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Epigenetic signals associated with delirium replicated across four independent cohorts.
Published in:
Translational Psychiatry, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41398-024-02986-w
By:
- Nishizawa, Yoshitaka;
- Thompson, Kaitlyn C.;
- Yamanashi, Takehiko;
- Wahba, Nadia E.;
- Saito, Taku;
- Marra, Pedro S.;
- Nagao, Takaaki;
- Nishiguchi, Tsuyoshi;
- Shibata, Kazuki;
- Yamanishi, Kyosuke;
- Hughes, Christopher G.;
- Pandharipande, Pratik;
- Cho, Hyunkeun;
- Howard III, Matthew A.;
- Kawasaki, Hiroto;
- Toda, Hiroyuki;
- Kanazawa, Tetsufumi;
- Iwata, Masaaki;
- Shinozaki, Gen
Publication type:
Article
The Association of Nonmodifiable Patient Factors on Antipsychotic Medication use in the Intensive Care Unit.
Published in:
Journal of Intensive Care Medicine, 2024, v. 39, n. 2, p. 176, doi. 10.1177/08850666231198030
By:
- Connell, Jennifer;
- McCann, Brittany;
- Feng, Xiaoke;
- Shotwell, Matthew S.;
- Hughes, Christopher G.;
- Boncyk, Christina S.
Publication type:
Article
Correlation of the Critical Care Pain Observation Tool and Numeric Rating Scale in Intensive Care Unit Patients.
Published in:
Journal of Intensive Care Medicine, 2024, v. 39, n. 1, p. 12, doi. 10.1177/08850666231187336
By:
- Stollings, Joanna L;
- Rumbaugh, Kelli A;
- Wang, Li;
- Hayhurst, Christina J;
- Ely, E Wesley;
- Hughes, Christopher G
Publication type:
Article
Quantifying uncertainties in land surface temperature and emissivity retrievals from ASTER and MODIS thermal infrared data.
Published in:
Journal of Geophysical Research. Atmospheres, 2012, v. 117, n. D23, p. n/a, doi. 10.1029/2012JD018506
By:
- Hulley, Glynn C.;
- Hughes, Christopher G.;
- Hook, Simon J.
Publication type:
Article
Sedative Plasma Concentrations and Delirium Risk in Critical Illness.
Published in:
2018
By:
- Stollings, Joanna L.;
- Thompson, Jennifer L.;
- Ferrell, Benjamin A.;
- Scheinin, Mika;
- Wilkinson, Grant R.;
- Hughes, Christopher G.;
- Shintani, Ayumi K.;
- Ely, E. Wesley;
- Girard, Timothy D.;
- Pandharipande, Pratik P.;
- Patel, Mayur B.
Publication type:
journal article
Individualized Treatment Effects of Bougie versus Stylet for Tracheal Intubation in Critical Illness.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2023, v. 207, n. 12, p. 1602, doi. 10.1164/rccm.202209-1799OC
By:
- Seitz, Kevin P.;
- Spicer, Alexandra B.;
- Casey, Jonathan D.;
- Buell, Kevin G.;
- Qian, Edward T.;
- Graham Linck, Emma J.;
- Driver, Brian E.;
- Self, Wesley H.;
- Ginde, Adit A.;
- Trent, Stacy A.;
- Gandotra, Sheetal;
- Smith, Lane M.;
- Page, David B.;
- Vonderhaar, Derek J.;
- West, Jason R.;
- Joffe, Aaron M.;
- Doerschug, Kevin C.;
- Hughes, Christopher G.;
- Whitson, Micah R.;
- Prekker, Matthew E.
Publication type:
Article
The Conundrum of Pain, Opiate Use, and Delirium: Analgosedation or Analgesia-First Approach?
Published in:
2021
By:
- Hayhurst, Christina J.;
- Hughes, Christopher G.;
- Pandharipande, Pratik P.
Publication type:
Editorial
Inflammation and Coagulation during Critical Illness and Long-Term Cognitive Impairment and Disability.
Published in:
2021
By:
- Brummel, Nathan E.;
- Hughes, Christopher G.;
- Thompson, Jennifer L.;
- Jackson, James C.;
- Pandharipande, Pratik;
- McNeil, J. Brennan;
- Raman, Rameela;
- Orun, Onur M.;
- Ware, Lorraine B.;
- Bernard, Gordon R.;
- Ely, E. Wesley;
- Girard, Timothy D.
Publication type:
journal article
Inflammation and Coagulation during Critical Illness and Long-Term Cognitive Impairment and Disability.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2021, v. 203, n. 6, p. E1
By:
- Brummel, Nathan E.;
- Hughes, Christopher G.;
- Thompson, Jennifer L.;
- Jackson, James C.;
- Pandharipande, Pratik;
- Brennan McNeil, J.;
- Raman, Rameela;
- Orun, Onur M.;
- Ware, Lorraine B.;
- Bernard, Gordon R.;
- Ely, E. Wesley;
- Girard, Timothy D.
Publication type:
Article
Incidence and Risk Factors for Intensive Care Unit-related Post-traumatic Stress Disorder in Veterans and Civilians.
Published in:
2016
By:
- Patel, Mayur B.;
- Jackson, James C.;
- Morandi, Alessandro;
- Girard, Timothy D.;
- Hughes, Christopher G.;
- Thompson, Jennifer L.;
- Kiehl, Amy L.;
- Elstad, Mark R.;
- Wasserstein, Mitzi L.;
- Goodman, Richard B.;
- Beckham, Jean C.;
- Chandrasekhar, Rameela;
- Dittus, Robert S.;
- Wesley Ely, E.;
- Pandharipande, Pratik P.;
- Ely, E Wesley
Publication type:
journal article
Design and Rationale of the Sevoflurane for Sedation in Acute Respiratory Distress Syndrome (SESAR) Randomized Controlled Trial.
Published in:
Journal of Clinical Medicine, 2022, v. 11, n. 10, p. 2796, doi. 10.3390/jcm11102796
By:
- Blondonnet, Raiko;
- Simand, Laure-Anne;
- Vidal, Perine;
- Borao, Lucile;
- Bourguignon, Nathalie;
- Morand, Dominique;
- Bernard, Lise;
- Roszyk, Laurence;
- Audard, Jules;
- Godet, Thomas;
- Monsel, Antoine;
- Garnier, Marc;
- Quesnel, Christophe;
- Bazin, Jean-Etienne;
- Sapin, Vincent;
- Bastarache, Julie A.;
- Ware, Lorraine B.;
- Hughes, Christopher G.;
- Pandharipande, Pratik P.;
- Ely, E. Wesley
Publication type:
Article
DNA methylation in the inflammatory genes after neurosurgery and diagnostic ability of post-operative delirium.
Published in:
Translational Psychiatry, 2021, v. 11, p. 1, doi. 10.1038/s41398-021-01752-6
By:
- Yamanashi, Takehiko;
- Nagao, Takaaki;
- Wahba, Nadia E.;
- Marra, Pedro S.;
- Crutchley, Kaitlyn J.;
- Meyer, Alissa A.;
- Andreasen, Ally J.;
- Hellman, Mandy M.;
- Jellison, Sydney S.;
- Hughes, Christopher G.;
- Pandharipande, Pratik P.;
- Howard, III, Matthew A.;
- Kawasaki, Hiroto;
- Iwata, Masaaki;
- Hefti, Marco M.;
- Shinozaki, Gen
Publication type:
Article
Embarras and Disconvenance in Poussin’s Rebecca and Eliezar at the Well.
Published in:
Art History, 2001, v. 24, n. 4, doi. 10.1111/1467-8365.00279
By:
- Hughes, Christopher G.
Publication type:
Article
Abstracts.
Published in:
2001
By:
- Greeley, Robin Adele;
- Hughes, Christopher G.;
- Cole, Michael;
- Karlholm, Dan;
- Marlowe, Elizabeth
Publication type:
Abstract
Sedation in the intensive care setting.
Published in:
Clinical Pharmacology, 2012, v. 4, p. 53
By:
- Hughes, Christopher G.;
- McGrane, Stuart;
- Pandharipande, Pratik P.
Publication type:
Article
Plasma biomarkers of inflammation, coagulation, and brain injury as predictors of delirium duration in older hospitalized patients.
Published in:
PLoS ONE, 2019, v. 14, n. 12, p. N.PAG, doi. 10.1371/journal.pone.0226412
By:
- McNeil, J. Brennan;
- Hughes, Christopher G.;
- Girard, Timothy;
- Ware, Lorraine B.;
- Ely, E. Wesley;
- Chandrasekhar, Rameela;
- Han, Jin H.
Publication type:
Article
Statistical analysis plan for the Maximizing the Efficacy of Sedation and Reducing Neurological Dysfunction and Mortality in Septic Patients with Acute Respiratory Failure trial.
Published in:
Critical Care & Resuscitation, 2020, v. 22, n. 1, p. 63, doi. 10.51893/2020.1.oa7
By:
- Chandrasekhar, Rameela;
- Hughes, Christopher G.;
- Pun, Brenda T.;
- Orun, Onur M.;
- Ely, E. Wesley;
- Pandharipande, Pratik P.
Publication type:
Article
Systemic inflammation and delirium during critical illness.
Published in:
Intensive Care Medicine, 2024, v. 50, n. 5, p. 687, doi. 10.1007/s00134-024-07388-6
By:
- Brummel, Nathan E.;
- Hughes, Christopher G.;
- McNeil, J. Brennan;
- Pandharipande, Pratik P.;
- Thompson, Jennifer L.;
- Orun, Onur M.;
- Raman, Rameela;
- Ware, Lorraine B.;
- Bernard, Gordon R.;
- Harrison, Fiona E.;
- Ely, E. Wesley;
- Girard, Timothy D.
Publication type:
Article
Relationships between markers of neurologic and endothelial injury during critical illness and long-term cognitive impairment and disability.
Published in:
2018
By:
- Hughes, Christopher G.;
- Patel, Mayur B.;
- Brummel, Nathan E.;
- Thompson, Jennifer L.;
- McNeil, J. Brennan;
- Pandharipande, Pratik P.;
- Jackson, James C.;
- Chandrasekhar, Rameela;
- Ware, Lorraine B.;
- Ely, E. Wesley;
- Girard, Timothy D.
Publication type:
journal article
The genome‐wide DNA methylation profiles among neurosurgery patients with and without post‐operative delirium.
Published in:
Psychiatry & Clinical Neurosciences, 2023, v. 77, n. 1, p. 48, doi. 10.1111/pcn.13495
By:
- Yamanashi, Takehiko;
- Crutchley, Kaitlyn J.;
- Wahba, Nadia E.;
- Nagao, Takaaki;
- Marra, Pedro S.;
- Akers, Cade C.;
- Sullivan, Eleanor J.;
- Iwata, Masaaki;
- Howard, Mathew A;
- Cho, Hyunkeun R.;
- Kawasaki, Hiroto;
- Hughes, Christopher G.;
- Pandharipande, Pratik P.;
- Hefti, Marco M.;
- Shinozaki, Gen
Publication type:
Article
Association between cholinesterase activity and critical illness brain dysfunction.
Published in:
Critical Care, 2022, v. 26, n. 1, p. 1, doi. 10.1186/s13054-022-04260-1
By:
- Hughes, Christopher G.;
- Boncyk, Christina S.;
- Fedeles, Benjamin;
- Pandharipande, Pratik P.;
- Chen, Wencong;
- Patel, Mayur B.;
- Brummel, Nathan E.;
- Jackson, James C.;
- Raman, Rameela;
- Ely, E. Wesley;
- Girard, Timothy D.
Publication type:
Article
Only a Small Subset of Sedation-related Delirium Is Innocuous: We Cannot Let Our Guard Down.
Published in:
2014
By:
- Pandharipande, Pratik P;
- Hughes, Christopher G;
- Girard, Timothy D
Publication type:
Journal Article
Only a Small Subset of Sedation-related Delirium Is Innocuous: We Cannot Let Our Guard Down.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2014, v. 189, n. 11, p. 1443, doi. 10.1164/rccm.201403-0506le
By:
- Pandharipand, Pratik P.;
- Hughes, Christopher G.;
- Girard, Timothy D.
Publication type:
Article
Avoiding Inappropriate Medication Prescription in Older Intensive Care Survivors.
Published in:
Journal of Clinical Outcomes Management, 2018, v. 25, n. 2, p. 67
By:
- Marra, Annachiara;
- Hayhurst, Christina J.;
- Hughes, Christopher G.;
- Marengoni, Alessandra;
- Bellelli, Giuseppe;
- Pandharipande, Pratik;
- Morandi, Alessandro
Publication type:
Article
Lunar swirls: Examining crustal magnetic anomalies and space weathering trends.
Published in:
Journal of Geophysical Research. Planets, 2011, v. 116, n. E2, p. n/a, doi. 10.1029/2010JE003656
By:
- Blewett, David T.;
- Coman, Ecaterina I.;
- Hawke, B. Ray;
- Gillis-Davis, Jeffrey J.;
- Purucker, Michael E.;
- Hughes, Christopher G.
Publication type:
Article
Effect of Use of a Bougie vs Endotracheal Tube With Stylet on Successful Intubation on the First Attempt Among Critically Ill Patients Undergoing Tracheal Intubation: A Randomized Clinical Trial.
Published in:
JAMA: Journal of the American Medical Association, 2021, v. 326, n. 24, p. 2488, doi. 10.1001/jama.2021.22002
By:
- Driver, Brian E.;
- Semler, Matthew W.;
- Self, Wesley H.;
- Ginde, Adit A.;
- Trent, Stacy A.;
- Gandotra, Sheetal;
- Smith, Lane M.;
- Page, David B.;
- Vonderhaar, Derek J.;
- West, Jason R.;
- Joffe, Aaron M.;
- Mitchell, Steven H.;
- Doerschug, Kevin C.;
- Hughes, Christopher G.;
- High, Kevin;
- Landsperger, Janna S.;
- Jackson, Karen E.;
- Howell, Michelle P.;
- Robison, Sarah W.;
- Gaillard, John P.
Publication type:
Article
Perioperative Neurocognitive Disorders in Adults Requiring Cardiac Surgery: Screening, Prevention, and Management.
Published in:
Seminars in Cardiothoracic & Vascular Anesthesia, 2023, v. 27, n. 1, p. 25, doi. 10.1177/10892532221127812
By:
- Rengel, Kimberly F.;
- Boncyk, Christina S.;
- DiNizo, Daniella;
- Hughes, Christopher G.
Publication type:
Article
The American Geriatrics Society/National Institute on Aging Bedside-to-Bench Conference: Research Agenda on Delirium in Older Adults.
Published in:
2015
By:
- Alessi, Cathy;
- Auerbach, Andrew;
- Avelino‐Silva, Thiago J.;
- Boustani, Malaz;
- Brown, Emery;
- Brummel, Nathan E.;
- Campbell, Noll;
- Cunningham, Colm;
- Davis, Daniel;
- Deiner, Stacie;
- Dugan, Laura;
- Eldadah, Basil;
- Wesley Ely, E.;
- Fick, Donna;
- Gould, Robert;
- Hansen, Jennie Chin;
- Han, Jin Ho;
- Hayden, Kathleen M.;
- Hopkins, Ramona O.;
- Hughes, Christopher G.
Publication type:
Proceeding
Elderly Patients and Management in Intensive Care Units (ICU): Clinical Challenges.
Published in:
Clinical Interventions in Aging, 2023, v. 18, p. 93, doi. 10.2147/CIA.S365968
By:
- Brunker, Lucille B;
- Boncyk, Christina S;
- Rengel, Kimberly F;
- Hughes, Christopher G
Publication type:
Article
Effets d’un centre de soins chirurgicaux périopératoires en anesthésie pour les arthroplasties totales du genou et de la hanche dans un hôpital pour anciens combattants : une étude de cohorte d’amélioration de la qualité avant et après.
Published in:
2021
By:
- Alvis, Bret D.;
- Amsler, Roland G.;
- Leisy, Philip J.;
- Feng, Xiaoke;
- Shotwell, Matthew S.;
- Pandharipande, Pratik P.;
- Ajmal, Muhammad;
- McHugh, Michael;
- Walia, Ann;
- Hughes, Christopher G.
Publication type:
journal article

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