaluating the Clinical Impact and Feasibility of Therapeutic Drug Monitoring of Pazopanib in a Real-World Soft-Tissue Sarcoma Cohort.
- Published in:
- Clinical Pharmacokinetics, 2024, v. 63, n. 7, p. 1045, doi. 10.1007/s40262-024-01399-8
- By:
- Publication type:
- Article
Population Pharmacokinetics and Target Attainment of Allopurinol and Oxypurinol Before, During, and After Cardiac Surgery with Cardiopulmonary Bypass in Neonates with Critical Congenital Heart Disease.
- Published in:
- Clinical Pharmacokinetics, 2024, v. 63, n. 8, p. 1205, doi. 10.1007/s40262-024-01401-3
- By:
- Publication type:
- Article
Therapeutic Drug Monitoring of Kinase Inhibitors in Oncology.
- Published in:
- Clinical Pharmacokinetics, 2023, v. 62, n. 10, p. 1333, doi. 10.1007/s40262-023-01293-9
- By:
- Publication type:
- Article
CYP3A4*22 Genotype-Guided Dosing of Kinase Inhibitors in Cancer Patients.
- Published in:
- Clinical Pharmacokinetics, 2023, v. 62, n. 8, p. 1129, doi. 10.1007/s40262-023-01260-4
- By:
- Publication type:
- Article
Predicting Chemotherapy Distribution into Breast Milk for Breastfeeding Women Using a Population Pharmacokinetic Approach.
- Published in:
- Clinical Pharmacokinetics, 2023, v. 62, n. 7, p. 969, doi. 10.1007/s40262-023-01251-5
- By:
- Publication type:
- Article